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UniProtKB - P09391 (GLPG_ECOLI)

Protein

Rhomboid protease GlpG

Gene

glpG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Rhomboid-type serine protease that catalyzes intramembrane proteolysis.2 Publications

Caution

Was originally identified as a repressor of the glycerol-3-phosphate regulon.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains. EC:3.4.21.105

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei201Nucleophile4 Publications1
Active sitei2544 Publications1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • endopeptidase activity Source: EcoCyc
  • identical protein binding Source: IntAct
  • serine-type endopeptidase activity Source: EcoCyc
View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Protease, Serine protease

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:EG10397-MONOMER
MetaCyc:EG10397-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		3.4.21.105 2026

Protein family/group databases

MEROPS protease database

More...MEROPSi		S54.016

Transport Classification Database

More...TCDBi		9.B.104.1.1 the rhomboid protease (rhomboid) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Rhomboid protease GlpG (EC:3.4.21.105)
Alternative name(s):
Intramembrane serine protease
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:glpG
Ordered Locus Names:b3424, JW5687
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...EcoGenei		EG10397 glpG

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 93CytoplasmicCuratedAdd BLAST93
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei94 – 114Helical; Name=1CuratedAdd BLAST21
Topological domaini115 – 141PeriplasmicCuratedAdd BLAST27
Transmembranei142 – 162Helical; Name=2CuratedAdd BLAST21
Topological domaini163 – 168CytoplasmicCurated6
Transmembranei169 – 189Helical; Name=3CuratedAdd BLAST21
Topological domaini190 – 191PeriplasmicCurated2
Transmembranei192 – 212Helical; Name=4CuratedAdd BLAST21
Topological domaini213 – 222CytoplasmicCurated10
Transmembranei223 – 245Helical; Name=5CuratedAdd BLAST23
Topological domaini246 – 249PeriplasmicCurated4
Transmembranei250 – 272Helical; Name=6CuratedAdd BLAST23
Topological domaini273 – 276CytoplasmicCurated4

GO - Cellular componenti

View the complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi154N → A: Reduced catalytic activity. 2 Publications1
Mutagenesisi199G → C: Loss of catalytic activity. 1 Publication1
Mutagenesisi201S → A or C: Loss of catalytic activity. 4 Publications1
Mutagenesisi254H → A or C: Loss of catalytic activity. 3 Publications1

Chemistry databases

Drug and drug target database

More...DrugBanki		DB04147 Lauryl Dimethylamine-N-Oxide

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000875151 – 276Rhomboid protease GlpGAdd BLAST276

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P09391

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P09391

PRoteomics IDEntifications database

More...PRIDEi		P09391

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-9134140,EBI-9134140

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		4262105, 40 interactors

Database of interacting proteins

More...DIPi		DIP-9796N

Protein interaction database and analysis system

More...IntActi		P09391, 3 interactors

Molecular INTeraction database

More...MINTi		P09391

STRING: functional protein association networks

More...STRINGi		316385.ECDH10B_3598

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P09391

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1276
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2IC8X-ray2.10A91-272[»]
2IRVX-ray2.30A/B92-273[»]
2LEPNMR-A1-61[»]
2NRFX-ray2.60A/B91-272[»]
2O7LX-ray2.50A93-272[»]
2XOVX-ray1.65A91-271[»]
2XOWX-ray2.09A92-270[»]
2XTUX-ray1.85A91-271[»]
2XTVX-ray1.70A93-272[»]
3B44X-ray1.70A91-270[»]
3B45X-ray1.90A91-270[»]
3TXTX-ray2.30A92-270[»]
3UBBX-ray2.60A91-272[»]
3ZEBX-ray2.20A92-270[»]
3ZMHX-ray2.30A91-270[»]
3ZMIX-ray2.20A92-270[»]
3ZMJX-ray2.30A92-270[»]
3ZOTX-ray2.40A92-271[»]
4H1DX-ray2.90A92-270[»]
4HDDX-ray1.35A2-74[»]
4NJNX-ray2.40A87-276[»]
4NJPX-ray2.40A87-276[»]
5F5BX-ray2.30A87-276[»]
5F5DX-ray2.50A87-276[»]
5F5GX-ray2.30A87-276[»]
5F5JX-ray2.40A87-276[»]
5F5KX-ray2.40A87-276[»]
5MT6X-ray2.16A91-270[»]
5MT7X-ray2.05A91-271[»]
5MT8X-ray1.95A92-270[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...ProteinModelPortali		P09391

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P09391

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P09391

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The loop between transmembrane domains 5 and 6 is flexible and may readily open to the extracellular side to allow water entry into the active site cavity.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase S54 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG4105EBW Bacteria
COG0705 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000269640

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P09391

KEGG Orthology (KO)

More...KOi		K02441

Database for complete collections of gene phylogenies

More...PhylomeDBi		P09391

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1540.10, 1 hit
3.30.70.2350, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01594 Rhomboid_GlpG, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR038236 GlpG_N_sf
IPR022732 Peptidase_S54_GlpG_N
IPR002610 Peptidase_S54_rhomboid
IPR022764 Peptidase_S54_rhomboid_dom
IPR035952 Rhomboid-like_sf
IPR023662 Rhomboid_protease_GlpG

The PANTHER Classification System

More...PANTHERi		PTHR22936 PTHR22936, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01694 Rhomboid, 1 hit
PF12122 Rhomboid_N, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR04239 rhombo_GlpG, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P09391-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLMITSFANP RVAQAFVDYM ATQGVILTIQ QHNQSDVWLA DESQAERVRA 
        60         70         80         90        100
ELARFLENPA DPRYLAASWQ AGHTGSGLHY RRYPFFAALR ERAGPVTWVM 
       110        120        130        140        150
MIACVVVFIA MQILGDQEVM LWLAWPFDPT LKFEFWRYFT HALMHFSLMH 
       160        170        180        190        200
ILFNLLWWWY LGGAVEKRLG SGKLIVITLI SALLSGYVQQ KFSGPWFGGL 
       210        220        230        240        250
SGVVYALMGY VWLRGERDPQ SGIYLQRGLI IFALIWIVAG WFDLFGMSMA 
       260        270 
NGAHIAGLAV GLAMAFVDSL NARKRK
Length:276
Mass (Da):31,307
Last modified:October 11, 2004 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6F67374E609968FC
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA58222 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti51 – 52EL → DV in AAA23890 (PubMed:3045764).Curated2
Sequence conflicti51 – 52EL → DV in CAA30398 (PubMed:3045764).Curated2
Sequence conflicti51 – 52EL → DV in AAC28166 (PubMed:8955387).Curated2
Sequence conflicti51 – 52EL → DV in AAA58222 (PubMed:9278503).Curated2
Sequence conflicti178 – 179TL → RS in AAA23890 (PubMed:3045764).Curated2
Sequence conflicti178 – 179TL → RS in CAA30398 (PubMed:3045764).Curated2
Sequence conflicti193S → T in AAA23890 (PubMed:3045764).Curated1
Sequence conflicti193S → T in CAA30398 (PubMed:3045764).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M54940 Genomic DNA Translation: AAA23890.1
X07520 Genomic DNA Translation: CAA30398.1
M96795 Genomic DNA Translation: AAC28166.1
U18997 Genomic DNA Translation: AAA58222.1 Different initiation.
U00096 Genomic DNA Translation: AAT48182.1
AP009048 Genomic DNA Translation: BAE77868.1

Protein sequence database of the Protein Information Resource

More...PIRi		C65138 BVECGG

NCBI Reference Sequences

More...RefSeqi		WP_000928723.1, NZ_LN832404.1
YP_026220.1, NC_000913.3

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAT48182; AAT48182; b3424
BAE77868; BAE77868; BAE77868

Database of genes from NCBI RefSeq genomes

More...GeneIDi		947936

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW5687
eco:b3424

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.3305

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M54940 Genomic DNA Translation: AAA23890.1
X07520 Genomic DNA Translation: CAA30398.1
M96795 Genomic DNA Translation: AAC28166.1
U18997 Genomic DNA Translation: AAA58222.1 Different initiation.
U00096 Genomic DNA Translation: AAT48182.1
AP009048 Genomic DNA Translation: BAE77868.1
PIRiC65138 BVECGG
RefSeqiWP_000928723.1, NZ_LN832404.1
YP_026220.1, NC_000913.3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2IC8X-ray2.10A91-272[»]
2IRVX-ray2.30A/B92-273[»]
2LEPNMR-A1-61[»]
2NRFX-ray2.60A/B91-272[»]
2O7LX-ray2.50A93-272[»]
2XOVX-ray1.65A91-271[»]
2XOWX-ray2.09A92-270[»]
2XTUX-ray1.85A91-271[»]
2XTVX-ray1.70A93-272[»]
3B44X-ray1.70A91-270[»]
3B45X-ray1.90A91-270[»]
3TXTX-ray2.30A92-270[»]
3UBBX-ray2.60A91-272[»]
3ZEBX-ray2.20A92-270[»]
3ZMHX-ray2.30A91-270[»]
3ZMIX-ray2.20A92-270[»]
3ZMJX-ray2.30A92-270[»]
3ZOTX-ray2.40A92-271[»]
4H1DX-ray2.90A92-270[»]
4HDDX-ray1.35A2-74[»]
4NJNX-ray2.40A87-276[»]
4NJPX-ray2.40A87-276[»]
5F5BX-ray2.30A87-276[»]
5F5DX-ray2.50A87-276[»]
5F5GX-ray2.30A87-276[»]
5F5JX-ray2.40A87-276[»]
5F5KX-ray2.40A87-276[»]
5MT6X-ray2.16A91-270[»]
5MT7X-ray2.05A91-271[»]
5MT8X-ray1.95A92-270[»]
ProteinModelPortaliP09391
SMRiP09391
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262105, 40 interactors
DIPiDIP-9796N
IntActiP09391, 3 interactors
MINTiP09391
STRINGi316385.ECDH10B_3598

Chemistry databases

BindingDBiP09391
DrugBankiDB04147 Lauryl Dimethylamine-N-Oxide

Protein family/group databases

MEROPSiS54.016
TCDBi9.B.104.1.1 the rhomboid protease (rhomboid) family

Proteomic databases

jPOSTiP09391
PaxDbiP09391
PRIDEiP09391

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48182; AAT48182; b3424
BAE77868; BAE77868; BAE77868
GeneIDi947936
KEGGiecj:JW5687
eco:b3424
PATRICifig|1411691.4.peg.3305

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB0392
EcoGeneiEG10397 glpG

Phylogenomic databases

eggNOGiENOG4105EBW Bacteria
COG0705 LUCA
HOGENOMiHOG000269640
InParanoidiP09391
KOiK02441
PhylomeDBiP09391

Enzyme and pathway databases

BioCyciEcoCyc:EG10397-MONOMER
MetaCyc:EG10397-MONOMER
BRENDAi3.4.21.105 2026

Miscellaneous databases

EvolutionaryTraceiP09391

Protein Ontology

More...PROi		PR:P09391

Family and domain databases

Gene3Di1.20.1540.10, 1 hit
3.30.70.2350, 1 hit
HAMAPiMF_01594 Rhomboid_GlpG, 1 hit
InterProiView protein in InterPro
IPR038236 GlpG_N_sf
IPR022732 Peptidase_S54_GlpG_N
IPR002610 Peptidase_S54_rhomboid
IPR022764 Peptidase_S54_rhomboid_dom
IPR035952 Rhomboid-like_sf
IPR023662 Rhomboid_protease_GlpG
PANTHERiPTHR22936 PTHR22936, 1 hit
PfamiView protein in Pfam
PF01694 Rhomboid, 1 hit
PF12122 Rhomboid_N, 1 hit
TIGRFAMsiTIGR04239 rhombo_GlpG, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGLPG_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P09391
Secondary accession number(s): P76691, Q2M788, Q6BF32
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: October 11, 2004
Last modified: January 16, 2019
This is version 154 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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