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Protein

Potassium-transporting ATPase KdpC subunit 2

Gene

kdpC2

Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.UniRule annotation

GO - Molecular functioni

Keywordsi

Biological processIon transport, Potassium transport, Transport
LigandATP-binding, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium-transporting ATPase KdpC subunit 2UniRule annotation
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] C chain 2UniRule annotation
Potassium-binding and translocating subunit C 2UniRule annotation
Potassium-translocating ATPase C chain 2UniRule annotation
Gene namesi
Name:kdpC2UniRule annotation
Ordered Locus Names:SAV0074
OrganismiStaphylococcus aureus (strain Mu50 / ATCC 700699)
Taxonomic identifieri158878 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000002481 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001970141 – 185Potassium-transporting ATPase KdpC subunit 2Add BLAST185

Proteomic databases

PaxDbiP0A059

Interactioni

Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC.UniRule annotation

Protein-protein interaction databases

STRINGi158878.SAV0074

Structurei

3D structure databases

SMRiP0A059
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KdpC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108R80 Bacteria
COG2156 LUCA
HOGENOMiHOG000244124
KOiK01548
OMAiQANGSIM

Family and domain databases

HAMAPiMF_00276 KdpC, 1 hit
InterProiView protein in InterPro
IPR003820 KdpC
PANTHERiPTHR30042 PTHR30042, 1 hit
PfamiView protein in Pfam
PF02669 KdpC, 1 hit
PIRSFiPIRSF001296 K_ATPase_KdpC, 1 hit
TIGRFAMsiTIGR00681 kdpC, 1 hit

Sequencei

Sequence statusi: Complete.

P0A059-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQTIRKSLGL VLIMFVLCGF IFPLTVTALG QVLFPEQANG SLVKQDGKVI
60 70 80 90 100
GSKLIGQQWT EPKYFHGRIS AVNYNMNANE VKESGGPASG GSNYGNSNPE
110 120 130 140 150
LKKRVQETIK QEGKKISSDA VTASGSGLDP DITVDNAKQQ VKRIAKERNI
160 170 180
DASKINHLID ENKQASPMAD DYVNVLKLNI TLDKL
Length:185
Mass (Da):20,159
Last modified:March 1, 2005 - v1
Checksum:i5F8B45FB1812E180
GO

Sequence cautioni

The sequence BAB56236 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB56236.1 Different initiation.
RefSeqiWP_001193482.1, NC_002758.2

Genome annotation databases

EnsemblBacteriaiBAB56236; BAB56236; SAV0074
KEGGisav:SAV0074

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000017 Genomic DNA Translation: BAB56236.1 Different initiation.
RefSeqiWP_001193482.1, NC_002758.2

3D structure databases

SMRiP0A059
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi158878.SAV0074

Proteomic databases

PaxDbiP0A059

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB56236; BAB56236; SAV0074
KEGGisav:SAV0074

Phylogenomic databases

eggNOGiENOG4108R80 Bacteria
COG2156 LUCA
HOGENOMiHOG000244124
KOiK01548
OMAiQANGSIM

Family and domain databases

HAMAPiMF_00276 KdpC, 1 hit
InterProiView protein in InterPro
IPR003820 KdpC
PANTHERiPTHR30042 PTHR30042, 1 hit
PfamiView protein in Pfam
PF02669 KdpC, 1 hit
PIRSFiPIRSF001296 K_ATPase_KdpC, 1 hit
TIGRFAMsiTIGR00681 kdpC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiKDPC2_STAAM
AccessioniPrimary (citable) accession number: P0A059
Secondary accession number(s): Q932L1, Q9LC48
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2005
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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