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Protein

DNA repair protein RecO

Gene

recO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in DNA repair and RecF pathway recombination.

GO - Biological processi

  • DNA recombination Source: UniProtKB-UniRule
  • DNA repair Source: UniProtKB-UniRule
  • response to radiation Source: EcoCyc

Keywordsi

Biological processDNA damage, DNA recombination, DNA repair

Enzyme and pathway databases

BioCyciEcoCyc:EG10832-MONOMER
MetaCyc:EG10832-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA repair protein RecO
Alternative name(s):
Recombination protein O
Gene namesi
Name:recO
Ordered Locus Names:b2565, JW2549
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10832 recO

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002049491 – 242DNA repair protein RecOAdd BLAST242

Proteomic databases

PaxDbiP0A7H3
PRIDEiP0A7H3

Expressioni

Inductioni

Encoded in the rnc-era-recO operon.

Interactioni

Subunit structurei

Monomer.1 Publication

Protein-protein interaction databases

BioGridi4259430, 175 interactors
DIPiDIP-48093N
IntActiP0A7H3, 8 interactors
STRINGi316385.ECDH10B_2733

Structurei

Secondary structure

1242
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP0A7H3
SMRiP0A7H3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecO family.Curated

Phylogenomic databases

eggNOGiENOG41071DT Bacteria
COG1381 LUCA
HOGENOMiHOG000245560
InParanoidiP0A7H3
KOiK03584
PhylomeDBiP0A7H3

Family and domain databases

HAMAPiMF_00201 RecO, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR022572 DNA_rep/recomb_RecO_N
IPR012340 NA-bd_OB-fold
IPR003717 RecO
PANTHERiPTHR33991 PTHR33991, 1 hit
PfamiView protein in Pfam
PF02565 RecO_C, 1 hit
PF11967 RecO_N, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF57863 SSF57863, 1 hit
TIGRFAMsiTIGR00613 reco, 1 hit

Sequencei

Sequence statusi: Complete.

P0A7H3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGWQRAFVL HSRPWSETSL MLDVFTEESG RVRLVAKGAR SKRSTLKGAL
60 70 80 90 100
QPFTPLLLRF GGRGEVKTLR SAEAVSLALP LSGITLYSGL YINELLSRVL
110 120 130 140 150
EYETRFSELF FDYLHCIQSL AGVTGTPEPA LRRFELALLG HLGYGVNFTH
160 170 180 190 200
CAGSGEPVDD TMTYRYREEK GFIASVVIDN KTFTGRQLKA LNAREFPDAD
210 220 230 240
TLRAAKRFTR MALKPYLGGK PLKSRELFRQ FMPKRTVKTH YE
Length:242
Mass (Da):27,391
Last modified:June 7, 2005 - v1
Checksum:iD21C242C2F842D74
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26416 Genomic DNA Translation: AAA21842.1
M27251 Genomic DNA Translation: AAA24515.1
D64044 Genomic DNA Translation: BAA10912.1
M76470 Genomic DNA Translation: AAA21844.1
U36841 Genomic DNA Translation: AAA79827.1
U00096 Genomic DNA Translation: AAC75618.1
AP009048 Genomic DNA Translation: BAE76741.1
M74526 Genomic DNA No translation available.
PIRiJS0116 BVECRO
RefSeqiNP_417060.1, NC_000913.3
WP_000399404.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75618; AAC75618; b2565
BAE76741; BAE76741; BAE76741
GeneIDi947038
KEGGiecj:JW2549
eco:b2565
PATRICifig|1411691.4.peg.4169

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M26416 Genomic DNA Translation: AAA21842.1
M27251 Genomic DNA Translation: AAA24515.1
D64044 Genomic DNA Translation: BAA10912.1
M76470 Genomic DNA Translation: AAA21844.1
U36841 Genomic DNA Translation: AAA79827.1
U00096 Genomic DNA Translation: AAC75618.1
AP009048 Genomic DNA Translation: BAE76741.1
M74526 Genomic DNA No translation available.
PIRiJS0116 BVECRO
RefSeqiNP_417060.1, NC_000913.3
WP_000399404.1, NZ_LN832404.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3Q8DX-ray2.30A/B1-242[»]
ProteinModelPortaliP0A7H3
SMRiP0A7H3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259430, 175 interactors
DIPiDIP-48093N
IntActiP0A7H3, 8 interactors
STRINGi316385.ECDH10B_2733

Proteomic databases

PaxDbiP0A7H3
PRIDEiP0A7H3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75618; AAC75618; b2565
BAE76741; BAE76741; BAE76741
GeneIDi947038
KEGGiecj:JW2549
eco:b2565
PATRICifig|1411691.4.peg.4169

Organism-specific databases

EchoBASEiEB0825
EcoGeneiEG10832 recO

Phylogenomic databases

eggNOGiENOG41071DT Bacteria
COG1381 LUCA
HOGENOMiHOG000245560
InParanoidiP0A7H3
KOiK03584
PhylomeDBiP0A7H3

Enzyme and pathway databases

BioCyciEcoCyc:EG10832-MONOMER
MetaCyc:EG10832-MONOMER

Miscellaneous databases

PROiPR:P0A7H3

Family and domain databases

HAMAPiMF_00201 RecO, 1 hit
InterProiView protein in InterPro
IPR037278 ARFGAP/RecO
IPR022572 DNA_rep/recomb_RecO_N
IPR012340 NA-bd_OB-fold
IPR003717 RecO
PANTHERiPTHR33991 PTHR33991, 1 hit
PfamiView protein in Pfam
PF02565 RecO_C, 1 hit
PF11967 RecO_N, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
SSF57863 SSF57863, 1 hit
TIGRFAMsiTIGR00613 reco, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRECO_ECOLI
AccessioniPrimary (citable) accession number: P0A7H3
Secondary accession number(s): P15027, P76589, Q2MAG5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: November 7, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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