Sod2

Functionⁱ

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityⁱ

2 superoxide + 2 H⁺ = O₂ + H₂O₂.

Cofactorⁱ

Mn²⁺By similarityNote: Binds 1 Mn²⁺ ion per subunit.By similarity

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	50	ManganeseBy similarity	1
Metal bindingⁱ	98	ManganeseBy similarity	1
Metal bindingⁱ	183	ManganeseBy similarity	1
Metal bindingⁱ	187	ManganeseBy similarity	1

GO - Molecular functionⁱ

DNA binding Source: MGI
enzyme binding Source: MGI
identical protein binding Source: MGI
manganese ion binding Source: UniProtKB
metal ion binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
oxidoreductase activity
Source: CACAO
Inferred from mutant phenotypeⁱ
- 15205258
oxygen binding Source: MGI
superoxide dismutase activity
Source: MGI
Inferred from direct assayⁱ

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Source: MGI
Inferred from mutant phenotypeⁱ
- 16873728
age-dependent response to oxidative stress
Source: MGI
Inferred from mutant phenotypeⁱ
- 11226230
age-dependent response to reactive oxygen species Source: UniProtKB
aging
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
apoptotic mitochondrial changes
Source: MGI
Inferred from mutant phenotypeⁱ
- 11226230
cellular response to ethanol Source: Ensembl
detection of oxygen
Source: MGI
Inferred from mutant phenotypeⁱ
- 11156968
erythrophore differentiation
Source: MGI
Inferred from mutant phenotypeⁱ
- 15205258
glutathione metabolic process
Source: MGI
Inferred from mutant phenotypeⁱ
- 10049502
heart development
Source: MGI
Inferred from mutant phenotypeⁱ
- 7493016
hemopoiesis
Source: MGI
Inferred from mutant phenotypeⁱ
- 16219542
- 8790408
hydrogen peroxide biosynthetic process Source: MGI
hydrogen peroxide metabolic process Source: MGI
intrinsic apoptotic signaling pathway in response to DNA damage
Source: MGI
Inferred from mutant phenotypeⁱ
- 15642323
intrinsic apoptotic signaling pathway in response to oxidative stress
Source: MGI
Inferred from mutant phenotypeⁱ
- 15642323
iron ion homeostasis
Source: MGI
Inferred from mutant phenotypeⁱ
- 15205258
liver development
Source: MGI
Inferred from mutant phenotypeⁱ
- 17367743
locomotory behavior
Source: MGI
Inferred from mutant phenotypeⁱ
- 8790408
mitochondrion organization
Source: MGI
Inferred from mutant phenotypeⁱ
negative regulation of apoptotic process Source: MGI
negative regulation of cell proliferation Source: MGI
negative regulation of fat cell differentiation
Source: MGI
Inferred from mutant phenotypeⁱ
- 16219542
negative regulation of fibroblast proliferation
Source: MGI
Inferred from direct assayⁱ
- 18218638
negative regulation of neuron apoptotic process Source: MGI
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Source: MGI
negative regulation of vascular smooth muscle cell proliferation Source: MGI
neuron development
Source: MGI
Inferred from mutant phenotypeⁱ
- 8790408
oxygen homeostasis Source: MGI
positive regulation of cell migration Source: MGI
positive regulation of nitric oxide biosynthetic process
Source: MGI
Inferred from mutant phenotypeⁱ
- 15637112
positive regulation of vascular associated smooth muscle cell apoptotic process Source: MGI
positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching Source: MGI
post-embryonic development
Source: MGI
Inferred from mutant phenotypeⁱ
- 7493016
- 8790408
protein homooligomerization Source: MGI
protein homotetramerization Source: MGI
regulation of blood pressure
Source: MGI
Inferred from mutant phenotypeⁱ
- 17023572
regulation of catalytic activity
Source: MGI
Inferred from mutant phenotypeⁱ
- 9927656
regulation of mitochondrial membrane potential
Source: MGI
Inferred from mutant phenotypeⁱ
- 17367743
regulation of transcription by RNA polymerase II
Source: MGI
Inferred from direct assayⁱ
- 17670746
release of cytochrome c from mitochondria
Source: MGI
Inferred from mutant phenotypeⁱ
- 10212301
- 15642323
removal of superoxide radicals
Source: MGI
Inferred from mutant phenotypeⁱ
- 16873728
respiratory electron transport chain
Source: MGI
Inferred from mutant phenotypeⁱ
- 11226230
- 19478076
response to activity
Source: MGI
Inferred from mutant phenotypeⁱ
- 15781740
response to axon injury
Source: MGI
Inferred from mutant phenotypeⁱ
- 16677818
response to cadmium ion Source: Ensembl
response to cold Source: Ensembl
response to drug Source: MGI
response to electrical stimulus Source: Ensembl
response to gamma radiation
Source: MGI
Inferred from genetic interactionⁱ
- 15182862
response to hydrogen peroxide
Source: MGI
Inferred from mutant phenotypeⁱ
- 15642323
response to hyperoxia
Source: MGI
Inferred from mutant phenotypeⁱ
- 11796207
response to hypoxia Source: Ensembl
response to immobilization stress Source: Ensembl
response to isolation stress Source: Ensembl
response to L-ascorbic acid Source: Ensembl
response to lipopolysaccharide Source: Ensembl
response to magnetism Source: Ensembl
response to manganese ion Source: Ensembl
response to nutrient levels Source: MGI
response to oxidative stress
Source: MGI
Inferred from mutant phenotypeⁱ
- 15182862
- 19478076
response to reactive oxygen species
Source: MGI
Inferred from mutant phenotypeⁱ
response to selenium ion Source: Ensembl
response to silicon dioxide Source: Ensembl
response to superoxide
Source: MGI
Inferred from mutant phenotypeⁱ
- 11156968
- 15642323
response to zinc ion Source: Ensembl
superoxide anion generation
Source: MGI
Inferred from mutant phenotypeⁱ
superoxide metabolic process
Source: MGI
Inferred from mutant phenotypeⁱ
vasodilation
Source: MGI
Inferred from mutant phenotypeⁱ
- 15637112

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Oxidoreductase
Ligand	Manganese, Metal-binding

Enzyme and pathway databases

Reactomeⁱ	R-MMU-2151201 Transcriptional activation of mitochondrial biogenesis R-MMU-3299685 Detoxification of Reactive Oxygen Species

Reactomeⁱ

R-MMU-2151201 Transcriptional activation of mitochondrial biogenesis
R-MMU-3299685 Detoxification of Reactive Oxygen Species

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Superoxide dismutase [Mn], mitochondrial (EC:1.15.1.1)
Gene namesⁱ	Name:Sod2 Synonyms:Sod-2
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 17

Organism-specific databases

MGIⁱ	MGI:98352 Sod2

Keywords - Cellular componentⁱ

Mitochondrion

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	122	K → R: Reverses IR-Induced increases in superoxide and genomic Instability in SIRT3-deficient mice. 1 Publication		1

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transit peptideⁱ	1 – 24	MitochondrionAdd BLAST		24
ChainⁱPRO_0000032871	25 – 222	Superoxide dismutase [Mn], mitochondrialAdd BLAST		198

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	58	Nitrated tyrosineBy similarity	1
Modified residueⁱ	68	N6-acetyllysine; alternateCombined sources	1
Modified residueⁱ	68	N6-succinyllysine; alternateCombined sources	1
Modified residueⁱ	75	N6-acetyllysine; alternateCombined sources	1
Modified residueⁱ	75	N6-succinyllysine; alternateCombined sources	1
Modified residueⁱ	114	N6-acetyllysineCombined sources	1
Modified residueⁱ	122	N6-acetyllysine; alternateCombined sources1 Publication	1
Modified residueⁱ	122	N6-succinyllysine; alternateCombined sources	1
Modified residueⁱ	130	N6-acetyllysine; alternateCombined sources	1
Modified residueⁱ	130	N6-succinyllysine; alternateCombined sources	1
Modified residueⁱ	202	N6-acetyllysineCombined sources	1

Post-translational modificationⁱ

Nitrated under oxidative stress. Nitration coupled with oxidation inhibits the catalytic activity (By similarity).By similarity

Acetylation at Lys-122 decreases enzymatic activity. Deacetylated by SIRT3 upon exposure to ionizing radiations or after long fasting.1 Publication

Polyubiquitinated; leading to proteasomal degradation. Deubiquitinated by USP36 which increases protein stability.By similarity

Keywords - PTMⁱ

Acetylation, Nitration, Ubl conjugation

Proteomic databases

EPDⁱ	P09671
PaxDbⁱ	P09671
PeptideAtlas More...PeptideAtlasⁱ	P09671
PRIDEⁱ	P09671
TopDownProteomicsⁱ	P09671

2D gel databases

REPRODUCTION-2DPAGE More...REPRODUCTION-2DPAGEⁱ	IPI00109109 P09671
SWISS-2DPAGEⁱ	P09671

PTM databases

iPTMnetⁱ	P09671
PhosphoSitePlusⁱ	P09671
SwissPalmⁱ	P09671

Expressionⁱ

Inductionⁱ

Expression is regulated by KRIT1.1 Publication

Gene expression databases

Bgeeⁱ	ENSMUSG00000006818 Expressed in 339 organ(s), highest expression level in cardiac ventricle
CleanExⁱ	MM_SOD2
ExpressionAtlasⁱ	P09671 baseline and differential
Genevisibleⁱ	P09671 MM

Interactionⁱ

Subunit structureⁱ

Homotetramer.

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
Polg	P54099	2	EBI-1635071,EBI-863636
Tp53	P02340	2	EBI-1635071,EBI-474016

GO - Molecular functionⁱ

enzyme binding Source: MGI
identical protein binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	203388, 2 interactors
IntActⁱ	P09671, 7 interactors
Molecular INTeraction database More...MINTⁱ	P09671
STRINGⁱ	10090.ENSMUSP00000007012

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P09671
SMRⁱ	P09671
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the iron/manganese superoxide dismutase family.Curated

Keywords - Domainⁱ

Transit peptide

Phylogenomic databases

eggNOGⁱ	KOG0876 Eukaryota COG0605 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000011877
HOGENOMⁱ	HOG000013583
HOVERGENⁱ	HBG004451
InParanoidⁱ	P09671
KEGG Orthology (KO) More...KOⁱ	K04564
OMAⁱ	KWGSFDK
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0MVL
PhylomeDBⁱ	P09671
TreeFamⁱ	TF105132

Family and domain databases

Gene3Dⁱ	1.10.287.990, 1 hit 2.40.500.20, 1 hit
InterProⁱ	View protein in InterPro IPR001189 Mn/Fe_SOD IPR019833 Mn/Fe_SOD_BS IPR019832 Mn/Fe_SOD_C IPR019831 Mn/Fe_SOD_N IPR036324 Mn/Fe_SOD_N_sf IPR036314 SOD_C_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02777 Sod_Fe_C, 1 hit PF00081 Sod_Fe_N, 1 hit
PIRSFⁱ	PIRSF000349 SODismutase, 1 hit
PRINTSⁱ	PR01703 MNSODISMTASE
SUPFAMⁱ	SSF46609 SSF46609, 1 hit SSF54719 SSF54719, 1 hit
PROSITEⁱ	View protein in PROSITE PS00088 SOD_MN, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P09671-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLCRAACSTG RRLGPVAGAA GSRHKHSLPD LPYDYGALEP HINAQIMQLH 
        60         70         80         90        100
HSKHHAAYVN NLNATEEKYH EALAKGDVTT QVALQPALKF NGGGHINHTI 
       110        120        130        140        150
FWTNLSPKGG GEPKGELLEA IKRDFGSFEK FKEKLTAVSV GVQGSGWGWL 
       160        170        180        190        200
GFNKEQGRLQ IAACSNQDPL QGTTGLIPLL GIDVWEHAYY LQYKNVRPDY 
       210        220 
LKAIWNVINW ENVTERYTAC KK

Length:222

Mass (Da):24,603

Last modified:July 15, 1998 - v3

Checksum:ⁱ9AE804C55A8357D9

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	5	A → G in AAH18173 (PubMed:16141072).Curated	1
Sequence conflictⁱ	18	G → V in CAA28645 (PubMed:3797253).Curated	1
Sequence conflictⁱ	138	V → M (PubMed:3797253).Curated	1
Sequence conflictⁱ	138	V → M (PubMed:7875582).Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X04972 mRNA Translation: CAA28645.1 Z18857 mRNA Translation: CAA79308.1 L35528 , L35525, L35526, L35527 Genomic DNA Translation: AAB60902.1 S78846 , S78832, S78842, S78844 Genomic DNA Translation: AAB34899.1 AK002428 mRNA Translation: BAB22095.1 AK002534 mRNA Translation: BAB22170.1 AK012354 mRNA Translation: BAB28183.1 BC010548 mRNA Translation: AAH10548.1 BC018173 mRNA Translation: AAH18173.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS28399.1
PIRⁱ	I57023
NCBI Reference Sequences More...RefSeqⁱ	NP_038699.2, NM_013671.3
UniGeneⁱ	Mm.290876

Genome annotation databases

Ensemblⁱ	ENSMUST00000007012; ENSMUSP00000007012; ENSMUSG00000006818
GeneIDⁱ	20656
KEGGⁱ	mmu:20656
UCSC genome browser More...UCSCⁱ	uc008alv.1 mouse

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P09671	Superoxide dismutase		MOUSE		222	UniRef100_P09671

Protein	Similar proteins		Species	Score	Length	Source
P09671	Superoxide dismutase [Mn], mitochondrial		RAT		222	UniRef90_P09671
Superoxide dismutase		MOUSE		222
Superoxide dismutase		NEOLE		232
Superoxide dismutase		MESAU		222
Superoxide dismutase		ICTTR		222
+15

Protein	Similar proteins		Species	Score	Length	Source
P09671	Superoxide dismutase [Mn], mitochondrial		RAT		222	UniRef50_P09671
Superoxide dismutase [Mn], mitochondrial (Fragment)		PETMA		144
Superoxide dismutase		MOUSE		222
Superoxide dismutase		NEOLE		232
Superoxide dismutase		ICTTR		222
+92

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X04972 mRNA Translation: CAA28645.1 Z18857 mRNA Translation: CAA79308.1 L35528 , L35525, L35526, L35527 Genomic DNA Translation: AAB60902.1 S78846 , S78832, S78842, S78844 Genomic DNA Translation: AAB34899.1 AK002428 mRNA Translation: BAB22095.1 AK002534 mRNA Translation: BAB22170.1 AK012354 mRNA Translation: BAB28183.1 BC010548 mRNA Translation: AAH10548.1 BC018173 mRNA Translation: AAH18173.1
CCDSⁱ	CCDS28399.1
PIRⁱ	I57023
RefSeqⁱ	NP_038699.2, NM_013671.3
UniGeneⁱ	Mm.290876

3D structure databases

ProteinModelPortalⁱ	P09671
SMRⁱ	P09671
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	203388, 2 interactors
IntActⁱ	P09671, 7 interactors
MINTⁱ	P09671
STRINGⁱ	10090.ENSMUSP00000007012

PTM databases

iPTMnetⁱ	P09671
PhosphoSitePlusⁱ	P09671
SwissPalmⁱ	P09671

2D gel databases

REPRODUCTION-2DPAGEⁱ	IPI00109109 P09671
SWISS-2DPAGEⁱ	P09671

Proteomic databases

EPDⁱ	P09671
PaxDbⁱ	P09671
PeptideAtlasⁱ	P09671
PRIDEⁱ	P09671
TopDownProteomicsⁱ	P09671

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000007012; ENSMUSP00000007012; ENSMUSG00000006818
GeneIDⁱ	20656
KEGGⁱ	mmu:20656
UCSCⁱ	uc008alv.1 mouse

Organism-specific databases

CTDⁱ	6648
MGIⁱ	MGI:98352 Sod2

Phylogenomic databases

eggNOGⁱ	KOG0876 Eukaryota COG0605 LUCA
GeneTreeⁱ	ENSGT00390000011877
HOGENOMⁱ	HOG000013583
HOVERGENⁱ	HBG004451
InParanoidⁱ	P09671
KOⁱ	K04564
OMAⁱ	KWGSFDK
OrthoDBⁱ	EOG091G0MVL
PhylomeDBⁱ	P09671
TreeFamⁱ	TF105132

Enzyme and pathway databases

Reactomeⁱ	R-MMU-2151201 Transcriptional activation of mitochondrial biogenesis R-MMU-3299685 Detoxification of Reactive Oxygen Species

Reactomeⁱ

R-MMU-2151201 Transcriptional activation of mitochondrial biogenesis
R-MMU-3299685 Detoxification of Reactive Oxygen Species

Miscellaneous databases

ChiTaRSⁱ	Sod2 mouse
Protein Ontology More...PROⁱ	PR:P09671
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000006818 Expressed in 339 organ(s), highest expression level in cardiac ventricle
CleanExⁱ	MM_SOD2
ExpressionAtlasⁱ	P09671 baseline and differential
Genevisibleⁱ	P09671 MM

Family and domain databases

Gene3Dⁱ	1.10.287.990, 1 hit 2.40.500.20, 1 hit
InterProⁱ	View protein in InterPro IPR001189 Mn/Fe_SOD IPR019833 Mn/Fe_SOD_BS IPR019832 Mn/Fe_SOD_C IPR019831 Mn/Fe_SOD_N IPR036324 Mn/Fe_SOD_N_sf IPR036314 SOD_C_sf
Pfamⁱ	View protein in Pfam PF02777 Sod_Fe_C, 1 hit PF00081 Sod_Fe_N, 1 hit
PIRSFⁱ	PIRSF000349 SODismutase, 1 hit
PRINTSⁱ	PR01703 MNSODISMTASE
SUPFAMⁱ	SSF46609 SSF46609, 1 hit SSF54719 SSF54719, 1 hit
PROSITEⁱ	View protein in PROSITE PS00088 SOD_MN, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SODM_MOUSE
Accessionⁱ	P09671Primary (citable) accession number: P09671 Secondary accession number(s): Q64670, Q8VEM5
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
	Last sequence update:	July 15, 1998
	Last modified:	November 7, 2018
	This is version 189 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P09671 (SODM_MOUSE)

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Superoxide dismutase [Mn], mitochondrial

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Mitochondrion

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

2D gel databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ