UniProtKB - P07864 (LDHC_HUMAN)

BLAST

>sp|P07864|LDHC_HUMAN L-lactate dehydrogenase C chain OS=Homo sapiens OX=9606 GN=LDHC PE=1 SV=4
MSTVKEQLIEKLIEDDENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKG
EMMDLQHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSI
IPAIVHYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGV
HPTSCHGWIIGEHGDSSVPLWSGVNVAGVALKTLDPKLGTDSDKEHWKNIHKQVIQSAYE
IIKLKGYTSWAIGLSVMDLVGSILKNLRRVHPVSTMVKGLYGIKEELFLSIPCVLGRNGV
SDVVKINLNSEEEALFKKSAETLWNIQKDLIF

Align
Format
Add to basket Added to basket
History
Entry version 185 (12 Sep 2018)
Sequence version 4 (23 Jan 2007)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

L-lactate dehydrogenase C chain

Gene

LDHC

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Possible role in sperm motility.

Catalytic activityⁱ

(S)-lactate + NAD⁺ = pyruvate + NADH.

Pathwayⁱ: pyruvate fermentation to lactate

This protein is involved in step 1 of the subpathway that synthesizes (S)-lactate from pyruvate.
Proteins known to be involved in this subpathway in this organism are:

L-lactate dehydrogenase C chain (LDHC), L-lactate dehydrogenase A-like 6A (LDHAL6A), L-lactate dehydrogenase A chain (LDHA), L-lactate dehydrogenase A-like 6B (LDHAL6B), L-lactate dehydrogenase B chain (LDHB), L-lactate dehydrogenase (LDHAL6A), L-lactate dehydrogenase, L-lactate dehydrogenase (LDHC), L-lactate dehydrogenase (LDHB), L-lactate dehydrogenase (LDHC), L-lactate dehydrogenase (LDHC), L-lactate dehydrogenase, L-lactate dehydrogenase (LDHB), L-lactate dehydrogenase (LDHC), L-lactate dehydrogenase (LDHAL6A), L-lactate dehydrogenase, L-lactate dehydrogenase (LDHC), L-lactate dehydrogenase (LDHC), L-lactate dehydrogenase (LDHC), L-lactate dehydrogenase (HEL-S-133P)

This subpathway is part of the pathway pyruvate fermentation to lactate, which is itself part of Fermentation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes (S)-lactate from pyruvate, the pathway pyruvate fermentation to lactate and in Fermentation.

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	99	NADBy similarity	1
Binding siteⁱ	106	SubstrateBy similarity	1
Binding siteⁱ	138	NAD or substrateBy similarity	1
Binding siteⁱ	169	SubstrateBy similarity	1
Active siteⁱ	193	Proton acceptorBy similarity	1
Binding siteⁱ	248	SubstrateBy similarity	1

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	29 – 57	NADBy similarityAdd BLAST		29

GO - Molecular functionⁱ

L-lactate dehydrogenase activity
Source: Reactome
Inferred from experimentⁱ
- 11276087
- 1996957

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

ATP biosynthetic process Source: Ensembl
carbohydrate metabolic process Source: InterPro
flagellated sperm motility Source: Ensembl
lactate biosynthetic process from pyruvate Source: Ensembl
lactate oxidation Source: Ensembl
pyruvate metabolic process Source: Reactome

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Oxidoreductase
Ligand	NAD

Enzyme and pathway databases

Reactomeⁱ	R-HSA-70268 Pyruvate metabolism
UniPathwayⁱ	UPA00554;UER00611

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: L-lactate dehydrogenase C chain (EC:1.1.1.27) Short name: LDH-C Alternative name(s): Cancer/testis antigen 32 Short name: CT32 LDH testis subunit LDH-X
Gene namesⁱ	Name:LDHC Synonyms:LDH3, LDHX
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000166796.11
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:6544 LDHC
MIMⁱ	150150 gene
neXtProtⁱ	NX_P07864

Keywords - Cellular componentⁱ

Cytoplasm

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	3948
Open Targets More...OpenTargetsⁱ	ENSG00000166796
PharmGKBⁱ	PA30328

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB00157 NADH

DrugBankⁱ

DB00157 NADH

Polymorphism and mutation databases

BioMutaⁱ	LDHC
DMDMⁱ	76363520

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000168479	1 – 332	L-lactate dehydrogenase C chainAdd BLAST		332

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	301	PhosphoserineCombined sources		1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	P07864
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P07864
PaxDbⁱ	P07864
PeptideAtlas More...PeptideAtlasⁱ	P07864
PRIDEⁱ	P07864
ProteomicsDBⁱ	52030

PTM databases

iPTMnetⁱ	P07864
PhosphoSitePlusⁱ	P07864

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000166796 Expressed in 114 organ(s), highest expression level in right testis
CleanExⁱ	HS_LDHC
ExpressionAtlasⁱ	P07864 baseline and differential
Genevisibleⁱ	P07864 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA045442

HPAⁱ

HPA045442

Interactionⁱ

Subunit structureⁱ

Homotetramer. Interacts with RABL2/RABL2A; binds preferentially to GTP-bound RABL2 (By similarity).By similarity

Protein-protein interaction databases

BioGridⁱ	110140, 24 interactors
STRINGⁱ	9606.ENSP00000280704

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P07864
SMRⁱ	P07864
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the LDH/MDH superfamily. LDH family.Curated

Phylogenomic databases

eggNOGⁱ	KOG1495 Eukaryota COG0039 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074541
HOGENOMⁱ	HOG000213793
HOVERGENⁱ	HBG000462
InParanoidⁱ	P07864
KEGG Orthology (KO) More...KOⁱ	K00016
OMAⁱ	DQWKNIH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HME
PhylomeDBⁱ	P07864
TreeFamⁱ	TF314963

Family and domain databases

Gene3Dⁱ	3.90.110.10, 1 hit
HAMAPⁱ	MF_00488 Lactate_dehydrog, 1 hit
InterProⁱ	View protein in InterPro IPR001557 L-lactate/malate_DH IPR011304 L-lactate_DH IPR018177 L-lactate_DH_AS IPR022383 Lactate/malate_DH_C IPR001236 Lactate/malate_DH_N IPR015955 Lactate_DH/Glyco_Ohase_4_C IPR036291 NAD(P)-bd_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02866 Ldh_1_C, 1 hit PF00056 Ldh_1_N, 1 hit
PIRSFⁱ	PIRSF000102 Lac_mal_DH, 1 hit
PRINTSⁱ	PR00086 LLDHDRGNASE
SUPFAMⁱ	SSF51735 SSF51735, 1 hit SSF56327 SSF56327, 1 hit
TIGRFAMsⁱ	TIGR01771 L-LDH-NAD, 1 hit
PROSITEⁱ	View protein in PROSITE PS00064 L_LDH, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show all Align All

P07864-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSTVKEQLIE KLIEDDENSQ CKITIVGTGA VGMACAISIL LKDLADELAL 
        60         70         80         90        100
VDVALDKLKG EMMDLQHGSL FFSTSKITSG KDYSVSANSR IVIVTAGARQ 
       110        120        130        140        150
QEGETRLALV QRNVAIMKSI IPAIVHYSPD CKILVVSNPV DILTYIVWKI 
       160        170        180        190        200
SGLPVTRVIG SGCNLDSARF RYLIGEKLGV HPTSCHGWII GEHGDSSVPL 
       210        220        230        240        250
WSGVNVAGVA LKTLDPKLGT DSDKEHWKNI HKQVIQSAYE IIKLKGYTSW 
       260        270        280        290        300
AIGLSVMDLV GSILKNLRRV HPVSTMVKGL YGIKEELFLS IPCVLGRNGV 
       310        320        330 
SDVVKINLNS EEEALFKKSA ETLWNIQKDL IF

Length:332

Mass (Da):36,311

Last modified:January 23, 2007 - v4

Checksum:ⁱDF7047FF5BCB101B

Computationally mapped potential isoform sequencesⁱ

There are 7 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

F5H245	F5H245_HUMAN	L-lactate dehydrogenase L-lactate dehydrogenase, EC 1.1.1.27	LDHC	318	Annotation score:
F5H5G7	F5H5G7_HUMAN	L-lactate dehydrogenase L-lactate dehydrogenase, EC 1.1.1.27	LDHC	183	Annotation score:
F5H155	F5H155_HUMAN	L-lactate dehydrogenase L-lactate dehydrogenase, EC 1.1.1.27	LDHC	225	Annotation score:
G3XAP5	G3XAP5_HUMAN	L-lactate dehydrogenase L-lactate dehydrogenase, EC 1.1.1.27	LDHC hCG_15532	241	Annotation score:
F5GZ11	F5GZ11_HUMAN	L-lactate dehydrogenase C chain L-lactate dehydrogenase C chain	LDHC	167	Annotation score:
F5GWS6	F5GWS6_HUMAN	L-lactate dehydrogenase C chain L-lactate dehydrogenase C chain	LDHC	45	Annotation score:
F5H326	F5H326_HUMAN	L-lactate dehydrogenase C chain L-lactate dehydrogenase C chain	LDHC	51	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	77	I → V in AAA59507 (PubMed:2440048).Curated	1
Sequence conflictⁱ	77	I → V in AAA59508 (PubMed:2930531).Curated	1
Sequence conflictⁱ	82	D → G in AAP37402 (PubMed:14985855).Curated	1
Sequence conflictⁱ	119	S → I in AAA59507 (PubMed:2440048).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_034068	285	E → Q. Corresponds to variant dbSNP:rs2230150Ensembl.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	J02938 mRNA Translation: AAA59507.1 AH002865 Genomic DNA Translation: AAA59508.1 U13680 mRNA Translation: AAA21348.1 AY286300 mRNA Translation: AAP37402.1 CH471064 Genomic DNA Translation: EAW68392.1 CH471064 Genomic DNA Translation: EAW68394.1 BC019249 mRNA Translation: AAH19249.3 BC064388 mRNA Translation: AAH64388.1 BC090043 mRNA Translation: AAH90043.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS7840.1
PIRⁱ	A30933 DEHULC
NCBI Reference Sequences More...RefSeqⁱ	NP_002292.1, NM_002301.4 NP_059144.1, NM_017448.3
UniGeneⁱ	Hs.654377

Genome annotation databases

Ensemblⁱ	ENST00000280704; ENSP00000280704; ENSG00000166796 ENST00000541669; ENSP00000437783; ENSG00000166796
GeneIDⁱ	3948
KEGGⁱ	hsa:3948
UCSC genome browser More...UCSCⁱ	uc001mom.5 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P07864	L-lactate dehydrogenase		HUMAN		332	UniRef100_P07864
L-lactate dehydrogenase		PANTR		332
L-lactate dehydrogenase		PANPA		332
UPI00003E6161		HUMAN		216

Protein	Similar proteins		Species	Score	Length	Source
P07864	L-lactate dehydrogenase		HUMAN		332	UniRef90_P07864
L-lactate dehydrogenase		PANTR		332
L-lactate dehydrogenase		PANPA		332
L-lactate dehydrogenase		PAPAN		332
L-lactate dehydrogenase		CERAT		332
+21

Protein	Similar proteins		Species	Score	Length	Source
P07864	L-lactate dehydrogenase C chain		FUNHE		334	UniRef50_P07864
L-lactate dehydrogenase C chain		PIG		332
L-lactate dehydrogenase B chain (Fragment)		FUNPA		322
L-lactate dehydrogenase		HUMAN		332
L-lactate dehydrogenase		PANTR		332
+152

Cross-referencesⁱ

Web resourcesⁱ

Wikipedia

Lactate dehydrogenase entry

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	J02938 mRNA Translation: AAA59507.1 AH002865 Genomic DNA Translation: AAA59508.1 U13680 mRNA Translation: AAA21348.1 AY286300 mRNA Translation: AAP37402.1 CH471064 Genomic DNA Translation: EAW68392.1 CH471064 Genomic DNA Translation: EAW68394.1 BC019249 mRNA Translation: AAH19249.3 BC064388 mRNA Translation: AAH64388.1 BC090043 mRNA Translation: AAH90043.1
CCDSⁱ	CCDS7840.1
PIRⁱ	A30933 DEHULC
RefSeqⁱ	NP_002292.1, NM_002301.4 NP_059144.1, NM_017448.3
UniGeneⁱ	Hs.654377

3D structure databases

ProteinModelPortalⁱ	P07864
SMRⁱ	P07864
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	110140, 24 interactors
STRINGⁱ	9606.ENSP00000280704

Chemistry databases

DrugBankⁱ	DB00157 NADH

DrugBankⁱ

DB00157 NADH

PTM databases

iPTMnetⁱ	P07864
PhosphoSitePlusⁱ	P07864

Polymorphism and mutation databases

BioMutaⁱ	LDHC
DMDMⁱ	76363520

Proteomic databases

EPDⁱ	P07864
MaxQBⁱ	P07864
PaxDbⁱ	P07864
PeptideAtlasⁱ	P07864
PRIDEⁱ	P07864
ProteomicsDBⁱ	52030

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	3948
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000280704; ENSP00000280704; ENSG00000166796 ENST00000541669; ENSP00000437783; ENSG00000166796
GeneIDⁱ	3948
KEGGⁱ	hsa:3948
UCSCⁱ	uc001mom.5 human

Organism-specific databases

CTDⁱ	3948
DisGeNETⁱ	3948
EuPathDBⁱ	HostDB:ENSG00000166796.11
GeneCardsⁱ	LDHC
HGNCⁱ	HGNC:6544 LDHC
HPAⁱ	HPA045442
MIMⁱ	150150 gene
neXtProtⁱ	NX_P07864
OpenTargetsⁱ	ENSG00000166796
PharmGKBⁱ	PA30328
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1495 Eukaryota COG0039 LUCA
GeneTreeⁱ	ENSGT00550000074541
HOGENOMⁱ	HOG000213793
HOVERGENⁱ	HBG000462
InParanoidⁱ	P07864
KOⁱ	K00016
OMAⁱ	DQWKNIH
OrthoDBⁱ	EOG091G0HME
PhylomeDBⁱ	P07864
TreeFamⁱ	TF314963

Enzyme and pathway databases

UniPathwayⁱ	UPA00554;UER00611
Reactomeⁱ	R-HSA-70268 Pyruvate metabolism

Miscellaneous databases

ChiTaRSⁱ	LDHC human
GenomeRNAiⁱ	3948
Protein Ontology More...PROⁱ	PR:P07864
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000166796 Expressed in 114 organ(s), highest expression level in right testis
CleanExⁱ	HS_LDHC
ExpressionAtlasⁱ	P07864 baseline and differential
Genevisibleⁱ	P07864 HS

Family and domain databases

Gene3Dⁱ	3.90.110.10, 1 hit
HAMAPⁱ	MF_00488 Lactate_dehydrog, 1 hit
InterProⁱ	View protein in InterPro IPR001557 L-lactate/malate_DH IPR011304 L-lactate_DH IPR018177 L-lactate_DH_AS IPR022383 Lactate/malate_DH_C IPR001236 Lactate/malate_DH_N IPR015955 Lactate_DH/Glyco_Ohase_4_C IPR036291 NAD(P)-bd_dom_sf
Pfamⁱ	View protein in Pfam PF02866 Ldh_1_C, 1 hit PF00056 Ldh_1_N, 1 hit
PIRSFⁱ	PIRSF000102 Lac_mal_DH, 1 hit
PRINTSⁱ	PR00086 LLDHDRGNASE
SUPFAMⁱ	SSF51735 SSF51735, 1 hit SSF56327 SSF56327, 1 hit
TIGRFAMsⁱ	TIGR01771 L-LDH-NAD, 1 hit
PROSITEⁱ	View protein in PROSITE PS00064 L_LDH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	LDHC_HUMAN
Accessionⁱ	P07864Primary (citable) accession number: P07864 Secondary accession number(s): D3DQY4, Q6GSG8, Q7Z7J4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 1, 1988
	Last sequence update:	January 23, 2007
	Last modified:	September 12, 2018
	This is version 185 of the entry and version 4 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
SIMILARITY comments
Index of protein domains and families
PATHWAY comments
Index of metabolic and biosynthesis pathways
Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P07864 (LDHC_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

L-lactate dehydrogenase C chain

LDHC

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: pyruvate fermentation to lactate

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Cytosol

Extracellular region or secreted

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

Pathwayⁱ: pyruvate fermentation to lactate

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ