Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable multidrug ABC transporter ATP-binding protein YbhF

Gene

ybhF

Organism
Shigella flexneri
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably responsible for energy coupling to the transport system.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi40 – 47ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi362 – 369ATP 2PROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable multidrug ABC transporter ATP-binding protein YbhFBy similarity
Gene namesi
Name:ybhF
Ordered Locus Names:SF0744, S0785
OrganismiShigella flexneri
Taxonomic identifieri623 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella
Proteomesi
  • UP000002673 Componenti: Chromosome
  • UP000001006 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000931571 – 578Probable multidrug ABC transporter ATP-binding protein YbhFAdd BLAST578

Interactioni

Subunit structurei

The complex is probably composed of two ATP-binding proteins (YbhF) and two transmembrane proteins (YbhR and YbhS).By similarity

Structurei

3D structure databases

ProteinModelPortaliP0A9U2
SMRiP0A9U2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 237ABC transporter 1PROSITE-ProRule annotationAdd BLAST232
Domaini330 – 559ABC transporter 2PROSITE-ProRule annotationAdd BLAST230

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CJ1 Bacteria
COG1131 LUCA
HOGENOMiHOG000014887
KOiK01990

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

P0A9U2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNDAVITLNG LEKRFPGMDK PAVAPLDCTI HAGYVTGLVG PDGAGKTTLM
60 70 80 90 100
RMLAGLLKPD SGSATVIGFD PIKNDGALHA VLGYMPQKFG LYEDLTVMEN
110 120 130 140 150
LNLYADLRSV TGEARKQTFA RLLEFTSLGP FTGRLAGKLS GGMKQKLGLA
160 170 180 190 200
CTLVGEPKVL LLDEPGVGVD PISRRELWQM VHELAGEGML ILWSTSYLDE
210 220 230 240 250
AEQCRDVLLM NEGELLYQGE PKALTQTMAG RSFLMTSPHE GNRKLLQRAL
260 270 280 290 300
KLPQVSDGMI QGKSVRLILK KEATPDDIRH ADGMPEININ ETTPRFEDAF
310 320 330 340 350
IDLLGGAGTS ESPLGAILHT VEGTPGETVI EAKELTKKFG DFAATDHVNF
360 370 380 390 400
AVKRGEIFGL LGPNGAGKST TFKMMCGLLV PTSGQALVLG MDLKESSGKA
410 420 430 440 450
RQHLGYMAQK FSLYGNLTVE QNLRFFSGVY GLRGRAQNEK ISRMSEAFGL
460 470 480 490 500
KSIASHATDE LPLGFKQRLA LACSLMHEPD ILFLDEPTSG VDPLTRREFW
510 520 530 540 550
LHINSMVEKG VTVMVTTHFM DEAEYCDRIG LVYRGKLIAS GTPDDLKAQS
560 570
ANDEQPDPTM EQAFIQLIHD WDKEHSNE
Length:578
Mass (Da):63,132
Last modified:July 19, 2005 - v1
Checksum:iDB3B3FA213490F3C
GO

Sequence cautioni

The sequence AAN42379 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAP16256 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti44A → E in AAP16256 (PubMed:12704152).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN42379.1 Different initiation.
AE014073 Genomic DNA Translation: AAP16256.1 Different initiation.
RefSeqiNP_706672.1, NC_004337.2
WP_000996107.1, NZ_UELP01000039.1

Genome annotation databases

EnsemblBacteriaiAAN42379; AAN42379; SF0744
AAP16256; AAP16256; S0785
GeneIDi1023711
KEGGisfl:SF0744
sfx:S0785
PATRICifig|198214.7.peg.865

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE005674 Genomic DNA Translation: AAN42379.1 Different initiation.
AE014073 Genomic DNA Translation: AAP16256.1 Different initiation.
RefSeqiNP_706672.1, NC_004337.2
WP_000996107.1, NZ_UELP01000039.1

3D structure databases

ProteinModelPortaliP0A9U2
SMRiP0A9U2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAN42379; AAN42379; SF0744
AAP16256; AAP16256; S0785
GeneIDi1023711
KEGGisfl:SF0744
sfx:S0785
PATRICifig|198214.7.peg.865

Phylogenomic databases

eggNOGiENOG4105CJ1 Bacteria
COG1131 LUCA
HOGENOMiHOG000014887
KOiK01990

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiYBHF_SHIFL
AccessioniPrimary (citable) accession number: P0A9U2
Secondary accession number(s): P75776, Q9R7S3, Q9R7S4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: November 7, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again