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Entry version 177 (08 May 2019)
Sequence version 3 (20 Mar 2007)
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Protein

Myosin-2 heavy chain

Gene

mhcA

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.

Miscellaneous

Dictyostelium myosin-2 has no K2EDTA ATPase activity, perhaps correlated with the absence of a Cys at the SH-1 position (688).

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi179 – 186ATP8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding, Calmodulin-binding, Motor protein, Myosin
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.6.4.1 1939

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DDI-5627123 RHO GTPases activate PAKs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Myosin-2 heavy chain
Alternative name(s):
Myosin II heavy chain
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mhcA
ORF Names:DDB_G0286355
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDictyostelium discoideum (Slime mold)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri44689 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002195 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 4, Unassembled WGS sequence

Organism-specific databases

Dictyostelium discoideum online informatics resource

More...
dictyBasei
DDB_G0286355 mhcA

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

  • cell cortex
  • Note: Highest concentration in the posterior cell cortex.

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001233731 – 2116Myosin-2 heavy chainAdd BLAST2116

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei130N6,N6-dimethyllysineSequence analysis1
Modified residuei1823Phosphothreonine; by MHCK2 Publications1
Modified residuei1833Phosphothreonine; by MHCK2 Publications1
Modified residuei2029Phosphothreonine; by MHCK2 Publications1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylation inhibits thick filament formation and reduces the actin-activated ATPase activity.2 Publications

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P08799

PRoteomics IDEntifications database

More...
PRIDEi
P08799

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P08799

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Myosin-2 heavy chain is two-headed. It self-assembles into filaments. Hexamer of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Associates with elmoA.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

Database of interacting proteins

More...
DIPi
DIP-46078N

Protein interaction database and analysis system

More...
IntActi
P08799, 2 interactors

STRING: functional protein association networks

More...
STRINGi
44689.DDB0191444

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

12116
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P08799

Database of comparative protein structure models

More...
ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P08799

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini30 – 82Myosin N-terminal SH3-likePROSITE-ProRule annotationAdd BLAST53
Domaini86 – 759Myosin motorPROSITE-ProRule annotationAdd BLAST674
Domaini762 – 791IQPROSITE-ProRule annotationAdd BLAST30

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni638 – 660Actin-bindingAdd BLAST23
Regioni738 – 752Actin-bindingAdd BLAST15

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili817 – 2116Sequence analysisAdd BLAST1300

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Limited proteolysis of myosin heavy chain produces 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). HMM can be further cleaved into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).Curated
The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0161 Eukaryota
COG5022 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P08799

KEGG Orthology (KO)

More...
KOi
K10352

Identification of Orthologs from Complete Genome Data

More...
OMAi
NAHNEAQ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P08799

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.360, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00063 Myosin_head, 1 hit
PF02736 Myosin_N, 1 hit
PF01576 Myosin_tail_1, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00193 MYOSINHEAVY

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00242 MYSc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50084 SSF50084, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096 IQ, 1 hit
PS51456 MYOSIN_MOTOR, 1 hit
PS51844 SH3_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P08799-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNPIHDRTSD YHKYLKVKQG DSDLFKLTVS DKRYIWYNPD PKERDSYECG
60 70 80 90 100
EIVSETSDSF TFKTVDGQDR QVKKDDANQR NPIKFDGVED MSELSYLNEP
110 120 130 140 150
AVFHNLRVRY NQDLIYTYSG LFLVAVNPFK RIPIYTQEMV DIFKGRRRNE
160 170 180 190 200
VAPHIFAISD VAYRSMLDDR QNQSLLITGE SGAGKTENTK KVIQYLASVA
210 220 230 240 250
GRNQANGSGV LEQQILQANP ILEAFGNAKT TRNNNSSRFG KFIEIQFNSA
260 270 280 290 300
GFISGASIQS YLLEKSRVVF QSETERNYHI FYQLLAGATA EEKKALHLAG
310 320 330 340 350
PESFNYLNQS GCVDIKGVSD SEEFKITRQA MDIVGFSQEE QMSIFKIIAG
360 370 380 390 400
ILHLGNIKFE KGAGEGAVLK DKTALNAAST VFGVNPSVLE KALMEPRILA
410 420 430 440 450
GRDLVAQHLN VEKSSSSRDA LVKALYGRLF LWLVKKINNV LCQERKAYFI
460 470 480 490 500
GVLDISGFEI FKVNSFEQLC INYTNEKLQQ FFNHHMFKLE QEEYLKEKIN
510 520 530 540 550
WTFIDFGLDS QATIDLIDGR QPPGILALLD EQSVFPNATD NTLITKLHSH
560 570 580 590 600
FSKKNAKYEE PRFSKTEFGV THYAGQVMYE IQDWLEKNKD PLQQDLELCF
610 620 630 640 650
KDSSDNVVTK LFNDPNIASR AKKGANFITV AAQYKEQLAS LMATLETTNP
660 670 680 690 700
HFVRCIIPNN KQLPAKLEDK VVLDQLRCNG VLEGIRITRK GFPNRIIYAD
710 720 730 740 750
FVKRYYLLAP NVPRDAEDSQ KATDAVLKHL NIDPEQYRFG ITKIFFRAGQ
760 770 780 790 800
LARIEEAREQ RISEIIKAIQ AATRGWIARK VYKQAREHTV AARIIQQNLR
810 820 830 840 850
AYIDFKSWPW WKLFSKARPL LKRRNFEKEI KEKEREILEL KSNLTDSTTQ
860 870 880 890 900
KDKLEKSLKD TESNVLDLQR QLKAEKETLK AMYDSKDALE AQKRELEIRV
910 920 930 940 950
EDMESELDEK KLALENLQNQ KRSVEEKVRD LEEELQEEQK LRNTLEKLKK
960 970 980 990 1000
KYEEELEEMK RVNDGQSDTI SRLEKIKDEL QKEVEELTES FSEESKDKGV
1010 1020 1030 1040 1050
LEKTRVRLQS ELDDLTVRLD SETKDKSELL RQKKKLEEEL KQVQEALAAE
1060 1070 1080 1090 1100
TAAKLAQEAA NKKLQGEYTE LNEKFNSEVT ARSNVEKSKK TLESQLVAVN
1110 1120 1130 1140 1150
NELDEEKKNR DALEKKKKAL DAMLEEMKDQ LESTGGEKKS LYDLKVKQES
1160 1170 1180 1190 1200
DMEALRNQIS ELQSTIAKLE KIKSTLEGEV ARLQGELEAE QLAKSNVEKQ
1210 1220 1230 1240 1250
KKKVELDLED KSAQLAEETA AKQALDKLKK KLEQELSEVQ TQLSEANNKN
1260 1270 1280 1290 1300
VNSDSTNKHL ETSFNNLKLE LEAEQKAKQA LEKKRLGLES ELKHVNEQLE
1310 1320 1330 1340 1350
EEKKQKESNE KRKVDLEKEV SELKDQIEEE VASKKAVTEA KNKKESELDE
1360 1370 1380 1390 1400
IKRQYADVVS SRDKSVEQLK TLQAKNEELR NTAEEAEGQL DRAERSKKKA
1410 1420 1430 1440 1450
EFDLEEAVKN LEEETAKKVK AEKAMKKAET DYRSTKSELD DAKNVSSEQY
1460 1470 1480 1490 1500
VQIKRLNEEL SELRSVLEEA DERCNSAIKA KKTAESALES LKDEIDAANN
1510 1520 1530 1540 1550
AKAKAERKSK ELEVRVAELE ESLEDKSGTV NVEFIRKKDA EIDDLRARLD
1560 1570 1580 1590 1600
RETESRIKSD EDKKNTRKQF ADLEAKVEEA QREVVTIDRL KKKLESDIID
1610 1620 1630 1640 1650
LSTQLDTETK SRIKIEKSKK KLEQTLAERR AAEEGSSKAA DEEIRKQVWQ
1660 1670 1680 1690 1700
EVDELRAQLD SERAALNASE KKIKSLVAEV DEVKEQLEDE ILAKDKLVKA
1710 1720 1730 1740 1750
KRALEVELEE VRDQLEEEED SRSELEDSKR RLTTEVEDIK KKYDAEVEQN
1760 1770 1780 1790 1800
TKLDEAKKKL TDDVDTLKKQ LEDEKKKLNE SERAKKRLES ENEDFLAKLD
1810 1820 1830 1840 1850
AEVKNRSRAE KDRKKYEKDL KDTKYKLNDE AATKTQTEIG AAKLEDQIDE
1860 1870 1880 1890 1900
LRSKLEQEQA KATQADKSKK TLEGEIDNLR AQIEDEGKIK MRLEKEKRAL
1910 1920 1930 1940 1950
EGELEELRET VEEAEDSKSE AEQSKRLVEL ELEDARRNLQ KEIDAKEIAE
1960 1970 1980 1990 2000
DAKSNLQREI VEAKGRLEEE SIARTNSDRS RKRLEAEIDA LTAQVDAEQK
2010 2020 2030 2040 2050
AKNQQIKENK KIETELKEYR KKFGESEKTK TKEFLVVEKL ETDYKRAKKE
2060 2070 2080 2090 2100
AADEQQQRLT VENDLRKHLS EISLLKDAID KLQRDHDKTK RELETETASK
2110
IEMQRKMADF FGGFKA
Length:2,116
Mass (Da):243,786
Last modified:March 20, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i97DE4FB422AD3D56
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti249S → N in AAA33227 (PubMed:3540939).Curated1
Sequence conflicti312C → Y in AAA33227 (PubMed:3540939).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M14628 Genomic DNA Translation: AAA33227.1
AAFI02000085 Genomic DNA Translation: EAL64202.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A26655

NCBI Reference Sequences

More...
RefSeqi
XP_637740.1, XM_632648.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EAL64202; EAL64202; DDB_G0286355

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
8625606

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ddi:DDB_G0286355

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14628 Genomic DNA Translation: AAA33227.1
AAFI02000085 Genomic DNA Translation: EAL64202.1
PIRiA26655
RefSeqiXP_637740.1, XM_632648.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1D0XX-ray2.00A1-759[»]
1D0YX-ray2.00A1-759[»]
1D0ZX-ray2.00A1-759[»]
1D1AX-ray2.00A1-759[»]
1D1BX-ray2.00A1-759[»]
1D1CX-ray2.30A1-759[»]
1FMVX-ray2.10A1-759[»]
1FMWX-ray2.15A1-759[»]
1G8XX-ray2.80A/B1-761[»]
1JWYX-ray2.30A3-765[»]
1JX2X-ray2.30A3-765[»]
1LVKX-ray1.90A1-759[»]
1MMAX-ray2.10A1-759[»]
1MMDX-ray2.00A1-759[»]
1MMGX-ray2.10A1-759[»]
1MMNX-ray2.10A1-759[»]
1MNDX-ray2.60A1-759[»]
1MNEX-ray2.70A1-759[»]
1Q5Gmodel-A2-765[»]
1VOMX-ray1.90A1-759[»]
1W9IX-ray1.75A1-759[»]
1W9JX-ray2.00A1-758[»]
1W9KX-ray2.05A1-759[»]
1W9LX-ray1.95A1-759[»]
1YV3X-ray2.00A1-762[»]
2AKAX-ray1.90A2-765[»]
2JHRX-ray2.80A2-761[»]
2JJ9X-ray2.30A2-761[»]
2X9HX-ray2.70A3-696[»]
2XELX-ray2.50A2-761[»]
2XO8X-ray2.40A3-761[»]
2Y0RX-ray2.85X2-759[»]
2Y8IX-ray3.13X2-759[»]
2Y9EX-ray3.40X2-759[»]
3BZ7X-ray2.00A2-759[»]
3BZ8X-ray2.20A2-759[»]
3BZ9X-ray2.10A2-759[»]
3MJXX-ray2.20A2-761[»]
3MKDX-ray2.40A2-693[»]
3MNQX-ray2.20A3-761[»]
3MYHX-ray2.01X2-759[»]
3MYKX-ray1.84X2-759[»]
3MYLX-ray2.00X2-759[»]
4AE3X-ray2.50A2-761[»]
4PJKX-ray2.15A1-761[»]
SMRiP08799
ModBaseiSearch...

Protein-protein interaction databases

DIPiDIP-46078N
IntActiP08799, 2 interactors
STRINGi44689.DDB0191444

PTM databases

iPTMnetiP08799

Proteomic databases

PaxDbiP08799
PRIDEiP08799

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAL64202; EAL64202; DDB_G0286355
GeneIDi8625606
KEGGiddi:DDB_G0286355

Organism-specific databases

dictyBaseiDDB_G0286355 mhcA

Phylogenomic databases

eggNOGiKOG0161 Eukaryota
COG5022 LUCA
InParanoidiP08799
KOiK10352
OMAiNAHNEAQ
PhylomeDBiP08799

Enzyme and pathway databases

BRENDAi3.6.4.1 1939
ReactomeiR-DDI-5627123 RHO GTPases activate PAKs

Miscellaneous databases

EvolutionaryTraceiP08799

Protein Ontology

More...
PROi
PR:P08799

Family and domain databases

Gene3Di2.30.30.360, 1 hit
3.40.850.10, 1 hit
4.10.270.10, 1 hit
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PF02736 Myosin_N, 1 hit
PF01576 Myosin_tail_1, 2 hits
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SUPFAMiSSF50084 SSF50084, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS51456 MYOSIN_MOTOR, 1 hit
PS51844 SH3_LIKE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMYS2_DICDI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P08799
Secondary accession number(s): Q54LU0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1988
Last sequence update: March 20, 2007
Last modified: May 8, 2019
This is version 177 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
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