UniProtKB - P0A4L2 (THIO1_NOSSO)
Protein
Thioredoxin 1
Gene
trxA
Organism
Nostoc sp. (strain ATCC 29151 / PCC 7119) (Anabaena sp.)
Status
Functioni
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
GO - Molecular functioni
- protein disulfide oxidoreductase activity Source: InterPro
GO - Biological processi
- cell redox homeostasis Source: InterPro
- glycerol ether metabolic process Source: InterPro
Keywordsi
Biological process | Electron transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Thioredoxin 1Short name: Trx-1 Alternative name(s): Thioredoxin-M |
Gene namesi | Name:trxA |
Organismi | Nostoc sp. (strain ATCC 29151 / PCC 7119) (Anabaena sp.) |
Taxonomic identifieri | 1168 [NCBI] |
Taxonomic lineagei | Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc › |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed1 Publication | |||
ChainiPRO_0000120073 | 2 – 107 | Thioredoxin 1Add BLAST | 106 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 32 ↔ 35 | Redox-activePROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bondFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 107 | ThioredoxinPROSITE-ProRule annotationAdd BLAST | 106 |
Sequence similaritiesi
Belongs to the thioredoxin family.Curated
Keywords - Domaini
Redox-active centerFamily and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR005746, Thioredoxin IPR036249, Thioredoxin-like_sf IPR017937, Thioredoxin_CS IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF00085, Thioredoxin, 1 hit |
PIRSFi | PIRSF000077, Thioredoxin, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
TIGRFAMsi | TIGR01068, thioredoxin, 1 hit |
PROSITEi | View protein in PROSITE PS00194, THIOREDOXIN_1, 1 hit PS51352, THIOREDOXIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P0A4L2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAAAQVTDS TFKQEVLDSD VPVLVDFWAP WCGPCRMVAP VVDEIAQQYE
60 70 80 90 100
GKIKVVKVNT DENPQVASQY GIRSIPTLMI FKGGQKVDMV VGAVPKTTLS
QTLEKHL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M14736 Genomic DNA Translation: AAA22049.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M14736 Genomic DNA Translation: AAA22049.1 |
3D structure databases
SMRi | P0A4L2 |
ModBasei | Search... |
Family and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR005746, Thioredoxin IPR036249, Thioredoxin-like_sf IPR017937, Thioredoxin_CS IPR013766, Thioredoxin_domain |
Pfami | View protein in Pfam PF00085, Thioredoxin, 1 hit |
PIRSFi | PIRSF000077, Thioredoxin, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
TIGRFAMsi | TIGR01068, thioredoxin, 1 hit |
PROSITEi | View protein in PROSITE PS00194, THIOREDOXIN_1, 1 hit PS51352, THIOREDOXIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | THIO1_NOSSO | |
Accessioni | P0A4L2Primary (citable) accession number: P0A4L2 Secondary accession number(s): P06544 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1988 |
Last sequence update: | January 23, 2007 | |
Last modified: | August 12, 2020 | |
This is version 56 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- SIMILARITY comments
Index of protein domains and families