UniProtKB - P0A8A8 (RIMP_ECOLI)
Protein
Ribosome maturation factor RimP
Gene
rimP
Organism
Escherichia coli (strain K12)
Status
Functioni
Required for maturation of 30S ribosomal subunits, probably at a late stage of ribosomal protein binding, while Era is associated and after RimM (PubMed:20188109).2 Publications
GO - Biological processi
- ribosomal small subunit assembly Source: EcoCyc
- ribosomal small subunit biogenesis Source: EcoliWiki
- translation Source: EcoliWiki
Keywordsi
Biological process | Ribosome biogenesis |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11179-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Ribosome maturation factor RimP |
Gene namesi | Name:rimP Synonyms:yhbC Ordered Locus Names:b3170, JW5533 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm Curated
Cytosol
- cytosol Source: EcoCyc
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Disruption phenotypei
Cells lacking this gene show a reduced growth rate, especially at high temperatures. They show a reduced amount of 70S ribosomes engaged in translation and a corresponding increase in the amount of free ribosomal subunits.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000181869 | 1 – 150 | Ribosome maturation factor RimPAdd BLAST | 150 |
Proteomic databases
jPOSTi | P0A8A8 |
PaxDbi | P0A8A8 |
PRIDEi | P0A8A8 |
Interactioni
Subunit structurei
Associates with free 30S subunits, but not with free 50S subunits or with mature ribosomes.
Binary interactionsi
Hide detailsProtein-protein interaction databases
BioGRIDi | 4260791, 67 interactors 851993, 3 interactors |
DIPi | DIP-47892N |
IntActi | P0A8A8, 7 interactors |
STRINGi | 511145.b3170 |
Family & Domainsi
Sequence similaritiesi
Belongs to the RimP family.Curated
Phylogenomic databases
eggNOGi | COG0779, Bacteria |
HOGENOMi | CLU_070525_1_1_6 |
InParanoidi | P0A8A8 |
PhylomeDBi | P0A8A8 |
Family and domain databases
CDDi | cd01734, YlxS_C, 1 hit |
Gene3Di | 3.30.300.70, 1 hit |
HAMAPi | MF_01077, RimP, 1 hit |
InterProi | View protein in InterPro IPR003728, Ribosome_maturation_RimP IPR028998, RimP_C IPR036847, RimP_C_sf IPR028989, RimP_N IPR035956, RimP_N_sf |
PANTHERi | PTHR33867, PTHR33867, 1 hit |
Pfami | View protein in Pfam PF02576, DUF150, 1 hit PF17384, DUF150_C, 1 hit |
SUPFAMi | SSF74942, SSF74942, 1 hit SSF75420, SSF75420, 1 hit |
i Sequence
Sequence statusi: Complete.
P0A8A8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTLEQKLTE MITAPVEALG FELVGIEFIR GRTSTLRIYI DSEDGINVDD
60 70 80 90 100
CADVSHQVSA VLDVEDPITV AYNLEVSSPG LDRPLFTAEH YARFVGEEVT
110 120 130 140 150
LVLRMAVQNR RKWQGVIKAV DGEMITVTVE GKDEVFALSN IQKANLVPHF
Sequence cautioni
The sequence AAA57973 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CAA25199 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 9 | T → A in CAA25199 (PubMed:6326058).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X00513 Genomic DNA Translation: CAA25199.1 Frameshift. U18997 Genomic DNA Translation: AAA57973.1 Different initiation. U00096 Genomic DNA Translation: AAC76204.4 AP009048 Genomic DNA Translation: BAE77216.1 |
PIRi | F65107, WMECN5 |
RefSeqi | NP_417639.6, NC_000913.3 WP_001300397.1, NZ_STEB01000012.1 |
Genome annotation databases
EnsemblBacteriai | AAC76204; AAC76204; b3170 BAE77216; BAE77216; BAE77216 |
GeneIDi | 58462838 947680 |
KEGGi | ecj:JW5533 eco:b3170 |
PATRICi | fig|1411691.4.peg.3560 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X00513 Genomic DNA Translation: CAA25199.1 Frameshift. U18997 Genomic DNA Translation: AAA57973.1 Different initiation. U00096 Genomic DNA Translation: AAC76204.4 AP009048 Genomic DNA Translation: BAE77216.1 |
PIRi | F65107, WMECN5 |
RefSeqi | NP_417639.6, NC_000913.3 WP_001300397.1, NZ_STEB01000012.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260791, 67 interactors 851993, 3 interactors |
DIPi | DIP-47892N |
IntActi | P0A8A8, 7 interactors |
STRINGi | 511145.b3170 |
Proteomic databases
jPOSTi | P0A8A8 |
PaxDbi | P0A8A8 |
PRIDEi | P0A8A8 |
Genome annotation databases
EnsemblBacteriai | AAC76204; AAC76204; b3170 BAE77216; BAE77216; BAE77216 |
GeneIDi | 58462838 947680 |
KEGGi | ecj:JW5533 eco:b3170 |
PATRICi | fig|1411691.4.peg.3560 |
Organism-specific databases
EchoBASEi | EB1166 |
Phylogenomic databases
eggNOGi | COG0779, Bacteria |
HOGENOMi | CLU_070525_1_1_6 |
InParanoidi | P0A8A8 |
PhylomeDBi | P0A8A8 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11179-MONOMER |
Miscellaneous databases
PROi | PR:P0A8A8 |
Family and domain databases
CDDi | cd01734, YlxS_C, 1 hit |
Gene3Di | 3.30.300.70, 1 hit |
HAMAPi | MF_01077, RimP, 1 hit |
InterProi | View protein in InterPro IPR003728, Ribosome_maturation_RimP IPR028998, RimP_C IPR036847, RimP_C_sf IPR028989, RimP_N IPR035956, RimP_N_sf |
PANTHERi | PTHR33867, PTHR33867, 1 hit |
Pfami | View protein in Pfam PF02576, DUF150, 1 hit PF17384, DUF150_C, 1 hit |
SUPFAMi | SSF74942, SSF74942, 1 hit SSF75420, SSF75420, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RIMP_ECOLI | |
Accessioni | P0A8A8Primary (citable) accession number: P0A8A8 Secondary accession number(s): P03843, Q2M940, Q8X9M1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 21, 1986 |
Last sequence update: | November 24, 2009 | |
Last modified: | February 10, 2021 | |
This is version 115 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families