Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - P0A786 (PYRB_ECOLI)

Protein

Aspartate carbamoyltransferase catalytic subunit

Gene

pyrB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: UMP biosynthesis via de novo pathway

This protein is involved in step 2 of the subpathway that synthesizes (S)-dihydroorotate from bicarbonate.
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Carbamoyl-phosphate synthase large chain (carB), Carbamoyl-phosphate synthase small chain (carA)
  2. Aspartate carbamoyltransferase catalytic subunit (pyrB)
  3. Dihydroorotase (pyrC)
This subpathway is part of the pathway UMP biosynthesis via de novo pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes (S)-dihydroorotate from bicarbonate, the pathway UMP biosynthesis via de novo pathway and in Pyrimidine metabolism.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • amino acid binding Source: InterPro
  • aspartate carbamoyltransferase activity Source: GO_Central
  • identical protein binding Source: IntAct
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processPyrimidine biosynthesis

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:ASPCARBCAT-MONOMER
MetaCyc:ASPCARBCAT-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.1.3.2 2026

SABIO-RK: Biochemical Reaction Kinetics Database

More...SABIO-RKi		P0A786

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi
UPA00070;UER00116

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Aspartate carbamoyltransferase catalytic subunit (EC:2.1.3.2)
Alternative name(s):
Aspartate transcarbamylase
Short name:
ATCase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pyrB
Ordered Locus Names:b4245, JW4204
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...EcoGenei		EG10805 pyrB

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • cytosol Source: EcoCyc
View the complete GO annotation on QuickGO ...

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved4 Publications
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001131282 – 311Aspartate carbamoyltransferase catalytic subunitAdd BLAST310

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P0A786

PRoteomics IDEntifications database

More...PRIDEi		P0A786

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...SWISS-2DPAGEi		P0A786

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterododecamer (2C3:3R2) of six catalytic PyrB chains organized as two trimers (C3), and six regulatory PyrI chains organized as three dimers (R2).1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		4260722, 54 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-3091 Aspartate carbamoyltransferase complex

Database of interacting proteins

More...DIPi		DIP-35089N

Protein interaction database and analysis system

More...IntActi		P0A786, 3 interactors

Molecular INTeraction database

More...MINTi		P0A786

STRING: functional protein association networks

More...STRINGi		316385.ECDH10B_4440

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1311
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		P0A786

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P0A786

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P0A786

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATCase/OTCase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG4105CXT Bacteria
COG0540 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000022685

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P0A786

KEGG Orthology (KO)

More...KOi		K00609

Database for complete collections of gene phylogenies

More...PhylomeDBi		P0A786

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.50.1370, 2 hits

HAMAP database of protein families

More...HAMAPi		MF_00001 Asp_carb_tr, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006132 Asp/Orn_carbamoyltranf_P-bd
IPR006130 Asp/Orn_carbamoylTrfase
IPR036901 Asp/Orn_carbamoylTrfase_sf
IPR002082 Asp_carbamoyltransf
IPR006131 Asp_carbamoyltransf_Asp/Orn-bd

The PANTHER Classification System

More...PANTHERi		PTHR11405:SF16 PTHR11405:SF16, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00185 OTCace, 1 hit
PF02729 OTCace_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00100 AOTCASE
PR00101 ATCASE

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF53671 SSF53671, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00670 asp_carb_tr, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00097 CARBAMOYLTRANSFERASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P0A786-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANPLYQKHI ISINDLSRDD LNLVLATAAK LKANPQPELL KHKVIASCFF 
        60         70         80         90        100
EASTRTRLSF ETSMHRLGAS VVGFSDSANT SLGKKGETLA DTISVISTYV 
       110        120        130        140        150
DAIVMRHPQE GAARLATEFS GNVPVLNAGD GSNQHPTQTL LDLFTIQETQ 
       160        170        180        190        200
GRLDNLHVAM VGDLKYGRTV HSLTQALAKF DGNRFYFIAP DALAMPQYIL 
       210        220        230        240        250
DMLDEKGIAW SLHSSIEEVM AEVDILYMTR VQKERLDPSE YANVKAQFVL 
       260        270        280        290        300
RASDLHNAKA NMKVLHPLPR VDEIATDVDK TPHAWYFQQA GNGIFARQAL 
       310 
LALVLNRDLV L
Length:311
Mass (Da):34,427
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCC2F5ACBD73E0E3E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti61E → Q in AAA24474 (PubMed:6302686).Curated1
Sequence conflicti61E → Q AA sequence (PubMed:6341995).Curated1
Sequence conflicti87E → Q AA sequence (PubMed:6341995).Curated1
Sequence conflicti91D → N AA sequence (PubMed:6341995).Curated1
Sequence conflicti130D → N AA sequence (PubMed:6341995).Curated1
Sequence conflicti150Q → E in AAA24476 (PubMed:6364131).Curated1
Sequence conflicti196P → R in AAA97142 (PubMed:7610040).Curated1
Sequence conflicti221A → V in AAA24474 (PubMed:6302686).Curated1
Sequence conflicti221A → V AA sequence (PubMed:6341995).Curated1
Sequence conflicti257N → D AA sequence (PubMed:6341995).Curated1
Sequence conflicti260 – 262ANM → MNA AA sequence (PubMed:6341995).Curated3
Sequence conflicti297R → L in AAA24474 (PubMed:6302686).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
J01670 Genomic DNA Translation: AAA24474.1
K01472 Genomic DNA Translation: AAA24476.1
U14003 Genomic DNA Translation: AAA97142.1
U00096 Genomic DNA Translation: AAC77202.1
AP009048 Genomic DNA Translation: BAE78244.1
M10743 Genomic DNA Translation: AAA24479.1
M60508 Genomic DNA Translation: AAA24481.1

Protein sequence database of the Protein Information Resource

More...PIRi		H65236 DTECC

NCBI Reference Sequences

More...RefSeqi		NP_418666.1, NC_000913.3
WP_000013046.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC77202; AAC77202; b4245
BAE78244; BAE78244; BAE78244

Database of genes from NCBI RefSeq genomes

More...GeneIDi		948767

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW4204
eco:b4245

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.2456

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
J01670 Genomic DNA Translation: AAA24474.1
K01472 Genomic DNA Translation: AAA24476.1
U14003 Genomic DNA Translation: AAA97142.1
U00096 Genomic DNA Translation: AAC77202.1
AP009048 Genomic DNA Translation: BAE78244.1
M10743 Genomic DNA Translation: AAA24479.1
M60508 Genomic DNA Translation: AAA24481.1
PIRiH65236 DTECC
RefSeqiNP_418666.1, NC_000913.3
WP_000013046.1, NZ_LN832404.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1ACMX-ray2.80A/C2-311[»]
1AT1X-ray2.80A/C2-311[»]
1D09X-ray2.10A/C2-311[»]
1EKXX-ray1.95A/B/C1-311[»]
1EZZX-ray2.70A/C2-311[»]
1F1BX-ray2.30A/C2-311[»]
1I5OX-ray2.80A/C2-311[»]
1NBEX-ray2.60A/C2-311[»]
1Q95X-ray2.46A/B/C/D/E/F2-311[»]
1R0BX-ray2.90A/B/C/D/E/F2-311[»]
1R0CX-ray2.37A/G2-311[»]
1RAAX-ray2.50A/C2-311[»]
1RABX-ray2.50A/C2-311[»]
1RACX-ray2.50A/C2-311[»]
1RADX-ray2.50A/C2-311[»]
1RAEX-ray2.50A/C2-311[»]
1RAFX-ray2.50A/C2-311[»]
1RAGX-ray2.50A/C2-311[»]
1RAHX-ray2.50A/C2-311[»]
1RAIX-ray2.50A/C2-311[»]
1SKUX-ray2.60A/C2-311[»]
1TTHX-ray2.80A/C2-311[»]
1TU0X-ray2.55A/C2-311[»]
1TUGX-ray2.10A/C2-311[»]
1XJWX-ray2.71A/C2-311[»]
1ZA1X-ray2.20A/C2-311[»]
1ZA2X-ray2.50A/C2-311[»]
2A0FX-ray2.90A/C2-311[»]
2AIRX-ray2.00A/G2-311[»]
2AT1X-ray2.80A/C2-311[»]
2ATCX-ray3.00A2-311[»]
2FZCX-ray2.10A/C2-311[»]
2FZGX-ray2.25A/C2-311[»]
2FZKX-ray2.50A/C2-311[»]
2H3EX-ray2.30A/C2-311[»]
2HSEX-ray2.60A/C2-311[»]
2IPOX-ray2.60A/C2-311[»]
2QG9X-ray2.70A/C2-311[»]
2QGFX-ray2.20A/C2-311[»]
3AT1X-ray2.80A/C2-311[»]
3CSUX-ray1.88A/B/C2-311[»]
3D7SX-ray2.80A/C2-311[»]
3MPUX-ray2.86A/C/E2-311[»]
3NPMX-ray2.10A2-311[»]
4AT1X-ray2.60A/C2-311[»]
4E2FX-ray2.80A/C/E/G/I/K2-311[»]
4F04X-ray2.30A/C2-311[»]
4FYVX-ray2.10A/C2-311[»]
4FYWX-ray2.10A/C2-311[»]
4FYXX-ray2.09A/C2-311[»]
4FYYX-ray1.94A/C2-311[»]
4WTOX-ray2.03A/C2-311[»]
5AT1X-ray2.60A/C2-311[»]
5VMQX-ray2.01A/B/C2-311[»]
6AT1X-ray2.60A/C2-311[»]
7AT1X-ray2.80A/C2-311[»]
8AT1X-ray2.80A/C2-311[»]
8ATCX-ray2.50A/C2-311[»]
9ATCX-ray2.40A2-311[»]
ProteinModelPortaliP0A786
SMRiP0A786
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260722, 54 interactors
ComplexPortaliCPX-3091 Aspartate carbamoyltransferase complex
DIPiDIP-35089N
IntActiP0A786, 3 interactors
MINTiP0A786
STRINGi316385.ECDH10B_4440

2D gel databases

SWISS-2DPAGEiP0A786

Proteomic databases

PaxDbiP0A786
PRIDEiP0A786

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC77202; AAC77202; b4245
BAE78244; BAE78244; BAE78244
GeneIDi948767
KEGGiecj:JW4204
eco:b4245
PATRICifig|1411691.4.peg.2456

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB0798
EcoGeneiEG10805 pyrB

Phylogenomic databases

eggNOGiENOG4105CXT Bacteria
COG0540 LUCA
HOGENOMiHOG000022685
InParanoidiP0A786
KOiK00609
PhylomeDBiP0A786

Enzyme and pathway databases

UniPathwayi
UPA00070;UER00116

BioCyciEcoCyc:ASPCARBCAT-MONOMER
MetaCyc:ASPCARBCAT-MONOMER
BRENDAi2.1.3.2 2026
SABIO-RKiP0A786

Miscellaneous databases

EvolutionaryTraceiP0A786

Protein Ontology

More...PROi		PR:P0A786

Family and domain databases

Gene3Di3.40.50.1370, 2 hits
HAMAPiMF_00001 Asp_carb_tr, 1 hit
InterProiView protein in InterPro
IPR006132 Asp/Orn_carbamoyltranf_P-bd
IPR006130 Asp/Orn_carbamoylTrfase
IPR036901 Asp/Orn_carbamoylTrfase_sf
IPR002082 Asp_carbamoyltransf
IPR006131 Asp_carbamoyltransf_Asp/Orn-bd
PANTHERiPTHR11405:SF16 PTHR11405:SF16, 1 hit
PfamiView protein in Pfam
PF00185 OTCace, 1 hit
PF02729 OTCace_N, 1 hit
PRINTSiPR00100 AOTCASE
PR00101 ATCASE
SUPFAMiSSF53671 SSF53671, 1 hit
TIGRFAMsiTIGR00670 asp_carb_tr, 1 hit
PROSITEiView protein in PROSITE
PS00097 CARBAMOYLTRANSFERASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPYRB_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P0A786
Secondary accession number(s): P00479
, Q2M662, Q47555, Q47557
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 21, 1986
Last sequence update: January 23, 2007
Last modified: December 5, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  4. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again