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UniProtKB - P07311 (ACYP1_HUMAN)

Entry version 185 (10 Feb 2021)
Sequence version 2 (23 Jan 2007)
Previous versions | rss
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Protein

Acylphosphatase-1

Gene

ACYP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Its physiological role is not yet clear.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei24PROSITE-ProRule annotation1
Active sitei42PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • acylphosphatase activity Source: GO_Central
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		P07311

SABIO-RK: Biochemical Reaction Kinetics Database

More...SABIO-RKi		P07311

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Acylphosphatase-1 (EC:3.6.1.7)
Alternative name(s):
Acylphosphatase, erythrocyte isozyme
Acylphosphatase, organ-common type isozyme
Acylphosphate phosphohydrolase 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ACYP1
Synonyms:ACYPE
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:179, ACYP1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		600875, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_P07311

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000119640.8

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		97

Open Targets

More...OpenTargetsi		ENSG00000119640

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA24499

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		P07311, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ACYP1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001585352 – 99Acylphosphatase-1Add BLAST98

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P07311

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P07311

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		P07311

MaxQB - The MaxQuant DataBase

More...MaxQBi		P07311

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P07311

PeptideAtlas

More...PeptideAtlasi		P07311

PRoteomics IDEntifications database

More...PRIDEi		P07311

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		51984 [P07311-1]
934

Consortium for Top Down Proteomics

More...TopDownProteomicsi		P07311-1 [P07311-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P07311

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P07311

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Organ-common type isozyme is found in many different tissues.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000119640, Expressed in tendon and 230 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P07311, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P07311, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000119640, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		106612, 2 interactors

Protein interaction database and analysis system

More...IntActi		P07311, 1 interactor

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000238618

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P07311, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

199
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P07311

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P07311

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 99Acylphosphatase-likePROSITE-ProRule annotationAdd BLAST91

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the acylphosphatase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3360, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011103

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_141932_0_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P07311

Database for complete collections of gene phylogenies

More...PhylomeDBi		P07311

TreeFam database of animal gene trees

More...TreeFami		TF300288

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR020456, Acylphosphatase
IPR001792, Acylphosphatase-like_dom
IPR036046, Acylphosphatase-like_dom_sf
IPR017968, Acylphosphatase_CS

The PANTHER Classification System

More...PANTHERi		PTHR10029, PTHR10029, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00708, Acylphosphatase, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00112, ACYLPHPHTASE

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF54975, SSF54975, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00150, ACYLPHOSPHATASE_1, 1 hit
PS00151, ACYLPHOSPHATASE_2, 1 hit
PS51160, ACYLPHOSPHATASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P07311-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEGNTLISV DYEIFGKVQG VFFRKHTQAE GKKLGLVGWV QNTDRGTVQG 
        60         70         80         90 
QLQGPISKVR HMQEWLETRG SPKSHIDKAN FNNEKVILKL DYSDFQIVK
Length:99
Mass (Da):11,261
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF9F787E490BC8296
GO
Isoform 2 (identifier: P07311-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     29-99: AEGKKLGLVG...LDYSDFQIVK → EMTVENRIAETHSKSCVPVSFATSYAG

Show »
Length:55
Mass (Da):6,113
Checksum:i37822D3FA5EF8F81
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V2U7G3V2U7_HUMAN
Acylphosphatase
ACYP1
129Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V3F8G3V3F8_HUMAN
Acylphosphatase-1
ACYP1
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V597G3V597_HUMAN
Acylphosphatase-1
ACYP1
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04568829 – 99AEGKK…FQIVK → EMTVENRIAETHSKSCVPVS FATSYAG in isoform 2. 1 PublicationAdd BLAST71

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X84194 mRNA Translation: CAA58987.1
AK312101 mRNA Translation: BAG35037.1
AC007055 Genomic DNA Translation: AAD31937.1
AL049780 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81216.1
BC035568 mRNA Translation: AAH35568.1
BG614847 mRNA No translation available.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS9838.1 [P07311-1]

Protein sequence database of the Protein Information Resource

More...PIRi		S66187, QPHUE

NCBI Reference Sequences

More...RefSeqi		NP_001098.1, NM_001107.4 [P07311-1]
NP_001289545.1, NM_001302616.1 [P07311-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000238618; ENSP00000238618; ENSG00000119640 [P07311-1]
ENST00000357971; ENSP00000350655; ENSG00000119640 [P07311-2]
ENST00000555694; ENSP00000451581; ENSG00000119640 [P07311-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		97

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:97

UCSC genome browser

More...UCSCi		uc001xrf.4, human [P07311-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X84194 mRNA Translation: CAA58987.1
AK312101 mRNA Translation: BAG35037.1
AC007055 Genomic DNA Translation: AAD31937.1
AL049780 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81216.1
BC035568 mRNA Translation: AAH35568.1
BG614847 mRNA No translation available.
CCDSiCCDS9838.1 [P07311-1]
PIRiS66187, QPHUE
RefSeqiNP_001098.1, NM_001107.4 [P07311-1]
NP_001289545.1, NM_001302616.1 [P07311-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2K7JNMR-A2-99[»]
2K7KNMR-A2-99[»]
2VH7X-ray1.45A1-99[»]
2W4CX-ray1.52A1-99[»]
2W4PX-ray1.70A1-99[»]
3TOQX-ray2.00A1-99[»]
6CBUX-ray1.20A1-98[»]
SMRiP07311
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi106612, 2 interactors
IntActiP07311, 1 interactor
STRINGi9606.ENSP00000238618

PTM databases

iPTMnetiP07311
PhosphoSitePlusiP07311

Genetic variation databases

BioMutaiACYP1

Proteomic databases

EPDiP07311
jPOSTiP07311
MassIVEiP07311
MaxQBiP07311
PaxDbiP07311
PeptideAtlasiP07311
PRIDEiP07311
ProteomicsDBi51984 [P07311-1]
934
TopDownProteomicsiP07311-1 [P07311-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		25782, 191 antibodies

Genome annotation databases

EnsembliENST00000238618; ENSP00000238618; ENSG00000119640 [P07311-1]
ENST00000357971; ENSP00000350655; ENSG00000119640 [P07311-2]
ENST00000555694; ENSP00000451581; ENSG00000119640 [P07311-1]
GeneIDi97
KEGGihsa:97
UCSCiuc001xrf.4, human [P07311-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		97
DisGeNETi97

GeneCards: human genes, protein and diseases

More...GeneCardsi		ACYP1
HGNCiHGNC:179, ACYP1
HPAiENSG00000119640, Low tissue specificity
MIMi600875, gene
neXtProtiNX_P07311
OpenTargetsiENSG00000119640
PharmGKBiPA24499
VEuPathDBiHostDB:ENSG00000119640.8

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3360, Eukaryota
GeneTreeiENSGT00390000011103
HOGENOMiCLU_141932_0_1_1
InParanoidiP07311
PhylomeDBiP07311
TreeFamiTF300288

Enzyme and pathway databases

PathwayCommonsiP07311
SABIO-RKiP07311

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		97, 2 hits in 873 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ACYP1, human
EvolutionaryTraceiP07311

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		ACYP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		97
PharosiP07311, Tbio

Protein Ontology

More...PROi		PR:P07311
RNActiP07311, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000119640, Expressed in tendon and 230 other tissues
ExpressionAtlasiP07311, baseline and differential
GenevisibleiP07311, HS

Family and domain databases

InterProiView protein in InterPro
IPR020456, Acylphosphatase
IPR001792, Acylphosphatase-like_dom
IPR036046, Acylphosphatase-like_dom_sf
IPR017968, Acylphosphatase_CS
PANTHERiPTHR10029, PTHR10029, 1 hit
PfamiView protein in Pfam
PF00708, Acylphosphatase, 1 hit
PRINTSiPR00112, ACYLPHPHTASE
SUPFAMiSSF54975, SSF54975, 1 hit
PROSITEiView protein in PROSITE
PS00150, ACYLPHOSPHATASE_1, 1 hit
PS00151, ACYLPHOSPHATASE_2, 1 hit
PS51160, ACYLPHOSPHATASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiACYP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P07311
Secondary accession number(s): A6NDV8, B2R590
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: January 23, 2007
Last modified: February 10, 2021
This is version 185 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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