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Protein

Enterotoxin type C-3

Gene

entC3

Organism
Staphylococcus aureus
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.

GO - Molecular functioni

Keywordsi

Molecular functionEnterotoxin, Superantigen, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Enterotoxin type C-3
Alternative name(s):
SEC3
Gene namesi
Name:entC3
OrganismiStaphylococcus aureus
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Protein family/group databases

Allergomei2141 Sta a SEC

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Add BLAST27
ChainiPRO_000003561128 – 266Enterotoxin type C-3Add BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi120 ↔ 137

Keywords - PTMi

Disulfide bond

Structurei

Secondary structure

1266
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP0A0L5
SMRiP0A0L5
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP0A0L5

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR008992 Enterotoxin
IPR006126 Staph/Strept_toxin_CS
IPR006173 Staph_tox_OB
IPR016091 SuperAg_toxin_C
IPR013307 Superantigen_bac
IPR006123 Toxin_b-grasp_Staph/Strep
IPR006177 Toxin_bac
PfamiView protein in Pfam
PF02876 Stap_Strp_tox_C, 1 hit
PF01123 Stap_Strp_toxin, 1 hit
PRINTSiPR00279 BACTRLTOXIN
PR01898 SAGSUPRFAMLY
SUPFAMiSSF50203 SSF50203, 1 hit
SSF54334 SSF54334, 1 hit
PROSITEiView protein in PROSITE
PS00277 STAPH_STREP_TOXIN_1, 1 hit
PS00278 STAPH_STREP_TOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P0A0L5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYKRLFISRV ILIFALILVI STPNVLAESQ PDPMPDDLHK SSEFTGTMGN
60 70 80 90 100
MKYLYDDHYV SATKVKSVDK FLAHDLIYNI SDKKLKNYDK VKTELLNEDL
110 120 130 140 150
AKKYKDEVVD VYGSNYYVNC YFSSKDNVGK VTGGKTCMYG GITKHEGNHF
160 170 180 190 200
DNGNLQNVLV RVYENKRNTI SFEVQTDKKS VTAQELDIKA RNFLINKKNL
210 220 230 240 250
YEFNSSPYET GYIKFIENNG NTFWYDMMPA PGDKFDQSKY LMMYNDNKTV
260
DSKSVKIEVH LTTKNG
Length:266
Mass (Da):30,671
Last modified:March 1, 2005 - v1
Checksum:i5ED8A32D11FFCA59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X51661 Genomic DNA Translation: CAA35972.1
PIRiS11885
RefSeqiWP_000278088.1, NZ_UHCA01000001.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X51661 Genomic DNA Translation: CAA35972.1
PIRiS11885
RefSeqiWP_000278088.1, NZ_UHCA01000001.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JCKX-ray3.50B/D28-266[»]
1JWMX-ray2.70D28-266[»]
1JWSX-ray2.60D28-266[»]
1JWUX-ray2.30D28-266[»]
1KLGX-ray2.40D28-266[»]
1KLUX-ray1.93D28-266[»]
1SJEX-ray2.45D28-266[»]
1SJHX-ray2.25D28-266[»]
1T5XX-ray2.50D28-266[»]
2AQ1X-ray2.10B/D/F/H28-266[»]
2AQ2X-ray1.80B28-266[»]
2AQ3X-ray2.30B/D/F/H28-266[»]
2IPKX-ray2.30D28-266[»]
3BVGX-ray2.00A28-266[»]
3BVMX-ray2.00A28-266[»]
3BVZX-ray2.30A28-266[»]
3BYTX-ray2.30B/D/F/H28-266[»]
3BYYX-ray2.20B28-266[»]
3BZDX-ray2.30B28-266[»]
ProteinModelPortaliP0A0L5
SMRiP0A0L5
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei2141 Sta a SEC

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP0A0L5
PROiPR:P0A0L5

Family and domain databases

InterProiView protein in InterPro
IPR008992 Enterotoxin
IPR006126 Staph/Strept_toxin_CS
IPR006173 Staph_tox_OB
IPR016091 SuperAg_toxin_C
IPR013307 Superantigen_bac
IPR006123 Toxin_b-grasp_Staph/Strep
IPR006177 Toxin_bac
PfamiView protein in Pfam
PF02876 Stap_Strp_tox_C, 1 hit
PF01123 Stap_Strp_toxin, 1 hit
PRINTSiPR00279 BACTRLTOXIN
PR01898 SAGSUPRFAMLY
SUPFAMiSSF50203 SSF50203, 1 hit
SSF54334 SSF54334, 1 hit
PROSITEiView protein in PROSITE
PS00277 STAPH_STREP_TOXIN_1, 1 hit
PS00278 STAPH_STREP_TOXIN_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiENTC3_STAAU
AccessioniPrimary (citable) accession number: P0A0L5
Secondary accession number(s): P23313
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2005
Last modified: November 7, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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