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Protein

Interferon alpha-inducible protein 6

Gene

IFI6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis (PubMed:15685448, PubMed:17823654, PubMed:26244642). However, it has also been shown to have a pro-apoptotic activity (PubMed:27673746). Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells (PubMed:25757571).5 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiviral defense, Apoptosis, Immunity, Innate immunity

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-909733 Interferon alpha/beta signaling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Interferon alpha-inducible protein 6Curated
Alternative name(s):
Interferon-induced protein 6-161 Publication
Short name:
Ifi-6-161 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IFI6Imported
Synonyms:G1P31 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000126709.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4054 IFI6

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
147572 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P09912

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei4 – 24HelicalSequence analysisAdd BLAST21
Transmembranei41 – 61HelicalSequence analysisAdd BLAST21
Transmembranei75 – 95HelicalSequence analysisAdd BLAST21
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
2537

Open Targets

More...
OpenTargetsi
ENSG00000126709

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA28466

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IFI6

Domain mapping of disease mutations (DMDM)

More...
DMDMi
20178294

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000087411 – 130Interferon alpha-inducible protein 6Add BLAST130

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Glycosylated.1 Publication

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
P09912

PRoteomics IDEntifications database

More...
PRIDEi
P09912

ProteomicsDB human proteome resource

More...
ProteomicsDBi
52273
52274 [P09912-2]
52275 [P09912-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P09912

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P09912

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by type-I interferon (PubMed:14728724, PubMed:17823654). Up-regulated upon Dengue virus type 2/DENV2 infection (at protein level) (PubMed:26244642).3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000126709 Expressed in 196 organ(s), highest expression level in placenta

CleanEx database of gene expression profiles

More...
CleanExi
HS_IFI6

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P09912 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA005543

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CIB1; the interaction is direct.1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
108812, 2 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P09912

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P09912

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the IFI6/IFI27 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163178

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112988

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG006160

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P09912

Identification of Orthologs from Complete Genome Data

More...
OMAi
MSWSAIM

Database of Orthologous Groups

More...
OrthoDBi
1593440at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P09912

TreeFam database of animal gene trees

More...
TreeFami
TF340510

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.246.160, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009311 IFI6/IFI27-like
IPR038213 IFI6/IFI27-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR16932 PTHR16932, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06140 Ifi-6-16, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform A (identifier: P09912-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRQKAVSLFL CYLLLFTCSG VEAGKKKCSE SSDSGSGFWK ALTFMAVGGG
60 70 80 90 100
LAVAGLPALG FTGAGIAANS VAASLMSWSA ILNGGGVPAG GLVATLQSLG
110 120 130
AGGSSVVIGN IGALMGYATH KYLDSEEDEE
Length:130
Mass (Da):12,927
Last modified:April 16, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1C2992A59203B38
GO
Isoform B (identifier: P09912-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     24-24: G → GENAG

Show »
Length:134
Mass (Da):13,298
Checksum:iAEEE9641CDAF5CA1
GO
Isoform C (identifier: P09912-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     24-24: G → GENAGKDAG

Show »
Length:138
Mass (Da):13,670
Checksum:iD6498E4F200EB939
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti8L → V (PubMed:3017706).Curated1
Sequence conflicti8L → V (PubMed:7596809).Curated1
Sequence conflicti116G → R (PubMed:3017706).Curated1
Sequence conflicti116G → R (PubMed:7596809).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_00150224G → GENAG in isoform B. 1 Publication1
Alternative sequenceiVSP_00150324G → GENAGKDAG in isoform C. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X02492 mRNA Translation: CAA26322.1
U22970 Genomic DNA Translation: AAC50159.1
U22970 Genomic DNA Translation: AAC50160.1
U22970 Genomic DNA Translation: AAC50161.1
BT006850 mRNA Translation: AAP35496.1
AK314488 mRNA Translation: BAG37089.1
AL445490 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07744.1
CH471059 Genomic DNA Translation: EAX07745.1
CH471059 Genomic DNA Translation: EAX07746.1
BC011601 mRNA Translation: AAH11601.1
BC015603 mRNA Translation: AAH15603.1
BN000257 mRNA Translation: CAE12275.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS306.1 [P09912-1]
CCDS307.1 [P09912-2]
CCDS308.1 [P09912-3]

Protein sequence database of the Protein Information Resource

More...
PIRi
A26316

NCBI Reference Sequences

More...
RefSeqi
NP_002029.3, NM_002038.3 [P09912-1]
NP_075010.1, NM_022872.2 [P09912-2]
NP_075011.1, NM_022873.2 [P09912-3]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.523847
Hs.730125

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000339145; ENSP00000342513; ENSG00000126709 [P09912-3]
ENST00000361157; ENSP00000354736; ENSG00000126709 [P09912-1]
ENST00000362020; ENSP00000355152; ENSG00000126709 [P09912-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2537

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:2537

UCSC genome browser

More...
UCSCi
uc001bon.2 human [P09912-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02492 mRNA Translation: CAA26322.1
U22970 Genomic DNA Translation: AAC50159.1
U22970 Genomic DNA Translation: AAC50160.1
U22970 Genomic DNA Translation: AAC50161.1
BT006850 mRNA Translation: AAP35496.1
AK314488 mRNA Translation: BAG37089.1
AL445490 Genomic DNA No translation available.
CH471059 Genomic DNA Translation: EAX07744.1
CH471059 Genomic DNA Translation: EAX07745.1
CH471059 Genomic DNA Translation: EAX07746.1
BC011601 mRNA Translation: AAH11601.1
BC015603 mRNA Translation: AAH15603.1
BN000257 mRNA Translation: CAE12275.1
CCDSiCCDS306.1 [P09912-1]
CCDS307.1 [P09912-2]
CCDS308.1 [P09912-3]
PIRiA26316
RefSeqiNP_002029.3, NM_002038.3 [P09912-1]
NP_075010.1, NM_022872.2 [P09912-2]
NP_075011.1, NM_022873.2 [P09912-3]
UniGeneiHs.523847
Hs.730125

3D structure databases

ProteinModelPortaliP09912
SMRiP09912
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi108812, 2 interactors

PTM databases

iPTMnetiP09912
PhosphoSitePlusiP09912

Polymorphism and mutation databases

BioMutaiIFI6
DMDMi20178294

Proteomic databases

PeptideAtlasiP09912
PRIDEiP09912
ProteomicsDBi52273
52274 [P09912-2]
52275 [P09912-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
2537
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000339145; ENSP00000342513; ENSG00000126709 [P09912-3]
ENST00000361157; ENSP00000354736; ENSG00000126709 [P09912-1]
ENST00000362020; ENSP00000355152; ENSG00000126709 [P09912-2]
GeneIDi2537
KEGGihsa:2537
UCSCiuc001bon.2 human [P09912-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
2537
DisGeNETi2537
EuPathDBiHostDB:ENSG00000126709.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
IFI6
HGNCiHGNC:4054 IFI6
HPAiHPA005543
MIMi147572 gene
neXtProtiNX_P09912
OpenTargetsiENSG00000126709
PharmGKBiPA28466

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000163178
HOGENOMiHOG000112988
HOVERGENiHBG006160
InParanoidiP09912
OMAiMSWSAIM
OrthoDBi1593440at2759
PhylomeDBiP09912
TreeFamiTF340510

Enzyme and pathway databases

ReactomeiR-HSA-909733 Interferon alpha/beta signaling

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
IFI6 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
IFI6

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
2537

Protein Ontology

More...
PROi
PR:P09912

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000126709 Expressed in 196 organ(s), highest expression level in placenta
CleanExiHS_IFI6
GenevisibleiP09912 HS

Family and domain databases

Gene3Di1.10.246.160, 1 hit
InterProiView protein in InterPro
IPR009311 IFI6/IFI27-like
IPR038213 IFI6/IFI27-like_sf
PANTHERiPTHR16932 PTHR16932, 1 hit
PfamiView protein in Pfam
PF06140 Ifi-6-16, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIFI6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P09912
Secondary accession number(s): Q13141
, Q13142, Q5VVR2, Q5VVR3, Q6IE95, Q969M8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: April 16, 2002
Last modified: January 16, 2019
This is version 153 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
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