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Entry version 189 (26 Feb 2020)
Sequence version 2 (21 Feb 2006)
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Protein

Sulfate adenylyltransferase

Gene

MET3

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.UniRule annotation

Miscellaneous

Present with 1510 molecules/cell in log phase SD medium.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.65 mM for Sulfate1 Publication
  2. KM=0.082 mM for ATP1 Publication

    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: hydrogen sulfide biosynthesis

    This protein is involved in step 1 of the subpathway that synthesizes sulfite from sulfate.UniRule annotation
    Proteins known to be involved in the 3 steps of the subpathway in this organism are:
    1. Sulfate adenylyltransferase (MET3)
    2. Adenylyl-sulfate kinase (MET14)
    3. Phosphoadenosine phosphosulfate reductase (MET16)
    This subpathway is part of the pathway hydrogen sulfide biosynthesis, which is itself part of Sulfur metabolism.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes sulfite from sulfate, the pathway hydrogen sulfide biosynthesis and in Sulfur metabolism.

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei195SulfateUniRule annotation1 Publication1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei196UniRule annotation1 Publication1
    Active sitei197UniRule annotation1 Publication1
    Binding sitei197SulfateUniRule annotation1 Publication1
    Active sitei198UniRule annotation1 Publication1
    <p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei201Transition state stabilizerUniRule annotation1 Publication1
    Sitei204Transition state stabilizerUniRule annotation1 Publication1
    Binding sitei293Sulfate; via amide nitrogenUniRule annotation1 Publication1
    Sitei328Induces change in substrate recognition on ATP bindingUniRule annotation1 Publication1
    Binding sitei331ATP; via amide nitrogenUniRule annotation1 Publication1

    Regions

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi195 – 198ATPUniRule annotation1 Publication4
    Nucleotide bindingi289 – 292ATPUniRule annotation1 Publication4

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionNucleotidyltransferase, Transferase
    Biological processAmino-acid biosynthesis, Cysteine biosynthesis, Methionine biosynthesis
    LigandATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    MetaCyc:YJR010W-MONOMER
    YEAST:YJR010W-MONOMER

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    2.7.7.4 984

    UniPathway: a resource for the exploration and annotation of metabolic pathways

    More...
    UniPathwayi
    UPA00140;UER00204

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Sulfate adenylyltransferaseUniRule annotation (EC:2.7.7.4UniRule annotation)
    Alternative name(s):
    ATP-sulfurylaseUniRule annotation
    Methionine-requiring protein 3UniRule annotation
    Sulfate adenylate transferaseUniRule annotation
    Short name:
    SATUniRule annotation
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:MET3UniRule annotation
    Ordered Locus Names:YJR010W
    ORF Names:J1436
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

    Organism-specific databases

    Eukaryotic Pathogen Database Resources

    More...
    EuPathDBi
    FungiDB:YJR010W

    Saccharomyces Genome Database

    More...
    SGDi
    S000003771 MET3

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Keywords - Cellular componenti

    Cytoplasm

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001059541 – 511Sulfate adenylyltransferaseAdd BLAST511

    Proteomic databases

    MaxQB - The MaxQuant DataBase

    More...
    MaxQBi
    P08536

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    P08536

    PRoteomics IDEntifications database

    More...
    PRIDEi
    P08536

    Consortium for Top Down Proteomics

    More...
    TopDownProteomicsi
    P08536

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    P08536

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    Expression depends on the formation of the MET4-MET28-MET31 and MET4-MET28-MET32 complexes on its 5' upstream region.1 Publication

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Homohexamer. Dimer of trimers.

    UniRule annotation2 Publications

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    33766, 48 interactors

    Database of interacting proteins

    More...
    DIPi
    DIP-4303N

    Protein interaction database and analysis system

    More...
    IntActi
    P08536, 5 interactors

    Molecular INTeraction database

    More...
    MINTi
    P08536

    STRING: functional protein association networks

    More...
    STRINGi
    4932.YJR010W

    Miscellaneous databases

    RNAct, Protein-RNA interaction predictions for model organisms.

    More...
    RNActi
    P08536 protein

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    1511
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    P08536

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    Protein Data Bank in Europe - Knowledge Base

    More...
    PDBe-KBi
    Search...

    Miscellaneous databases

    Relative evolutionary importance of amino acids within a protein sequence

    More...
    EvolutionaryTracei
    P08536

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 167N-terminalUniRule annotation1 PublicationAdd BLAST167
    Regioni168 – 393CatalyticUniRule annotation1 PublicationAdd BLAST226
    Regioni394 – 511Required for oligomerization; adenylyl-sulfate kinase-likeUniRule annotation1 PublicationAdd BLAST118

    <p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

    The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.UniRule annotation2 Publications

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the sulfate adenylyltransferase family.UniRule annotation

    Phylogenomic databases

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_022950_1_0_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    P08536

    KEGG Orthology (KO)

    More...
    KOi
    K00958

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    HRSHEYL

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd00517 ATPS, 1 hit

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    3.40.50.620, 1 hit

    HAMAP database of protein families

    More...
    HAMAPi
    MF_03106 Sulf_adenylyltr_euk, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR025980 ATP-Sase_PUA-like_dom
    IPR027417 P-loop_NTPase
    IPR015947 PUA-like_sf
    IPR014729 Rossmann-like_a/b/a_fold
    IPR027535 Sulf_adenylyltr_euk
    IPR024951 Sulfurylase_cat_dom
    IPR002650 Sulphate_adenylyltransferase

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01747 ATP-sulfurylase, 1 hit
    PF14306 PUA_2, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF52540 SSF52540, 1 hit
    SSF88697 SSF88697, 1 hit

    TIGRFAMs; a protein family database

    More...
    TIGRFAMsi
    TIGR00339 sopT, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    P08536-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MPAPHGGILQ DLIARDALKK NELLSEAQSS DILVWNLTPR QLCDIELILN
    60 70 80 90 100
    GGFSPLTGFL NENDYSSVVT DSRLADGTLW TIPITLDVDE AFANQIKPDT
    110 120 130 140 150
    RIALFQDDEI PIAILTVQDV YKPNKTIEAE KVFRGDPEHP AISYLFNVAG
    160 170 180 190 200
    DYYVGGSLEA IQLPQHYDYP GLRKTPAQLR LEFQSRQWDR VVAFQTRNPM
    210 220 230 240 250
    HRAHRELTVR AAREANAKVL IHPVVGLTKP GDIDHHTRVR VYQEIIKRYP
    260 270 280 290 300
    NGIAFLSLLP LAMRMSGDRE AVWHAIIRKN YGASHFIVGR DHAGPGKNSK
    310 320 330 340 350
    GVDFYGPYDA QELVESYKHE LDIEVVPFRM VTYLPDEDRY APIDQIDTTK
    360 370 380 390 400
    TRTLNISGTE LRRRLRVGGE IPEWFSYPEV VKILRESNPP RPKQGFSIVL
    410 420 430 440 450
    GNSLTVSREQ LSIALLSTFL QFGGGRYYKI FEHNNKTELL SLIQDFIGSG
    460 470 480 490 500
    SGLIIPNQWE DDKDSVVGKQ NVYLLDTSSS ADIQLESADE PISHIVQKVV
    510
    LFLEDNGFFV F
    Length:511
    Mass (Da):57,725
    Last modified:February 21, 2006 - v2
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA1E7B994A9C24DFD
    GO

    <p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence CAA29702 differs from that shown. Reason: Frameshift.Curated
    The sequence CAA42726 differs from that shown. Reason: Frameshift.Curated

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti221I → T in AAU09752 (PubMed:17322287).Curated1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    X06413 Genomic DNA Translation: CAA29702.1 Frameshift.
    X60157 Genomic DNA Translation: CAA42726.1 Frameshift.
    X87611 Genomic DNA Translation: CAA60932.1
    Z49510 Genomic DNA Translation: CAA89532.1
    AY723835 Genomic DNA Translation: AAU09752.1
    BK006943 Genomic DNA Translation: DAA08801.1

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    S55198

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_012543.3, NM_001181668.3

    Genome annotation databases

    Ensembl fungal genome annotation project

    More...
    EnsemblFungii
    YJR010W_mRNA; YJR010W; YJR010W

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    853466

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    sce:YJR010W

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    X06413 Genomic DNA Translation: CAA29702.1 Frameshift.
    X60157 Genomic DNA Translation: CAA42726.1 Frameshift.
    X87611 Genomic DNA Translation: CAA60932.1
    Z49510 Genomic DNA Translation: CAA89532.1
    AY723835 Genomic DNA Translation: AAU09752.1
    BK006943 Genomic DNA Translation: DAA08801.1
    PIRiS55198
    RefSeqiNP_012543.3, NM_001181668.3

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...
    PDBei

    Protein Data Bank RCSB

    More...
    RCSB PDBi

    Protein Data Bank Japan

    More...
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    1G8FX-ray1.95A1-511[»]
    1G8GX-ray2.60A/B1-511[»]
    1G8HX-ray2.80A/B1-511[»]
    1J70X-ray2.30A/B/C1-511[»]
    1JECX-ray2.50A2-511[»]
    1JEDX-ray2.95A/B2-511[»]
    1JEEX-ray2.80A/B2-511[»]
    1R6XX-ray1.40A2-393[»]
    SMRiP08536
    ModBaseiSearch...
    PDBe-KBiSearch...

    Protein-protein interaction databases

    BioGridi33766, 48 interactors
    DIPiDIP-4303N
    IntActiP08536, 5 interactors
    MINTiP08536
    STRINGi4932.YJR010W

    PTM databases

    iPTMnetiP08536

    Proteomic databases

    MaxQBiP08536
    PaxDbiP08536
    PRIDEiP08536
    TopDownProteomicsiP08536

    Genome annotation databases

    EnsemblFungiiYJR010W_mRNA; YJR010W; YJR010W
    GeneIDi853466
    KEGGisce:YJR010W

    Organism-specific databases

    EuPathDBiFungiDB:YJR010W
    SGDiS000003771 MET3

    Phylogenomic databases

    HOGENOMiCLU_022950_1_0_1
    InParanoidiP08536
    KOiK00958
    OMAiHRSHEYL

    Enzyme and pathway databases

    UniPathwayiUPA00140;UER00204
    BioCyciMetaCyc:YJR010W-MONOMER
    YEAST:YJR010W-MONOMER
    BRENDAi2.7.7.4 984

    Miscellaneous databases

    EvolutionaryTraceiP08536

    Protein Ontology

    More...
    PROi
    PR:P08536
    RNActiP08536 protein

    Family and domain databases

    CDDicd00517 ATPS, 1 hit
    Gene3Di3.40.50.620, 1 hit
    HAMAPiMF_03106 Sulf_adenylyltr_euk, 1 hit
    InterProiView protein in InterPro
    IPR025980 ATP-Sase_PUA-like_dom
    IPR027417 P-loop_NTPase
    IPR015947 PUA-like_sf
    IPR014729 Rossmann-like_a/b/a_fold
    IPR027535 Sulf_adenylyltr_euk
    IPR024951 Sulfurylase_cat_dom
    IPR002650 Sulphate_adenylyltransferase
    PfamiView protein in Pfam
    PF01747 ATP-sulfurylase, 1 hit
    PF14306 PUA_2, 1 hit
    SUPFAMiSSF52540 SSF52540, 1 hit
    SSF88697 SSF88697, 1 hit
    TIGRFAMsiTIGR00339 sopT, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
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    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMET3_YEAST
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P08536
    Secondary accession number(s): D6VWI5, Q66R66
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
    Last sequence update: February 21, 2006
    Last modified: February 26, 2020
    This is version 189 of the entry and version 2 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure, Reference proteome

    Documents

    1. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    2. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names
    3. SIMILARITY comments
      Index of protein domains and families
    4. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
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