UniProtKB - P0A8Q6 (CLPS_ECOLI)
Protein
ATP-dependent Clp protease adapter protein ClpS
Gene
clpS
Organism
Escherichia coli (strain K12)
Status
Functioni
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.UniRule annotation1 Publication
GO - Molecular functioni
- chaperone binding Source: EcoCyc
GO - Biological processi
- protein catabolic process Source: InterPro
- proteolysis Source: UniProtKB-UniRule
- response to heat Source: EcoCyc
Enzyme and pathway databases
BioCyci | EcoCyc:G6463-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: ATP-dependent Clp protease adapter protein ClpSUniRule annotation |
Gene namesi | Name:clpSUniRule annotation Synonyms:yljA Ordered Locus Names:b0881, JW0865 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000215707 | 1 – 106 | ATP-dependent Clp protease adapter protein ClpSAdd BLAST | 106 |
Proteomic databases
jPOSTi | P0A8Q6 |
PaxDbi | P0A8Q6 |
PRIDEi | P0A8Q6 |
2D gel databases
SWISS-2DPAGEi | P0A8Q6 |
Interactioni
Subunit structurei
Binds to the N-terminal domain of the chaperone ClpA.
UniRule annotation2 PublicationsBinary interactionsi
Hide detailsGO - Molecular functioni
- chaperone binding Source: EcoCyc
Protein-protein interaction databases
BioGRIDi | 4261321, 77 interactors 852740, 2 interactors |
DIPi | DIP-35408N |
IntActi | P0A8Q6, 43 interactors |
MINTi | P0A8Q6 |
STRINGi | 511145.b0881 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P0A8Q6 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P0A8Q6 |
Family & Domainsi
Sequence similaritiesi
Belongs to the ClpS family.UniRule annotation
Phylogenomic databases
eggNOGi | COG2127, Bacteria |
HOGENOMi | CLU_134358_2_1_6 |
InParanoidi | P0A8Q6 |
PhylomeDBi | P0A8Q6 |
Family and domain databases
Gene3Di | 3.30.1390.10, 1 hit |
HAMAPi | MF_00302, ClpS, 1 hit |
InterProi | View protein in InterPro IPR022935, ClpS IPR003769, ClpS_core IPR014719, Ribosomal_L7/12_C/ClpS-like |
Pfami | View protein in Pfam PF02617, ClpS, 1 hit |
SUPFAMi | SSF54736, SSF54736, 1 hit |
i Sequence
Sequence statusi: Complete.
P0A8Q6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKTNDWLDF DQLAEEKVRD ALKPPSMYKV ILVNDDYTPM EFVIDVLQKF
60 70 80 90 100
FSYDVERATQ LMLAVHYQGK AICGVFTAEV AETKVAMVNK YARENEHPLL
CTLEKA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73968.1 AP009048 Genomic DNA Translation: BAA35600.1 |
PIRi | A64827 |
RefSeqi | NP_415402.1, NC_000913.3 WP_000520781.1, NZ_STEB01000006.1 |
Genome annotation databases
EnsemblBacteriai | AAC73968; AAC73968; b0881 BAA35600; BAA35600; BAA35600 |
GeneIDi | 52076193 948443 |
KEGGi | ecj:JW0865 eco:b0881 |
PATRICi | fig|1411691.4.peg.1396 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC73968.1 AP009048 Genomic DNA Translation: BAA35600.1 |
PIRi | A64827 |
RefSeqi | NP_415402.1, NC_000913.3 WP_000520781.1, NZ_STEB01000006.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1LZW | X-ray | 2.50 | A | 1-106 | [»] | |
1MBU | X-ray | 2.30 | C/D | 1-106 | [»] | |
1MBV | X-ray | 3.30 | B | 1-106 | [»] | |
1MBX | X-ray | 2.25 | C/D | 1-106 | [»] | |
1MG9 | X-ray | 2.30 | A | 1-106 | [»] | |
1R6O | X-ray | 2.25 | C/D | 1-106 | [»] | |
1R6Q | X-ray | 2.35 | C/D | 1-106 | [»] | |
2W9R | X-ray | 1.70 | A | 1-106 | [»] | |
2WA8 | X-ray | 2.15 | A/C | 1-106 | [»] | |
2WA9 | X-ray | 2.90 | A/B/C/D/E/F/G | 1-106 | [»] | |
3O1F | X-ray | 1.40 | A/B | 26-106 | [»] | |
3O2B | X-ray | 2.05 | A/C | 2-106 | [»] | |
3O2H | X-ray | 1.70 | A | 2-106 | [»] | |
3O2O | X-ray | 2.90 | A/B/C/D/E/F/G/H | 22-106 | [»] | |
SMRi | P0A8Q6 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 4261321, 77 interactors 852740, 2 interactors |
DIPi | DIP-35408N |
IntActi | P0A8Q6, 43 interactors |
MINTi | P0A8Q6 |
STRINGi | 511145.b0881 |
2D gel databases
SWISS-2DPAGEi | P0A8Q6 |
Proteomic databases
jPOSTi | P0A8Q6 |
PaxDbi | P0A8Q6 |
PRIDEi | P0A8Q6 |
Genome annotation databases
EnsemblBacteriai | AAC73968; AAC73968; b0881 BAA35600; BAA35600; BAA35600 |
GeneIDi | 52076193 948443 |
KEGGi | ecj:JW0865 eco:b0881 |
PATRICi | fig|1411691.4.peg.1396 |
Organism-specific databases
EchoBASEi | EB3992 |
Phylogenomic databases
eggNOGi | COG2127, Bacteria |
HOGENOMi | CLU_134358_2_1_6 |
InParanoidi | P0A8Q6 |
PhylomeDBi | P0A8Q6 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6463-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P0A8Q6 |
PROi | PR:P0A8Q6 |
Family and domain databases
Gene3Di | 3.30.1390.10, 1 hit |
HAMAPi | MF_00302, ClpS, 1 hit |
InterProi | View protein in InterPro IPR022935, ClpS IPR003769, ClpS_core IPR014719, Ribosomal_L7/12_C/ClpS-like |
Pfami | View protein in Pfam PF02617, ClpS, 1 hit |
SUPFAMi | SSF54736, SSF54736, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CLPS_ECOLI | |
Accessioni | P0A8Q6Primary (citable) accession number: P0A8Q6 Secondary accession number(s): P75832 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2005 |
Last sequence update: | June 7, 2005 | |
Last modified: | December 2, 2020 | |
This is version 115 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families