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Entry version 212 (29 Sep 2021)
Sequence version 2 (23 Jan 2007)
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Protein

40S ribosomal protein S17

Gene

RPS17

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

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PathwayCommonsi
P08708

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902, Peptide chain elongation
R-HSA-1799339, SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823, Viral mRNA Translation
R-HSA-2408557, Selenocysteine synthesis
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649, Translation initiation complex formation
R-HSA-72689, Formation of a pool of free 40S subunits
R-HSA-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702, Ribosomal scanning and start codon recognition
R-HSA-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764, Eukaryotic Translation Termination
R-HSA-9010553, Regulation of expression of SLITs and ROBOs
R-HSA-9633012, Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

SIGNOR Signaling Network Open Resource

More...
SIGNORi
P08708

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
40S ribosomal protein S17Curated
Alternative name(s):
Small ribosomal subunit protein eS171 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RPS17Imported
Synonyms:RPS17LImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:10397, RPS17

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
180472, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P08708

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000182774

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Diamond-Blackfan anemia 4 (DBA4)2 Publications
The disease is caused by variants affecting the gene represented in this entry.
Disease descriptionA form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of developing leukemia. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Related information in OMIM

Keywords - Diseasei

Diamond-Blackfan anemia

Organism-specific databases

DisGeNET

More...
DisGeNETi
6218

GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

More...
GeneReviewsi
RPS17

MalaCards human disease database

More...
MalaCardsi
RPS17
MIMi612527, phenotype

Open Targets

More...
OpenTargetsi
ENSG00000182774

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
124, Blackfan-Diamond anemia

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA34797

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P08708, Tbio

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB11638, Artenimol

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RPS17

Domain mapping of disease mutations (DMDM)

More...
DMDMi
338819320

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001415252 – 13540S ribosomal protein S17Add BLAST134

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei19N6-succinyllysineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki103Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki103Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei113PhosphoserineCombined sources1
Modified residuei130PhosphothreonineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P08708

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P08708

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P08708

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P08708

PeptideAtlas

More...
PeptideAtlasi
P08708

PRoteomics IDEntifications database

More...
PRIDEi
P08708

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
52159
52521

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P08708

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
P08708, 1 site, 1 O-linked glycan (1 site)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P08708

MetOSite database of methionine sulfoxide sites

More...
MetOSitei
P08708

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P08708

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P08708

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000182774, Expressed in material anatomical entity and 251 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P08708, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P08708, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000182774, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
112132, 188 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-5223, 40S cytosolic small ribosomal subunit

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
P08708

Protein interaction database and analysis system

More...
IntActi
P08708, 57 interactors

Molecular INTeraction database

More...
MINTi
P08708

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000346046

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P08708, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1135
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P08708

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0187, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006548

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_112958_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P08708

Identification of Orthologs from Complete Genome Data

More...
OMAi
EKYYTRM

Database of Orthologous Groups

More...
OrthoDBi
1459807at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P08708

TreeFam database of animal gene trees

More...
TreeFami
TF317992

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.60.20, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00511, Ribosomal_S17e, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001210, Ribosomal_S17e
IPR018273, Ribosomal_S17e_CS
IPR036401, RPS17e-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10732, PTHR10732, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00833, Ribosomal_S17e, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF116820, SSF116820, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00712, RIBOSOMAL_S17E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P08708-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI
60 70 80 90 100
AGYVTHLMKR IQRGPVRGIS IKLQEEERER RDNYVPEVSA LDQEIIEVDP
110 120 130
DTKEMLKLLD FGSLSNLQVT QPTVGMNFKT PRGPV
Length:135
Mass (Da):15,550
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i299AD605C5401325
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YN88H0YN88_HUMAN
40S ribosomal protein S17
RPS17
136Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A075B716A0A075B716_HUMAN
40S ribosomal protein S17
RPS17
191Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YN73H0YN73_HUMAN
40S ribosomal protein S17
RPS17
59Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03447836E → K. Corresponds to variant dbSNP:rs1043734Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M13932 mRNA Translation: AAA60284.1
M18000 Genomic DNA Translation: AAA60285.1
AK026570 mRNA Translation: BAB15501.1
AK311951 mRNA Translation: BAG34891.1
AC245033 Genomic DNA No translation available.
CH471188 Genomic DNA Translation: EAW62454.1
BC009407 mRNA Translation: AAH09407.1
BC019899 mRNA Translation: AAH19899.1
BC022370 mRNA Translation: AAH22370.1
BC049824 mRNA Translation: AAH49824.1
BC070222 mRNA Translation: AAH70222.1
BC062715 mRNA Translation: AAH62715.1
BC071928 mRNA Translation: AAH71928.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10320.1

Protein sequence database of the Protein Information Resource

More...
PIRi
JT0405, R4HU17

NCBI Reference Sequences

More...
RefSeqi
NP_001012.1, NM_001021.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000617731; ENSP00000483755; ENSG00000278229
ENST00000647841; ENSP00000498019; ENSG00000182774

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6218

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:6218

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Diamond-Blackfan Anemia mutation database

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M13932 mRNA Translation: AAA60284.1
M18000 Genomic DNA Translation: AAA60285.1
AK026570 mRNA Translation: BAB15501.1
AK311951 mRNA Translation: BAG34891.1
AC245033 Genomic DNA No translation available.
CH471188 Genomic DNA Translation: EAW62454.1
BC009407 mRNA Translation: AAH09407.1
BC019899 mRNA Translation: AAH19899.1
BC022370 mRNA Translation: AAH22370.1
BC049824 mRNA Translation: AAH49824.1
BC070222 mRNA Translation: AAH70222.1
BC062715 mRNA Translation: AAH62715.1
BC071928 mRNA Translation: AAH71928.1
CCDSiCCDS10320.1
PIRiJT0405, R4HU17
RefSeqiNP_001012.1, NM_001021.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4UG0electron microscopy-SR1-135[»]
4V6Xelectron microscopy5.00AR1-135[»]
5A2Qelectron microscopy3.90R1-135[»]
5AJ0electron microscopy3.50BR1-135[»]
5FLXelectron microscopy3.90R1-135[»]
5LKSelectron microscopy3.60SR1-135[»]
5OA3electron microscopy4.30R1-135[»]
5T2Celectron microscopy3.60Az1-135[»]
5VYCX-ray6.00R1/R2/R3/R4/R5/R61-135[»]
6EK0electron microscopy2.90SR1-135[»]
6FECelectron microscopy6.30e1-126[»]
6G18electron microscopy3.60R1-135[»]
6G4Selectron microscopy4.00R1-135[»]
6G4Welectron microscopy4.50R1-135[»]
6G51electron microscopy4.10R1-135[»]
6G53electron microscopy4.50R1-135[»]
6G5Helectron microscopy3.60R1-135[»]
6G5Ielectron microscopy3.50R1-135[»]
6IP5electron microscopy3.902y1-135[»]
6IP6electron microscopy4.502y1-135[»]
6IP8electron microscopy3.902y1-135[»]
6OLEelectron microscopy3.10SR2-135[»]
6OLFelectron microscopy3.90SR2-135[»]
6OLGelectron microscopy3.40BR2-126[»]
6OLIelectron microscopy3.50SR2-135[»]
6OLZelectron microscopy3.90BR2-126[»]
6OM0electron microscopy3.10SR2-135[»]
6OM7electron microscopy3.70SR2-135[»]
6QZPelectron microscopy2.90SR1-135[»]
6XA1electron microscopy2.80SR2-132[»]
6Y0Gelectron microscopy3.20SR1-135[»]
6Y2Lelectron microscopy3.00SR1-135[»]
6Y57electron microscopy3.50SR1-135[»]
6YBDelectron microscopy3.30M1-135[»]
6YBSelectron microscopy3.10X1-135[»]
6YBWelectron microscopy3.10M1-135[»]
6Z6Lelectron microscopy3.00SR1-135[»]
6Z6Melectron microscopy3.10SR1-135[»]
6Z6Nelectron microscopy2.90SR1-135[»]
6ZLWelectron microscopy2.60S1-135[»]
6ZM7electron microscopy2.70SR1-135[»]
6ZMEelectron microscopy3.00SR1-135[»]
6ZMIelectron microscopy2.60SR1-135[»]
6ZMOelectron microscopy3.10SR1-135[»]
6ZMTelectron microscopy3.00S1-135[»]
6ZMWelectron microscopy3.70M1-135[»]
6ZN5electron microscopy3.20S2-133[»]
6ZOJelectron microscopy2.80R1-135[»]
6ZOKelectron microscopy2.80R1-135[»]
6ZOLelectron microscopy2.80R1-135[»]
6ZONelectron microscopy3.00w1-135[»]
6ZP4electron microscopy2.90w1-135[»]
6ZUOelectron microscopy3.10R1-135[»]
6ZV6electron microscopy2.90R1-135[»]
6ZVHelectron microscopy2.90R1-135[»]
6ZVJelectron microscopy3.80w2-131[»]
6ZXDelectron microscopy3.20R1-135[»]
6ZXEelectron microscopy3.00R1-135[»]
6ZXFelectron microscopy3.70R1-135[»]
6ZXGelectron microscopy2.60R1-135[»]
6ZXHelectron microscopy2.70R1-135[»]
7A09electron microscopy3.50w1-135[»]
7K5Ielectron microscopy2.90R1-135[»]
SMRiP08708
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi112132, 188 interactors
ComplexPortaliCPX-5223, 40S cytosolic small ribosomal subunit
CORUMiP08708
IntActiP08708, 57 interactors
MINTiP08708
STRINGi9606.ENSP00000346046

Chemistry databases

DrugBankiDB11638, Artenimol

PTM databases

GlyGeniP08708, 1 site, 1 O-linked glycan (1 site)
iPTMnetiP08708
MetOSiteiP08708
PhosphoSitePlusiP08708
SwissPalmiP08708

Genetic variation databases

BioMutaiRPS17
DMDMi338819320

Proteomic databases

EPDiP08708
jPOSTiP08708
MassIVEiP08708
PaxDbiP08708
PeptideAtlasiP08708
PRIDEiP08708
ProteomicsDBi52159
52521
TopDownProteomicsiP08708

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
56676, 145 antibodies

The DNASU plasmid repository

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DNASUi
6218

Genome annotation databases

EnsembliENST00000617731; ENSP00000483755; ENSG00000278229
ENST00000647841; ENSP00000498019; ENSG00000182774
GeneIDi6218
KEGGihsa:6218

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6218
DisGeNETi6218

GeneCards: human genes, protein and diseases

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GeneCardsi
RPS17
GeneReviewsiRPS17
HGNCiHGNC:10397, RPS17
HPAiENSG00000182774, Low tissue specificity
MalaCardsiRPS17
MIMi180472, gene
612527, phenotype
neXtProtiNX_P08708
OpenTargetsiENSG00000182774
Orphaneti124, Blackfan-Diamond anemia
PharmGKBiPA34797
VEuPathDBiHostDB:ENSG00000182774

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0187, Eukaryota
GeneTreeiENSGT00390000006548
HOGENOMiCLU_112958_1_1_1
InParanoidiP08708
OMAiEKYYTRM
OrthoDBi1459807at2759
PhylomeDBiP08708
TreeFamiTF317992

Enzyme and pathway databases

PathwayCommonsiP08708
ReactomeiR-HSA-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156902, Peptide chain elongation
R-HSA-1799339, SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823, Viral mRNA Translation
R-HSA-2408557, Selenocysteine synthesis
R-HSA-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-72649, Translation initiation complex formation
R-HSA-72689, Formation of a pool of free 40S subunits
R-HSA-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702, Ribosomal scanning and start codon recognition
R-HSA-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72764, Eukaryotic Translation Termination
R-HSA-9010553, Regulation of expression of SLITs and ROBOs
R-HSA-9633012, Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
SIGNORiP08708

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
6218, 388 hits in 579 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
RPS17, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
RPS17

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
6218
PharosiP08708, Tbio

Protein Ontology

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PROi
PR:P08708
RNActiP08708, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000182774, Expressed in material anatomical entity and 251 other tissues
ExpressionAtlasiP08708, baseline and differential
GenevisibleiP08708, HS

Family and domain databases

Gene3Di1.10.60.20, 1 hit
HAMAPiMF_00511, Ribosomal_S17e, 1 hit
InterProiView protein in InterPro
IPR001210, Ribosomal_S17e
IPR018273, Ribosomal_S17e_CS
IPR036401, RPS17e-like_sf
PANTHERiPTHR10732, PTHR10732, 1 hit
PfamiView protein in Pfam
PF00833, Ribosomal_S17e, 1 hit
SUPFAMiSSF116820, SSF116820, 1 hit
PROSITEiView protein in PROSITE
PS00712, RIBOSOMAL_S17E, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRS17_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P08708
Secondary accession number(s): B2R4U4, P0CW22
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 23, 2007
Last modified: September 29, 2021
This is version 212 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  7. SIMILARITY comments
    Index of protein domains and families
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