UniProtKB - P09549 (DEDD_ECOLI)
Protein
Cell division protein DedD
Gene
dedD
Organism
Escherichia coli (strain K12)
Status
Functioni
Non-essential cell division protein that could be required for efficient cell constriction.UniRule annotation1 Publication
GO - Molecular functioni
- peptidoglycan binding Source: EcoCyc
GO - Biological processi
- cytokinetic process Source: EcoCyc
Keywordsi
Biological process | Cell cycle, Cell division |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10218-MONOMER ECOL316407:JW5378-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Cell division protein DedDUniRule annotationCurated |
Gene namesi | Name:dedD1 PublicationUniRule annotation Ordered Locus Names:b2314, JW5378 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotationCurated; Single-pass membrane protein UniRule annotation Note: Localizes at the septal ring.UniRule annotation2 Publications
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 9 – 29 | HelicalUniRule annotationAdd BLAST | 21 |
GO - Cellular componenti
- cell division site Source: EcoCyc
- cell septum Source: EcoCyc
- integral component of plasma membrane Source: UniProtKB-UniRule
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePathology & Biotechi
Disruption phenotypei
Deletion causes a mild cell chaining phenotype.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000079851 | 1 – 220 | Cell division protein DedDAdd BLAST | 220 |
Proteomic databases
jPOSTi | P09549 |
PaxDbi | P09549 |
PRIDEi | P09549 |
Interactioni
Protein-protein interaction databases
BioGridi | 4260528, 50 interactors |
STRINGi | 511145.b2314 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 138 – 217 | SPORUniRule annotationAdd BLAST | 80 |
Domaini
The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.UniRule annotation1 Publication
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG4108S3P Bacteria COG3147 LUCA |
HOGENOMi | HOG000279501 |
KOi | K03749 |
Family and domain databases
HAMAPi | MF_02022 DedD, 1 hit |
InterProi | View protein in InterPro IPR032898 DedD IPR007730 SPOR-like_dom IPR036680 SPOR-like_sf |
Pfami | View protein in Pfam PF05036 SPOR, 1 hit |
SUPFAMi | SSF110997 SSF110997, 1 hit |
PROSITEi | View protein in PROSITE PS51724 SPOR, 1 hit |
i Sequence
Sequence statusi: Complete.
P09549-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASKFQNRLV GTIVLVALGV IVLPGLLDGQ KKHYQDEFAA IPLVPKAGDR
60 70 80 90 100
DEPDMMPAAT QALPTQPPEG AAEEVRAGDA AAPSLDPATI AANNTEFEPE
110 120 130 140 150
PAPVAPPKPK PVEPPKPKVE APPAPKPEPK PVVEEKAAPT GKAYVVQLGA
160 170 180 190 200
LKNADKVNEI VGKLRGAGYR VYTSPSTPVQ GKITRILVGP DASKDKLKGS
210 220
LGELKQLSGL SGVVMGYTPN
Sequence cautioni
The sequence AAA23967 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M68934 Genomic DNA Translation: AAA23967.1 Different initiation. U00096 Genomic DNA Translation: AAC75374.2 AP009048 Genomic DNA Translation: BAA16162.2 |
PIRi | H65003 XMECDD |
RefSeqi | NP_416817.2, NC_000913.3 WP_000146992.1, NZ_STEB01000008.1 |
Genome annotation databases
EnsemblBacteriai | AAC75374; AAC75374; b2314 BAA16162; BAA16162; BAA16162 |
GeneIDi | 944971 |
KEGGi | ecj:JW5378 eco:b2314 |
PATRICi | fig|511145.12.peg.2409 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M68934 Genomic DNA Translation: AAA23967.1 Different initiation. U00096 Genomic DNA Translation: AAC75374.2 AP009048 Genomic DNA Translation: BAA16162.2 |
PIRi | H65003 XMECDD |
RefSeqi | NP_416817.2, NC_000913.3 WP_000146992.1, NZ_STEB01000008.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGridi | 4260528, 50 interactors |
STRINGi | 511145.b2314 |
Proteomic databases
jPOSTi | P09549 |
PaxDbi | P09549 |
PRIDEi | P09549 |
Genome annotation databases
EnsemblBacteriai | AAC75374; AAC75374; b2314 BAA16162; BAA16162; BAA16162 |
GeneIDi | 944971 |
KEGGi | ecj:JW5378 eco:b2314 |
PATRICi | fig|511145.12.peg.2409 |
Organism-specific databases
EchoBASEi | EB0214 |
Phylogenomic databases
eggNOGi | ENOG4108S3P Bacteria COG3147 LUCA |
HOGENOMi | HOG000279501 |
KOi | K03749 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG10218-MONOMER ECOL316407:JW5378-MONOMER |
Miscellaneous databases
PROi | PR:P09549 |
Family and domain databases
HAMAPi | MF_02022 DedD, 1 hit |
InterProi | View protein in InterPro IPR032898 DedD IPR007730 SPOR-like_dom IPR036680 SPOR-like_sf |
Pfami | View protein in Pfam PF05036 SPOR, 1 hit |
SUPFAMi | SSF110997 SSF110997, 1 hit |
PROSITEi | View protein in PROSITE PS51724 SPOR, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DEDD_ECOLI | |
Accessioni | P09549Primary (citable) accession number: P09549 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1989 |
Last sequence update: | April 27, 2001 | |
Last modified: | November 13, 2019 | |
This is version 128 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene