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Protein

Regulatory protein cro

Gene

cro

Organism
Salmonella phage P22 (Bacteriophage P22)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi13 – 32H-T-H motifSequence analysisAdd BLAST20

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Regulatory protein cro
Alternative name(s):
Antirepressor
Gene namesi
Name:cro
OrganismiSalmonella phage P22 (Bacteriophage P22)
Taxonomic identifieri10754 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaeP22virus
Virus hostiSalmonella typhimurium [TaxID: 90371]
Proteomesi
  • UP000001795 Componenti: Genome
  • UP000007960 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000775781 – 61Regulatory protein croAdd BLAST61

Proteomic databases

PRIDEiP09964

Expressioni

Keywords - Developmental stagei

Early protein

Structurei

Secondary structure

161
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP09964
SMRiP09964
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP09964

Family & Domainsi

Phylogenomic databases

KOiK22302
OrthoDBiVOG090001XN

Family and domain databases

InterProiView protein in InterPro
IPR010982 Lambda_DNA-bd_dom_sf
SUPFAMiSSF47413 SSF47413, 1 hit

Sequencei

Sequence statusi: Complete.

P09964-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYKKDVIDHF GTQRAVAKAL GISDAAVSQW KEVIPEKDAY RLEIVTAGAL
60
KYQENAYRQA A
Length:61
Mass (Da):6,828
Last modified:July 1, 1989 - v1
Checksum:iCD37A130D8CF14AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M12584 Genomic DNA Translation: AAA32268.1
AF217253 Genomic DNA Translation: AAF75025.1
BK000583 Genomic DNA Translation: DAA01022.1
M10074 Genomic DNA Translation: AAA32273.1
PIRiA25867 RGBP22
RefSeqiNP_059607.1, NC_002371.2

Genome annotation databases

GeneIDi1262827
KEGGivg:1262827

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M12584 Genomic DNA Translation: AAA32268.1
AF217253 Genomic DNA Translation: AAF75025.1
BK000583 Genomic DNA Translation: DAA01022.1
M10074 Genomic DNA Translation: AAA32273.1
PIRiA25867 RGBP22
RefSeqiNP_059607.1, NC_002371.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1RZSNMR-A1-61[»]
ProteinModelPortaliP09964
SMRiP09964
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP09964

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1262827
KEGGivg:1262827

Phylogenomic databases

KOiK22302
OrthoDBiVOG090001XN

Miscellaneous databases

EvolutionaryTraceiP09964

Family and domain databases

InterProiView protein in InterPro
IPR010982 Lambda_DNA-bd_dom_sf
SUPFAMiSSF47413 SSF47413, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRCRO_BPP22
AccessioniPrimary (citable) accession number: P09964
Secondary accession number(s): Q38659, Q7PCF1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: November 7, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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