UniProtKB - P0A766 (RSXA_ECOLI)
Protein
Ion-translocating oxidoreductase complex subunit A
Gene
rsxA
Organism
Escherichia coli (strain K12)
Status
Functioni
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity). Required to maintain the reduced state of SoxR. Probably transfers electron from NAD(P)H to SoxR (PubMed:12773378).UniRule annotation1 Publication
GO - Biological processi
- electron transport chain Source: UniProtKB-UniRule
Keywordsi
Molecular function | Translocase |
Biological process | Electron transport, Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:G6871-MONOMER |
Protein family/group databases
TCDBi | 3.D.6.1.4, the ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family |
Names & Taxonomyi
Protein namesi | Recommended name: Ion-translocating oxidoreductase complex subunit AUniRule annotationCurated (EC:7.-.-.-UniRule annotationCurated)Alternative name(s): Rsx electron transport complex subunit AUniRule annotationCurated |
Gene namesi | Name:rsxA1 PublicationUniRule annotation Synonyms:rnfA, ydgL Ordered Locus Names:b1627, JW1619 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane UniRule annotation1 Publication; Multi-pass membrane protein UniRule annotation
Plasma Membrane
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 4 | PeriplasmicCurated | 4 | |
Transmembranei | 5 – 25 | HelicalUniRule annotationAdd BLAST | 21 | |
Topological domaini | 26 – 38 | Cytoplasmic1 PublicationAdd BLAST | 13 | |
Transmembranei | 39 – 59 | HelicalUniRule annotationAdd BLAST | 21 | |
Topological domaini | 60 – 62 | Periplasmic1 Publication | 3 | |
Transmembranei | 63 – 83 | HelicalUniRule annotationAdd BLAST | 21 | |
Topological domaini | 84 – 101 | Cytoplasmic1 PublicationAdd BLAST | 18 | |
Transmembranei | 102 – 122 | HelicalUniRule annotationAdd BLAST | 21 | |
Topological domaini | 123 – 133 | Periplasmic1 PublicationAdd BLAST | 11 | |
Transmembranei | 134 – 154 | HelicalUniRule annotationAdd BLAST | 21 | |
Topological domaini | 155 – 170 | Cytoplasmic1 PublicationAdd BLAST | 16 | |
Transmembranei | 171 – 191 | HelicalUniRule annotationAdd BLAST | 21 | |
Topological domaini | 192 – 193 | Periplasmic2 Publications | 2 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000214289 | 1 – 193 | Ion-translocating oxidoreductase complex subunit AAdd BLAST | 193 |
Proteomic databases
PaxDbi | P0A766 |
PRIDEi | P0A766 |
Interactioni
Subunit structurei
The complex is composed of six subunits: RsxA, RsxB, RsxC, RsxD, RsxE and RsxG.
UniRule annotation1 PublicationProtein-protein interaction databases
BioGRIDi | 4261327, 41 interactors |
STRINGi | 511145.b1627 |
Family & Domainsi
Sequence similaritiesi
Belongs to the NqrDE/RnfAE family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG4657, Bacteria |
HOGENOMi | CLU_095255_1_0_6 |
InParanoidi | P0A766 |
PhylomeDBi | P0A766 |
Family and domain databases
HAMAPi | MF_00459, RsxA_RnfA, 1 hit |
InterProi | View protein in InterPro IPR011293, Ion_transpt_RnfA/RsxA IPR003667, NqrDE/RnfAE |
Pfami | View protein in Pfam PF02508, Rnf-Nqr, 1 hit |
PIRSFi | PIRSF006102, NQR_DE, 1 hit |
TIGRFAMsi | TIGR01943, rnfA, 1 hit |
i Sequence
Sequence statusi: Complete.
P0A766-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDYLLLFVG TVLVNNFVLV KFLGLCPFMG VSKKLETAMG MGLATTFVMT
60 70 80 90 100
LASICAWLID TWILIPLNLI YLRTLAFILV IAVVVQFTEM VVRKTSPVLY
110 120 130 140 150
RLLGIFLPLI TTNCAVLGVA LLNINLGHNF LQSALYGFSA AVGFSLVMVL
160 170 180 190
FAAIRERLAV ADVPAPFRGN AIALITAGLM SLAFMGFSGL VKL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74699.1 AP009048 Genomic DNA Translation: BAE76486.1 |
PIRi | E64919 |
RefSeqi | NP_416144.1, NC_000913.3 WP_000133193.1, NZ_STEB01000003.1 |
Genome annotation databases
EnsemblBacteriai | AAC74699; AAC74699; b1627 BAE76486; BAE76486; BAE76486 |
GeneIDi | 58459765 946148 |
KEGGi | ecj:JW1619 eco:b1627 |
PATRICi | fig|1411691.4.peg.634 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U00096 Genomic DNA Translation: AAC74699.1 AP009048 Genomic DNA Translation: BAE76486.1 |
PIRi | E64919 |
RefSeqi | NP_416144.1, NC_000913.3 WP_000133193.1, NZ_STEB01000003.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261327, 41 interactors |
STRINGi | 511145.b1627 |
Protein family/group databases
TCDBi | 3.D.6.1.4, the ion (h(+) or na(+))-translocating nadh:ferredoxin oxidoreductase (nfo or rnf) family |
Proteomic databases
PaxDbi | P0A766 |
PRIDEi | P0A766 |
Genome annotation databases
EnsemblBacteriai | AAC74699; AAC74699; b1627 BAE76486; BAE76486; BAE76486 |
GeneIDi | 58459765 946148 |
KEGGi | ecj:JW1619 eco:b1627 |
PATRICi | fig|1411691.4.peg.634 |
Organism-specific databases
EchoBASEi | EB3692 |
Phylogenomic databases
eggNOGi | COG4657, Bacteria |
HOGENOMi | CLU_095255_1_0_6 |
InParanoidi | P0A766 |
PhylomeDBi | P0A766 |
Enzyme and pathway databases
BioCyci | EcoCyc:G6871-MONOMER |
Miscellaneous databases
PROi | PR:P0A766 |
Family and domain databases
HAMAPi | MF_00459, RsxA_RnfA, 1 hit |
InterProi | View protein in InterPro IPR011293, Ion_transpt_RnfA/RsxA IPR003667, NqrDE/RnfAE |
Pfami | View protein in Pfam PF02508, Rnf-Nqr, 1 hit |
PIRSFi | PIRSF006102, NQR_DE, 1 hit |
TIGRFAMsi | TIGR01943, rnfA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RSXA_ECOLI | |
Accessioni | P0A766Primary (citable) accession number: P0A766 Secondary accession number(s): P76181, Q2MB70 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 7, 2005 |
Last sequence update: | June 7, 2005 | |
Last modified: | February 10, 2021 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families