UniProtKB - P09549 (DEDD_ECOLI)
Protein
Cell division protein DedD
Gene
dedD
Organism
Escherichia coli (strain K12)
Status
Functioni
Non-essential cell division protein that could be required for efficient cell constriction.UniRule annotation1 Publication
GO - Molecular functioni
- peptidoglycan binding Source: EcoCyc
GO - Biological processi
- cytokinetic process Source: EcoCyc
Keywordsi
Biological process | Cell cycle, Cell division |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10218-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Cell division protein DedDUniRule annotationCurated |
Gene namesi | Name:dedD1 PublicationUniRule annotation Ordered Locus Names:b2314, JW5378 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell inner membrane UniRule annotationCurated; Single-pass membrane protein UniRule annotation
Note: Localizes at the septal ring.UniRule annotation2 Publications
Plasma Membrane
- integral component of plasma membrane Source: UniProtKB-UniRule
Other locations
- cell division site Source: EcoCyc
- cell septum Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 9 – 29 | HelicalUniRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePathology & Biotechi
Disruption phenotypei
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000079851 | 1 – 220 | Cell division protein DedDAdd BLAST | 220 |
Proteomic databases
jPOSTi | P09549 |
PaxDbi | P09549 |
PRIDEi | P09549 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4260528, 50 interactors |
STRINGi | 511145.b2314 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 138 – 217 | SPORUniRule annotationAdd BLAST | 80 |
Domaini
The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.UniRule annotation1 Publication
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG3147, Bacteria |
HOGENOMi | CLU_068683_1_1_6 |
Family and domain databases
HAMAPi | MF_02022, DedD, 1 hit |
InterProi | View protein in InterPro IPR032898, DedD IPR007730, SPOR-like_dom IPR036680, SPOR-like_sf |
Pfami | View protein in Pfam PF05036, SPOR, 1 hit |
SUPFAMi | SSF110997, SSF110997, 1 hit |
PROSITEi | View protein in PROSITE PS51724, SPOR, 1 hit |
i Sequence
Sequence statusi: Complete.
P09549-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASKFQNRLV GTIVLVALGV IVLPGLLDGQ KKHYQDEFAA IPLVPKAGDR
60 70 80 90 100
DEPDMMPAAT QALPTQPPEG AAEEVRAGDA AAPSLDPATI AANNTEFEPE
110 120 130 140 150
PAPVAPPKPK PVEPPKPKVE APPAPKPEPK PVVEEKAAPT GKAYVVQLGA
160 170 180 190 200
LKNADKVNEI VGKLRGAGYR VYTSPSTPVQ GKITRILVGP DASKDKLKGS
210 220
LGELKQLSGL SGVVMGYTPN
Sequence cautioni
The sequence AAA23967 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M68934 Genomic DNA Translation: AAA23967.1 Different initiation. U00096 Genomic DNA Translation: AAC75374.2 AP009048 Genomic DNA Translation: BAA16162.2 |
PIRi | H65003, XMECDD |
RefSeqi | NP_416817.2, NC_000913.3 WP_000146992.1, NZ_STEB01000008.1 |
Genome annotation databases
EnsemblBacteriai | AAC75374; AAC75374; b2314 BAA16162; BAA16162; BAA16162 |
GeneIDi | 58388066 944971 |
KEGGi | ecj:JW5378 eco:b2314 |
PATRICi | fig|511145.12.peg.2409 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M68934 Genomic DNA Translation: AAA23967.1 Different initiation. U00096 Genomic DNA Translation: AAC75374.2 AP009048 Genomic DNA Translation: BAA16162.2 |
PIRi | H65003, XMECDD |
RefSeqi | NP_416817.2, NC_000913.3 WP_000146992.1, NZ_STEB01000008.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4260528, 50 interactors |
STRINGi | 511145.b2314 |
Proteomic databases
jPOSTi | P09549 |
PaxDbi | P09549 |
PRIDEi | P09549 |
Genome annotation databases
EnsemblBacteriai | AAC75374; AAC75374; b2314 BAA16162; BAA16162; BAA16162 |
GeneIDi | 58388066 944971 |
KEGGi | ecj:JW5378 eco:b2314 |
PATRICi | fig|511145.12.peg.2409 |
Organism-specific databases
EchoBASEi | EB0214 |
Phylogenomic databases
eggNOGi | COG3147, Bacteria |
HOGENOMi | CLU_068683_1_1_6 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10218-MONOMER |
Miscellaneous databases
PROi | PR:P09549 |
Family and domain databases
HAMAPi | MF_02022, DedD, 1 hit |
InterProi | View protein in InterPro IPR032898, DedD IPR007730, SPOR-like_dom IPR036680, SPOR-like_sf |
Pfami | View protein in Pfam PF05036, SPOR, 1 hit |
SUPFAMi | SSF110997, SSF110997, 1 hit |
PROSITEi | View protein in PROSITE PS51724, SPOR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DEDD_ECOLI | |
Accessioni | P09549Primary (citable) accession number: P09549 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1989 |
Last sequence update: | April 27, 2001 | |
Last modified: | February 10, 2021 | |
This is version 135 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families