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Protein

Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase

Gene

citX

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein.2 Publications

Catalytic activityi

2'-(5-triphosphoribosyl)-3'-dephospho-CoA + citrate lyase apo-[acyl-carrier protein] = citrate lyase holo-[acyl-carrier protein] + diphosphate.2 Publications

GO - Molecular functioni

  • holo-citrate lyase synthase activity Source: EcoCyc

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase

Enzyme and pathway databases

BioCyciEcoCyc:G6340-MONOMER
MetaCyc:G6340-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase (EC:2.7.7.612 Publications)
Alternative name(s):
Apo-ACP nucleodityltransferase
Holo-ACP synthase
Holo-citrate lyase synthase
Gene namesi
Name:citX
Synonyms:ybdU
Ordered Locus Names:b0614, JW0606
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13540 citX

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002146851 – 183Apo-citrate lyase phosphoribosyl-dephospho-CoA transferaseAdd BLAST183

Proteomic databases

PaxDbiP0A6G5
PRIDEiP0A6G5

Expressioni

Inductioni

Repressed by H-NS. Part of the citCDEFXG operon.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4260860, 9 interactors
IntActiP0A6G5, 8 interactors
STRINGi316385.ECDH10B_0682

Structurei

3D structure databases

ProteinModelPortaliP0A6G5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CitX family.Curated

Phylogenomic databases

eggNOGiENOG4105YGP Bacteria
COG3697 LUCA
HOGENOMiHOG000130710
InParanoidiP0A6G5
KOiK05964
PhylomeDBiP0A6G5

Family and domain databases

HAMAPiMF_00398 CitX, 1 hit
InterProiView protein in InterPro
IPR005551 CitX
PfamiView protein in Pfam
PF03802 CitX, 1 hit
TIGRFAMsiTIGR03124 citrate_citX, 1 hit

Sequencei

Sequence statusi: Complete.

P0A6G5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHLLPELASH HAVSIPELLV SRDERQARQH VWLKRHPVPL VSFTVVAPGP
60 70 80 90 100
IKDSEVTRRI FNHGVTALRA LAAKQGWQIQ EQAALVSASG PEGMLSIAAP
110 120 130 140 150
ARDLKLATIE LEHSHPLGRL WDIDVLTPEG EILSRRDYSL PPRRCLLCEQ
160 170 180
SAAVCARGKT HQLTDLLNRM EALLNDVDAC NVN
Length:183
Mass (Da):20,270
Last modified:March 29, 2005 - v1
Checksum:i22BC3420DABE06D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA Translation: AAB40814.1
U00096 Genomic DNA Translation: AAC73715.1
AP009048 Genomic DNA Translation: BAE76354.1
PIRiD64795
RefSeqiNP_415147.1, NC_000913.3
WP_000550422.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73715; AAC73715; b0614
BAE76354; BAE76354; BAE76354
GeneIDi949084
KEGGiecj:JW0606
eco:b0614
PATRICifig|1411691.4.peg.1654

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA Translation: AAB40814.1
U00096 Genomic DNA Translation: AAC73715.1
AP009048 Genomic DNA Translation: BAE76354.1
PIRiD64795
RefSeqiNP_415147.1, NC_000913.3
WP_000550422.1, NZ_LN832404.1

3D structure databases

ProteinModelPortaliP0A6G5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260860, 9 interactors
IntActiP0A6G5, 8 interactors
STRINGi316385.ECDH10B_0682

Proteomic databases

PaxDbiP0A6G5
PRIDEiP0A6G5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73715; AAC73715; b0614
BAE76354; BAE76354; BAE76354
GeneIDi949084
KEGGiecj:JW0606
eco:b0614
PATRICifig|1411691.4.peg.1654

Organism-specific databases

EchoBASEiEB3310
EcoGeneiEG13540 citX

Phylogenomic databases

eggNOGiENOG4105YGP Bacteria
COG3697 LUCA
HOGENOMiHOG000130710
InParanoidiP0A6G5
KOiK05964
PhylomeDBiP0A6G5

Enzyme and pathway databases

BioCyciEcoCyc:G6340-MONOMER
MetaCyc:G6340-MONOMER

Miscellaneous databases

PROiPR:P0A6G5

Family and domain databases

HAMAPiMF_00398 CitX, 1 hit
InterProiView protein in InterPro
IPR005551 CitX
PfamiView protein in Pfam
PF03802 CitX, 1 hit
TIGRFAMsiTIGR03124 citrate_citX, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCITX_ECOLI
AccessioniPrimary (citable) accession number: P0A6G5
Secondary accession number(s): P77563, Q2MBK2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: March 29, 2005
Last modified: November 7, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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Main funding by: National Institutes of Health

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