UniProtKB - P0A1R7 (DBHA_SALTI)
Protein
DNA-binding protein HU-alpha
Gene
hupA
Organism
Salmonella typhi
Status
Functioni
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.By similarity
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- chromosome condensation Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding |
Biological process | DNA condensation |
Names & Taxonomyi
Protein namesi | Recommended name: DNA-binding protein HU-alphaAlternative name(s): HU-2 NS2 |
Gene namesi | Name:hupA Ordered Locus Names:STY3715, t3461 |
Organismi | Salmonella typhi |
Taxonomic identifieri | 90370 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Salmonella › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000104968 | 1 – 90 | DNA-binding protein HU-alphaAdd BLAST | 90 |
Interactioni
Subunit structurei
Heterodimer of an alpha and a beta chain.
By similarityProtein-protein interaction databases
STRINGi | 220341.16504591 |
Family & Domainsi
Sequence similaritiesi
Belongs to the bacterial histone-like protein family.Curated
Phylogenomic databases
eggNOGi | COG0776, Bacteria |
HOGENOMi | CLU_105066_3_1_6 |
Family and domain databases
Gene3Di | 4.10.520.10, 1 hit |
InterProi | View protein in InterPro IPR000119, Hist_DNA-bd IPR020816, Histone-like_DNA-bd_CS IPR010992, IHF-like_DNA-bd_dom_sf |
PANTHERi | PTHR33175, PTHR33175, 1 hit |
Pfami | View protein in Pfam PF00216, Bac_DNA_binding, 1 hit |
PRINTSi | PR01727, DNABINDINGHU |
SMARTi | View protein in SMART SM00411, BHL, 1 hit |
SUPFAMi | SSF47729, SSF47729, 1 hit |
PROSITEi | View protein in PROSITE PS00045, HISTONE_LIKE, 1 hit |
i Sequence
Sequence statusi: Complete.
P0A1R7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNKTQLIDVI ADKAELSKTQ AKAALESTLA AITESLKEGD AVQLVGFGTF
60 70 80 90
KVNHRAERTG RNPQTGKEIK IAAANVPAFV SGKALKDAVK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL513382 Genomic DNA Translation: CAD09474.1 AE014613 Genomic DNA Translation: AAO70977.1 |
RefSeqi | NP_457904.1, NC_003198.1 WP_001044509.1, NZ_WSUR01000043.1 |
Genome annotation databases
EnsemblBacteriai | AAO70977; AAO70977; t3461 CAD09474; CAD09474; CAD09474 |
GeneIDi | 50276954 |
KEGGi | stt:t3461 sty:STY3715 |
PATRICi | fig|220341.7.peg.3787 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL513382 Genomic DNA Translation: CAD09474.1 AE014613 Genomic DNA Translation: AAO70977.1 |
RefSeqi | NP_457904.1, NC_003198.1 WP_001044509.1, NZ_WSUR01000043.1 |
3D structure databases
SMRi | P0A1R7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 220341.16504591 |
Genome annotation databases
EnsemblBacteriai | AAO70977; AAO70977; t3461 CAD09474; CAD09474; CAD09474 |
GeneIDi | 50276954 |
KEGGi | stt:t3461 sty:STY3715 |
PATRICi | fig|220341.7.peg.3787 |
Phylogenomic databases
eggNOGi | COG0776, Bacteria |
HOGENOMi | CLU_105066_3_1_6 |
Family and domain databases
Gene3Di | 4.10.520.10, 1 hit |
InterProi | View protein in InterPro IPR000119, Hist_DNA-bd IPR020816, Histone-like_DNA-bd_CS IPR010992, IHF-like_DNA-bd_dom_sf |
PANTHERi | PTHR33175, PTHR33175, 1 hit |
Pfami | View protein in Pfam PF00216, Bac_DNA_binding, 1 hit |
PRINTSi | PR01727, DNABINDINGHU |
SMARTi | View protein in SMART SM00411, BHL, 1 hit |
SUPFAMi | SSF47729, SSF47729, 1 hit |
PROSITEi | View protein in PROSITE PS00045, HISTONE_LIKE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DBHA_SALTI | |
Accessioni | P0A1R7Primary (citable) accession number: P0A1R7 Secondary accession number(s): P15148 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 1, 2005 |
Last sequence update: | March 1, 2005 | |
Last modified: | December 2, 2020 | |
This is version 89 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |