UniProtKB - P07359 (GP1BA_HUMAN)
Platelet glycoprotein Ib alpha chain
GP1BA
Functioni
Miscellaneous
GO - Molecular functioni
- thrombin-activated receptor activity Source: UniProtKB
GO - Biological processi
- blood coagulation Source: MGI
- blood coagulation, intrinsic pathway Source: Reactome
- cell adhesion Source: MGI
- cell morphogenesis Source: Ensembl
- cell surface receptor signaling pathway Source: ProtInc
- fibrinolysis Source: UniProtKB
- platelet activation Source: UniProtKB
- platelet aggregation Source: GO_Central
- regulation of blood coagulation Source: UniProtKB
- regulation of megakaryocyte differentiation Source: Reactome
Keywordsi
Biological process | Blood coagulation, Cell adhesion, Hemostasis |
Enzyme and pathway databases
PathwayCommonsi | P07359 |
Reactomei | R-HSA-140837, Intrinsic Pathway of Fibrin Clot Formation R-HSA-430116, GP1b-IX-V activation signalling R-HSA-75892, Platelet Adhesion to exposed collagen R-HSA-76009, Platelet Aggregation (Plug Formation) R-HSA-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-9673221, Defective F9 activation |
SignaLinki | P07359 |
SIGNORi | P07359 |
Protein family/group databases
MoonDBi | P07359, Predicted |
Names & Taxonomyi
Protein namesi | Recommended name: Platelet glycoprotein Ib alpha chainShort name: GP-Ib alpha Short name: GPIb-alpha Short name: GPIbA Short name: Glycoprotein Ibalpha Alternative name(s): Antigen CD42b-alpha CD_antigen: CD42b Cleaved into the following chain: |
Gene namesi | Name:GP1BA |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:4439, GP1BA |
MIMi | 606672, gene |
neXtProti | NX_P07359 |
VEuPathDBi | HostDB:ENSG00000185245.7 |
Subcellular locationi
Other locations
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
- extracellular space Source: GO_Central
Plasma Membrane
- anchored component of external side of plasma membrane Source: Ensembl
- integral component of plasma membrane Source: ProtInc
- plasma membrane Source: MGI
Other locations
- cell surface Source: UniProtKB
- extracellular matrix Source: GO_Central
- membrane Source: MGI
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 17 – 531 | ExtracellularSequence analysisAdd BLAST | 515 | |
Transmembranei | 532 – 552 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 553 – 652 | CytoplasmicSequence analysisAdd BLAST | 100 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Involvement in diseasei
Non-arteritic anterior ischemic optic neuropathy (NAION)1 Publication
Bernard-Soulier syndrome (BSS)6 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_014206 | 73 | L → F in BSS. 1 PublicationCorresponds to variant dbSNP:rs121908063EnsemblClinVar. | 1 | |
Natural variantiVAR_005256 | 81 | C → R in BSS. 1 PublicationCorresponds to variant dbSNP:rs781541857Ensembl. | 1 | |
Natural variantiVAR_014207 | 145 | L → P in BSS. 1 PublicationCorresponds to variant dbSNP:rs771048666Ensembl. | 1 | |
Natural variantiVAR_005258 | 172 | A → V in BSS and BSSA2. 2 PublicationsCorresponds to variant dbSNP:rs121908065EnsemblClinVar. | 1 | |
Natural variantiVAR_005259 | 195 | Missing in BSS. 1 Publication | 1 | |
Natural variantiVAR_005260 | 225 | C → S in BSS. 1 PublicationCorresponds to variant dbSNP:rs1394634674EnsemblClinVar. | 1 |
Bernard-Soulier syndrome A2, autosomal dominant (BSSA2)1 Publication
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_005258 | 172 | A → V in BSS and BSSA2. 2 PublicationsCorresponds to variant dbSNP:rs121908065EnsemblClinVar. | 1 |
Pseudo-von Willebrand disease (VWDP)4 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_019657 | 249 | G → S in VWDP. 1 Publication | 1 | |
Natural variantiVAR_005261 | 249 | G → V in VWDP. 2 PublicationsCorresponds to variant dbSNP:rs121908062EnsemblClinVar. | 1 | |
Natural variantiVAR_005262 | 255 | M → V in VWDP; increased binding to vWF. 2 PublicationsCorresponds to variant dbSNP:rs121908064EnsemblClinVar. | 1 |
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 249 | G → A: No change. 1 Publication | 1 | |
Mutagenesisi | 249 | G → K or D: Decreased binding to vWF. 1 Publication | 1 | |
Mutagenesisi | 249 | G → S or V: Increased binding to vWF. 1 Publication | 1 |
Keywords - Diseasei
Bernard Soulier syndrome, Disease variant, von Willebrand diseaseOrganism-specific databases
DisGeNETi | 2811 |
MalaCardsi | GP1BA |
MIMi | 153670, phenotype 177820, phenotype 231200, phenotype 258660, phenotype |
OpenTargetsi | ENSG00000185245 |
Orphaneti | 274, Bernard-Soulier syndrome 853, Fetal and neonatal alloimmune thrombocytopenia 52530, Pseudo-von Willebrand disease |
Miscellaneous databases
Pharosi | P07359, Tbio |
Chemistry databases
DrugBanki | DB09213, Dexibuprofen DB05202, Egaptivon pegol DB01050, Ibuprofen DB05391, liposomal prostaglandin E1 |
Genetic variation databases
BioMutai | GP1BA |
DMDMi | 121531 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 16 | 1 PublicationAdd BLAST | 16 | |
ChainiPRO_0000021343 | 17 – 652 | Platelet glycoprotein Ib alpha chainAdd BLAST | 636 | |
ChainiPRO_0000021344 | 17 – 506 | Glycocalicin1 PublicationAdd BLAST | 490 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 20 ↔ 33 | 1 Publication | ||
Glycosylationi | 37 | N-linked (GlcNAc...) asparagine2 Publications | 1 | |
Glycosylationi | 175 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Disulfide bondi | 225 ↔ 264 | 1 Publication | ||
Disulfide bondi | 227 ↔ 280 | 1 Publication | ||
Modified residuei | 292 | Sulfotyrosine1 Publication | 1 | |
Modified residuei | 294 | Sulfotyrosine1 Publication | 1 | |
Modified residuei | 295 | Sulfotyrosine1 Publication | 1 | |
Glycosylationi | 308 | O-linked (GalNAc...) threonine1 Publication | 1 | |
Disulfide bondi | 526 | Interchain (with C-147 in GP1BB)1 Publication | ||
Disulfide bondi | 527 | Interchain (with C-147 in GP1BB)1 Publication | ||
Modified residuei | 629 | PhosphoserineCombined sources | 1 | |
Modified residuei | 632 | PhosphoserineCombined sources | 1 |
Post-translational modificationi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 506 – 507 | Cleavage; by ADAM171 Publication | 2 |
Keywords - PTMi
Disulfide bond, Glycoprotein, Phosphoprotein, SulfationProteomic databases
jPOSTi | P07359 |
MassIVEi | P07359 |
PaxDbi | P07359 |
PeptideAtlasi | P07359 |
PRIDEi | P07359 |
ProteomicsDBi | 17927 51999 |
PTM databases
GlyConnecti | 176, 10 N-Linked glycans (2 sites), 6 O-Linked glycans |
GlyGeni | P07359, 6 sites, 7 N-linked glycans (2 sites), 7 O-linked glycans (3 sites) |
iPTMneti | P07359 |
PhosphoSitePlusi | P07359 |
Expressioni
Gene expression databases
Bgeei | ENSG00000185245, Expressed in adrenal gland and 167 other tissues |
ExpressionAtlasi | P07359, baseline and differential |
Genevisiblei | P07359, HS |
Organism-specific databases
HPAi | ENSG00000185245, Tissue enriched (lymphoid) |
Interactioni
Subunit structurei
Two GP-Ib beta are disulfide-linked to one GP-Ib alpha. GP-IX is complexed with the GP-Ib heterodimer via a non covalent linkage (PubMed:17008541, PubMed:2070794).
Interacts with FLNB (PubMed:9651345).
Interacts with FLNA (via filamin repeats 4, 9, 12, 17, 19, 21, and 23) (PubMed:19828450).
4 Publications(Microbial infection) Interacts with Staphylococcus aureus protein SSL5.
1 PublicationBinary interactionsi
Hide detailsProtein-protein interaction databases
BioGRIDi | 109073, 19 interactors |
ComplexPortali | CPX-114, Glycoprotein Ib-IX-V complex CPX-117, Glycoprotein Ib-IX-V-Filamin-A complex |
CORUMi | P07359 |
IntActi | P07359, 13 interactors |
MINTi | P07359 |
STRINGi | 9606.ENSP00000329380 |
Miscellaneous databases
RNActi | P07359, protein |
Structurei
Secondary structure
3D structure databases
SMRi | P07359 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P07359 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 17 – 47 | LRRNTAdd BLAST | 31 | |
Repeati | 48 – 68 | LRR 1Add BLAST | 21 | |
Repeati | 72 – 93 | LRR 2Add BLAST | 22 | |
Repeati | 94 – 115 | LRR 3Add BLAST | 22 | |
Repeati | 117 – 137 | LRR 4Add BLAST | 21 | |
Repeati | 141 – 162 | LRR 5Add BLAST | 22 | |
Repeati | 165 – 186 | LRR 6Add BLAST | 22 | |
Repeati | 189 – 210 | LRR 7Add BLAST | 22 | |
Domaini | 221 – 282 | LRRCTAdd BLAST | 62 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 345 – 482 | Pro/Thr-richAdd BLAST | 138 |
Keywords - Domaini
Leucine-rich repeat, Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0619, Eukaryota |
GeneTreei | ENSGT00940000163073 |
InParanoidi | P07359 |
OMAi | FLWVRAN |
OrthoDBi | 282791at2759 |
PhylomeDBi | P07359 |
TreeFami | TF351114 |
Family and domain databases
Gene3Di | 3.80.10.10, 1 hit |
InterProi | View protein in InterPro IPR000483, Cys-rich_flank_reg_C IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR000372, LRRNT |
Pfami | View protein in Pfam PF13855, LRR_8, 1 hit PF01462, LRRNT, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 5 hits SM00082, LRRCT, 1 hit SM00013, LRRNT, 1 hit |
PROSITEi | View protein in PROSITE PS51450, LRR, 6 hits |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
10 20 30 40 50
MPLLLLLLLL PSPLHPHPIC EVSKVASHLE VNCDKRNLTA LPPDLPKDTT
60 70 80 90 100
ILHLSENLLY TFSLATLMPY TRLTQLNLDR CELTKLQVDG TLPVLGTLDL
110 120 130 140 150
SHNQLQSLPL LGQTLPALTV LDVSFNRLTS LPLGALRGLG ELQELYLKGN
160 170 180 190 200
ELKTLPPGLL TPTPKLEKLS LANNNLTELP AGLLNGLENL DTLLLQENSL
210 220 230 240 250
YTIPKGFFGS HLLPFAFLHG NPWLCNCEIL YFRRWLQDNA ENVYVWKQGV
260 270 280 290 300
DVKAMTSNVA SVQCDNSDKF PVYKYPGKGC PTLGDEGDTD LYDYYPEEDT
310 320 330 340 350
EGDKVRATRT VVKFPTKAHT TPWGLFYSWS TASLDSQMPS SLHPTQESTK
360 370 380 390 400
EQTTFPPRWT PNFTLHMESI TFSKTPKSTT EPTPSPTTSE PVPEPAPNMT
410 420 430 440 450
TLEPTPSPTT PEPTSEPAPS PTTPEPTSEP APSPTTPEPT SEPAPSPTTP
460 470 480 490 500
EPTPIPTIAT SPTILVSATS LITPKSTFLT TTKPVSLLES TKKTIPELDQ
510 520 530 540 550
PPKLRGVLQG HLESSRNDPF LHPDFCCLLP LGFYVLGLFW LLFASVVLIL
560 570 580 590 600
LLSWVGHVKP QALDSGQGAA LTTATQTTHL ELQRGRQVTV PRAWLLFLRG
610 620 630 640 650
SLPTFRSSLF LWVRPNGRVG PLVAGRRPSA LSQGRGQDLL STVSIRYSGH
SL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0C4DGZ8 | A0A0C4DGZ8_HUMAN | Glycoprotein Ib (Platelet), alpha p... | GP1BA hCG_32689 | 626 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 619 | V → L in AAH27955 (PubMed:15489334).Curated | 1 |
Polymorphismi
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_011909 | 72 | R → H1 PublicationCorresponds to variant dbSNP:rs6068Ensembl. | 1 | |
Natural variantiVAR_014206 | 73 | L → F in BSS. 1 PublicationCorresponds to variant dbSNP:rs121908063EnsemblClinVar. | 1 | |
Natural variantiVAR_005256 | 81 | C → R in BSS. 1 PublicationCorresponds to variant dbSNP:rs781541857Ensembl. | 1 | |
Natural variantiVAR_013511 | 86 | L → F1 PublicationCorresponds to variant dbSNP:rs13306411EnsemblClinVar. | 1 | |
Natural variantiVAR_014207 | 145 | L → P in BSS. 1 PublicationCorresponds to variant dbSNP:rs771048666Ensembl. | 1 | |
Natural variantiVAR_005257 | 161 | T → M in Siba(+). 4 PublicationsCorresponds to variant dbSNP:rs6065EnsemblClinVar. | 1 | |
Natural variantiVAR_005258 | 172 | A → V in BSS and BSSA2. 2 PublicationsCorresponds to variant dbSNP:rs121908065EnsemblClinVar. | 1 | |
Natural variantiVAR_005259 | 195 | Missing in BSS. 1 Publication | 1 | |
Natural variantiVAR_005260 | 225 | C → S in BSS. 1 PublicationCorresponds to variant dbSNP:rs1394634674EnsemblClinVar. | 1 | |
Natural variantiVAR_019657 | 249 | G → S in VWDP. 1 Publication | 1 | |
Natural variantiVAR_005261 | 249 | G → V in VWDP. 2 PublicationsCorresponds to variant dbSNP:rs121908062EnsemblClinVar. | 1 | |
Natural variantiVAR_011910 | 254 | A → S. Corresponds to variant dbSNP:rs382524Ensembl. | 1 | |
Natural variantiVAR_005262 | 255 | M → V in VWDP; increased binding to vWF. 2 PublicationsCorresponds to variant dbSNP:rs121908064EnsemblClinVar. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J02940 mRNA Translation: AAA52595.1 M22403 Genomic DNA Translation: AAA52596.1 AB038516 Genomic DNA Translation: BAB12038.1 AB086948 Genomic DNA Translation: BAC10305.1 AF395009 Genomic DNA Translation: AAK71325.1 AC233723 Genomic DNA No translation available. BC027955 mRNA Translation: AAH27955.1 D85894 Genomic DNA Translation: BAA12911.1 S34436 Genomic DNA Translation: AAB22152.1 S34439 Genomic DNA Translation: AAB22153.1 L39103 Genomic DNA Translation: AAA69491.1 |
CCDSi | CCDS54068.1 |
PIRi | A94174, NBHUIA I70082 |
RefSeqi | NP_000164.5, NM_000173.6 |
Genome annotation databases
Ensembli | ENST00000329125; ENSP00000329380; ENSG00000185245 |
GeneIDi | 2811 |
KEGGi | hsa:2811 |
UCSCi | uc021tnz.1, human |
Similar proteinsi
Cross-referencesi
Web resourcesi
SeattleSNPs |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | J02940 mRNA Translation: AAA52595.1 M22403 Genomic DNA Translation: AAA52596.1 AB038516 Genomic DNA Translation: BAB12038.1 AB086948 Genomic DNA Translation: BAC10305.1 AF395009 Genomic DNA Translation: AAK71325.1 AC233723 Genomic DNA No translation available. BC027955 mRNA Translation: AAH27955.1 D85894 Genomic DNA Translation: BAA12911.1 S34436 Genomic DNA Translation: AAB22152.1 S34439 Genomic DNA Translation: AAB22153.1 L39103 Genomic DNA Translation: AAA69491.1 |
CCDSi | CCDS54068.1 |
PIRi | A94174, NBHUIA I70082 |
RefSeqi | NP_000164.5, NM_000173.6 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1GWB | X-ray | 2.80 | A/B | 16-296 | [»] | |
1K13 | model | - | A | 52-216 | [»] | |
1M0Z | X-ray | 1.85 | A/B | 17-306 | [»] | |
1M10 | X-ray | 3.10 | B | 17-306 | [»] | |
1OOK | X-ray | 2.30 | G | 17-306 | [»] | |
1P8V | X-ray | 2.60 | A | 17-294 | [»] | |
1P9A | X-ray | 1.70 | G | 17-306 | [»] | |
1QYY | X-ray | 2.80 | A/G | 17-306 | [»] | |
1SQ0 | X-ray | 2.60 | B | 17-304 | [»] | |
1U0N | X-ray | 2.95 | D | 17-281 | [»] | |
2BP3 | X-ray | 2.32 | S/T | 598-619 | [»] | |
3P72 | X-ray | 1.90 | A | 17-281 | [»] | |
3PMH | X-ray | 3.20 | G | 17-306 | [»] | |
4C2A | X-ray | 2.08 | B | 17-306 | [»] | |
4C2B | X-ray | 2.80 | B/D/F/H | 17-306 | [»] | |
4CH2 | X-ray | 1.60 | P/Q | 287-300 | [»] | |
4CH8 | X-ray | 1.75 | P/Q/R/S | 287-300 | [»] | |
4MGX | X-ray | 3.16 | B | 603-611 | [»] | |
4YR6 | X-ray | 2.38 | C/F | 503-512 | [»] | |
SMRi | P07359 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 109073, 19 interactors |
ComplexPortali | CPX-114, Glycoprotein Ib-IX-V complex CPX-117, Glycoprotein Ib-IX-V-Filamin-A complex |
CORUMi | P07359 |
IntActi | P07359, 13 interactors |
MINTi | P07359 |
STRINGi | 9606.ENSP00000329380 |
Chemistry databases
DrugBanki | DB09213, Dexibuprofen DB05202, Egaptivon pegol DB01050, Ibuprofen DB05391, liposomal prostaglandin E1 |
Protein family/group databases
MoonDBi | P07359, Predicted |
PTM databases
GlyConnecti | 176, 10 N-Linked glycans (2 sites), 6 O-Linked glycans |
GlyGeni | P07359, 6 sites, 7 N-linked glycans (2 sites), 7 O-linked glycans (3 sites) |
iPTMneti | P07359 |
PhosphoSitePlusi | P07359 |
Genetic variation databases
BioMutai | GP1BA |
DMDMi | 121531 |
Proteomic databases
jPOSTi | P07359 |
MassIVEi | P07359 |
PaxDbi | P07359 |
PeptideAtlasi | P07359 |
PRIDEi | P07359 |
ProteomicsDBi | 17927 51999 |
Protocols and materials databases
ABCDi | P07359, 4 sequenced antibodies |
Antibodypediai | 2697, 900 antibodies |
DNASUi | 2811 |
Genome annotation databases
Ensembli | ENST00000329125; ENSP00000329380; ENSG00000185245 |
GeneIDi | 2811 |
KEGGi | hsa:2811 |
UCSCi | uc021tnz.1, human |
Organism-specific databases
CTDi | 2811 |
DisGeNETi | 2811 |
GeneCardsi | GP1BA |
HGNCi | HGNC:4439, GP1BA |
HPAi | ENSG00000185245, Tissue enriched (lymphoid) |
MalaCardsi | GP1BA |
MIMi | 153670, phenotype 177820, phenotype 231200, phenotype 258660, phenotype 606672, gene |
neXtProti | NX_P07359 |
OpenTargetsi | ENSG00000185245 |
Orphaneti | 274, Bernard-Soulier syndrome 853, Fetal and neonatal alloimmune thrombocytopenia 52530, Pseudo-von Willebrand disease |
VEuPathDBi | HostDB:ENSG00000185245.7 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG0619, Eukaryota |
GeneTreei | ENSGT00940000163073 |
InParanoidi | P07359 |
OMAi | FLWVRAN |
OrthoDBi | 282791at2759 |
PhylomeDBi | P07359 |
TreeFami | TF351114 |
Enzyme and pathway databases
PathwayCommonsi | P07359 |
Reactomei | R-HSA-140837, Intrinsic Pathway of Fibrin Clot Formation R-HSA-430116, GP1b-IX-V activation signalling R-HSA-75892, Platelet Adhesion to exposed collagen R-HSA-76009, Platelet Aggregation (Plug Formation) R-HSA-8936459, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function R-HSA-9673221, Defective F9 activation |
SignaLinki | P07359 |
SIGNORi | P07359 |
Miscellaneous databases
BioGRID-ORCSi | 2811, 9 hits in 993 CRISPR screens |
EvolutionaryTracei | P07359 |
GenomeRNAii | 2811 |
Pharosi | P07359, Tbio |
PROi | PR:P07359 |
RNActi | P07359, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000185245, Expressed in adrenal gland and 167 other tissues |
ExpressionAtlasi | P07359, baseline and differential |
Genevisiblei | P07359, HS |
Family and domain databases
Gene3Di | 3.80.10.10, 1 hit |
InterProi | View protein in InterPro IPR000483, Cys-rich_flank_reg_C IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR000372, LRRNT |
Pfami | View protein in Pfam PF13855, LRR_8, 1 hit PF01462, LRRNT, 1 hit |
SMARTi | View protein in SMART SM00369, LRR_TYP, 5 hits SM00082, LRRCT, 1 hit SM00013, LRRNT, 1 hit |
PROSITEi | View protein in PROSITE PS51450, LRR, 6 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GP1BA_HUMAN | |
Accessioni | P07359Primary (citable) accession number: P07359 Secondary accession number(s): E7ES66 Q9UQS4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1988 |
Last sequence update: | April 16, 2014 | |
Last modified: | April 7, 2021 | |
This is version 247 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries - Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references