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UniProtKB - P08970 (SUHW_DROME)

Entry version 196 (10 Feb 2021)
Sequence version 2 (15 Aug 2003)
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Protein

Protein suppressor of hairy wing

Gene

su(Hw)

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the gypsy chromatin insulator complex which is required for the function of the gypsy chromatin insulator and other endogenous chromatin insulators. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them and can also buffer transgenes from position effect variegation (PEV). Insulators are proposed to structure the chromatin fiber into independent domains of differing transcriptional potential by promoting the formation of distinct chromatin loops. This chromatin looping may involve the formation of insulator bodies, where homotypic interactions between individual subunits of the insulator complex could promote the clustering of widely spaced insulators at the nuclear periphery. Within the gypsy insulator complex, this protein binds specifically to a region of the gypsy element located 3' of the 5' long terminal repeat (LTR), and may also mediate interaction with other endogenous insulators at sites distinct from those recognized by Cp190.8 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri220 – 242C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri290 – 313C2H2-type 2PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri319 – 341C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 366C2H2-type 4PROSITE-ProRule annotationAdd BLAST19
Zinc fingeri380 – 402C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri441 – 463C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri469 – 491C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri497 – 519C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri523 – 545C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri553 – 577C2H2-type 11PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri596 – 619C2H2-type 12PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator, DNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		P08970

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein suppressor of hairy wing
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:su(Hw)
ORF Names:CG8573
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0003567, su(Hw)

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000470531 – 941Protein suppressor of hairy wingAdd BLAST941

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei186Phosphothreonine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P08970

PRoteomics IDEntifications database

More...PRIDEi		P08970

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P08970

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed in all stages of development.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0003567, Expressed in embryo and 75 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P08970, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P08970, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the gypsy chromatin insulator complex, composed of Cp190, mod(mdg4) and su(Hw) (PubMed:7664338, PubMed:11350941, PubMed:11416154, PubMed:15574329). The gypsy chromatin insulator complex interacts with Topors via mod(mdg4) and su(Hw) (PubMed:16209949). Upon ecdysone stimulation, interacts with Nup98 (PubMed:28366641).

6 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		66816, 53 interactors

Database of interacting proteins

More...DIPi		DIP-17895N

Protein interaction database and analysis system

More...IntActi		P08970, 21 interactors

Molecular INTeraction database

More...MINTi		P08970

STRING: functional protein association networks

More...STRINGi		7227.FBpp0082404

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P08970

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni760 – 860Interaction with mod(mdg4)Add BLAST101

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi155 – 202Asp/Glu-rich (acidic)Add BLAST48

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri220 – 242C2H2-type 1; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri290 – 313C2H2-type 2PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri319 – 341C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 366C2H2-type 4PROSITE-ProRule annotationAdd BLAST19
Zinc fingeri380 – 402C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri413 – 435C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri441 – 463C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri469 – 491C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri497 – 519C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri523 – 545C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri553 – 577C2H2-type 11PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri596 – 619C2H2-type 12PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000166978

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_013489_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P08970

Identification of Orthologs from Complete Genome Data

More...OMAi		KMDHYVL

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P08970

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P08970-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSASKEGKEK KGKLLGVENI SPPKDKRPAT RMKLLNDVGA GEDSEASTTT 
        60         70         80         90        100
TTSRTPSNKQ EKRGSVAGSR IKILNEEILG TPKTEKRGAT KSTAPAASTV 
       110        120        130        140        150
KILNEKKTPS ATVTAVETTK IKTSPSKRKK MEHYVLQAVK SENTKADTTV 
       160        170        180        190        200
TVVTEEDDTI DFILADDEEV VPGRIENNNG QEIVVTEDDE DLGEDGDEDG 
       210        220        230        240        250
EDSSGKGNSS QTKIKEIVEH VCGKCYKTFR RVQSLKKHLE FCRYDSGYHL 
       260        270        280        290        300
RKADMLKNLE KIEKDAVVME KKDICFCCSE SYDTFHLGHI NCPDCPKSFK 
       310        320        330        340        350
TQTSYERHIF ITHSEFSDFP CSICNANLRS EALLALHEEQ HKSRGKPYAC 
       360        370        380        390        400
KICGKDFTRS YHLKRHQKYS SCSSNETDTM SCKVCDRVFY RLDNLRSHLK 
       410        420        430        440        450
QHLGTQVVKK PEYMCHTCKN CFYSLSTLNI HIRTHTGEKP FDCDLCDKKF 
       460        470        480        490        500
SALVALKKHR RYHTGEKPYS CTVCNQAFAV KEVLNRHMKR HTGERPHKCD 
       510        520        530        540        550
ECGKSFIQAT QLRTHSKTHI RPFPCEQCDE KFKTEKQLER HVKTHSRTKR 
       560        570        580        590        600
PVFSCAECKR NFRTPALLKE HMDEGKHSPK QQRSSMRSAV KIMERTDCAI 
       610        620        630        640        650
CDKNFDSSDT LRRHIRTVHE CDPDDIFGVE PHPSKRAKKD IESEEVVPVA 
       660        670        680        690        700
LNTSAGSLIS SQTDGNGVVV REFLVDEGDG AAQTITLENE TYTILPLDGA 
       710        720        730        740        750
IEGEQLTDEA GVKPEAKKEE AQVSPVVKKE QRKSLAASLA AAIADNLEES 
       760        770        780        790        800
CSEDDFSGEI LTEEDIKLKE NVGKLIDMLV DPPILKKYGW PNAPEETVLC 
       810        820        830        840        850
KVIENCGHDL TKGGENYAEL DYGSRMREYC KLLFTVVIHN DSIKSLLNNF 
       860        870        880        890        900
PIDDVIEYVL GDEDQDEGGL DKDNESHSGD EEAVSVTGET KTNEIREKPE 
       910        920        930        940 
KKEVSAKSEK KEIVGKAVDK DNSEEVVREN KKKPVGEQEK A
Length:941
Mass (Da):105,780
Last modified:August 15, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i60C6243AD088F961
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4K6W1A0A0B4K6W1_DROME
Suppressor of hairy wing, isoform C
su(Hw) Dmel\CG8573, SU(HW), Su(HW), Su(Hw), Su(hw)
941Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti31R → K in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti61E → G in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti64G → D in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti68G → E in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti249H → R in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti347P → S in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti508Q → R in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti667G → D in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti874N → NEDN in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti892T → K in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti896R → K in CAA68371 (PubMed:2462523).Curated1
Sequence conflicti923S → T in CAA68371 (PubMed:2462523).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Y00228 Genomic DNA Translation: CAA68371.1
AE014297 Genomic DNA Translation: AAF55044.1
BT003273 mRNA Translation: AAO25030.1

Protein sequence database of the Protein Information Resource

More...PIRi		S01909

NCBI Reference Sequences

More...RefSeqi		NP_001247098.1, NM_001260169.2
NP_524349.1, NM_079625.3
NP_731897.1, NM_169574.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0082945; FBpp0082404; FBgn0003567
FBtr0082946; FBpp0082405; FBgn0003567
FBtr0310002; FBpp0301708; FBgn0003567

Database of genes from NCBI RefSeq genomes

More...GeneIDi		41740

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		dme:Dmel_CG8573

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y00228 Genomic DNA Translation: CAA68371.1
AE014297 Genomic DNA Translation: AAF55044.1
BT003273 mRNA Translation: AAO25030.1
PIRiS01909
RefSeqiNP_001247098.1, NM_001260169.2
NP_524349.1, NM_079625.3
NP_731897.1, NM_169574.2

3D structure databases

SMRiP08970
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi66816, 53 interactors
DIPiDIP-17895N
IntActiP08970, 21 interactors
MINTiP08970
STRINGi7227.FBpp0082404

PTM databases

iPTMnetiP08970

Proteomic databases

PaxDbiP08970
PRIDEiP08970

Genome annotation databases

EnsemblMetazoaiFBtr0082945; FBpp0082404; FBgn0003567
FBtr0082946; FBpp0082405; FBgn0003567
FBtr0310002; FBpp0301708; FBgn0003567
GeneIDi41740
KEGGidme:Dmel_CG8573

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		41740
FlyBaseiFBgn0003567, su(Hw)

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000166978
HOGENOMiCLU_013489_0_0_1
InParanoidiP08970
OMAiKMDHYVL
OrthoDBi1318335at2759
PhylomeDBiP08970

Enzyme and pathway databases

SignaLinkiP08970

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		41740, 0 hits in 1 CRISPR screen

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		su(Hw), fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		41740

Protein Ontology

More...PROi		PR:P08970

Gene expression databases

BgeeiFBgn0003567, Expressed in embryo and 75 other tissues
ExpressionAtlasiP08970, baseline and differential
GenevisibleiP08970, DM

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 12 hits
SUPFAMiSSF57667, SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSUHW_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P08970
Secondary accession number(s): Q0KI74, Q9VFK9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: August 15, 2003
Last modified: February 10, 2021
This is version 196 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
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