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Protein

Sec-independent protein translocase protein TatE

Gene

tatE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA.UniRule annotation1 Publication

GO - Molecular functioni

  • protein transporter activity Source: EcoCyc

GO - Biological processi

Keywordsi

Biological processProtein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11305-MONOMER
MetaCyc:EG11305-MONOMER

Protein family/group databases

TCDBi2.A.64.1.1 the twin arginine targeting (tat) family

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatE
Gene namesi
Name:tatEUniRule annotation
Synonyms:ybeC
Ordered Locus Names:b0627, JW0622
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11305 tatE

Subcellular locationi

  • Cell inner membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 21HelicalUniRule annotationAdd BLAST18

GO - Cellular componenti

  • integral component of plasma membrane Source: EcoCyc
  • plasma membrane Source: EcoCyc
  • TAT protein transport complex Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Disruption of tatE affects the correct localization of multiple enzymes whose precursors bear twin arginine transfer peptides. Export is completely blocked when both tatA and tatE are inactivated.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000979731 – 67Sec-independent protein translocase protein TatEAdd BLAST67

Proteomic databases

PaxDbiP0A843
PRIDEiP0A843

Expressioni

Inductioni

Constitutively expressed.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260637, 293 interactors
IntActiP0A843, 56 interactors
STRINGi316385.ECDH10B_0696

Structurei

3D structure databases

ProteinModelPortaliP0A843
SMRiP0A843
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TatA/E family. TatE subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410607N Bacteria
COG1826 LUCA
HOGENOMiHOG000245363
InParanoidiP0A843
KOiK03425
OMAiGLSIWHI

Family and domain databases

HAMAPiMF_00236 TatA_E, 1 hit
MF_00903 TatE, 1 hit
InterProiView protein in InterPro
IPR003369 TatA/B/E
IPR006312 TatA/E
IPR024905 TatE
PfamiView protein in Pfam
PF02416 MttA_Hcf106, 1 hit
TIGRFAMsiTIGR01411 tatAE, 1 hit

Sequencei

Sequence statusi: Complete.

P0A843-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEISITKLL VVAALVVLLF GTKKLRTLGG DLGAAIKGFK KAMNDDDAAA
60
KKGADVDLQA EKLSHKE
Length:67
Mass (Da):7,024
Last modified:June 7, 2005 - v1
Checksum:iFA880C6DECE248A3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti44N → I in AAA24073 (PubMed:1577793).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M82805 Genomic DNA Translation: AAA24073.1
U82598 Genomic DNA Translation: AAB40827.1
U00096 Genomic DNA Translation: AAC73728.1
AP009048 Genomic DNA Translation: BAA35270.1
PIRiJN0256
RefSeqiNP_415160.1, NC_000913.3
WP_000503931.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73728; AAC73728; b0627
BAA35270; BAA35270; BAA35270
GeneIDi945228
KEGGiecj:JW0622
eco:b0627
PATRICifig|1411691.4.peg.1641

Similar proteinsi

Entry informationi

Entry nameiTATE_ECOLI
AccessioniPrimary (citable) accession number: P0A843
Secondary accession number(s): P25895, P77420
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: July 18, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

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