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Protein

Cold shock protein CspA

Gene

cspA

Organism
Shigella flexneri
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to and stimulates the transcription of the CCAAT-containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3' (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processStress response, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Cold shock protein CspA
Short name:
CSP-A
Alternative name(s):
7.4 kDa cold shock protein
CS7.4
Gene namesi
Name:cspA
Ordered Locus Names:SF3589, S4179
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001002392 – 70Cold shock protein CspAAdd BLAST69

Proteomic databases

PRIDEiP0A9Y4

Expressioni

Inductioni

In response to low temperature.By similarity

Structurei

3D structure databases

ProteinModelPortaliP0A9Y4
SMRiP0A9Y4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 67CSDAdd BLAST61

Phylogenomic databases

eggNOGiENOG4105VEQ Bacteria
COG1278 LUCA
HOGENOMiHOG000070674
KOiK03704
OMAiHHSAINS

Family and domain databases

CDDicd04458 CSP_CDS, 1 hit
InterProiView protein in InterPro
IPR019844 Cold-shock_CS
IPR012156 Cold_shock_CspA
IPR011129 CSD
IPR002059 CSP_DNA-bd
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF00313 CSD, 1 hit
PIRSFiPIRSF002599 Cold_shock_A, 1 hit
PRINTSiPR00050 COLDSHOCK
SMARTiView protein in SMART
SM00357 CSP, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS00352 CSD_1, 1 hit
PS51857 CSD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A9Y4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGKMTGIVK WFNADKGFGF ITPDDGSKDV FVHFSAIQND GYKSLDEGQK
60 70
VSFTIESGAK GPAAGNVTSL
Length:70
Mass (Da):7,403
Last modified:January 23, 2007 - v2
Checksum:iCED47F00BF18A49B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN45040.1
AE014073 Genomic DNA Translation: AAP19147.1
U60037 Genomic DNA Translation: AAC80241.1
RefSeqiNP_709333.1, NC_004337.2
WP_000014594.1, NZ_QDEA01000082.1

Genome annotation databases

EnsemblBacteriaiAAN45040; AAN45040; SF3589
AAP19147; AAP19147; S4179
GeneIDi1026303
32213729
KEGGisfl:SF3589
sfx:S4179
PATRICifig|198214.7.peg.4236

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN45040.1
AE014073 Genomic DNA Translation: AAP19147.1
U60037 Genomic DNA Translation: AAC80241.1
RefSeqiNP_709333.1, NC_004337.2
WP_000014594.1, NZ_QDEA01000082.1

3D structure databases

ProteinModelPortaliP0A9Y4
SMRiP0A9Y4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP0A9Y4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN45040; AAN45040; SF3589
AAP19147; AAP19147; S4179
GeneIDi1026303
32213729
KEGGisfl:SF3589
sfx:S4179
PATRICifig|198214.7.peg.4236

Phylogenomic databases

eggNOGiENOG4105VEQ Bacteria
COG1278 LUCA
HOGENOMiHOG000070674
KOiK03704
OMAiHHSAINS

Family and domain databases

CDDicd04458 CSP_CDS, 1 hit
InterProiView protein in InterPro
IPR019844 Cold-shock_CS
IPR012156 Cold_shock_CspA
IPR011129 CSD
IPR002059 CSP_DNA-bd
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF00313 CSD, 1 hit
PIRSFiPIRSF002599 Cold_shock_A, 1 hit
PRINTSiPR00050 COLDSHOCK
SMARTiView protein in SMART
SM00357 CSP, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
PROSITEiView protein in PROSITE
PS00352 CSD_1, 1 hit
PS51857 CSD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCSPA_SHIFL
AccessioniPrimary (citable) accession number: P0A9Y4
Secondary accession number(s): P15277, P37410, Q54170
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: January 23, 2007
Last modified: October 10, 2018
This is version 84 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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