Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 162 (03 Jul 2019)
Sequence version 1 (01 Jul 1989)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Tropomyosin-2

Gene

Tm2

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction. May also regulate motor systems required to maintain nuclear integrity and apico-basal polarity during embryogenesis.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin binding Source: FlyBase
  • actin filament binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMuscle protein

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tropomyosin-2
Alternative name(s):
Tropomyosin I
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tm2
Synonyms:TmI
ORF Names:CG4843
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0004117 Tm2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Pre-cellular embryos exhibit abnormal nuclear divisions with frequent loss of chromosome fragments. During cellularization, apico-basal polarity is also disrupted.1 Publication

Protein family/group databases

Allergome; a platform for allergen knowledge

More...
Allergomei
1517 Dro m 7
4080 Dro m 7.0102
4174 Dro m 7.0104
4175 Dro m 7.0105

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002056861 – 284Tropomyosin-2Add BLAST284

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P09491

PRoteomics IDEntifications database

More...
PRIDEi
P09491

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0004117 Expressed in 34 organ(s), highest expression level in crop (Drosophila)

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P09491 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P09491 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
66917, 75 interactors

Database of interacting proteins

More...
DIPi
DIP-21556N

Protein interaction database and analysis system

More...
IntActi
P09491, 3 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0082535

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P09491

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1 – 284By similarityAdd BLAST284

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tropomyosin family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1003 Eukaryota
ENOG410XR5K LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182712

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P09491

KEGG Orthology (KO)

More...
KOi
K10374

Identification of Orthologs from Complete Genome Data

More...
OMAi
QDKADTC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P09491

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000533 Tropomyosin

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00261 Tropomyosin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00194 TROPOMYOSIN

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00326 TROPOMYOSIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform Thoracic (identifier: P09491-1) [UniParc]FASTAAdd to basket
Also known as: 127, C, t

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDAIKKKMQA MKLEKDNAID KADTCENQAK DANSRADKLN EEVRDLEKKF
60 70 80 90 100
VQVEIDLVTA KEQLEKANTE LEEKEKLLTA TESEVATQNR KVQQIEEDLE
110 120 130 140 150
KSEERSTTAQ QKLLEATQSA DENNRMCKVL ENRSQQDEER MDQLTNQLKE
160 170 180 190 200
ARMLAEDADT KSDEVSRKLA FVEDELEVAE DRVRSGESKI MELEEELKVV
210 220 230 240 250
GNSLKSLEVS EEKANQRVEE FKREMKTLSI KLKEAEQRAE HAEKQVKRLQ
260 270 280
KEVDRLEDRL FNEKEKYKAI CDDLDQTFAE LTGY
Length:284
Mass (Da):32,981
Last modified:July 1, 1989 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i07AD03FDD304EA5F
GO
Isoform Embryonic (identifier: P09491-2) [UniParc]FASTAAdd to basket
Also known as: 129, A, B, e

The sequence of this isoform differs from the canonical sequence as follows:
     259-284: RLFNEKEKYKAICDDLDQTFAELTGY → ELGINKDRYKSLADEMDSTFAELAGY

Show »
Length:284
Mass (Da):32,807
Checksum:i73C07D18BD7AD709
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4KHJ9A0A0B4KHJ9_DROME
Tropomyosin 2, isoform E
Tm2 Dmel\CG4843, dro Tm, DROTROPI1, Ifm(3)3, Ifm(3)5
284Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence ABK30920 differs from that shown. Reason: Frameshift at position 274.Curated
The sequence CAA26142 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti11M → V in AAA28970 (PubMed:6202423).Curated1
Sequence conflicti11M → V in AAA28971 (PubMed:6202423).Curated1
Sequence conflicti88Q → L in AAA28970 (PubMed:6202423).Curated1
Sequence conflicti88Q → L in AAA28971 (PubMed:6202423).Curated1
Sequence conflicti95I → T in AAA28970 (PubMed:6202423).Curated1
Sequence conflicti95I → T in AAA28971 (PubMed:6202423).Curated1
Sequence conflicti255R → D in AAA28970 (PubMed:6202423).Curated1
Sequence conflicti255R → D in AAA28971 (PubMed:6202423).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_006616259 – 284RLFNE…ELTGY → ELGINKDRYKSLADEMDSTF AELAGY in isoform Embryonic. 2 PublicationsAdd BLAST26

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
K02622 Genomic DNA Translation: AAA28970.1
K02623, K02622 Genomic DNA Translation: AAA28971.1
K03277 Genomic DNA Translation: AAA28973.1
K03277 Genomic DNA Translation: AAA28974.1
AE014297 Genomic DNA Translation: AAN13652.1
AE014297 Genomic DNA Translation: AAN13653.1
AE014297 Genomic DNA Translation: AAN13654.2
AY071087 mRNA Translation: AAL48709.1
BT029283 mRNA Translation: ABK30920.1 Frameshift.
BT044580 mRNA Translation: ACI16542.1
X02220 Genomic DNA Translation: CAA26142.1 Sequence problems.

Protein sequence database of the Protein Information Resource

More...
PIRi
A25624
B25624

NCBI Reference Sequences

More...
RefSeqi
NP_001262592.1, NM_001275663.1 [P09491-2]
NP_001262593.1, NM_001275664.1 [P09491-2]
NP_001287337.1, NM_001300408.1 [P09491-2]
NP_524361.4, NM_079637.5 [P09491-2]
NP_732012.1, NM_169644.2 [P09491-2]
NP_732013.2, NM_169645.4 [P09491-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0083078; FBpp0082535; FBgn0004117 [P09491-2]
FBtr0083079; FBpp0082536; FBgn0004117 [P09491-2]
FBtr0083080; FBpp0089270; FBgn0004117 [P09491-1]
FBtr0333920; FBpp0306048; FBgn0004117 [P09491-2]
FBtr0339530; FBpp0308613; FBgn0004117 [P09491-2]
FBtr0345212; FBpp0311407; FBgn0004117 [P09491-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
41853

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG4843

UCSC genome browser

More...
UCSCi
CG4843-RB d. melanogaster

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
K02622 Genomic DNA Translation: AAA28970.1
K02623, K02622 Genomic DNA Translation: AAA28971.1
K03277 Genomic DNA Translation: AAA28973.1
K03277 Genomic DNA Translation: AAA28974.1
AE014297 Genomic DNA Translation: AAN13652.1
AE014297 Genomic DNA Translation: AAN13653.1
AE014297 Genomic DNA Translation: AAN13654.2
AY071087 mRNA Translation: AAL48709.1
BT029283 mRNA Translation: ABK30920.1 Frameshift.
BT044580 mRNA Translation: ACI16542.1
X02220 Genomic DNA Translation: CAA26142.1 Sequence problems.
PIRiA25624
B25624
RefSeqiNP_001262592.1, NM_001275663.1 [P09491-2]
NP_001262593.1, NM_001275664.1 [P09491-2]
NP_001287337.1, NM_001300408.1 [P09491-2]
NP_524361.4, NM_079637.5 [P09491-2]
NP_732012.1, NM_169644.2 [P09491-2]
NP_732013.2, NM_169645.4 [P09491-1]

3D structure databases

SMRiP09491
ModBaseiSearch...

Protein-protein interaction databases

BioGridi66917, 75 interactors
DIPiDIP-21556N
IntActiP09491, 3 interactors
STRINGi7227.FBpp0082535

Protein family/group databases

Allergomei1517 Dro m 7
4080 Dro m 7.0102
4174 Dro m 7.0104
4175 Dro m 7.0105

Proteomic databases

PaxDbiP09491
PRIDEiP09491

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0083078; FBpp0082535; FBgn0004117 [P09491-2]
FBtr0083079; FBpp0082536; FBgn0004117 [P09491-2]
FBtr0083080; FBpp0089270; FBgn0004117 [P09491-1]
FBtr0333920; FBpp0306048; FBgn0004117 [P09491-2]
FBtr0339530; FBpp0308613; FBgn0004117 [P09491-2]
FBtr0345212; FBpp0311407; FBgn0004117 [P09491-2]
GeneIDi41853
KEGGidme:Dmel_CG4843
UCSCiCG4843-RB d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
41853
FlyBaseiFBgn0004117 Tm2

Phylogenomic databases

eggNOGiKOG1003 Eukaryota
ENOG410XR5K LUCA
GeneTreeiENSGT00950000182712
InParanoidiP09491
KOiK10374
OMAiQDKADTC
PhylomeDBiP09491

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
41853

Protein Ontology

More...
PROi
PR:P09491

Gene expression databases

BgeeiFBgn0004117 Expressed in 34 organ(s), highest expression level in crop (Drosophila)
ExpressionAtlasiP09491 baseline and differential
GenevisibleiP09491 DM

Family and domain databases

InterProiView protein in InterPro
IPR000533 Tropomyosin
PfamiView protein in Pfam
PF00261 Tropomyosin, 1 hit
PRINTSiPR00194 TROPOMYOSIN
PROSITEiView protein in PROSITE
PS00326 TROPOMYOSIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTPM2_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P09491
Secondary accession number(s): A0AVW5
, A4V2Y6, P09490, Q24408, Q24427, Q24428, Q8SZ65, Q9VF95
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: July 3, 2019
This is version 162 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again