UniProtKB - P0A937 (BAME_ECOLI)
Outer membrane protein assembly factor BamE
bamE
Functioni
GO - Molecular functioni
- identical protein binding Source: IntAct
- protein-macromolecule adaptor activity Source: EcoCyc
GO - Biological processi
- Gram-negative-bacterium-type cell outer membrane assembly Source: EcoCyc
- protein insertion into membrane Source: EcoCyc
- response to antibiotic Source: EcoCyc
Enzyme and pathway databases
BioCyci | EcoCyc:EG10952-MONOMER |
Protein family/group databases
TCDBi | 1.B.33.1.3, the outer membrane protein insertion porin (bam complex) (ompip) family |
Names & Taxonomyi
Protein namesi | Recommended name: Outer membrane protein assembly factor BamEUniRule annotation |
Gene namesi | Name:bamEUniRule annotation Synonyms:smpA Ordered Locus Names:b2617, JW2598 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Other locations
- Cell outer membrane UniRule annotation3 Publications; Lipid-anchor UniRule annotation2 Publications
Other locations
- Bam protein complex Source: EcoCyc
Keywords - Cellular componenti
Cell outer membrane, MembranePathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | UniRule annotationAdd BLAST | 19 | |
ChainiPRO_0000032810 | 20 – 113 | Outer membrane protein assembly factor BamEAdd BLAST | 94 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Lipidationi | 20 | N-palmitoyl cysteine1 Publication | 1 | |
Lipidationi | 20 | S-diacylglycerol cysteine1 Publication | 1 |
Keywords - PTMi
Lipoprotein, PalmitateProteomic databases
jPOSTi | P0A937 |
PaxDbi | P0A937 |
PRIDEi | P0A937 |
Interactioni
Subunit structurei
Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
Forms a subcomplex with BamC and BamD. Monomer in the periplasm, but is able to adopt a dimeric conformation in the cytoplasm (PubMed:21207987). The Bam complex has the shape of a hat, with the BamA beta-barrel crown in the outer membrane and the periplasmic brim formed by the BamA POTRA domains and the 4 lipoproteins (PubMed:27686148, PubMed:26900875, PubMed:26901871, PubMed:26744406). The intact Bam complex can have 2 BamE subunits (PubMed:27686148).
11 PublicationsBinary interactionsi
Hide detailsP0A937
With | #Exp. | IntAct |
---|---|---|
bamD [P0AC02] | 3 | EBI-6391574,EBI-1128087 |
itself | 14 | EBI-6391574,EBI-6391574 |
GO - Molecular functioni
- identical protein binding Source: IntAct
Protein-protein interaction databases
BioGRIDi | 4259570, 145 interactors 849957, 2 interactors |
ComplexPortali | CPX-1923, BAM complex |
DIPi | DIP-10895N |
IntActi | P0A937, 5 interactors |
MINTi | P0A937 |
STRINGi | 511145.b2617 |
Structurei
Secondary structure
3D structure databases
BMRBi | P0A937 |
SMRi | P0A937 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P0A937 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG2913, Bacteria |
HOGENOMi | CLU_083835_4_0_6 |
InParanoidi | P0A937 |
PhylomeDBi | P0A937 |
Family and domain databases
Gene3Di | 3.30.1450.10, 1 hit |
HAMAPi | MF_00925, OM_assembly_BamE, 1 hit |
InterProi | View protein in InterPro IPR026592, BamE IPR037873, BamE-like IPR007450, Lipoprotein_SmpA/OmlA |
PANTHERi | PTHR37482, PTHR37482, 1 hit |
Pfami | View protein in Pfam PF04355, SmpA_OmlA, 1 hit |
PROSITEi | View protein in PROSITE PS51257, PROKAR_LIPOPROTEIN, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
10 20 30 40 50
MRCKTLTAAA AVLLMLTAGC STLERVVYRP DINQGNYLTA NDVSKIRVGM
60 70 80 90 100
TQQQVAYALG TPLMSDPFGT NTWFYVFRQQ PGHEGVTQQT LTLTFNSSGV
110
LTNIDNKPAL SGN
Sequence cautioni
Mass spectrometryi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U36840 Genomic DNA Translation: AAA79787.1 U00096 Genomic DNA Translation: AAC75666.2 AP009048 Genomic DNA Translation: BAA16502.1 X52620 Genomic DNA Translation: CAA36847.1 Sequence problems. |
PIRi | S11646 T08630 |
RefSeqi | NP_417107.2, NC_000913.3 WP_001203437.1, NZ_STEB01000040.1 |
Genome annotation databases
EnsemblBacteriai | AAC75666; AAC75666; b2617 BAA16502; BAA16502; BAA16502 |
GeneIDi | 58463080 945583 |
KEGGi | ecj:JW2598 eco:b2617 |
PATRICi | fig|1411691.4.peg.4122 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U36840 Genomic DNA Translation: AAA79787.1 U00096 Genomic DNA Translation: AAC75666.2 AP009048 Genomic DNA Translation: BAA16502.1 X52620 Genomic DNA Translation: CAA36847.1 Sequence problems. |
PIRi | S11646 T08630 |
RefSeqi | NP_417107.2, NC_000913.3 WP_001203437.1, NZ_STEB01000040.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2KM7 | NMR | - | A | 20-113 | [»] | |
2KXX | NMR | - | A | 21-113 | [»] | |
2YH9 | X-ray | 1.80 | A/B/C | 34-113 | [»] | |
5AYW | X-ray | 3.56 | E | 20-113 | [»] | |
5D0O | X-ray | 2.90 | E | 1-113 | [»] | |
5D0Q | X-ray | 3.50 | E/I | 1-113 | [»] | |
5EKQ | X-ray | 3.39 | E | 20-113 | [»] | |
5LJO | electron microscopy | 4.90 | E | 24-110 | [»] | |
6LYQ | X-ray | 3.19 | E | 1-113 | [»] | |
6LYR | X-ray | 3.28 | E | 1-113 | [»] | |
6LYS | X-ray | 3.05 | E | 1-113 | [»] | |
6LYU | electron microscopy | 4.20 | E | 1-113 | [»] | |
6SN9 | electron microscopy | 9.80 | E | 24-110 | [»] | |
6V05 | electron microscopy | 4.10 | E | 1-113 | [»] | |
BMRBi | P0A937 | |||||
SMRi | P0A937 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4259570, 145 interactors 849957, 2 interactors |
ComplexPortali | CPX-1923, BAM complex |
DIPi | DIP-10895N |
IntActi | P0A937, 5 interactors |
MINTi | P0A937 |
STRINGi | 511145.b2617 |
Protein family/group databases
TCDBi | 1.B.33.1.3, the outer membrane protein insertion porin (bam complex) (ompip) family |
Proteomic databases
jPOSTi | P0A937 |
PaxDbi | P0A937 |
PRIDEi | P0A937 |
Genome annotation databases
EnsemblBacteriai | AAC75666; AAC75666; b2617 BAA16502; BAA16502; BAA16502 |
GeneIDi | 58463080 945583 |
KEGGi | ecj:JW2598 eco:b2617 |
PATRICi | fig|1411691.4.peg.4122 |
Organism-specific databases
EchoBASEi | EB0945 |
Phylogenomic databases
eggNOGi | COG2913, Bacteria |
HOGENOMi | CLU_083835_4_0_6 |
InParanoidi | P0A937 |
PhylomeDBi | P0A937 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10952-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P0A937 |
PROi | PR:P0A937 |
Family and domain databases
Gene3Di | 3.30.1450.10, 1 hit |
HAMAPi | MF_00925, OM_assembly_BamE, 1 hit |
InterProi | View protein in InterPro IPR026592, BamE IPR037873, BamE-like IPR007450, Lipoprotein_SmpA/OmlA |
PANTHERi | PTHR37482, PTHR37482, 1 hit |
Pfami | View protein in Pfam PF04355, SmpA_OmlA, 1 hit |
PROSITEi | View protein in PROSITE PS51257, PROKAR_LIPOPROTEIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BAME_ECOLI | |
Accessioni | P0A937Primary (citable) accession number: P0A937 Secondary accession number(s): P23089 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 19, 2005 |
Last sequence update: | July 19, 2005 | |
Last modified: | April 7, 2021 | |
This is version 124 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families