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Protein

Beta-microseminoprotein

Gene

MSMB

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Specific receptors for this protein are found on spermatozoa and in the prostate.

Caution

Was originally thought to inhibit the secretion of FSH by pituitary cells.Curated

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Beta-microseminoprotein
Alternative name(s):
Immunoglobulin-binding factor
Short name:
IGBF
PN44
Prostate secreted seminal plasma protein
Prostate secretory protein of 94 amino acids
Short name:
PSP-94
Short name:
PSP94
Seminal plasma beta-inhibin
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MSMB
Synonyms:PRSP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000263639.5

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7372 MSMB

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
157145 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P08118

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Prostate cancer, hereditary, 13 (HPC13)
Disease susceptibility is associated with variations affecting the gene represented in this entry.
Disease descriptionA condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.
See also OMIM:611928

Organism-specific databases

DisGeNET

More...
DisGeNETi
4477

MalaCards human disease database

More...
MalaCardsi
MSMB
MIMi611928 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000263639

Orphanet; a database dedicated to information on rare diseases and orphan drugs

More...
Orphaneti
1331 Familial prostate cancer

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31177

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MSMB

Domain mapping of disease mutations (DMDM)

More...
DMDMi
131436

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 205 PublicationsAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001926821 – 114Beta-microseminoproteinAdd BLAST94

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi22 ↔ 70
Disulfide bondi38 ↔ 62
Disulfide bondi57 ↔ 93
Disulfide bondi60 ↔ 69
Disulfide bondi84 ↔ 107

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P08118

PeptideAtlas

More...
PeptideAtlasi
P08118

PRoteomics IDEntifications database

More...
PRIDEi
P08118

ProteomicsDB human proteome resource

More...
ProteomicsDBi
52068
52069 [P08118-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P08118

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P08118

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000263639 Expressed in 109 organ(s), highest expression level in prostate gland

CleanEx database of gene expression profiles

More...
CleanExi
HS_MSMB

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P08118 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB026357
HPA051257

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer; Interacts with PI16.2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
SGTAO437653EBI-10195681,EBI-347996

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
110583, 2 interactors

Protein interaction database and analysis system

More...
IntActi
P08118, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000351363

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1114
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2IZ3NMR-A21-114[»]
3IX0X-ray2.30A/B/C/D21-114[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P08118

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P08118

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P08118

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the beta-microseminoprotein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J3M2 Eukaryota
ENOG410Y4MW LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154371

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113668

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG031716

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P08118

Identification of Orthologs from Complete Genome Data

More...
OMAi
TEIICCT

Database of Orthologous Groups

More...
OrthoDBi
1519822at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P08118

TreeFam database of animal gene trees

More...
TreeFami
TF338336

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008735 PSP94

The PANTHER Classification System

More...
PANTHERi
PTHR10500 PTHR10500, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05825 PSP94, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform PSP94 (identifier: P08118-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNVLLGSVVI FATFVTLCNA SCYFIPNEGV PGDSTRKCMD LKGNKHPINS
60 70 80 90 100
EWQTDNCETC TCYETEISCC TLVSTPVGYD KDNCQRIFKK EDCKYIVVEK
110
KDPKKTCSVS EWII
Length:114
Mass (Da):12,865
Last modified:August 1, 1988 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD0B13E436D70BB1D
GO
Isoform PSP57 (identifier: P08118-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     37-77: KCMDLKGNKH...SCCTLVSTPV → MFLHLWVMTK...QKRPVLSVNG
     78-114: Missing.

Show »
Length:77
Mass (Da):8,778
Checksum:iADF30AB8D7A63C9A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti113I → G AA sequence (PubMed:6434350).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_01193517L → S. Corresponds to variant dbSNP:rs1804776Ensembl.1
Natural variantiVAR_01193625I → M. Corresponds to variant dbSNP:rs1804778Ensembl.1
Natural variantiVAR_01193752W → R. Corresponds to variant dbSNP:rs1804780Ensembl.1
Natural variantiVAR_01193853Q → R. Corresponds to variant dbSNP:rs1804468Ensembl.1
Natural variantiVAR_01193980D → A. Corresponds to variant dbSNP:rs1802774Ensembl.1
Natural variantiVAR_01194087I → T. Corresponds to variant dbSNP:rs1802771Ensembl.1
Natural variantiVAR_01194191E → G. Corresponds to variant dbSNP:rs1804469Ensembl.1
Natural variantiVAR_01194292D → G. Corresponds to variant dbSNP:rs1804461Ensembl.1
Natural variantiVAR_01194398V → L. Corresponds to variant dbSNP:rs1804464Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_00327537 – 77KCMDL…VSTPV → MFLHLWVMTKTTAKESSRRR TASISWWRRRTQKRPVLSVN G in isoform PSP57. 1 PublicationAdd BLAST41
Alternative sequenceiVSP_00327678 – 114Missing in isoform PSP57. 1 PublicationAdd BLAST37

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M15885 mRNA Translation: AAA36635.1
M34376
, M34373, M34374, M34375 Genomic DNA Translation: AAA59871.1
X57928
, X57929, X57930, X57931 Genomic DNA Translation: CAA41002.1
S67815 mRNA Translation: AAB29732.1
U22178 mRNA Translation: AAA83556.1
U78976 mRNA Translation: AAB37355.1
BT006816 mRNA Translation: AAP35462.1
CR457015 mRNA Translation: CAG33296.1
AL450342 Genomic DNA No translation available.
BC005257 mRNA Translation: AAH05257.1
AJ133356 Genomic DNA Translation: CAB39325.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS73095.1 [P08118-2]
CCDS73096.1 [P08118-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
A34567
G01730

NCBI Reference Sequences

More...
RefSeqi
NP_002434.1, NM_002443.3 [P08118-1]
NP_619540.1, NM_138634.2 [P08118-2]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.255462

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000581478; ENSP00000462641; ENSG00000263639 [P08118-2]
ENST00000582163; ENSP00000463092; ENSG00000263639 [P08118-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4477

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:4477

UCSC genome browser

More...
UCSCi
uc001jiq.5 human [P08118-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M15885 mRNA Translation: AAA36635.1
M34376
, M34373, M34374, M34375 Genomic DNA Translation: AAA59871.1
X57928
, X57929, X57930, X57931 Genomic DNA Translation: CAA41002.1
S67815 mRNA Translation: AAB29732.1
U22178 mRNA Translation: AAA83556.1
U78976 mRNA Translation: AAB37355.1
BT006816 mRNA Translation: AAP35462.1
CR457015 mRNA Translation: CAG33296.1
AL450342 Genomic DNA No translation available.
BC005257 mRNA Translation: AAH05257.1
AJ133356 Genomic DNA Translation: CAB39325.1
CCDSiCCDS73095.1 [P08118-2]
CCDS73096.1 [P08118-1]
PIRiA34567
G01730
RefSeqiNP_002434.1, NM_002443.3 [P08118-1]
NP_619540.1, NM_138634.2 [P08118-2]
UniGeneiHs.255462

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2IZ3NMR-A21-114[»]
3IX0X-ray2.30A/B/C/D21-114[»]
ProteinModelPortaliP08118
SMRiP08118
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi110583, 2 interactors
IntActiP08118, 1 interactor
STRINGi9606.ENSP00000351363

PTM databases

iPTMnetiP08118
PhosphoSitePlusiP08118

Polymorphism and mutation databases

BioMutaiMSMB
DMDMi131436

Proteomic databases

PaxDbiP08118
PeptideAtlasiP08118
PRIDEiP08118
ProteomicsDBi52068
52069 [P08118-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
4477
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000581478; ENSP00000462641; ENSG00000263639 [P08118-2]
ENST00000582163; ENSP00000463092; ENSG00000263639 [P08118-1]
GeneIDi4477
KEGGihsa:4477
UCSCiuc001jiq.5 human [P08118-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4477
DisGeNETi4477
EuPathDBiHostDB:ENSG00000263639.5

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MSMB
HGNCiHGNC:7372 MSMB
HPAiCAB026357
HPA051257
MalaCardsiMSMB
MIMi157145 gene
611928 phenotype
neXtProtiNX_P08118
OpenTargetsiENSG00000263639
Orphaneti1331 Familial prostate cancer
PharmGKBiPA31177

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410J3M2 Eukaryota
ENOG410Y4MW LUCA
GeneTreeiENSGT00940000154371
HOGENOMiHOG000113668
HOVERGENiHBG031716
InParanoidiP08118
OMAiTEIICCT
OrthoDBi1519822at2759
PhylomeDBiP08118
TreeFamiTF338336

Miscellaneous databases

EvolutionaryTraceiP08118

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
MSMB

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
4477

Protein Ontology

More...
PROi
PR:P08118

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
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Gene expression databases

BgeeiENSG00000263639 Expressed in 109 organ(s), highest expression level in prostate gland
CleanExiHS_MSMB
GenevisibleiP08118 HS

Family and domain databases

InterProiView protein in InterPro
IPR008735 PSP94
PANTHERiPTHR10500 PTHR10500, 1 hit
PfamiView protein in Pfam
PF05825 PSP94, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMSMB_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P08118
Secondary accession number(s): B1API6
, P11999, Q13125, Q6IAY9, Q9UC59
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1988
Last sequence update: August 1, 1988
Last modified: January 16, 2019
This is version 171 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
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