UniProtKB - P0A972 (CSPE_ECOLI)
Protein
Cold shock-like protein CspE
Gene
cspE
Organism
Escherichia coli (strain K12)
Status
Functioni
GO - Molecular functioni
- nucleic acid binding Source: GO_Central
- poly(A) binding Source: EcoCyc
- RNA binding Source: EcoliWiki
- single-stranded DNA binding Source: EcoCyc
- transcription antitermination factor activity, RNA binding Source: EcoliWiki
GO - Biological processi
- negative regulation of DNA-templated transcription, termination Source: EcoliWiki
- regulation of gene expression Source: GO_Central
Keywordsi
Molecular function | Activator, DNA-binding |
Biological process | Transcription, Transcription regulation |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12179-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Cold shock-like protein CspEShort name: CSP-E |
Gene namesi | Name:cspE Synonyms:gicA, msmC Ordered Locus Names:b0623, JW0618 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm By similarity
GO - Cellular componenti
- cytosol Source: EcoCyc
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed1 Publication | |||
ChainiPRO_0000100253 | 2 – 69 | Cold shock-like protein CspEAdd BLAST | 68 |
Proteomic databases
jPOSTi | P0A972 |
PaxDbi | P0A972 |
PRIDEi | P0A972 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260642, 29 interactors |
DIPi | DIP-47834N |
IntActi | P0A972, 49 interactors |
STRINGi | 511145.b0623 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 66 | CSDAdd BLAST | 61 |
Phylogenomic databases
eggNOGi | COG1278, Bacteria |
HOGENOMi | CLU_117621_2_1_6 |
InParanoidi | P0A972 |
PhylomeDBi | P0A972 |
Family and domain databases
CDDi | cd04458, CSP_CDS, 1 hit |
InterProi | View protein in InterPro IPR012156, Cold_shock_CspA IPR011129, CSD IPR019844, CSD_1 IPR002059, CSP_DNA-bd IPR012340, NA-bd_OB-fold |
Pfami | View protein in Pfam PF00313, CSD, 1 hit |
PIRSFi | PIRSF002599, Cold_shock_A, 1 hit |
PRINTSi | PR00050, COLDSHOCK |
SMARTi | View protein in SMART SM00357, CSP, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
PROSITEi | View protein in PROSITE PS00352, CSD_1, 1 hit PS51857, CSD_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P0A972-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSKIKGNVKW FNESKGFGFI TPEDGSKDVF VHFSAIQTNG FKTLAEGQRV
60
EFEITNGAKG PSAANVIAL
Sequence cautioni
The sequence AAB40823 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 58 | A → R (Ref. 2) Curated | 1 |
Mass spectrometryi
Molecular mass is 7331 Da. Determined by ESI. 1 Publication
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D28497 Genomic DNA Translation: BAA05856.1 L29054 Genomic DNA Translation: AAA67556.1 S83396 Genomic DNA Translation: AAN86720.1 U82598 Genomic DNA Translation: AAB40823.1 Different initiation. U00096 Genomic DNA Translation: AAC73724.1 AP009048 Genomic DNA Translation: BAA35266.1 |
PIRi | S49050 |
RefSeqi | NP_415156.1, NC_000913.3 WP_000034825.1, NZ_STEB01000031.1 |
Genome annotation databases
EnsemblBacteriai | AAC73724; AAC73724; b0623 BAA35266; BAA35266; BAA35266 |
GeneIDi | 52075941 947024 |
KEGGi | ecj:JW0618 eco:b0623 |
PATRICi | fig|1411691.4.peg.1645 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D28497 Genomic DNA Translation: BAA05856.1 L29054 Genomic DNA Translation: AAA67556.1 S83396 Genomic DNA Translation: AAN86720.1 U82598 Genomic DNA Translation: AAB40823.1 Different initiation. U00096 Genomic DNA Translation: AAC73724.1 AP009048 Genomic DNA Translation: BAA35266.1 |
PIRi | S49050 |
RefSeqi | NP_415156.1, NC_000913.3 WP_000034825.1, NZ_STEB01000031.1 |
3D structure databases
SMRi | P0A972 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260642, 29 interactors |
DIPi | DIP-47834N |
IntActi | P0A972, 49 interactors |
STRINGi | 511145.b0623 |
Proteomic databases
jPOSTi | P0A972 |
PaxDbi | P0A972 |
PRIDEi | P0A972 |
Genome annotation databases
EnsemblBacteriai | AAC73724; AAC73724; b0623 BAA35266; BAA35266; BAA35266 |
GeneIDi | 52075941 947024 |
KEGGi | ecj:JW0618 eco:b0623 |
PATRICi | fig|1411691.4.peg.1645 |
Organism-specific databases
EchoBASEi | EB2096 |
Phylogenomic databases
eggNOGi | COG1278, Bacteria |
HOGENOMi | CLU_117621_2_1_6 |
InParanoidi | P0A972 |
PhylomeDBi | P0A972 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG12179-MONOMER |
Miscellaneous databases
PROi | PR:P0A972 |
Family and domain databases
CDDi | cd04458, CSP_CDS, 1 hit |
InterProi | View protein in InterPro IPR012156, Cold_shock_CspA IPR011129, CSD IPR019844, CSD_1 IPR002059, CSP_DNA-bd IPR012340, NA-bd_OB-fold |
Pfami | View protein in Pfam PF00313, CSD, 1 hit |
PIRSFi | PIRSF002599, Cold_shock_A, 1 hit |
PRINTSi | PR00050, COLDSHOCK |
SMARTi | View protein in SMART SM00357, CSP, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
PROSITEi | View protein in PROSITE PS00352, CSD_1, 1 hit PS51857, CSD_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CSPE_ECOLI | |
Accessioni | P0A972Primary (citable) accession number: P0A972 Secondary accession number(s): P36997, P77103, P80434 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 19, 2005 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 115 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |