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Protein

Kassinin

Gene
N/A
Organism
Kassina senegalensis (Senegal running frog)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

GO - Biological processi

Keywordsi

Molecular functionAmphibian defense peptide, Neuropeptide

Names & Taxonomyi

Protein namesi
Recommended name:
Kassinin
OrganismiKassina senegalensis (Senegal running frog)
Taxonomic identifieri8415 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraNeobatrachiaMicrohyloideaHyperoliidaeKassina

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
PeptideiPRO_00000443971 – 12KassininAdd BLAST12

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei12Methionine amide1 Publication1

Keywords - PTMi

Amidation

Expressioni

Tissue specificityi

Expressed by the skin glands.

Structurei

Secondary structure

112
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 11Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MYUNMR-A1-12[»]
SMRiP08611
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP08611

Family & Domainsi

Sequence similaritiesi

Belongs to the tachykinin family.Curated

Family and domain databases

InterProiView protein in InterPro
IPR013055 Tachy_Neuro_lke_CS
IPR008215 Tachykinin_dom
PfamiView protein in Pfam
PF02202 Tachykinin, 1 hit
PROSITEiView protein in PROSITE
PS00267 TACHYKININ, 1 hit

Sequencei

Sequence statusi: Complete.

Length:12
Mass (Da):1,336
Last modified:August 1, 1988 - v1
Checksum:i91757AB89DD6DAB5
GO

Sequence databases

PIRiS07206

Similar proteinsi

Entry informationi

Entry nameiTKN_KASSE
AccessioniPrimary (citable) accession number: P08611
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: April 12, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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