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UniProtKB - P0A8C8 (YIDD_ECOLI)
Protein
Putative membrane protein insertion efficiency factor
Gene
yidD
Organism
Escherichia coli (strain K12)
Status
Functioni
Could be involved in insertion of integral membrane proteins into the membrane.
UniRule annotation1 PublicationGO - Molecular functioni
- membrane insertase activity Source: EcoCyc
GO - Biological processi
- protein insertion into membrane Source: EcoCyc
Enzyme and pathway databases
BioCyci | EcoCyc:MONOMER0-2692 |
Names & Taxonomyi
Protein namesi | Recommended name: Putative membrane protein insertion efficiency factorUniRule annotation |
Gene namesi | Name:yidDUniRule annotation Ordered Locus Names:b4557, JW3682 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane UniRule annotation1 Publication; Peripheral membrane protein UniRule annotation1 Publication; Cytoplasmic side UniRule annotation1 Publication
Note: Associated with the inner membrane via a putative N-terminal amphipathic helix.
Plasma Membrane
- integral component of plasma membrane Source: EcoCyc
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePathology & Biotechi
Disruption phenotypei
Cells lacking this gene are viable with no apparent phenotype, but they are affected in the insertion and processing of three YidC-dependent inner membrane proteins.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000171821 | 1 – 85 | Putative membrane protein insertion efficiency factorAdd BLAST | 85 |
Proteomic databases
PaxDbi | P0A8C8 |
PRIDEi | P0A8C8 |
Structurei
3D structure databases
AlphaFoldDBi | P0A8C8 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Sequence similaritiesi
Belongs to the UPF0161 family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0759, Bacteria |
HOGENOMi | CLU_144811_5_2_6 |
InParanoidi | P0A8C8 |
OMAi | QPTCSHY |
PhylomeDBi | P0A8C8 |
Family and domain databases
HAMAPi | MF_00386, UPF0161_YidD, 1 hit |
InterProi | View protein in InterPro IPR002696, Membr_insert_effic_factor |
PANTHERi | PTHR33383, PTHR33383, 1 hit |
Pfami | View protein in Pfam PF01809, YidD, 1 hit |
SMARTi | View protein in SMART SM01234, Haemolytic, 1 hit |
TIGRFAMsi | TIGR00278, TIGR00278, 1 hit |
i Sequence
Sequence statusi: Complete.
P0A8C8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPPLSPGSR VLIALIRVYQ RLISPLLGPH CRFTPTCSSY GIEALRRFGV
60 70 80
IKGSWLTVKR VLKCHPLHPG GDDPVPPGPF DTREH
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M11056 Genomic DNA No translation available. U00096 Genomic DNA Translation: ABD18707.1 AP009048 Genomic DNA Translation: BAE77589.1 |
RefSeqi | WP_001307474.1, NZ_STEB01000015.1 YP_588472.1, NC_000913.3 |
Genome annotation databases
EnsemblBacteriai | ABD18707; ABD18707; b4557 BAE77589; BAE77589; BAE77589 |
GeneIDi | 1450303 64726507 67464395 |
KEGGi | ecj:JW3682 eco:b4557 |
PATRICi | fig|83333.103.peg.3 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M11056 Genomic DNA No translation available. U00096 Genomic DNA Translation: ABD18707.1 AP009048 Genomic DNA Translation: BAE77589.1 |
RefSeqi | WP_001307474.1, NZ_STEB01000015.1 YP_588472.1, NC_000913.3 |
3D structure databases
AlphaFoldDBi | P0A8C8 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 511145.b4557 |
Proteomic databases
PaxDbi | P0A8C8 |
PRIDEi | P0A8C8 |
Genome annotation databases
EnsemblBacteriai | ABD18707; ABD18707; b4557 BAE77589; BAE77589; BAE77589 |
GeneIDi | 1450303 64726507 67464395 |
KEGGi | ecj:JW3682 eco:b4557 |
PATRICi | fig|83333.103.peg.3 |
Organism-specific databases
EchoBASEi | EB1324 |
Phylogenomic databases
eggNOGi | COG0759, Bacteria |
HOGENOMi | CLU_144811_5_2_6 |
InParanoidi | P0A8C8 |
OMAi | QPTCSHY |
PhylomeDBi | P0A8C8 |
Enzyme and pathway databases
BioCyci | EcoCyc:MONOMER0-2692 |
Miscellaneous databases
PROi | PR:P0A8C8 |
Family and domain databases
HAMAPi | MF_00386, UPF0161_YidD, 1 hit |
InterProi | View protein in InterPro IPR002696, Membr_insert_effic_factor |
PANTHERi | PTHR33383, PTHR33383, 1 hit |
Pfami | View protein in Pfam PF01809, YidD, 1 hit |
SMARTi | View protein in SMART SM01234, Haemolytic, 1 hit |
TIGRFAMsi | TIGR00278, TIGR00278, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YIDD_ECOLI | |
Accessioni | P0A8C8Primary (citable) accession number: P0A8C8 Secondary accession number(s): P22847, Q2EET9, Q2M817 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2005 |
Last sequence update: | June 7, 2005 | |
Last modified: | May 25, 2022 | |
This is version 108 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families