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Entry version 183 (16 Oct 2019)
Sequence version 3 (01 Oct 1996)
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Protein

Kappa-casein

Gene

CSN3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMilk protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5223345 Miscellaneous transport and binding events

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Kappa-casein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CSN3
Synonyms:CASK, CSN10, CSNK
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:2446 CSN3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
601695 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P07498

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
1448

Open Targets

More...
OpenTargetsi
ENSG00000171209

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA26949

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
P07498

Protein family/group databases

Allergome; a platform for allergen knowledge

More...
Allergomei
1064 Hom s 8

Chemistry databases

ChEMBL database of bioactive drug-like small molecules

More...
ChEMBLi
CHEMBL3621024

Drug and drug target database

More...
DrugBanki
DB12010 Fostamatinib

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CSN3

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Add BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000449821 – 182Kappa-caseinAdd BLAST162

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi133O-linked (GalNAc...) threonine1 Publication1
Glycosylationi143O-linked (GalNAc...) threonine1 Publication1
Glycosylationi148O-linked (GalNAc...) threonine1 Publication1
Glycosylationi151O-linked (GalNAc...) threonine1 Publication1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei157Phosphothreonine; alternateBy similarity1
Glycosylationi157O-linked (GalNAc...) threonine; alternate1 Publication1
Glycosylationi167O-linked (GalNAc...) threonine1 Publication1
Glycosylationi169O-linked (GalNAc...) threonine1 Publication1
Glycosylationi178O-linked (GalNAc...) threonineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

The N-terminus is blocked.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei117 – 118Cleavage; by chymosin/rennin2

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
P07498

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P07498

PeptideAtlas

More...
PeptideAtlasi
P07498

PRoteomics IDEntifications database

More...
PRIDEi
P07498

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
52011

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P07498

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
308

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P07498

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P07498

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P07498

UniCarbKB; an annotated and curated database of glycan structures

More...
UniCarbKBi
P07498

Miscellaneous databases

CutDB - Proteolytic event database

More...
PMAP-CutDBi
P07498

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mammary gland specific. Secreted in milk.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000171209 Expressed in 38 organ(s), highest expression level in minor salivary gland

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P07498 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA035953
HPA035954

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heteromultimers composed of alpha-s1 casein and kappa casein linked by disulfide bonds.

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
RBPMSQ930623EBI-2602175,EBI-740322

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
107835, 8 interactors

Protein interaction database and analysis system

More...
IntActi
P07498, 7 interactors

Molecular INTeraction database

More...
MINTi
P07498

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000304822

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the kappa-casein family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JCVG Eukaryota
ENOG4111E7Q LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000009184

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111309

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P07498

KEGG Orthology (KO)

More...
KOi
K17282

Identification of Orthologs from Complete Genome Data

More...
OMAi
RPHAQIP

Database of Orthologous Groups

More...
OrthoDBi
856254at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P07498

TreeFam database of animal gene trees

More...
TreeFami
TF338369

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000117 Casein_kappa

The PANTHER Classification System

More...
PANTHERi
PTHR11470 PTHR11470, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00997 Casein_kappa, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002374 Casein_kappa, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P07498-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKSFLLVVNA LALTLPFLAV EVQNQKQPAC HENDERPFYQ KTAPYVPMYY
60 70 80 90 100
VPNSYPYYGT NLYQRRPAIA INNPYVPRTY YANPAVVRPH AQIPQRQYLP
110 120 130 140 150
NSHPPTVVRR PNLHPSFIAI PPKKIQDKII IPTINTIATV EPTPAPATEP
160 170 180
TVDSVVTPEA FSESIITSTP ETTTVAVTPP TA
Length:182
Mass (Da):20,305
Last modified:October 1, 1996 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8A1609D2D5C94895
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti25 – 27QKQ → EQK AA sequence (PubMed:4018271).Curated3
Sequence conflicti153D → N AA sequence (PubMed:4018271).Curated1
Sequence conflicti161F → T AA sequence (PubMed:7460900).Curated1
Sequence conflicti162S → T AA sequence (PubMed:4018271).Curated1
Sequence conflicti162S → T AA sequence (PubMed:7460900).Curated1
Sequence conflicti173T → P AA sequence (PubMed:4018271).Curated1
Sequence conflicti173T → P AA sequence (PubMed:7460900).Curated1
Sequence conflicti178 – 181TPPT → PTTS AA sequence (PubMed:4018271).Curated4
Sequence conflicti178 – 181TPPT → PTTS AA sequence (PubMed:7460900).Curated4

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02633875Y → C1 PublicationCorresponds to variant dbSNP:rs17850702Ensembl.1
Natural variantiVAR_026339110R → L1 PublicationCorresponds to variant dbSNP:rs1048152Ensembl.1
Natural variantiVAR_026340145A → T1 PublicationCorresponds to variant dbSNP:rs3775739Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M73628 mRNA Translation: AAA59456.1
X66417 mRNA Translation: CAA47048.1
U51899 Genomic DNA Translation: AAC50772.1
BC010935 mRNA Translation: AAH10935.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3538.1

Protein sequence database of the Protein Information Resource

More...
PIRi
JC4957 KKHU

NCBI Reference Sequences

More...
RefSeqi
NP_005203.2, NM_005212.2
XP_011529922.1, XM_011531620.2
XP_016863250.1, XM_017007761.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000304954; ENSP00000304822; ENSG00000171209

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
1448

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:1448

UCSC genome browser

More...
UCSCi
uc003hfe.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Protein Spotlight

Of buttons, digestion and glue - Issue 16 of November 2001

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M73628 mRNA Translation: AAA59456.1
X66417 mRNA Translation: CAA47048.1
U51899 Genomic DNA Translation: AAC50772.1
BC010935 mRNA Translation: AAH10935.1
CCDSiCCDS3538.1
PIRiJC4957 KKHU
RefSeqiNP_005203.2, NM_005212.2
XP_011529922.1, XM_011531620.2
XP_016863250.1, XM_017007761.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi107835, 8 interactors
IntActiP07498, 7 interactors
MINTiP07498
STRINGi9606.ENSP00000304822

Chemistry databases

ChEMBLiCHEMBL3621024
DrugBankiDB12010 Fostamatinib

Protein family/group databases

Allergomei1064 Hom s 8

PTM databases

GlyConnecti308
iPTMnetiP07498
PhosphoSitePlusiP07498
SwissPalmiP07498
UniCarbKBiP07498

Polymorphism and mutation databases

BioMutaiCSN3

Proteomic databases

MassIVEiP07498
PaxDbiP07498
PeptideAtlasiP07498
PRIDEiP07498
ProteomicsDBi52011
TopDownProteomicsiP07498

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
1448

Genome annotation databases

EnsembliENST00000304954; ENSP00000304822; ENSG00000171209
GeneIDi1448
KEGGihsa:1448
UCSCiuc003hfe.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1448
DisGeNETi1448

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CSN3
HGNCiHGNC:2446 CSN3
HPAiHPA035953
HPA035954
MIMi601695 gene
neXtProtiNX_P07498
OpenTargetsiENSG00000171209
PharmGKBiPA26949

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JCVG Eukaryota
ENOG4111E7Q LUCA
GeneTreeiENSGT00390000009184
HOGENOMiHOG000111309
InParanoidiP07498
KOiK17282
OMAiRPHAQIP
OrthoDBi856254at2759
PhylomeDBiP07498
TreeFamiTF338369

Enzyme and pathway databases

ReactomeiR-HSA-5223345 Miscellaneous transport and binding events

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CSN3 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
CSN3_(gene)

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
1448
PharosiP07498
PMAP-CutDBiP07498

Protein Ontology

More...
PROi
PR:P07498

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000171209 Expressed in 38 organ(s), highest expression level in minor salivary gland
GenevisibleiP07498 HS

Family and domain databases

InterProiView protein in InterPro
IPR000117 Casein_kappa
PANTHERiPTHR11470 PTHR11470, 1 hit
PfamiView protein in Pfam
PF00997 Casein_kappa, 1 hit
PIRSFiPIRSF002374 Casein_kappa, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCASK_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P07498
Secondary accession number(s): Q13575
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: October 1, 1996
Last modified: October 16, 2019
This is version 183 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Protein Spotlight
    Protein Spotlight articles and cited UniProtKB/Swiss-Prot entries
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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