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Entry version 246 (18 Sep 2019)
Sequence version 4 (23 Jan 2007)
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Protein

Vimentin

Gene

VIM

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.1 Publication
Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei351Stutter1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processHost-virus interaction

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

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Reactomei
R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins
R-HSA-390522 Striated Muscle Contraction
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling

SIGNOR Signaling Network Open Resource

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SIGNORi
P08670

Protein family/group databases

MoonDB Database of extreme multifunctional and moonlighting proteins

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MoonDBi
P08670 Predicted

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vimentin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:VIM
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:12692 VIM

Online Mendelian Inheritance in Man (OMIM)

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MIMi
193060 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P08670

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Intermediate filament, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Cataract 30, multiple types (CTRCT30)3 Publications
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function.
Related information in OMIM
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_070100151E → K in CTRCT30; the mutation increases the proteasome activity in transfected cells; causes also a severe kinetic defect in vimentin assembly both in vitro and in vivo. 1 PublicationCorresponds to variant dbSNP:rs121917775EnsemblClinVar.1
Natural variantiVAR_078860208Q → R in CTRCT30; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1085307141EnsemblClinVar.1

Keywords - Diseasei

Cataract, Disease mutation

Organism-specific databases

DisGeNET

More...
DisGeNETi
7431

MalaCards human disease database

More...
MalaCardsi
VIM
MIMi116300 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000026025

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
98984 Pulverulent cataract

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37311

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL3712854

Drug and drug target database

More...
DrugBanki
DB11638 Artenimol
DB12695 Phenethyl Isothiocyanate

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
VIM

Domain mapping of disease mutations (DMDM)

More...
DMDMi
55977767

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000637542 – 466VimentinAdd BLAST465

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserine1 Publication1
Modified residuei5PhosphoserineCombined sources1 Publication1
Modified residuei7Phosphoserine; by PKA and PKC; alternate1 Publication1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi7O-linked (GlcNAc) serine; alternate1 Publication1
Modified residuei8Phosphoserine1 Publication1
Modified residuei9Phosphoserine; by PKC1 Publication1
Modified residuei10Phosphoserine; by PKC1 Publication1
Modified residuei20PhosphothreonineCombined sources1
Modified residuei25PhosphoserineCombined sources1
Modified residuei26PhosphoserineCombined sources1
Glycosylationi33O-linked (GlcNAc) threonine1 Publication1
Modified residuei34Phosphoserine; by PKC; alternateCombined sources1
Glycosylationi34O-linked (GlcNAc) serine; alternate1 Publication1
Modified residuei39Phosphoserine; by CaMK2, PKA, PKC and ROCK2Combined sources1 Publication1
Modified residuei42Phosphoserine; by PKCCombined sources1 Publication1
Modified residuei47PhosphoserineCombined sources1
Modified residuei49PhosphoserineCombined sources1
Modified residuei51PhosphoserineCombined sources1
Modified residuei53PhosphotyrosineBy similarity1
Modified residuei55PhosphoserineBy similarity1
Modified residuei56Phosphoserine; by CDK5 and CDK1Combined sources2 Publications1
Modified residuei61PhosphotyrosineCombined sources1
Modified residuei66PhosphoserineCombined sources1
Modified residuei72Phosphoserine; by AURKB and ROCK2Combined sources2 Publications1
Modified residuei73PhosphoserineCombined sources1 Publication1
Modified residuei83PhosphoserineCombined sources1
Modified residuei87PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki104Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei117PhosphotyrosineCombined sources1
Modified residuei120N6-acetyllysine; alternateCombined sources1
Modified residuei120N6-succinyllysine; alternateBy similarity1
Cross-linki120Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei129N6-acetyllysine; alternateBy similarity1
Modified residuei129N6-succinyllysine; alternateBy similarity1
Cross-linki129Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei139N6-acetyllysine; alternateCombined sources1
Cross-linki139Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei144PhosphoserineCombined sources1
Modified residuei168N6-acetyllysineBy similarity1
Modified residuei188N6-acetyllysine; alternateBy similarity1
Modified residuei188N6-succinyllysine; alternateBy similarity1
Modified residuei214PhosphoserineCombined sources1
Modified residuei223N6-acetyllysine; alternateBy similarity1
Cross-linki223Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei226PhosphoserineCombined sources1
Modified residuei235N6-acetyllysineBy similarity1
Cross-linki262Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei294N6-acetyllysine; alternateBy similarity1
Modified residuei294N6-succinyllysine; alternateBy similarity1
Cross-linki294Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei299PhosphoserineCombined sources1
Cross-linki313Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei325PhosphoserineBy similarity1
Modified residuei373N6-acetyllysine; alternateCombined sources1
Cross-linki373Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei409PhosphoserineCombined sources1
Modified residuei412PhosphoserineCombined sources1
Modified residuei419PhosphoserineCombined sources1
Modified residuei420PhosphoserineCombined sources1 Publication1
Modified residuei426PhosphothreonineCombined sources1
Modified residuei430PhosphoserineCombined sources1 Publication1
Modified residuei436PhosphothreonineCombined sources1
Modified residuei438PhosphoserineCombined sources1
Cross-linki439Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei445N6-acetyllysine; alternateCombined sources1
Modified residuei445N6-succinyllysine; alternateBy similarity1
Cross-linki445Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateCombined sources
Cross-linki445Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateCombined sources
Modified residuei446PhosphothreonineCombined sources1
Modified residuei458Phosphothreonine1 Publication1
Modified residuei459PhosphoserineCombined sources1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Filament disassembly during mitosis is promoted by phosphorylation at Ser-55 as well as by nestin (By similarity). One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized. Phosphorylation by PKN1 inhibits the formation of filaments. Phosphorylated at Ser-56 by CDK5 during neutrophil secretion in the cytoplasm (PubMed:21465480). Phosphorylated by STK33 (PubMed:18811945). Phosphorylated on tyrosine residues by SRMS (PubMed:29496907).By similarity4 Publications
O-glycosylated during cytokinesis at sites identical or close to phosphorylation sites, this interferes with the phosphorylation status.1 Publication
S-nitrosylation is induced by interferon-gamma and oxidatively-modified low-densitity lipoprotein (LDL(ox)) possibly implicating the iNOS-S100A8/9 transnitrosylase complex.1 Publication

Keywords - PTMi

Acetylation, Glycoprotein, Isopeptide bond, Phosphoprotein, S-nitrosylation, Ubl conjugation

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
CPTAC-1017
CPTAC-1018
CPTAC-1036
CPTAC-1303
CPTAC-297
CPTAC-298

Encyclopedia of Proteome Dynamics

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EPDi
P08670

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P08670

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
P08670

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
P08670

PeptideAtlas

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PeptideAtlasi
P08670

PRoteomics IDEntifications database

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PRIDEi
P08670

ProteomicsDB human proteome resource

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ProteomicsDBi
52153

Consortium for Top Down Proteomics

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TopDownProteomicsi
P08670

2D gel databases

DOSAC-COBS 2D-PAGE database

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DOSAC-COBS-2DPAGEi
P08670

USC-OGP 2-DE database

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OGPi
P08670

REPRODUCTION-2DPAGE

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REPRODUCTION-2DPAGEi
IPI00418471
P08670

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

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SWISS-2DPAGEi
P08670

University College Dublin 2-DE Proteome Database

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UCD-2DPAGEi
P08670

PTM databases

CarbonylDB database of protein carbonylation sites

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CarbonylDBi
P08670

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
P08670

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P08670

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P08670

Miscellaneous databases

CutDB - Proteolytic event database

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PMAP-CutDBi
P08670

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.2 Publications

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by muramyl-dipeptide and lipopolysaccharide.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000026025 Expressed in 241 organ(s), highest expression level in dorsal root ganglion

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
P08670 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
P08670 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB000080
CAB058687
HPA001762

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homopolymer assembled from elementary dimers.

Interacts with LGSN and SYNM.

Interacts (via rod region) with PLEC (via CH 1 domain) (By similarity).

Interacts with SLC6A4 (PubMed:19270731).

Interacts with STK33 (PubMed:18811945).

Interacts with LARP6 (PubMed:21746880).

Interacts with RAB8B (By similarity).

Interacts with TOR1A; the interaction associates TOR1A with the cytoskeleton (PubMed:16361107, PubMed:18827015).

Interacts with TOR1AIP1 (PubMed:16361107).

Interacts with BCAS3 (PubMed:17505058).

Interacts with DIAPH1 (PubMed:23325789). Identified in complexes that contain VIM, EZR, AHNAK, BFSP1, BFSP2, ANK2, PLEC, PRX and spectrin (By similarity).

Interacts with EPPK1; interaction is dependent of higher-order structure of intermediate filament (PubMed:16923132).

Interacts with the non-receptor tyrosine kinase SRMS; the interaction leads to phosphorylation of VIM (PubMed:29496907).

Interacts with NOD2 (PubMed:27812135).

Interacts (via head region) with CORO1C (By similarity).

Interacts with HDGF (isoform 2) (PubMed:26845719).

By similarity13 Publications

(Microbial infection)

Interacts with HCV core protein.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113272, 315 interactors

CORUM comprehensive resource of mammalian protein complexes

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CORUMi
P08670

Database of interacting proteins

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DIPi
DIP-32507N

Protein interaction database and analysis system

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IntActi
P08670, 270 interactors

Molecular INTeraction database

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MINTi
P08670

STRING: functional protein association networks

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STRINGi
9606.ENSP00000446007

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1466
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P08670

Database of comparative protein structure models

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ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P08670

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini103 – 411IF rodPROSITE-ProRule annotationAdd BLAST309

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2 – 95HeadAdd BLAST94
Regioni96 – 131Coil 1AAdd BLAST36
Regioni132 – 153Linker 1Add BLAST22
Regioni154 – 245Coil 1BAdd BLAST92
Regioni246 – 268Linker 12Add BLAST23
Regioni269 – 407Coil 2Add BLAST139
Regioni408 – 466TailAdd BLAST59

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili96 – 1311 PublicationAdd BLAST36
Coiled coili154 – 2451 PublicationAdd BLAST92
Coiled coili303 – 4071 PublicationAdd BLAST105

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi326 – 329[IL]-x-C-x-x-[DE] motif1 Publication4

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The central alpha-helical coiled-coil IF rod domain mediates elementary homodimerization.
The [IL]-x-C-x-x-[DE] motif is a proposed target motif for cysteine S-nitrosylation mediated by the iNOS-S100A8/A9 transnitrosylase complex.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IFZ1 Eukaryota
ENOG410XRBS LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156146

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P08670

KEGG Orthology (KO)

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KOi
K07606

Identification of Orthologs from Complete Genome Data

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OMAi
QVINEST

Database of Orthologous Groups

More...
OrthoDBi
655109at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P08670

TreeFam database of animal gene trees

More...
TreeFami
TF330122

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.5.1160, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR042180 IF_rod_dom_coil1B
IPR006821 Intermed_filament_DNA-bd
IPR027699 Vimentin

The PANTHER Classification System

More...
PANTHERi
PTHR45652:SF5 PTHR45652:SF5, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00038 Filament, 1 hit
PF04732 Filament_head, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01391 Filament, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

P08670-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTRSVSSSS YRRMFGGPGT ASRPSSSRSY VTTSTRTYSL GSALRPSTSR
60 70 80 90 100
SLYASSPGGV YATRSSAVRL RSSVPGVRLL QDSVDFSLAD AINTEFKNTR
110 120 130 140 150
TNEKVELQEL NDRFANYIDK VRFLEQQNKI LLAELEQLKG QGKSRLGDLY
160 170 180 190 200
EEEMRELRRQ VDQLTNDKAR VEVERDNLAE DIMRLREKLQ EEMLQREEAE
210 220 230 240 250
NTLQSFRQDV DNASLARLDL ERKVESLQEE IAFLKKLHEE EIQELQAQIQ
260 270 280 290 300
EQHVQIDVDV SKPDLTAALR DVRQQYESVA AKNLQEAEEW YKSKFADLSE
310 320 330 340 350
AANRNNDALR QAKQESTEYR RQVQSLTCEV DALKGTNESL ERQMREMEEN
360 370 380 390 400
FAVEAANYQD TIGRLQDEIQ NMKEEMARHL REYQDLLNVK MALDIEIATY
410 420 430 440 450
RKLLEGEESR ISLPLPNFSS LNLRETNLDS LPLVDTHSKR TLLIKTVETR
460
DGQVINETSQ HHDDLE
Length:466
Mass (Da):53,652
Last modified:January 23, 2007 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBAB54026665B015A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B0YJC4B0YJC4_HUMAN
Vimentin
VIM
431Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GTT5A0A1B0GTT5_HUMAN
Vimentin
VIM
149Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B0YJC5B0YJC5_HUMAN
Vimentin
VIM
228Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1B0GVG8A0A1B0GVG8_HUMAN
Vimentin
VIM
109Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB71275 differs from that shown. Product of a cloning artifact.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti42S → D in AAA61279 (PubMed:3467175).Curated1
Sequence conflicti113R → P in CAA34499 (PubMed:2472876).Curated1
Sequence conflicti197E → G in CAG28618 (Ref. 6) Curated1
Sequence conflicti201N → S in AAA61281 (PubMed:3371665).Curated1
Sequence conflicti265L → S in AAA61281 (PubMed:3371665).Curated1
Sequence conflicti278S → I in AAA61281 (PubMed:3371665).Curated1
Sequence conflicti339S → C in AAA61281 (PubMed:3371665).Curated1
Sequence conflicti350N → K in AAA61281 (PubMed:3371665).Curated1
Sequence conflicti442L → F in AAA61279 (PubMed:3467175).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_070100151E → K in CTRCT30; the mutation increases the proteasome activity in transfected cells; causes also a severe kinetic defect in vimentin assembly both in vitro and in vivo. 1 PublicationCorresponds to variant dbSNP:rs121917775EnsemblClinVar.1
Natural variantiVAR_078860208Q → R in CTRCT30; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1085307141EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M14144 Genomic DNA Translation: AAA61279.1
X56134 mRNA Translation: CAA39600.1
AF328728 mRNA Translation: AAN09720.1
Z19554 mRNA Translation: CAA79613.2
AK056766 mRNA Translation: BAB71275.1 Sequence problems.
AK097336 mRNA Translation: BAC05002.1
AK290643 mRNA Translation: BAF83332.1
CR407690 mRNA Translation: CAG28618.1
AK222507 mRNA Translation: BAD96227.1
AK222602 mRNA Translation: BAD96322.1
EF445046 Genomic DNA Translation: ACA06101.1
EF445046 Genomic DNA Translation: ACA06102.1
AL133415 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86215.1
CH471072 Genomic DNA Translation: EAW86216.1
BC000163 mRNA Translation: AAH00163.2
BC030573 mRNA Translation: AAH30573.1
BC066956 mRNA Translation: AAH66956.1
X16478 mRNA Translation: CAA34499.1
M18895
, M18888, M18889, M18890, M18891, M18892, M18893, M18894 Genomic DNA Translation: AAA61281.2
M25246 mRNA Translation: AAA61282.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS7120.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S13115 A25074

NCBI Reference Sequences

More...
RefSeqi
NP_003371.2, NM_003380.3
XP_006717563.1, XM_006717500.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000224237; ENSP00000224237; ENSG00000026025
ENST00000544301; ENSP00000446007; ENSG00000026025

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7431

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7431

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Wikipedia

Vimentin entry

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M14144 Genomic DNA Translation: AAA61279.1
X56134 mRNA Translation: CAA39600.1
AF328728 mRNA Translation: AAN09720.1
Z19554 mRNA Translation: CAA79613.2
AK056766 mRNA Translation: BAB71275.1 Sequence problems.
AK097336 mRNA Translation: BAC05002.1
AK290643 mRNA Translation: BAF83332.1
CR407690 mRNA Translation: CAG28618.1
AK222507 mRNA Translation: BAD96227.1
AK222602 mRNA Translation: BAD96322.1
EF445046 Genomic DNA Translation: ACA06101.1
EF445046 Genomic DNA Translation: ACA06102.1
AL133415 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86215.1
CH471072 Genomic DNA Translation: EAW86216.1
BC000163 mRNA Translation: AAH00163.2
BC030573 mRNA Translation: AAH30573.1
BC066956 mRNA Translation: AAH66956.1
X16478 mRNA Translation: CAA34499.1
M18895
, M18888, M18889, M18890, M18891, M18892, M18893, M18894 Genomic DNA Translation: AAA61281.2
M25246 mRNA Translation: AAA61282.1
CCDSiCCDS7120.1
PIRiS13115 A25074
RefSeqiNP_003371.2, NM_003380.3
XP_006717563.1, XM_006717500.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GK4X-ray2.30A/B/C/D/E/F328-411[»]
1GK6X-ray1.90A/B385-412[»]
1GK7X-ray1.40A102-138[»]
3G1EX-ray1.83A/B102-138[»]
3KLTX-ray2.70A/B/C/D263-334[»]
3S4RX-ray2.45A/B99-189[»]
3SSUX-ray2.60A/B99-189[»]
3SWKX-ray1.70A/B153-238[»]
3TRTX-ray2.30A/B261-335[»]
3UF1X-ray2.81A/B/C/D144-251[»]
4MCYX-ray2.30C66-78[»]
4MCZX-ray2.41C59-71[»]
4MD0X-ray2.19C59-71[»]
4MD5X-ray1.65C66-78[»]
4MDIX-ray2.00C66-78[»]
4MDJX-ray1.70C66-78[»]
4YPCX-ray1.44A161-243[»]
4YV3X-ray2.00A/B/C161-238[»]
5WHFX-ray2.25A/B/C/D/E/F/G/H153-238[»]
6ATFX-ray1.90C/F59-71[»]
6ATIX-ray1.98C/F59-71[»]
6BIRX-ray2.30C419-431[»]
SMRiP08670
ModBaseiSearch...

Protein-protein interaction databases

BioGridi113272, 315 interactors
CORUMiP08670
DIPiDIP-32507N
IntActiP08670, 270 interactors
MINTiP08670
STRINGi9606.ENSP00000446007

Chemistry databases

ChEMBLiCHEMBL3712854
DrugBankiDB11638 Artenimol
DB12695 Phenethyl Isothiocyanate

Protein family/group databases

MoonDBiP08670 Predicted

PTM databases

CarbonylDBiP08670
iPTMnetiP08670
PhosphoSitePlusiP08670
SwissPalmiP08670

Polymorphism and mutation databases

BioMutaiVIM
DMDMi55977767

2D gel databases

DOSAC-COBS-2DPAGEiP08670
OGPiP08670
REPRODUCTION-2DPAGEiIPI00418471
P08670
SWISS-2DPAGEiP08670
UCD-2DPAGEiP08670

Proteomic databases

CPTACiCPTAC-1017
CPTAC-1018
CPTAC-1036
CPTAC-1303
CPTAC-297
CPTAC-298
EPDiP08670
jPOSTiP08670
MassIVEiP08670
PaxDbiP08670
PeptideAtlasiP08670
PRIDEiP08670
ProteomicsDBi52153
TopDownProteomicsiP08670

Protocols and materials databases

ABCD curated depository of sequenced antibodies

More...
ABCDi
P08670

The DNASU plasmid repository

More...
DNASUi
7431
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000224237; ENSP00000224237; ENSG00000026025
ENST00000544301; ENSP00000446007; ENSG00000026025
GeneIDi7431
KEGGihsa:7431

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7431
DisGeNETi7431

GeneCards: human genes, protein and diseases

More...
GeneCardsi
VIM
HGNCiHGNC:12692 VIM
HPAiCAB000080
CAB058687
HPA001762
MalaCardsiVIM
MIMi116300 phenotype
193060 gene
neXtProtiNX_P08670
OpenTargetsiENSG00000026025
Orphaneti98984 Pulverulent cataract
PharmGKBiPA37311

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IFZ1 Eukaryota
ENOG410XRBS LUCA
GeneTreeiENSGT00940000156146
InParanoidiP08670
KOiK07606
OMAiQVINEST
OrthoDBi655109at2759
PhylomeDBiP08670
TreeFamiTF330122

Enzyme and pathway databases

ReactomeiR-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins
R-HSA-390522 Striated Muscle Contraction
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
SIGNORiP08670

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
VIM human
EvolutionaryTraceiP08670

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
Vimentin

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7431

Pharos

More...
Pharosi
P08670
PMAP-CutDBiP08670

Protein Ontology

More...
PROi
PR:P08670

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000026025 Expressed in 241 organ(s), highest expression level in dorsal root ganglion
ExpressionAtlasiP08670 baseline and differential
GenevisibleiP08670 HS

Family and domain databases

Gene3Di1.20.5.1160, 1 hit
InterProiView protein in InterPro
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR042180 IF_rod_dom_coil1B
IPR006821 Intermed_filament_DNA-bd
IPR027699 Vimentin
PANTHERiPTHR45652:SF5 PTHR45652:SF5, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PF04732 Filament_head, 1 hit
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVIME_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P08670
Secondary accession number(s): B0YJC2
, D3DRU4, Q15867, Q15868, Q15869, Q548L2, Q6LER9, Q8N850, Q96ML2, Q9NTM3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 23, 2007
Last modified: September 18, 2019
This is version 246 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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