Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Meiosis protein mei2

Gene

mei2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Crucial for commitment to meiosis but it is not sufficient itself for the commitment. May be a splicing regulator.

Miscellaneous

The expression of mei2 protein is negatively controlled by cAMP.

GO - Molecular functioni

  • RNA binding Source: PomBase

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processMeiosis, Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Meiosis protein mei2
Gene namesi
Name:mei2
ORF Names:SPAC27D7.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC27D7.03c
PomBaseiSPAC27D7.03c mei2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000816261 – 750Meiosis protein mei2Add BLAST750

Post-translational modificationi

Inactivated by phosphorylation by ran1/pat1.

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP08965
PaxDbiP08965
PRIDEiP08965

PTM databases

iPTMnetiP08965

Expressioni

Inductioni

By nitrogen starvation.

Interactioni

Subunit structurei

Binds rad24 when phosphorylated.

Protein-protein interaction databases

BioGridi278557, 37 interactors
STRINGi4896.SPAC27D7.03c.1

Structurei

3D structure databases

ProteinModelPortaliP08965
SMRiP08965
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini195 – 270RRM 1PROSITE-ProRule annotationAdd BLAST76
Domaini293 – 361RRM 2PROSITE-ProRule annotationAdd BLAST69

Keywords - Domaini

Repeat

Phylogenomic databases

InParanoidiP08965
OMAiMDENPAY
OrthoDBiEOG092C529D
PhylomeDBiP08965

Family and domain databases

CDDicd12528 RRM2_MEI2_fungi, 1 hit
cd12532 RRM3_MEI2_fungi, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR034863 Fungal_Mei2-like_RRM2
IPR034862 Fungal_Mei2-like_RRM3
IPR007201 Mei2-like_Rrm_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PF04059 RRM_2, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

Sequencei

Sequence statusi: Complete.

P08965-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIMETESPLS ITSPSPSDST FQVDMEKTMH ALPSSLLDSP LLSTNEHYPP
60 70 80 90 100
KSTLLLSGPS PIRNIQLSAT KSSESNSIDY LTDTQNIFPN FVNNENNYQF
110 120 130 140 150
STAPLNPIDA CRVGERKVFT TGNVLLSADR QPLSTWQQNI SVLSESPPQN
160 170 180 190 200
GIQSYISSSE QAAQALTRKP SVTGFRSSSL NSNSDDIDIF SHASRYLFVT
210 220 230 240 250
NLPRIVPYAT LLELFSKLGD VKGIDTSSLS TDGICIVAFF DIRQAIQAAK
260 270 280 290 300
SLRSQRFFND RLLYFQFCQR SSIQKMINQG ATIQFLDDNE GQLLLNMQGG
310 320 330 340 350
SVLSILQLQS ILQTFGPLLI MKPLRSQNVS QIICEFYDTR DASFALDELD
360 370 380 390 400
GRIIHNCCLQ VAYYDAMADS VSTSSASSLS VPRGFSGMLN NNSEWNNSMT
410 420 430 440 450
MSSNQETPTA ASCAVSRIGS SYGMSNNFGS VPLGRTESSP AWGTSGYYDV
460 470 480 490 500
SSTSPVAPSD RNPSRQYNSI RYGLDVNPIA PPNSSRLKQR NSDLLNGINP
510 520 530 540 550
QWSPFSSNTG KVFDSPTGSL GMRRSLTVGA NASCSNPTNL SFASLTLHDS
560 570 580 590 600
KADSTLSASS LNPDLNLQRY TPTVEKHASD RNSVDYAQIA SGIDTRTTVM
610 620 630 640 650
IKNIPNKFTQ QMLRDYIDVT NKGTYDFLYL RIDFVNKCNV GYAFINFIEP
660 670 680 690 700
QSIITFGKAR VGTQWNVFHS EKICDISYAN IQGKDRLIEK FRNSCVMDEN
710 720 730 740 750
PAYRPKIFVS HGPNRGMEEP FPAPNNARRK LRSIASAQQI GLFPPTASKC
Length:750
Mass (Da):82,677
Last modified:November 1, 1988 - v1
Checksum:iA13D9E75F48D09DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07180 Genomic DNA Translation: CAA30165.1
CU329670 Genomic DNA Translation: CAA15822.1
PIRiS00391 COZPME
RefSeqiNP_594609.1, NM_001020037.2

Genome annotation databases

EnsemblFungiiSPAC27D7.03c.1; SPAC27D7.03c.1:pep; SPAC27D7.03c
GeneIDi2542080
KEGGispo:SPAC27D7.03c

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07180 Genomic DNA Translation: CAA30165.1
CU329670 Genomic DNA Translation: CAA15822.1
PIRiS00391 COZPME
RefSeqiNP_594609.1, NM_001020037.2

3D structure databases

ProteinModelPortaliP08965
SMRiP08965
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278557, 37 interactors
STRINGi4896.SPAC27D7.03c.1

PTM databases

iPTMnetiP08965

Proteomic databases

MaxQBiP08965
PaxDbiP08965
PRIDEiP08965

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC27D7.03c.1; SPAC27D7.03c.1:pep; SPAC27D7.03c
GeneIDi2542080
KEGGispo:SPAC27D7.03c

Organism-specific databases

EuPathDBiFungiDB:SPAC27D7.03c
PomBaseiSPAC27D7.03c mei2

Phylogenomic databases

InParanoidiP08965
OMAiMDENPAY
OrthoDBiEOG092C529D
PhylomeDBiP08965

Miscellaneous databases

PROiPR:P08965

Family and domain databases

CDDicd12528 RRM2_MEI2_fungi, 1 hit
cd12532 RRM3_MEI2_fungi, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR034863 Fungal_Mei2-like_RRM2
IPR034862 Fungal_Mei2-like_RRM3
IPR007201 Mei2-like_Rrm_C
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PF04059 RRM_2, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 2 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMEI2_SCHPO
AccessioniPrimary (citable) accession number: P08965
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: November 1, 1988
Last modified: November 7, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again