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UniProtKB - P09210 (GSTA2_HUMAN)

Entry version 205 (13 Nov 2019)
Sequence version 4 (20 Feb 2007)
Previous versions | rss
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Protein

Glutathione S-transferase A2

Gene

GSTA2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei9Glutathione1 Publication1
Binding sitei45Glutathione1 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MetaCyc:HS01846-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.5.1.18 2681

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-156590 Glutathione conjugation
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

SABIO-RK: Biochemical Reaction Kinetics Database

More...SABIO-RKi		P09210

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glutathione S-transferase A2 (EC:2.5.1.18)
Alternative name(s):
GST HA subunit 2
GST class-alpha member 2
GST-gamma
GSTA2-2
GTH2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GSTA2
Synonyms:GST2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:4627 GSTA2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		138360 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P09210

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		2939

Open Targets

More...OpenTargetsi		ENSG00000244067

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA29017

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P09210

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...ChEMBLi		CHEMBL2241

Drug and drug target database

More...DrugBanki		DB14001 alpha-Tocopherol succinate
DB00993 Azathioprine
DB01008 Busulfan
DB00608 Chloroquine
DB00636 Clofibrate
DB14002 D-alpha-Tocopherol acetate
DB00903 Etacrynic acid
DB00143 Glutathione
DB00163 Vitamin E

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		GSTA2

Domain mapping of disease mutations (DMDM)

More...DMDMi		126302551

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001857842 – 222Glutathione S-transferase A2Add BLAST221

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei4N6-succinyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P09210

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P09210

MaxQB - The MaxQuant DataBase

More...MaxQBi		P09210

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P09210

PeptideAtlas

More...PeptideAtlasi		P09210

PRoteomics IDEntifications database

More...PRIDEi		P09210

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		52206

2D gel databases

REPRODUCTION-2DPAGE

More...REPRODUCTION-2DPAGEi		IPI00745233

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P09210

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P09210

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Liver.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000244067 Expressed in 53 organ(s), highest expression level in body of pancreas

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P09210 baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA004342
HPA048934
HPA053817

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer or heterodimer of GSTA1 and GSTA2.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		109194, 5 interactors

Protein interaction database and analysis system

More...IntActi		P09210, 5 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000420168

Chemistry databases

BindingDB database of measured binding affinities

More...BindingDBi		P09210

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1222
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P09210

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P09210

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 83GST N-terminalAdd BLAST81
Domaini85 – 207GST C-terminalAdd BLAST123

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni54 – 55Glutathione binding1 Publication2
Regioni67 – 68Glutathione binding1 Publication2

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GST superfamily. Alpha family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1695 Eukaryota
ENOG4111VAU LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000164034

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000115734

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P09210

KEGG Orthology (KO)

More...KOi		K00799

Identification of Orthologs from Complete Genome Data

More...OMAi		CPPAEKD

Database of Orthologous Groups

More...OrthoDBi		1162336at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P09210

TreeFam database of animal gene trees

More...TreeFami		TF105321

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.40.30.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR040079 Glutathione_S-Trfase
IPR004045 Glutathione_S-Trfase_N
IPR003080 GST_alpha
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14497 GST_C_3, 1 hit
PF02798 GST_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01266 GSTRNSFRASEA

Structure-Function Linkage Database

More...SFLDi		SFLDS00019 Glutathione_Transferase_(cytos, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P09210-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEKPKLHYS NIRGRMESIR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL 
        60         70         80         90        100
MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKEKA LIDMYIEGIA 
       110        120        130        140        150
DLGEMILLLP FSQPEEQDAK LALIQEKTKN RYFPAFEKVL KSHGQDYLVG 
       160        170        180        190        200
NKLSRADIHL VELLYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP 
       210        220 
GSPRKPPMDE KSLEESRKIF RF
Length:222
Mass (Da):25,664
Last modified:February 20, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2823565A693A30AC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti10 – 12SNI → FNA AA sequence (PubMed:8431482).Curated3
Sequence conflicti12I → T in CAA46642 (PubMed:1497629).Curated1
Sequence conflicti19I → T AA sequence (PubMed:8431482).Curated1
Sequence conflicti89K → R AA sequence (PubMed:8431482).Curated1
Sequence conflicti128T → I AA sequence (PubMed:8431482).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_014495110P → S. Corresponds to variant dbSNP:rs2234951Ensembl.1
Natural variantiVAR_012205112S → TCombined sources3 PublicationsCorresponds to variant dbSNP:rs2180314Ensembl.1
Natural variantiVAR_014496149V → A. Corresponds to variant dbSNP:rs2266631Ensembl.1
Natural variantiVAR_012206210E → A3 PublicationsCorresponds to variant dbSNP:rs6577Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
M16594 mRNA Translation: AAA52616.1
S45640
, S45627, S45629, S45636, S45637, S45639 Genomic DNA Translation: AAB23672.1
X65727
, X65728, X65729, X65730, X65731, X65732 Genomic DNA Translation: CAA46642.1
AL109918 Genomic DNA No translation available.
BC002895 mRNA Translation: AAH02895.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS4944.1

Protein sequence database of the Protein Information Resource

More...PIRi		S24330
S29658

NCBI Reference Sequences

More...RefSeqi		NP_000837.3, NM_000846.4
XP_011512834.1, XM_011514532.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000493422; ENSP00000420168; ENSG00000244067

Database of genes from NCBI RefSeq genomes

More...GeneIDi		2939

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:2939

UCSC genome browser

More...UCSCi		uc003pay.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M16594 mRNA Translation: AAA52616.1
S45640
, S45627, S45629, S45636, S45637, S45639 Genomic DNA Translation: AAB23672.1
X65727
, X65728, X65729, X65730, X65731, X65732 Genomic DNA Translation: CAA46642.1
AL109918 Genomic DNA No translation available.
BC002895 mRNA Translation: AAH02895.1
CCDSiCCDS4944.1
PIRiS24330
S29658
RefSeqiNP_000837.3, NM_000846.4
XP_011512834.1, XM_011514532.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1AGSX-ray2.50A/B2-222[»]
2VCTX-ray2.10A/B/C/D/E/F/G/H1-222[»]
2WJUX-ray2.30A/B/C/D/E/F/G/H1-222[»]
4ACSX-ray2.10A/B/C/D1-221[»]
SMRiP09210
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi109194, 5 interactors
IntActiP09210, 5 interactors
STRINGi9606.ENSP00000420168

Chemistry databases

BindingDBiP09210
ChEMBLiCHEMBL2241
DrugBankiDB14001 alpha-Tocopherol succinate
DB00993 Azathioprine
DB01008 Busulfan
DB00608 Chloroquine
DB00636 Clofibrate
DB14002 D-alpha-Tocopherol acetate
DB00903 Etacrynic acid
DB00143 Glutathione
DB00163 Vitamin E

PTM databases

iPTMnetiP09210
PhosphoSitePlusiP09210

Polymorphism and mutation databases

BioMutaiGSTA2
DMDMi126302551

2D gel databases

REPRODUCTION-2DPAGEiIPI00745233

Proteomic databases

jPOSTiP09210
MassIVEiP09210
MaxQBiP09210
PaxDbiP09210
PeptideAtlasiP09210
PRIDEiP09210
ProteomicsDBi52206

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		2939

Genome annotation databases

EnsembliENST00000493422; ENSP00000420168; ENSG00000244067
GeneIDi2939
KEGGihsa:2939
UCSCiuc003pay.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		2939
DisGeNETi2939

GeneCards: human genes, protein and diseases

More...GeneCardsi		GSTA2
HGNCiHGNC:4627 GSTA2
HPAiHPA004342
HPA048934
HPA053817
MIMi138360 gene
neXtProtiNX_P09210
OpenTargetsiENSG00000244067
PharmGKBiPA29017

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1695 Eukaryota
ENOG4111VAU LUCA
GeneTreeiENSGT00940000164034
HOGENOMiHOG000115734
InParanoidiP09210
KOiK00799
OMAiCPPAEKD
OrthoDBi1162336at2759
PhylomeDBiP09210
TreeFamiTF105321

Enzyme and pathway databases

BioCyciMetaCyc:HS01846-MONOMER
BRENDAi2.5.1.18 2681
ReactomeiR-HSA-156590 Glutathione conjugation
R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
SABIO-RKiP09210

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		GSTA2 human
EvolutionaryTraceiP09210

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		GSTA2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		2939
PharosiP09210

Protein Ontology

More...PROi		PR:P09210

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000244067 Expressed in 53 organ(s), highest expression level in body of pancreas
ExpressionAtlasiP09210 baseline and differential

Family and domain databases

Gene3Di3.40.30.10, 1 hit
InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR040079 Glutathione_S-Trfase
IPR004045 Glutathione_S-Trfase_N
IPR003080 GST_alpha
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF14497 GST_C_3, 1 hit
PF02798 GST_N, 1 hit
PRINTSiPR01266 GSTRNSFRASEA
SFLDiSFLDS00019 Glutathione_Transferase_(cytos, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGSTA2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P09210
Secondary accession number(s): Q12759, Q16491, Q9NTY6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: February 20, 2007
Last modified: November 13, 2019
This is version 205 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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