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1 to 25 of 92  Show
  1. 1
    "Sequence of an intestinal cDNA encoding human gastric inhibitory polypeptide precursor."
    Takeda J., Seino Y., Tanaka K., Fukumoto H., Kayano T., Takahashi H., Mitani T., Kurono M., Suzuki T., Tobe T., Imura H.
    Proc. Natl. Acad. Sci. U.S.A. 84:7005-7008(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is mapped to 4 other entries.

  2. 2
    "Gastric inhibitory polypeptide: structure and chromosomal localization of the human gene."
    Inagaki N., Seino Y., Takeda J., Yano H., Yamada Y., Bell G.I., Eddy R.L. Jr., Fukushima Y., Byers M.G., Shows T.B., Imura H.
    Mol. Endocrinol. 3:1014-1021(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  3. 3
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT GLY-103.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50448 other entries.

  4. 4
    "The isolation and sequencing of human gastric inhibitory peptide (GIP)."
    Moody A.J., Thim L., Valverde I.
    FEBS Lett. 172:142-148(1984) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 52-93.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  5. 5
    "NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide."
    Alana I., Hewage C.M., Malthouse J.P., Parker J.C., Gault V.A., O'Harte F.P.
    Biochem. Biophys. Res. Commun. 325:281-286(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR OF 52-81.
    Category: Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "Ageing and endocrine cells of human duodenum."
    Sandstrom O., El-Salhy M.
    Mech. Ageing Dev. 108:39-48(1999) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400526, Reactome:R-HSA-400512.
  7. 7
    "Osteoblast-derived cells express functional glucose-dependent insulinotropic peptide receptors."
    Bollag R.J., Zhong Q., Phillips P., Min L., Zhong L., Cameron R., Mulloy A.L., Rasmussen H., Qin F., Ding K.H., Isales C.M.
    Endocrinology 141:1228-1235(2000) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400540.

    This publication is mapped to 1 other entry.

  8. 8
    "Characterization of the cellular and metabolic effects of a novel enzyme-resistant antagonist of glucose-dependent insulinotropic polypeptide."
    Gault V.A., O'Harte F.P., Harriott P., Flatt P.R.
    Biochem. Biophys. Res. Commun. 290:1420-1426(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Substitution of Glu(3) in GIP with proline produces a novel dipeptidylpeptidase IV-resistant GIP antagonist which inhibits GIP-induced cAMP generation and insulin secretion with high sensitivity and specificity in vitro.
    Source: GeneRIF:2695.
  9. 9
    "Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus."
    Feldman D.S., Zamah A.M., Pierce K.L., Miller W.E., Kelly F., Rapacciuolo A., Rockman H.A., Koch W.J., Luttrell L.M.
    J. Biol. Chem. 277:28631-28640(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400540.

    This publication is mapped to 111 other entries.

  10. 10
    "Similarities and differences in the coupling of human beta1- and beta2-adrenoceptors to Gs(alpha) splice variants."
    Wenzel-Seifert K., Liu H.Y., Seifert R.
    Biochem. Pharmacol. 64:9-20(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400540.

    This publication is mapped to 126 other entries.

  11. 11
    "Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway."
    Ehses J.A., Pelech S.L., Pederson R.A., McIntosh C.H.
    J. Biol. Chem. 277:37088-37097(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing.
    Annotation: activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.
    Source: GeneRIF:2695.

    This publication is mapped to 3 other entries.

  12. 12
    "Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects."
    Zhu X., Zhou A., Dey A., Norrbom C., Carroll R., Zhang C., Laurent V., Lindberg I., Ugleholdt R., Holst J.J., Steiner D.F.
    Proc. Natl. Acad. Sci. U.S.A. 99:10293-10298(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400483, Reactome:R-HSA-400526.

    This publication is mapped to 8 other entries.

  13. 13
    "Analysis of the putative promoter region of the GIP receptor gene (GIPR) in GIP-dependent Cushing's syndrome (CS)."
    Antonini S.R., N'Diaye N., Hamet P., Tremblay J., Lacroix A.
    Endocr. Res. 28:755-756(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Mutation in promoter region of gip receptor gene are unlikely to underlie GIP-dependent Cushing syndrome.
    Source: GeneRIF:2695.

    This publication is mapped to 2 other entries.

  14. 14
    "Characterization of the 5-HT6 receptor coupled to Ca2+ signaling using an enabling chimeric G-protein."
    Zhang J.Y., Nawoschik S., Kowal D., Smith D., Spangler T., Ochalski R., Schechter L., Dunlop J.
    Eur. J. Pharmacol. 472:33-38(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400540.

    This publication is mapped to 111 other entries.

  15. 15
    "Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects."
    Meier J.J., Nauck M.A., Kranz D., Holst J.J., Deacon C.F., Gaeckler D., Schmidt W.E., Gallwitz B.
    Diabetes 53:654-662(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: delayed elimination in renal insufficiency.
    Source: GeneRIF:2695.

    This publication is mapped to 1 other entry.

  16. 16
    "Elevated plasma glucose-dependent insulinotropic polypeptide associates with hyperinsulinemia in impaired glucose tolerance."
    Theodorakis M.J., Carlson O., Muller D.C., Egan J.M.
    Diabetes Care 27:1692-1698(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Elevated plasma GIP levels are correlated with hyperinsulinemia in the impaired glucose-tolerant state whereas type 2 diabetes is associated with a failure to secrete adequate amounts of GIP.
    Source: GeneRIF:2695.
  17. 17
    "Bombesin and nutrients independently and additively regulate hormone release from GIP/Ins cells."
    Li L., Wice B.M.
    Am. J. Physiol. Endocrinol. Metab. 288:E208-15(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function, PTM / Processing.
    Annotation: bombesin and nutrients additively stimulate GIP release from GIP/Ins cells.
    Source: GeneRIF:2695.
  18. 18
    "Clinical endocrinology and metabolism. Glucose-dependent insulinotropic polypeptide/gastric inhibitory polypeptide."
    Meier J.J., Nauck M.A.
    Best Pract. Res. Clin. Endocrinol. Metab. 18:587-606(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: GIP augments glucose-stimulated insulin secretion and acts as an endogenous inhibitor of gastric acid secretion--REVIEW.
    Source: GeneRIF:2695.
  19. 19
    "Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders."
    Gorrell M.D.
    Clin. Sci. 108:277-292(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400540, Reactome:R-HSA-400542.

    This publication is mapped to 2 other entries.

  20. 20
    "Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight."
    Schou J.H., Pilgaard K., Vilsboll T., Jensen C.B., Deacon C.F., Holst J.J., Volund A., Madsbad S., Vaag A.A.
    J. Clin. Endocrinol. Metab. 90:4912-4919(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Reduced secretion or action of GLP-1 or GIP does not explain a relative reduced beta-cell responsiveness to glucose or the slightly elevated plasma glucose concentrations observed in young low birth weight men.
    Source: GeneRIF:2695.
  21. 21
    "A novel mechanism for the suppression of a voltage-gated potassium channel by glucose-dependent insulinotropic polypeptide: protein kinase A-dependent endocytosis."
    Kim S.J., Choi W.S., Han J.S., Warnock G., Fedida D., McIntosh C.H.
    J. Biol. Chem. 280:28692-28700(2005) [PubMed] [Europe PMC] [Abstract]
    Category: PTM / Processing.
    Annotation: GIP stimulates insulin secretion by potentiating events underlying membrane depolarization and exerting direct effects on exocytosis.
    Source: GeneRIF:2695.

    This publication is mapped to 8 other entries.

  22. 22
    "Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes."
    Meier J.J., Gallwitz B., Askenas M., Vollmer K., Deacon C.F., Holst J.J., Schmidt W.E., Nauck M.A.
    Diabetologia 48:1872-1881(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: The relationship between insulin resistance and the insulin secretion to GIP suggests that beta cell secretory function in response to different stimuli increases adaptively when insulin sensitivity is diminished as in gestational diabetes.
    Source: GeneRIF:2695.
  23. 23
    "Biological actions of the incretins GIP and GLP-1 and therapeutic perspectives in patients with type 2 diabetes."
    Gautier J.F., Fetita S., Sobngwi E., Salaun-Martin C.
    Diabetes Metab. 31:233-242(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: GIP is rapidly degraded into inactive metabolites by the enzyme dipeptidyl-peptidase-IV. (review).
    Source: GeneRIF:2695.

    This publication is mapped to 1 other entry.

  24. 24
    "Human duodenal enteroendocrine cells: source of both incretin peptides, GLP-1 and GIP."
    Theodorakis M.J., Carlson O., Michopoulos S., Doyle M.E., Juhaszova M., Petraki K., Egan J.M.
    Am. J. Physiol. Endocrinol. Metab. 290:E550-9(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400540, Reactome:R-HSA-400483, Reactome:R-HSA-400470.

    This publication is mapped to 15 other entries.

  25. 25
    "Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor."
    Ugleholdt R., Poulsen M.L., Holst P.J., Irminger J.C., Orskov C., Pedersen J., Rosenkilde M.M., Zhu X., Steiner D.F., Holst J.J.
    J. Biol. Chem. 281:11050-11057(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Pathway.
    Source: Reactome:R-HSA-400483, Reactome:R-HSA-400526.

    This publication is mapped to 15 other entries.

1 to 25 of 92  Show
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