UniProtKB - P0A843 (TATE_ECOLI)
Protein
Sec-independent protein translocase protein TatE
Gene
tatE
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.UniRule annotation1 Publication
GO - Molecular functioni
- protein transmembrane transporter activity Source: EcoliWiki
GO - Biological processi
- protein transport by the Tat complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, Translocation, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11305-MONOMER MetaCyc:EG11305-MONOMER |
Protein family/group databases
TCDBi | 2.A.64.1.1, the twin arginine targeting (tat) family |
Names & Taxonomyi
Protein namesi | Recommended name: Sec-independent protein translocase protein TatE |
Gene namesi | Name:tatEUniRule annotation Synonyms:ybeC Ordered Locus Names:b0627, JW0622 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation
Plasma Membrane
- integral component of plasma membrane Source: EcoCyc
- plasma membrane Source: EcoCyc
- TAT protein transport complex Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 4 – 21 | HelicalUniRule annotationAdd BLAST | 18 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePathology & Biotechi
Disruption phenotypei
Disruption of tatE affects the correct localization of multiple enzymes whose precursors bear twin arginine transfer peptides. Export is completely blocked when both tatA and tatE are inactivated.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000097973 | 1 – 67 | Sec-independent protein translocase protein TatEAdd BLAST | 67 |
Proteomic databases
PaxDbi | P0A843 |
PRIDEi | P0A843 |
Expressioni
Inductioni
Constitutively expressed.1 Publication
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260637, 293 interactors |
ComplexPortali | CPX-3445, Twin-arginine translocation complex |
IntActi | P0A843, 56 interactors |
STRINGi | 511145.b0627 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG1826, Bacteria |
HOGENOMi | CLU_086034_5_3_6 |
InParanoidi | P0A843 |
Family and domain databases
HAMAPi | MF_00236, TatA_E, 1 hit MF_00903, TatE, 1 hit |
InterProi | View protein in InterPro IPR003369, TatA/B/E IPR006312, TatA/E IPR024905, TatE |
Pfami | View protein in Pfam PF02416, TatA_B_E, 1 hit |
TIGRFAMsi | TIGR01411, tatAE, 1 hit |
i Sequence
Sequence statusi: Complete.
P0A843-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGEISITKLL VVAALVVLLF GTKKLRTLGG DLGAAIKGFK KAMNDDDAAA
60
KKGADVDLQA EKLSHKE
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 44 | N → I in AAA24073 (PubMed:1577793).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M82805 Genomic DNA Translation: AAA24073.1 U82598 Genomic DNA Translation: AAB40827.1 U00096 Genomic DNA Translation: AAC73728.1 AP009048 Genomic DNA Translation: BAA35270.1 |
PIRi | JN0256 |
RefSeqi | NP_415160.1, NC_000913.3 WP_000503931.1, NZ_STEB01000031.1 |
Genome annotation databases
EnsemblBacteriai | AAC73728; AAC73728; b0627 BAA35270; BAA35270; BAA35270 |
GeneIDi | 58462990 945228 |
KEGGi | ecj:JW0622 eco:b0627 |
PATRICi | fig|1411691.4.peg.1641 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M82805 Genomic DNA Translation: AAA24073.1 U82598 Genomic DNA Translation: AAB40827.1 U00096 Genomic DNA Translation: AAC73728.1 AP009048 Genomic DNA Translation: BAA35270.1 |
PIRi | JN0256 |
RefSeqi | NP_415160.1, NC_000913.3 WP_000503931.1, NZ_STEB01000031.1 |
3D structure databases
SMRi | P0A843 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4260637, 293 interactors |
ComplexPortali | CPX-3445, Twin-arginine translocation complex |
IntActi | P0A843, 56 interactors |
STRINGi | 511145.b0627 |
Protein family/group databases
TCDBi | 2.A.64.1.1, the twin arginine targeting (tat) family |
Proteomic databases
PaxDbi | P0A843 |
PRIDEi | P0A843 |
Genome annotation databases
EnsemblBacteriai | AAC73728; AAC73728; b0627 BAA35270; BAA35270; BAA35270 |
GeneIDi | 58462990 945228 |
KEGGi | ecj:JW0622 eco:b0627 |
PATRICi | fig|1411691.4.peg.1641 |
Organism-specific databases
EchoBASEi | EB1282 |
Phylogenomic databases
eggNOGi | COG1826, Bacteria |
HOGENOMi | CLU_086034_5_3_6 |
InParanoidi | P0A843 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11305-MONOMER MetaCyc:EG11305-MONOMER |
Miscellaneous databases
PROi | PR:P0A843 |
Family and domain databases
HAMAPi | MF_00236, TatA_E, 1 hit MF_00903, TatE, 1 hit |
InterProi | View protein in InterPro IPR003369, TatA/B/E IPR006312, TatA/E IPR024905, TatE |
Pfami | View protein in Pfam PF02416, TatA_B_E, 1 hit |
TIGRFAMsi | TIGR01411, tatAE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TATE_ECOLI | |
Accessioni | P0A843Primary (citable) accession number: P0A843 Secondary accession number(s): P25895, P77420 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2005 |
Last sequence update: | June 7, 2005 | |
Last modified: | February 10, 2021 | |
This is version 110 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families