SSA3

Functionⁱ

Miscellaneous

Present with 6440 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functionⁱ

ATPase activity
Source: SGD
Inferred from genetic interactionⁱ
- 3302682
ATP binding Source: UniProtKB-KW
unfolded protein binding
Source: SGD
Inferred from genetic interactionⁱ
- 9789005

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

protein folding
Source: SGD
Inferred from genetic interactionⁱ
- 9789005
protein quality control for misfolded or incompletely synthesized proteins
Source: SGD
Inferred from mutant phenotypeⁱ
- 24855027
SRP-dependent cotranslational protein targeting to membrane, translocation
Source: SGD
Inferred from mutant phenotypeⁱ
- 8754838

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Stress response
Ligand	ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-28967-MONOMER

BioCycⁱ

YEAST:G3O-28967-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Heat shock protein SSA3
Gene namesⁱ	Name:SSA3 Ordered Locus Names:YBL075C ORF Names:YBL06.07, YBL0610
Organismⁱ	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifierⁱ	559292 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae
Proteomesⁱ	UP000002311 Componentⁱ: Chromosome II

Organism-specific databases

EuPathDBⁱ	FungiDB:YBL075C
Saccharomyces Genome Database More...SGDⁱ	S000000171 SSA3

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000078387	1 – 649	Heat shock protein SSA3Add BLAST		649

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P09435
PaxDbⁱ	P09435
PRIDEⁱ	P09435

2D gel databases

UCD-2DPAGEⁱ	P09435

UCD-2DPAGEⁱ

P09435

Interactionⁱ

GO - Molecular functionⁱ

unfolded protein binding
Source: SGD
Inferred from genetic interactionⁱ
- 9789005

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	32627, 138 interactors
Database of interacting proteins More...DIPⁱ	DIP-2266N
IntActⁱ	P09435, 60 interactors
Molecular INTeraction database More...MINTⁱ	P09435
STRINGⁱ	4932.YBL075C

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P09435
SMRⁱ	P09435
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149300
HOGENOMⁱ	HOG000228135
InParanoidⁱ	P09435
KEGG Orthology (KO) More...KOⁱ	K03283
OMAⁱ	IANPIMT
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C1VPN

Family and domain databases

Gene3Dⁱ	1.20.1270.10, 1 hit 2.60.34.10, 1 hit
InterProⁱ	View protein in InterPro IPR018181 Heat_shock_70_CS IPR029048 HSP70_C_sf IPR029047 HSP70_peptide-bd_sf IPR013126 Hsp_70_fam
PANTHERⁱ	PTHR19375 PTHR19375, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00012 HSP70, 1 hit
PRINTSⁱ	PR00301 HEATSHOCK70
SUPFAMⁱ	SSF100920 SSF100920, 1 hit SSF100934 SSF100934, 1 hit
PROSITEⁱ	View protein in PROSITE PS00297 HSP70_1, 1 hit PS00329 HSP70_2, 1 hit PS01036 HSP70_3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P09435-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSRAVGIDLG TTYSCVAHFS NDRVEIIAND QGNRTTPSYV AFTDTERLIG 
        60         70         80         90        100
DAAKNQAAIN PHNTVFDAKR LIGRKFDDPE VTTDAKHFPF KVISRDGKPV 
       110        120        130        140        150
VQVEYKGETK TFTPEEISSM VLSKMKETAE NYLGTTVNDA VVTVPAYFND 
       160        170        180        190        200
SQRQATKDAG TIAGMNVLRI INEPTAAAIA YGLDKKGRAE HNVLIFDLGG 
       210        220        230        240        250
GTFDVSLLSI DEGVFEVKAT AGDTHLGGED FDNRLVNHLA TEFKRKTKKD 
       260        270        280        290        300
ISNNQRSLRR LRTAAERAKR ALSSSSQTSI EIDSLFEGMD FYTSLTRARF 
       310        320        330        340        350
EELCADLFRS TLEPVEKVLK DSKLDKSQID EIVLVGGSTR IPKIQKLVSD 
       360        370        380        390        400
FFNGKEPNRS INPDEAVAYG AAVQAAILTG DQSTKTQDLL LLDVAPLSLG 
       410        420        430        440        450
IETAGGIMTK LIPRNSTIPT KKSETFSTYA DNQPGVLIQV FEGERTRTKD 
       460        470        480        490        500
NNLLGKFELS GIPPAPRGVP QIDVTFDIDA NGILNVSALE KGTGKSNKIT 
       510        520        530        540        550
ITNDKGRLSK DDIDRMVSEA EKYRADDERE AERVQAKNQL ESYAFTLKNT 
       560        570        580        590        600
INEASFKEKV GEDDAKRLET ASQETIDWLD ASQAASTDEY KDRQKELEGI 
       610        620        630        640 
ANPIMTKFYG AGAGAGPGAG ESGGFPGSMP NSGATGGGED TGPTVEEVD

Length:649

Mass (Da):70,547

Last modified:October 1, 1993 - v3

Checksum:ⁱF4B136759B7D4636

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	620	G → A in CAA30732 (PubMed:2663194).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M97225 Unassigned DNA Translation: AAC37398.1 Z35836 Genomic DNA Translation: CAA84896.1 Z26879 Genomic DNA Translation: CAA81523.1 D90455 Genomic DNA No translation available. M36115 Genomic DNA Translation: AAA35097.1 X07886 Genomic DNA Translation: CAA30732.1 Sequence problems. BK006936 Genomic DNA Translation: DAA07047.1
PIRⁱ	S36753
NCBI Reference Sequences More...RefSeqⁱ	NP_009478.1, NM_001178315.1

Genome annotation databases

EnsemblFungiⁱ	YBL075C; YBL075C; YBL075C
GeneIDⁱ	852203
KEGGⁱ	sce:YBL075C

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P09435	Heat shock protein SSA3		YEAS1		649	UniRef100_P09435
Ssa3p		YEAS8		649
Ssa3p		YEASA		649
Ssa3p		SACCK		649
SSA3p ATPase involved in protein folding and the response to stress		Saccharomyces sp. 'boulardii'		649
+4

Protein	Similar proteins		Species	Score	Length	Source
P09435	Heat shock protein SSA3		YEAS1		649	UniRef90_P09435
Ssa3p		YEAS8		649
Ssa3p		YEASA		649
Ssa3p		SACCK		649
SSA3p ATPase involved in protein folding and the response to stress		Saccharomyces sp. 'boulardii'		649
+12

Protein	Similar proteins		Species	Score	Length	Source
P09435	Heat shock protein SSA2		CANAL		645	UniRef50_P46587
Endoplasmic reticulum chaperone BiP		SCHPO		663
Endoplasmic reticulum chaperone BiP		ECHGR		651
Endoplasmic reticulum chaperone BiP		ECHMU		649
Endoplasmic reticulum chaperone BiP		PICAN		665
+1164

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M97225 Unassigned DNA Translation: AAC37398.1 Z35836 Genomic DNA Translation: CAA84896.1 Z26879 Genomic DNA Translation: CAA81523.1 D90455 Genomic DNA No translation available. M36115 Genomic DNA Translation: AAA35097.1 X07886 Genomic DNA Translation: CAA30732.1 Sequence problems. BK006936 Genomic DNA Translation: DAA07047.1
PIRⁱ	S36753
RefSeqⁱ	NP_009478.1, NM_001178315.1

3D structure databases

ProteinModelPortalⁱ	P09435
SMRⁱ	P09435
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	32627, 138 interactors
DIPⁱ	DIP-2266N
IntActⁱ	P09435, 60 interactors
MINTⁱ	P09435
STRINGⁱ	4932.YBL075C

2D gel databases

UCD-2DPAGEⁱ	P09435

UCD-2DPAGEⁱ

P09435

Proteomic databases

MaxQBⁱ	P09435
PaxDbⁱ	P09435
PRIDEⁱ	P09435

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	YBL075C; YBL075C; YBL075C
GeneIDⁱ	852203
KEGGⁱ	sce:YBL075C

Organism-specific databases

EuPathDBⁱ	FungiDB:YBL075C
SGDⁱ	S000000171 SSA3

Phylogenomic databases

GeneTreeⁱ	ENSGT00920000149300
HOGENOMⁱ	HOG000228135
InParanoidⁱ	P09435
KOⁱ	K03283
OMAⁱ	IANPIMT
OrthoDBⁱ	EOG092C1VPN

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-28967-MONOMER

BioCycⁱ

YEAST:G3O-28967-MONOMER

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P09435

PROⁱ

PR:P09435

Family and domain databases

Gene3Dⁱ	1.20.1270.10, 1 hit 2.60.34.10, 1 hit
InterProⁱ	View protein in InterPro IPR018181 Heat_shock_70_CS IPR029048 HSP70_C_sf IPR029047 HSP70_peptide-bd_sf IPR013126 Hsp_70_fam
PANTHERⁱ	PTHR19375 PTHR19375, 1 hit
Pfamⁱ	View protein in Pfam PF00012 HSP70, 1 hit
PRINTSⁱ	PR00301 HEATSHOCK70
SUPFAMⁱ	SSF100920 SSF100920, 1 hit SSF100934 SSF100934, 1 hit
PROSITEⁱ	View protein in PROSITE PS00297 HSP70_1, 1 hit PS00329 HSP70_2, 1 hit PS01036 HSP70_3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	HSP73_YEAST
Accessionⁱ	P09435Primary (citable) accession number: P09435 Secondary accession number(s): D6VPS7, P18862
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
	Last sequence update:	October 1, 1993
	Last modified:	September 12, 2018
	This is version 179 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Yeast chromosome II
Yeast (Saccharomyces cerevisiae) chromosome II: entries and gene names
SIMILARITY comments
Index of protein domains and families
Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P09435 (HSP73_YEAST)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Heat shock protein SSA3

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Cytosol

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

2D gel databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

2D gel databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ