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Protein

High-affinity branched-chain amino acid transport ATP-binding protein LivG

Gene

livG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the leucine-specific transport system.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi38 – 45ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:LIVG-MONOMER
MetaCyc:LIVG-MONOMER

Protein family/group databases

TCDBi3.A.1.4.1 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
High-affinity branched-chain amino acid transport ATP-binding protein LivG
Alternative name(s):
LIV-I protein G
Gene namesi
Name:livG
Ordered Locus Names:b3455, JW3420
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10537 livG

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000924061 – 255High-affinity branched-chain amino acid transport ATP-binding protein LivGAdd BLAST255

Proteomic databases

PaxDbiP0A9S7
PRIDEiP0A9S7

Interactioni

Protein-protein interaction databases

BioGridi4261119, 381 interactors
IntActiP0A9S7, 6 interactors
STRINGi316385.ECDH10B_3629

Structurei

3D structure databases

ProteinModelPortaliP0A9S7
SMRiP0A9S7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 254ABC transporterPROSITE-ProRule annotationAdd BLAST249

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Phylogenomic databases

eggNOGiENOG4105C0Z Bacteria
COG0411 LUCA
InParanoidiP0A9S7
KOiK01995
PhylomeDBiP0A9S7

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR032823 BCA_ABC_TP_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PF12399 BCA_ABC_TP_C, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P0A9S7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQPLLSVNG LMMRFGGLLA VNNVNLELYP QEIVSLIGPN GAGKTTVFNC
60 70 80 90 100
LTGFYKPTGG TILLRDQHLE GLPGQQIARM GVVRTFQHVR LFREMTVIEN
110 120 130 140 150
LLVAQHQQLK TGLFSGLLKT PSFRRAQSEA LDRAATWLER IGLLEHANRQ
160 170 180 190 200
ASNLAYGDQR RLEIARCMVT QPEILMLDEP AAGLNPKETK ELDELIAELR
210 220 230 240 250
NHHNTTILLI EHDMKLVMGI SDRIYVVNQG TPLANGTPEQ IRNNPDVIRA

YLGEA
Length:255
Mass (Da):28,427
Last modified:July 19, 2005 - v1
Checksum:iD05B2F344DF7CA85
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti130A → R in AAA83886 (PubMed:2195019).Curated1
Sequence conflicti237T → S in AAA83886 (PubMed:2195019).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05516 Genomic DNA Translation: AAA83886.1
U00039 Genomic DNA Translation: AAB18430.1
U00096 Genomic DNA Translation: AAC76480.1
AP009048 Genomic DNA Translation: BAE77838.1
PIRiF37074
RefSeqiNP_417912.1, NC_000913.3
WP_000082101.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76480; AAC76480; b3455
BAE77838; BAE77838; BAE77838
GeneIDi947967
KEGGiecj:JW3420
eco:b3455
PATRICifig|511145.12.peg.3553

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J05516 Genomic DNA Translation: AAA83886.1
U00039 Genomic DNA Translation: AAB18430.1
U00096 Genomic DNA Translation: AAC76480.1
AP009048 Genomic DNA Translation: BAE77838.1
PIRiF37074
RefSeqiNP_417912.1, NC_000913.3
WP_000082101.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliP0A9S7
SMRiP0A9S7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261119, 381 interactors
IntActiP0A9S7, 6 interactors
STRINGi316385.ECDH10B_3629

Protein family/group databases

TCDBi3.A.1.4.1 the atp-binding cassette (abc) superfamily

Proteomic databases

PaxDbiP0A9S7
PRIDEiP0A9S7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76480; AAC76480; b3455
BAE77838; BAE77838; BAE77838
GeneIDi947967
KEGGiecj:JW3420
eco:b3455
PATRICifig|511145.12.peg.3553

Organism-specific databases

EchoBASEiEB0532
EcoGeneiEG10537 livG

Phylogenomic databases

eggNOGiENOG4105C0Z Bacteria
COG0411 LUCA
InParanoidiP0A9S7
KOiK01995
PhylomeDBiP0A9S7

Enzyme and pathway databases

BioCyciEcoCyc:LIVG-MONOMER
MetaCyc:LIVG-MONOMER

Miscellaneous databases

PROiPR:P0A9S7

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR032823 BCA_ABC_TP_C
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00005 ABC_tran, 1 hit
PF12399 BCA_ABC_TP_C, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiLIVG_ECOLI
AccessioniPrimary (citable) accession number: P0A9S7
Secondary accession number(s): P22730, Q2M7B8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: November 7, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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