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Protein

4F2 cell-surface antigen heavy chain

Gene

SLC3A2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier. When associated with LAPTM4B, recruits SLC3A2 and SLC7A5 to lysosomes to promote leucine uptake into these organelles and is required for mTORC1 activation (PubMed:25998567).16 Publications

Miscellaneous

Arginine uptake is inhibited by increasing concentrations of leucine in the presence of Na+.

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=295 µM for glutamine (in the presence of NaCl)1 Publication
  2. KM=236 µM for leucine (in the presence of NaCl)1 Publication
  3. KM=120 µM for arginine (in the presence of NaCl)1 Publication
  4. KM=138 µM for arginine (in the absence of NaCl)1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    • cadherin binding Source: BHF-UCL
    • calcium:sodium antiporter activity Source: UniProtKB
    • catalytic activity Source: InterPro
    • double-stranded RNA binding Source: MGI
    • neutral amino acid transmembrane transporter activity Source: UniProtKB
    • RNA binding Source: UniProtKB

    GO - Biological processi

    • amino acid transport Source: UniProtKB
    • calcium ion transport Source: UniProtKB
    • carbohydrate metabolic process Source: InterPro
    • leukocyte migration Source: Reactome
    • L-leucine import across plasma membrane Source: UniProtKB
    • response to exogenous dsRNA Source: MGI
    • tryptophan transport Source: UniProtKB

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processAmino-acid transport, Transport

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    MetaCyc:ENSG00000168003-MONOMER

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-HSA-210991 Basigin interactions
    R-HSA-352230 Amino acid transport across the plasma membrane
    R-HSA-71240 Tryptophan catabolism

    SABIO-RK: Biochemical Reaction Kinetics Database

    More...
    SABIO-RKi
    P08195

    Protein family/group databases

    Carbohydrate-Active enZymes

    More...
    CAZyi
    GH13 Glycoside Hydrolase Family 13

    Transport Classification Database

    More...
    TCDBi
    8.A.9.2.2 the rbat transport accessory protein (rbat) family

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    4F2 cell-surface antigen heavy chain
    Short name:
    4F2hc
    Alternative name(s):
    4F2 heavy chain antigen
    Lymphocyte activation antigen 4F2 large subunit
    Solute carrier family 3 member 2
    CD_antigen: CD98
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:SLC3A2
    Synonyms:MDU1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

    Organism-specific databases

    Eukaryotic Pathogen Database Resources

    More...
    EuPathDBi
    HostDB:ENSG00000168003.16

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:11026 SLC3A2

    Online Mendelian Inheritance in Man (OMIM)

    More...
    MIMi
    158070 gene

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_P08195

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini102 – 184CytoplasmicSequence analysisAdd BLAST83
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei185 – 205Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
    Topological domaini206 – 630ExtracellularSequence analysisAdd BLAST425

    Keywords - Cellular componenti

    Cell membrane, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi210C → S: Abolishes dimerization, leucine uptake and interaction with beta-1 integrins. 3 Publications1
    Mutagenesisi431C → S: No effect on dimerization, leucine uptake or interaction with beta-1 integrins. 2 Publications1

    Organism-specific databases

    DisGeNET

    More...
    DisGeNETi
    6520

    Open Targets

    More...
    OpenTargetsi
    ENSG00000168003

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA35894

    Chemistry databases

    IUPHAR/BPS Guide to PHARMACOLOGY

    More...
    GuidetoPHARMACOLOGYi
    890

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    SLC3A2

    Domain mapping of disease mutations (DMDM)

    More...
    DMDMi
    257051063

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000643831 – 6304F2 cell-surface antigen heavy chainAdd BLAST630
    Isoform 2 (identifier: P08195-2)
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1 Publication1
    Modified residuei103PhosphoserineCombined sources1
    Modified residuei106PhosphothreonineBy similarity1
    Modified residuei134PhosphoserineCombined sources1
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki147Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
    Modified residuei165PhosphoserineCombined sources1
    Cross-linki166Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
    <p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi210Interchain (with light chain)1 Publication
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi365N-linked (GlcNAc...) asparagine3 Publications1
    Glycosylationi381N-linked (GlcNAc...) asparagine4 Publications1
    Modified residuei406Phosphoserine1 Publication1
    Modified residuei408Phosphoserine1 Publication1
    Modified residuei410Phosphoserine1 Publication1
    Glycosylationi424N-linked (GlcNAc...) (complex) asparagine4 Publications1
    Glycosylationi506N-linked (GlcNAc...) asparagine2 Publications1
    Modified residuei527Phosphoserine1 Publication1
    Modified residuei531Phosphoserine1 Publication1
    Isoform 2 (identifier: P08195-2)
    Modified residuei2N-acetylserineCombined sources1
    Modified residuei2PhosphoserineCombined sources1

    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

    Phosphorylation on Ser-406; Ser-408 or Ser-410 and on Ser-527 or Ser-531 by ecto-protein kinases favors heterotypic cell-cell interactions.1 Publication

    Keywords - PTMi

    Acetylation, Disulfide bond, Glycoprotein, Isopeptide bond, Phosphoprotein, Ubl conjugation

    Proteomic databases

    Encyclopedia of Proteome Dynamics

    More...
    EPDi
    P08195

    jPOST - Japan Proteome Standard Repository/Database

    More...
    jPOSTi
    P08195

    MaxQB - The MaxQuant DataBase

    More...
    MaxQBi
    P08195

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    P08195

    PeptideAtlas

    More...
    PeptideAtlasi
    P08195

    PRoteomics IDEntifications database

    More...
    PRIDEi
    P08195

    ProteomicsDB human proteome resource

    More...
    ProteomicsDBi
    52082
    52083 [P08195-2]
    52084 [P08195-3]
    52085 [P08195-4]

    PTM databases

    GlyConnect protein glycosylation platform

    More...
    GlyConnecti
    984

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    P08195

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    P08195

    SwissPalm database of S-palmitoylation events

    More...
    SwissPalmi
    P08195

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. During gestation, expression in the placenta was significantly stronger at full-term than at the mid-trimester stage. Expressed in HUVECS and at low levels in resting peripheral blood T-lymphocytes and quiescent fibroblasts. Also expressed in fetal liver and in the astrocytic process of primary astrocytic gliomas. Expressed in retinal endothelial cells and in the intestinal epithelial cell line C2BBe1.9 Publications

    <p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    Expression is induced in resting peripheral blood T-lymphocytes following PHA stimulation. Expression increases at the time of maximal DNA synthesis, in fibroblasts stimulated to divide. Expression and the uptake of leucine is stimulated in mononuclear, cytotrophoblast-like choriocarcinoma cells by combined treatment with PMA and calcium ionophore.3 Publications

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000168003 Expressed in 227 organ(s), highest expression level in right ovary

    CleanEx database of gene expression profiles

    More...
    CleanExi
    HS_SLC3A2

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    P08195 baseline and differential

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    P08195 HS

    Organism-specific databases

    Human Protein Atlas

    More...
    HPAi
    CAB010455
    HPA017980

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Disulfide-linked heterodimer of a glycosylated heavy chain and a non-glycosylated light chain (SLC7A5, SLC7A6, SLCA7A7, SLC7A8, SLC7A10 or SLCA7A11). Colocalizes with cadherins (By similarity). Interacts with FAM57A/CT120 and ICAM1. Constitutively and specifically associates with beta-1 integrins (alpha-2/beta-1, alpha-3/beta-1, alpha-5/beta-1 and alpha-6/beta-1), but minimally with alpha-4/beta-1. Interacts with LAPTM4B; recruits SLC3A2 and SLC7A5 to lysosomes to promote leucine uptake into these organelles and is required for mTORC1 activation (PubMed:25998567).By similarity15 Publications

    <p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

    WithEntry#Exp.IntActNotes
    sepZO523025EBI-702356,EBI-14022357From Escherichia coli.

    GO - Molecular functioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    112411, 93 interactors

    CORUM comprehensive resource of mammalian protein complexes

    More...
    CORUMi
    P08195

    Protein interaction database and analysis system

    More...
    IntActi
    P08195, 57 interactors

    Molecular INTeraction database

    More...
    MINTi
    P08195

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000367123

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    1630
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...
    PDBei

    Protein Data Bank RCSB

    More...
    RCSB PDBi

    Protein Data Bank Japan

    More...
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    2DH2X-ray2.10A212-630[»]
    2DH3X-ray2.80A/B212-630[»]

    Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

    More...
    ProteinModelPortali
    P08195

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    P08195

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    Miscellaneous databases

    Relative evolutionary importance of amino acids within a protein sequence

    More...
    EvolutionaryTracei
    P08195

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the SLC3A transporter family.Curated

    Keywords - Domaini

    Signal-anchor, Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0471 Eukaryota
    COG0366 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00940000156646

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000233529

    The HOVERGEN Database of Homologous Vertebrate Genes

    More...
    HOVERGENi
    HBG000023

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    P08195

    KEGG Orthology (KO)

    More...
    KOi
    K06519

    Database of Orthologous Groups

    More...
    OrthoDBi
    1384693at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    P08195

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    2.60.40.1180, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR006047 Glyco_hydro_13_cat_dom
    IPR013780 Glyco_hydro_b
    IPR017853 Glycoside_hydrolase_SF
    IPR031984 SLC3A2_N

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00128 Alpha-amylase, 1 hit
    PF16028 SLC3A2_N, 1 hit

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM00642 Aamy, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF51445 SSF51445, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

    This entry has 4 described isoforms and 10 potential isoforms that are computationally mapped.Show allAlign All

    Isoform 1 (identifier: P08195-1) [UniParc]FASTAAdd to basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide
            10         20         30         40         50
    MELQPPEASI AVVSIPRQLP GSHSEAGVQG LSAGDDSELG SHCVAQTGLE
    60 70 80 90 100
    LLASGDPLPS ASQNAEMIET GSDCVTQAGL QLLASSDPPA LASKNAEVTG
    110 120 130 140 150
    TMSQDTEVDM KEVELNELEP EKQPMNAASG AAMSLAGAEK NGLVKIKVAE
    160 170 180 190 200
    DEAEAAAAAK FTGLSKEELL KVAGSPGWVR TRWALLLLFW LGWLGMLAGA
    210 220 230 240 250
    VVIIVRAPRC RELPAQKWWH TGALYRIGDL QAFQGHGAGN LAGLKGRLDY
    260 270 280 290 300
    LSSLKVKGLV LGPIHKNQKD DVAQTDLLQI DPNFGSKEDF DSLLQSAKKK
    310 320 330 340 350
    SIRVILDLTP NYRGENSWFS TQVDTVATKV KDALEFWLQA GVDGFQVRDI
    360 370 380 390 400
    ENLKDASSFL AEWQNITKGF SEDRLLIAGT NSSDLQQILS LLESNKDLLL
    410 420 430 440 450
    TSSYLSDSGS TGEHTKSLVT QYLNATGNRW CSWSLSQARL LTSFLPAQLL
    460 470 480 490 500
    RLYQLMLFTL PGTPVFSYGD EIGLDAAALP GQPMEAPVML WDESSFPDIP
    510 520 530 540 550
    GAVSANMTVK GQSEDPGSLL SLFRRLSDQR SKERSLLHGD FHAFSAGPGL
    560 570 580 590 600
    FSYIRHWDQN ERFLVVLNFG DVGLSAGLQA SDLPASASLP AKADLLLSTQ
    610 620 630
    PGREEGSPLE LERLKLEPHE GLLLRFPYAA
    Length:630
    Mass (Da):67,994
    Last modified:September 1, 2009 - v3
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE427F8204CC10B0
    GO
    Isoform 2 (identifier: P08195-2) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-101: Missing.

    Show »
    Length:529
    Mass (Da):57,945
    Checksum:i82F26856737E8F31
    GO
    Isoform 3 (identifier: P08195-3) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         38-99: Missing.

    Show »
    Length:568
    Mass (Da):61,816
    Checksum:iF2B9400F95F2E1BD
    GO
    Isoform 4 (identifier: P08195-4) [UniParc]FASTAAdd to basket

    The sequence of this isoform differs from the canonical sequence as follows:
         98-98: V → VTETGFHHVSQADIEFLTSIDPTASASGSAGI

    Show »
    Length:661
    Mass (Da):71,123
    Checksum:i06C2CDFD6B1D93F5
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    J3KPF3J3KPF3_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2 hCG_2016598
    631Annotation score:

    Annotation score:2 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    F5GZS6F5GZS6_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    599Annotation score:

    Annotation score:2 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    F5H0E2F5H0E2_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    145Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    F5H867F5H867_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    135Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    H0YFS2H0YFS2_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    247Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    F5GZI0F5GZI0_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    175Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    H0YFX4H0YFX4_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    122Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    F5GZR9F5GZR9_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    47Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    F5H056F5H056_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    67Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    H0YH36H0YH36_HUMAN
    4F2 cell-surface antigen heavy chai...
    SLC3A2
    24Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti137G → E in AAA35536 (PubMed:3480538).Curated1
    Sequence conflicti158A → P in AAA51540 (PubMed:3036867).Curated1
    Sequence conflicti223A → P in AAA35536 (PubMed:3480538).Curated1
    Sequence conflicti315E → D in AAA35536 (PubMed:3480538).Curated1
    Sequence conflicti320S → F in AAA35489 (PubMed:3265470).Curated1
    Sequence conflicti372E → G in AAA35536 (PubMed:3480538).Curated1
    Sequence conflicti412 – 413GE → PQ in AAA35536 (PubMed:3480538).Curated2
    Sequence conflicti465V → L in AAA35536 (PubMed:3480538).Curated1
    Sequence conflicti481G → P in AAA35536 (PubMed:3480538).Curated1
    Sequence conflicti549G → E in AAA35489 (PubMed:3265470).Curated1
    Sequence conflicti609L → P in AAA35536 (PubMed:3480538).Curated1
    Sequence conflicti612E → G in AAA35536 (PubMed:3480538).Curated1

    <p>This subsection of the ‘Sequence’ section reports information derived from mass spectrometry experiments done on the entire protein or on biologically active derived peptide(s).<p><a href='/help/mass_spectrometry' target='_top'>More...</a></p>Mass spectrometryi

    Molecular mass is 57944.93 Da from positions 1 - 529. Determined by MALDI. 1 Publication

    Alternative sequence

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0379071 – 101Missing in isoform 2. 4 PublicationsAdd BLAST101
    Alternative sequenceiVSP_03790838 – 99Missing in isoform 3. 1 PublicationAdd BLAST62
    Alternative sequenceiVSP_03790998V → VTETGFHHVSQADIEFLTSI DPTASASGSAGI in isoform 4. 1 Publication1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    J02939 mRNA Translation: AAA52497.1
    J02769 mRNA Translation: AAA51540.1
    J03569 mRNA Translation: AAA35536.1
    M21904
    , M21898, M21899, M21900, M21901, M21902, M21903 Genomic DNA Translation: AAA35489.1
    AB018010 mRNA Translation: BAA84649.1
    AP001160 Genomic DNA No translation available.
    BC001061 mRNA Translation: AAH01061.2
    BC003000 mRNA Translation: AAH03000.2
    BE794697 mRNA No translation available.

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS31589.1 [P08195-3]
    CCDS31590.1 [P08195-2]
    CCDS8039.2 [P08195-1]

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    A28455 SAHU4F

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001012680.1, NM_001012662.2
    NP_001012682.1, NM_001012664.2 [P08195-3]
    NP_001013269.1, NM_001013251.2 [P08195-2]
    NP_002385.3, NM_002394.5 [P08195-1]

    UniGene gene-oriented nucleotide sequence clusters

    More...
    UniGenei
    Hs.502769

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000338663; ENSP00000340815; ENSG00000168003 [P08195-2]
    ENST00000377889; ENSP00000367121; ENSG00000168003 [P08195-3]
    ENST00000377890; ENSP00000367122; ENSG00000168003 [P08195-1]

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    6520

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:6520

    UCSC genome browser

    More...
    UCSCi
    uc001nwd.4 human [P08195-1]

    Keywords - Coding sequence diversityi

    Alternative splicing

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    J02939 mRNA Translation: AAA52497.1
    J02769 mRNA Translation: AAA51540.1
    J03569 mRNA Translation: AAA35536.1
    M21904
    , M21898, M21899, M21900, M21901, M21902, M21903 Genomic DNA Translation: AAA35489.1
    AB018010 mRNA Translation: BAA84649.1
    AP001160 Genomic DNA No translation available.
    BC001061 mRNA Translation: AAH01061.2
    BC003000 mRNA Translation: AAH03000.2
    BE794697 mRNA No translation available.
    CCDSiCCDS31589.1 [P08195-3]
    CCDS31590.1 [P08195-2]
    CCDS8039.2 [P08195-1]
    PIRiA28455 SAHU4F
    RefSeqiNP_001012680.1, NM_001012662.2
    NP_001012682.1, NM_001012664.2 [P08195-3]
    NP_001013269.1, NM_001013251.2 [P08195-2]
    NP_002385.3, NM_002394.5 [P08195-1]
    UniGeneiHs.502769

    3D structure databases

    Select the link destinations:
    PDBei
    RCSB PDBi
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    2DH2X-ray2.10A212-630[»]
    2DH3X-ray2.80A/B212-630[»]
    ProteinModelPortaliP08195
    SMRiP08195
    ModBaseiSearch...
    MobiDBiSearch...

    Protein-protein interaction databases

    BioGridi112411, 93 interactors
    CORUMiP08195
    IntActiP08195, 57 interactors
    MINTiP08195
    STRINGi9606.ENSP00000367123

    Chemistry databases

    GuidetoPHARMACOLOGYi890

    Protein family/group databases

    CAZyiGH13 Glycoside Hydrolase Family 13
    TCDBi8.A.9.2.2 the rbat transport accessory protein (rbat) family

    PTM databases

    GlyConnecti984
    iPTMnetiP08195
    PhosphoSitePlusiP08195
    SwissPalmiP08195

    Polymorphism and mutation databases

    BioMutaiSLC3A2
    DMDMi257051063

    Proteomic databases

    EPDiP08195
    jPOSTiP08195
    MaxQBiP08195
    PaxDbiP08195
    PeptideAtlasiP08195
    PRIDEiP08195
    ProteomicsDBi52082
    52083 [P08195-2]
    52084 [P08195-3]
    52085 [P08195-4]

    Protocols and materials databases

    The DNASU plasmid repository

    More...
    DNASUi
    6520
    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsembliENST00000338663; ENSP00000340815; ENSG00000168003 [P08195-2]
    ENST00000377889; ENSP00000367121; ENSG00000168003 [P08195-3]
    ENST00000377890; ENSP00000367122; ENSG00000168003 [P08195-1]
    GeneIDi6520
    KEGGihsa:6520
    UCSCiuc001nwd.4 human [P08195-1]

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    6520
    DisGeNETi6520
    EuPathDBiHostDB:ENSG00000168003.16

    GeneCards: human genes, protein and diseases

    More...
    GeneCardsi
    SLC3A2
    HGNCiHGNC:11026 SLC3A2
    HPAiCAB010455
    HPA017980
    MIMi158070 gene
    neXtProtiNX_P08195
    OpenTargetsiENSG00000168003
    PharmGKBiPA35894

    GenAtlas: human gene database

    More...
    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiKOG0471 Eukaryota
    COG0366 LUCA
    GeneTreeiENSGT00940000156646
    HOGENOMiHOG000233529
    HOVERGENiHBG000023
    InParanoidiP08195
    KOiK06519
    OrthoDBi1384693at2759
    PhylomeDBiP08195

    Enzyme and pathway databases

    BioCyciMetaCyc:ENSG00000168003-MONOMER
    ReactomeiR-HSA-210991 Basigin interactions
    R-HSA-352230 Amino acid transport across the plasma membrane
    R-HSA-71240 Tryptophan catabolism
    SABIO-RKiP08195

    Miscellaneous databases

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

    More...
    ChiTaRSi
    SLC3A2 human
    EvolutionaryTraceiP08195

    The Gene Wiki collection of pages on human genes and proteins

    More...
    GeneWikii
    SLC3A2

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

    More...
    GenomeRNAii
    6520

    Protein Ontology

    More...
    PROi
    PR:P08195

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSG00000168003 Expressed in 227 organ(s), highest expression level in right ovary
    CleanExiHS_SLC3A2
    ExpressionAtlasiP08195 baseline and differential
    GenevisibleiP08195 HS

    Family and domain databases

    Gene3Di2.60.40.1180, 1 hit
    InterProiView protein in InterPro
    IPR006047 Glyco_hydro_13_cat_dom
    IPR013780 Glyco_hydro_b
    IPR017853 Glycoside_hydrolase_SF
    IPR031984 SLC3A2_N
    PfamiView protein in Pfam
    PF00128 Alpha-amylase, 1 hit
    PF16028 SLC3A2_N, 1 hit
    SMARTiView protein in SMART
    SM00642 Aamy, 1 hit
    SUPFAMiSSF51445 SSF51445, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry namei4F2_HUMAN
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P08195
    Secondary accession number(s): Q13543
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
    Last sequence update: September 1, 2009
    Last modified: January 16, 2019
    This is version 215 of the entry and version 3 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human cell differentiation molecules
      CD nomenclature of surface proteins of human leucocytes and list of entries
    2. SIMILARITY comments
      Index of protein domains and families
    3. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    4. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    5. Human chromosome 11
      Human chromosome 11: entries, gene names and cross-references to MIM
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