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UniProtKB - P09323 (PTW3C_ECOLI)

Entry version 181 (02 Dec 2020)
Sequence version 1 (01 Jul 1989)
Previous versions | rss
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Protein

PTS system N-acetylglucosamine-specific EIICBA component

Gene

nagE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (PubMed:4919472). This system is involved in N-acetylglucosamine transport (PubMed:4919472). It can also transport and phosphorylate the antibiotic streptozotocin (PubMed:161156). Could play a significant role in the recycling of peptidoglycan (PubMed:19617367).1 Publication3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

P-chloromercuribenzoate inhibits the accumulation of both N-acetyl-D-glucosamine and antibiotic streptozotocin (2-deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose). N-acetyl-D-glucosamine is a competitive inhibitor for the uptake of streptozotocin.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei412Phosphocysteine intermediate; for EIIB activityPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi554ZincBy similarity1
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei554Important for phospho-donor activityBy similarity1
Active sitei569Tele-phosphohistidine intermediate; for EIIA activityPROSITE-ProRule annotation1 Publication1
Metal bindingi569ZincBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processPhosphotransferase system, Sugar transport, Transport
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:NAGE-MONOMER
MetaCyc:NAGE-MONOMER

Protein family/group databases

Transport Classification Database

More...TCDBi		4.A.1.1.2, the pts glucose-glucoside (glc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PTS system N-acetylglucosamine-specific EIICBA component1 Publication
Alternative name(s):
EIICBA-Nag1 Publication
Short name:
EII-Nag1 Publication
Including the following 3 domains:
N-acetylglucosamine permease IIC component1 Publication
Alternative name(s):
PTS system N-acetylglucosamine-specific EIIC component1 Publication
N-acetylglucosamine-specific phosphotransferase enzyme IIB component1 Publication (EC:2.7.1.1931 Publication)
Alternative name(s):
PTS system N-acetylglucosamine-specific EIIB component1 Publication
N-acetylglucosamine-specific phosphotransferase enzyme IIA component1 Publication
Alternative name(s):
PTS system N-acetylglucosamine-specific EIIA component1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nagE1 Publication
Synonyms:pstN
Ordered Locus Names:b0679, JW0665
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei16 – 36HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei38 – 58HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei70 – 90HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei92 – 112HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei132 – 152HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei159 – 179HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei192 – 212HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei232 – 252HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei260 – 280HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei282 – 302HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei303 – 323HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei339 – 359HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells lacking nagE and nagA reduce by 50% the amount of GlcNAc6P. Together with the mutations of the genes of the peptidoglycan recycling pathway (ampG, anmK, murQ, nagK and nagZ), the accumulation of GlcNAc6P is eliminated.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001864751 – 648PTS system N-acetylglucosamine-specific EIICBA componentAdd BLAST648

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei412Phosphocysteine; by EIIABy similarityCurated1
Modified residuei569Phosphohistidine; by HPrBy similarityCurated1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P09323

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P09323

PRoteomics IDEntifications database

More...PRIDEi		P09323

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induced by N-acetylglucosamine-6-phosphate and repressed by NagC.2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		4261209, 24 interactors

STRING: functional protein association networks

More...STRINGi		511145.b0679

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P09323

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 371PTS EIIC type-1PROSITE-ProRule annotationAdd BLAST371
Domaini390 – 472PTS EIIB type-1PROSITE-ProRule annotationAdd BLAST83
Domaini517 – 621PTS EIIA type-1PROSITE-ProRule annotationAdd BLAST105

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PTS EIIC type-1 domain forms the PTS system translocation channel and contains the specific substrate-binding site.PROSITE-ProRule annotation
The PTS EIIB type-1 domain is phosphorylated by phospho-EIIA on a cysteinyl residue. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the PTS EIIC type-1 domain.PROSITE-ProRule annotation
The PTS EIIA type-1 domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the PTS EIIB type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG1263, Bacteria
COG1264, Bacteria
COG2190, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_012312_1_3_6

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P09323

Database for complete collections of gene phylogenies

More...PhylomeDBi		P09323

Family and domain databases

Conserved Domains Database

More...CDDi		cd00212, PTS_IIB_glc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.70.70.10, 1 hit
3.30.1360.60, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011055, Dup_hybrid_motif
IPR036878, Glu_permease_IIB
IPR018113, PTrfase_EIIB_Cys
IPR001127, PTS_EIIA_1_perm
IPR003352, PTS_EIIC
IPR013013, PTS_EIIC_1
IPR001996, PTS_IIB_1
IPR010974, PTS_IIBC_nag

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00358, PTS_EIIA_1, 1 hit
PF00367, PTS_EIIB, 1 hit
PF02378, PTS_EIIC, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF51261, SSF51261, 1 hit
SSF55604, SSF55604, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00826, EIIB_glc, 1 hit
TIGR00830, PTBA, 1 hit
TIGR01998, PTS-II-BC-nag, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51093, PTS_EIIA_TYPE_1, 1 hit
PS00371, PTS_EIIA_TYPE_1_HIS, 1 hit
PS51098, PTS_EIIB_TYPE_1, 1 hit
PS01035, PTS_EIIB_TYPE_1_CYS, 1 hit
PS51103, PTS_EIIC_TYPE_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P09323-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNILGFFQRL GRALQLPIAV LPVAALLLRF GQPDLLNVAF IAQAGGAIFD 
        60         70         80         90        100
NLALIFAIGV ASSWSKDSAG AAALAGAVGY FVLTKAMVTI NPEINMGVLA 
       110        120        130        140        150
GIITGLVGGA AYNRWSDIKL PDFLSFFGGK RFVPIATGFF CLVLAAIFGY 
       160        170        180        190        200
VWPPVQHAIH AGGEWIVSAG ALGSGIFGFI NRLLIPTGLH QVLNTIAWFQ 
       210        220        230        240        250
IGEFTNAAGT VFHGDINRFY AGDGTAGMFM SGFFPIMMFG LPGAALAMYF 
       260        270        280        290        300
AAPKERRPMV GGMLLSVAVT AFLTGVTEPL EFLFMFLAPL LYLLHALLTG 
       310        320        330        340        350
ISLFVATLLG IHAGFSFSAG AIDYALMYNL PAASQNVWML LVMGVIFFAI 
       360        370        380        390        400
YFVVFSLVIR MFNLKTPGRE DKEDEIVTEE ANSNTEEGLT QLATNYIAAV 
       410        420        430        440        450
GGTDNLKAID ACITRLRLTV ADSARVNDTM CKRLGASGVV KLNKQTIQVI 
       460        470        480        490        500
VGAKAESIGD AMKKVVARGP VAAASAEATP ATAAPVAKPQ AVPNAVSIAE 
       510        520        530        540        550
LVSPITGDVV ALDQVPDEAF ASKAVGDGVA VKPTDKIVVS PAAGTIVKIF 
       560        570        580        590        600
NTNHAFCLET EKGAEIVVHM GIDTVALEGK GFKRLVEEGA QVSAGQPILE 
       610        620        630        640 
MDLDYLNANA RSMISPVVCS NIDDFSGLII KAQGHIVAGQ TPLYEIKK
Length:648
Mass (Da):68,347
Last modified:July 1, 1989 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1E24C97CFCBBAA59
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M19284 Genomic DNA Translation: AAA24192.1
U00096 Genomic DNA Translation: AAC73773.1
AP009048 Genomic DNA Translation: BAA35327.1

Protein sequence database of the Protein Information Resource

More...PIRi		B29895, WQEC2N

NCBI Reference Sequences

More...RefSeqi		NP_415205.1, NC_000913.3
WP_001023093.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC73773; AAC73773; b0679
BAA35327; BAA35327; BAA35327

Database of genes from NCBI RefSeq genomes

More...GeneIDi		945292

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW0665
eco:b0679

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.1598

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19284 Genomic DNA Translation: AAA24192.1
U00096 Genomic DNA Translation: AAC73773.1
AP009048 Genomic DNA Translation: BAA35327.1
PIRiB29895, WQEC2N
RefSeqiNP_415205.1, NC_000913.3
WP_001023093.1, NZ_LN832404.1

3D structure databases

SMRiP09323
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi4261209, 24 interactors
STRINGi511145.b0679

Protein family/group databases

TCDBi4.A.1.1.2, the pts glucose-glucoside (glc) family

Proteomic databases

jPOSTiP09323
PaxDbiP09323
PRIDEiP09323

Genome annotation databases

EnsemblBacteriaiAAC73773; AAC73773; b0679
BAA35327; BAA35327; BAA35327
GeneIDi945292
KEGGiecj:JW0665
eco:b0679
PATRICifig|1411691.4.peg.1598

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB0629

Phylogenomic databases

eggNOGiCOG1263, Bacteria
COG1264, Bacteria
COG2190, Bacteria
HOGENOMiCLU_012312_1_3_6
InParanoidiP09323
PhylomeDBiP09323

Enzyme and pathway databases

BioCyciEcoCyc:NAGE-MONOMER
MetaCyc:NAGE-MONOMER

Miscellaneous databases

Protein Ontology

More...PROi		PR:P09323

Family and domain databases

CDDicd00212, PTS_IIB_glc, 1 hit
Gene3Di2.70.70.10, 1 hit
3.30.1360.60, 1 hit
InterProiView protein in InterPro
IPR011055, Dup_hybrid_motif
IPR036878, Glu_permease_IIB
IPR018113, PTrfase_EIIB_Cys
IPR001127, PTS_EIIA_1_perm
IPR003352, PTS_EIIC
IPR013013, PTS_EIIC_1
IPR001996, PTS_IIB_1
IPR010974, PTS_IIBC_nag
PfamiView protein in Pfam
PF00358, PTS_EIIA_1, 1 hit
PF00367, PTS_EIIB, 1 hit
PF02378, PTS_EIIC, 1 hit
SUPFAMiSSF51261, SSF51261, 1 hit
SSF55604, SSF55604, 1 hit
TIGRFAMsiTIGR00826, EIIB_glc, 1 hit
TIGR00830, PTBA, 1 hit
TIGR01998, PTS-II-BC-nag, 1 hit
PROSITEiView protein in PROSITE
PS51093, PTS_EIIA_TYPE_1, 1 hit
PS00371, PTS_EIIA_TYPE_1_HIS, 1 hit
PS51098, PTS_EIIB_TYPE_1, 1 hit
PS01035, PTS_EIIB_TYPE_1_CYS, 1 hit
PS51103, PTS_EIIC_TYPE_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPTW3C_ECOLI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P09323
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: December 2, 2020
This is version 181 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome
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