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Protein

MltA-interacting protein

Gene

mipA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May serve as a scaffold protein required for the formation of a complex with MrcB/PonB and MltA, this complex could play a role in enlargement and septation of the murein sacculus.

GO - Molecular functioni

  • protein binding, bridging Source: EcoCyc

GO - Biological processi

Enzyme and pathway databases

BioCyciEcoCyc:G6968-MONOMER
MetaCyc:G6968-MONOMER

Protein family/group databases

TCDBi9.B.99.1.2 the mipa-interacting protein (mipa) family

Names & Taxonomyi

Protein namesi
Recommended name:
MltA-interacting protein
Gene namesi
Name:mipA
Synonyms:yeaF
Ordered Locus Names:b1782, JW1771
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13492 mipA

Subcellular locationi

GO - Cellular componenti

  • cell outer membrane Source: EcoCyc

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 221 PublicationAdd BLAST22
ChainiPRO_000001909223 – 248MltA-interacting proteinAdd BLAST226

Proteomic databases

EPDiP0A908
PaxDbiP0A908
PRIDEiP0A908

Interactioni

Subunit structurei

Forms a trimeric complex with MrcB and MltA in vitro.

GO - Molecular functioni

Protein-protein interaction databases

BioGridi4260311, 187 interactors
IntActiP0A908, 4 interactors
STRINGi316385.ECDH10B_1920

Structurei

3D structure databases

ProteinModelPortaliP0A908
SMRiP0A908
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MipA/OmpV family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105GNX Bacteria
COG3713 LUCA
HOGENOMiHOG000121141
InParanoidiP0A908
KOiK07274
OMAiEVKDSPM
PhylomeDBiP0A908

Family and domain databases

InterProiView protein in InterPro
IPR010583 MipA
PANTHERiPTHR38776 PTHR38776, 1 hit
PfamiView protein in Pfam
PF06629 MipA, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A908-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTKLKLLALG VLIATSAGVA HAEGKFSLGA GVGVVEHPYK DYDTDVYPVP
60 70 80 90 100
VINYEGDNFW FRGLGGGYYL WNDATDKLSI TAYWSPLYFK AKDSGDHQMR
110 120 130 140 150
HLDDRKSTMM AGLSYAHFTQ YGYLRTTLAG DTLDNSNGIV WDMAWLYRYT
160 170 180 190 200
NGGLTVTPGI GVQWNSENQN EYYYGVSRKE SARSGLRGYN PNDSWSPYLE
210 220 230 240
LSASYNFLGD WSVYGTARYT RLSDEVTDSP MVDKSWTGLI STGITYKF
Length:248
Mass (Da):27,831
Last modified:July 19, 2005 - v1
Checksum:i6571B0D7A47A0525
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti34V → N AA sequence (PubMed:10037771).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74852.1
AP009048 Genomic DNA Translation: BAA15579.1
PIRiF64938
RefSeqiNP_416296.1, NC_000913.3
WP_000163771.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74852; AAC74852; b1782
BAA15579; BAA15579; BAA15579
GeneIDi946301
KEGGiecj:JW1771
eco:b1782
PATRICifig|1411691.4.peg.472

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC74852.1
AP009048 Genomic DNA Translation: BAA15579.1
PIRiF64938
RefSeqiNP_416296.1, NC_000913.3
WP_000163771.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliP0A908
SMRiP0A908
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260311, 187 interactors
IntActiP0A908, 4 interactors
STRINGi316385.ECDH10B_1920

Protein family/group databases

TCDBi9.B.99.1.2 the mipa-interacting protein (mipa) family

Proteomic databases

EPDiP0A908
PaxDbiP0A908
PRIDEiP0A908

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74852; AAC74852; b1782
BAA15579; BAA15579; BAA15579
GeneIDi946301
KEGGiecj:JW1771
eco:b1782
PATRICifig|1411691.4.peg.472

Organism-specific databases

EchoBASEiEB3265
EcoGeneiEG13492 mipA

Phylogenomic databases

eggNOGiENOG4105GNX Bacteria
COG3713 LUCA
HOGENOMiHOG000121141
InParanoidiP0A908
KOiK07274
OMAiEVKDSPM
PhylomeDBiP0A908

Enzyme and pathway databases

BioCyciEcoCyc:G6968-MONOMER
MetaCyc:G6968-MONOMER

Miscellaneous databases

PROiPR:P0A908

Family and domain databases

InterProiView protein in InterPro
IPR010583 MipA
PANTHERiPTHR38776 PTHR38776, 1 hit
PfamiView protein in Pfam
PF06629 MipA, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMIPA_ECOLI
AccessioniPrimary (citable) accession number: P0A908
Secondary accession number(s): O07962, P77486
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2005
Last sequence update: July 19, 2005
Last modified: October 10, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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