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UniProtKB - P09001 (RM03_HUMAN)

Entry version 174 (18 Sep 2019)
Sequence version 1 (01 Nov 1988)
Previous versions | rss
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Protein

39S ribosomal protein L3, mitochondrial

Gene

MRPL3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-5368286 Mitochondrial translation initiation
R-HSA-5389840 Mitochondrial translation elongation
R-HSA-5419276 Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
39S ribosomal protein L3, mitochondrial
Short name:
L3mt
Short name:
MRP-L3
Alternative name(s):
Mitochondrial large ribosomal subunit protein uL3m1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MRPL3
Synonyms:MRL3, RPML3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:10379 MRPL3

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		607118 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P09001

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Combined oxidative phosphorylation deficiency 9 (COXPD9)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA mitochondrial disease characterized by failure to thrive, poor feeding, hypertrophic cardiomyopathy, hepatomegaly, and psychomotor retardation. Death in infancy has been observed in some cases.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_066676317P → R in COXPD9. 1 PublicationCorresponds to variant dbSNP:rs387906962EnsemblClinVar.1

Keywords - Diseasei

Disease mutation, Primary mitochondrial disease

Organism-specific databases

DisGeNET

More...DisGeNETi		11222

MalaCards human disease database

More...MalaCardsi		MRPL3
MIMi614582 phenotype

Open Targets

More...OpenTargetsi		ENSG00000114686

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...Orphaneti		319509 Combined oxidative phosphorylation defect type 9

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA30960

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MRPL3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 40MitochondrionCombined sourcesAdd BLAST40
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000007725341 – 34839S ribosomal protein L3, mitochondrialAdd BLAST308

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P09001

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P09001

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P09001

MaxQB - The MaxQuant DataBase

More...MaxQBi		P09001

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P09001

PeptideAtlas

More...PeptideAtlasi		P09001

PRoteomics IDEntifications database

More...PRIDEi		P09001

ProteomicsDB human proteome resource

More...ProteomicsDBi		52183

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P09001

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P09001

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P09001

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000114686 Expressed in 238 organ(s), highest expression level in secondary oocyte

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P09001 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P09001 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA043665
HPA060132

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:28892042, PubMed:25838379, PubMed:25278503). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.

3 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		116390, 73 interactors

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P09001

Protein interaction database and analysis system

More...IntActi		P09001, 45 interactors

Molecular INTeraction database

More...MINTi		P09001

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000264995

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1348
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P09001

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uL3 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3141 Eukaryota
COG0087 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011422

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000100369

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P09001

KEGG Orthology (KO)

More...KOi		K02906

Database of Orthologous Groups

More...OrthoDBi		1269775at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P09001

TreeFam database of animal gene trees

More...TreeFami		TF105634

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000597 Ribosomal_L3
IPR019927 Ribosomal_L3_bac/org-type
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf

The PANTHER Classification System

More...PANTHERi		PTHR11229 PTHR11229, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00297 Ribosomal_L3, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50447 SSF50447, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR03625 L3_bact, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P09001-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGWRLLTQV GAQVLGRLGD GLGAALGPGN RTHIWLFVRG LHGKSGTWWD 
        60         70         80         90        100
EHLSEENVPF IKQLVSDEDK AQLASKLCPL KDEPWPIHPW EPGSFRVGLI 
       110        120        130        140        150
ALKLGMMPLW TKDGQKHVVT LLQVQDCHVL KYTSKENCNG KMATLSVGGK 
       160        170        180        190        200
TVSRFRKATS ILEFYRELGL PPKQTVKIFN ITDNAAIKPG TPLYAAHFRP 
       210        220        230        240        250
GQYVDVTAKT IGKGFQGVMK RWGFKGQPAT HGQTKTHRRP GAVATGDIGR 
       260        270        280        290        300
VWPGTKMPGK MGNIYRTEYG LKVWRINTKH NIIYVNGSVP GHKNCLVKVK 
       310        320        330        340 
DSKLPAYKDL GKNLPFPTYF PDGDEEELPE DLYDENVCQP GAPSITFA
Length:348
Mass (Da):38,633
Last modified:November 1, 1988 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6DE6B5BD6BD72E32
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y9G6H0Y9G6_HUMAN
39S ribosomal protein L3, mitochond...
MRPL3
363Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RC14D6RC14_HUMAN
39S ribosomal protein L3, mitochond...
MRPL3
155Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7ETU7E7ETU7_HUMAN
39S ribosomal protein L3, mitochond...
MRPL3
375Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PF06E9PF06_HUMAN
39S ribosomal protein L3, mitochond...
MRPL3
176Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RBQ5D6RBQ5_HUMAN
39S ribosomal protein L3, mitochond...
MRPL3
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_020108261M → T. Corresponds to variant dbSNP:rs2291381EnsemblClinVar.1
Natural variantiVAR_066676317P → R in COXPD9. 1 PublicationCorresponds to variant dbSNP:rs387906962EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X06323 mRNA Translation: CAA29639.1
CR456720 mRNA Translation: CAG33001.1
CH471052 Genomic DNA Translation: EAW79209.1
BC003375 mRNA Translation: AAH03375.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS3071.1

Protein sequence database of the Protein Information Resource

More...PIRi		A27294 R5HUL3

NCBI Reference Sequences

More...RefSeqi		NP_009139.1, NM_007208.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000264995; ENSP00000264995; ENSG00000114686

Database of genes from NCBI RefSeq genomes

More...GeneIDi		11222

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:11222

UCSC genome browser

More...UCSCi		uc003eoh.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X06323 mRNA Translation: CAA29639.1
CR456720 mRNA Translation: CAG33001.1
CH471052 Genomic DNA Translation: EAW79209.1
BC003375 mRNA Translation: AAH03375.1
CCDSiCCDS3071.1
PIRiA27294 R5HUL3
RefSeqiNP_009139.1, NM_007208.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J7Yelectron microscopy3.40E1-348[»]
3J9Melectron microscopy3.50E1-348[»]
5OOLelectron microscopy3.06E1-348[»]
5OOMelectron microscopy3.03E1-348[»]
6NU2electron microscopy3.90E45-348[»]
6NU3electron microscopy4.40E1-348[»]
SMRiP09001
ModBaseiSearch...

Protein-protein interaction databases

BioGridi116390, 73 interactors
CORUMiP09001
IntActiP09001, 45 interactors
MINTiP09001
STRINGi9606.ENSP00000264995

PTM databases

iPTMnetiP09001
PhosphoSitePlusiP09001
SwissPalmiP09001

Polymorphism and mutation databases

BioMutaiMRPL3

Proteomic databases

EPDiP09001
jPOSTiP09001
MassIVEiP09001
MaxQBiP09001
PaxDbiP09001
PeptideAtlasiP09001
PRIDEiP09001
ProteomicsDBi52183

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		11222
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000264995; ENSP00000264995; ENSG00000114686
GeneIDi11222
KEGGihsa:11222
UCSCiuc003eoh.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		11222
DisGeNETi11222

GeneCards: human genes, protein and diseases

More...GeneCardsi		MRPL3
HGNCiHGNC:10379 MRPL3
HPAiHPA043665
HPA060132
MalaCardsiMRPL3
MIMi607118 gene
614582 phenotype
neXtProtiNX_P09001
OpenTargetsiENSG00000114686
Orphaneti319509 Combined oxidative phosphorylation defect type 9
PharmGKBiPA30960

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3141 Eukaryota
COG0087 LUCA
GeneTreeiENSGT00390000011422
HOGENOMiHOG000100369
InParanoidiP09001
KOiK02906
OrthoDBi1269775at2759
PhylomeDBiP09001
TreeFamiTF105634

Enzyme and pathway databases

ReactomeiR-HSA-5368286 Mitochondrial translation initiation
R-HSA-5389840 Mitochondrial translation elongation
R-HSA-5419276 Mitochondrial translation termination

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		MRPL3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		11222

Pharos

More...Pharosi		P09001

Protein Ontology

More...PROi		PR:P09001

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000114686 Expressed in 238 organ(s), highest expression level in secondary oocyte
ExpressionAtlasiP09001 baseline and differential
GenevisibleiP09001 HS

Family and domain databases

InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019927 Ribosomal_L3_bac/org-type
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR11229 PTHR11229, 1 hit
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
TIGRFAMsiTIGR03625 L3_bact, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRM03_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P09001
Secondary accession number(s): Q6IBT2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1988
Last modified: September 18, 2019
This is version 174 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  7. Ribosomal proteins
    Ribosomal proteins families and list of entries
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