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Protein

Acylphosphatase-1

Gene

ACYP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Its physiological role is not yet clear.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei24PROSITE-ProRule annotation1
Active sitei42PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • acylphosphatase activity Source: GO_Central

GO - Biological processi

  • phosphate-containing compound metabolic process Source: ProtInc

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

SABIO-RK: Biochemical Reaction Kinetics Database

More...
SABIO-RKi
P07311

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Acylphosphatase-1 (EC:3.6.1.7)
Alternative name(s):
Acylphosphatase, erythrocyte isozyme
Acylphosphatase, organ-common type isozyme
Acylphosphate phosphohydrolase 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ACYP1
Synonyms:ACYPE
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000119640.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:179 ACYP1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
600875 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P07311

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000119640

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA24499

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ACYP1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001585352 – 99Acylphosphatase-1Add BLAST98

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanine1 Publication1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P07311

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P07311

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P07311

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P07311

PeptideAtlas

More...
PeptideAtlasi
P07311

PRoteomics IDEntifications database

More...
PRIDEi
P07311

ProteomicsDB human proteome resource

More...
ProteomicsDBi
51984

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P07311-1 [P07311-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P07311

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P07311

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Organ-common type isozyme is found in many different tissues.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000119640 Expressed in 218 organ(s), highest expression level in tendon

CleanEx database of gene expression profiles

More...
CleanExi
HS_ACYP1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P07311 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P07311 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA034944

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
106612, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000238618

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

199
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2K7JNMR-A2-99[»]
2K7KNMR-A2-99[»]
2VH7X-ray1.45A1-99[»]
2W4CX-ray1.52A1-99[»]
2W4PX-ray1.70A1-99[»]
3TOQX-ray2.00A1-99[»]

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P07311

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P07311

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P07311

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini9 – 99Acylphosphatase-likePROSITE-ProRule annotationAdd BLAST91

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the acylphosphatase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3360 Eukaryota
ENOG41126ER LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011103

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000292688

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG050454

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P07311

KEGG Orthology (KO)

More...
KOi
K01512

Database of Orthologous Groups

More...
OrthoDBi
1502266at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P07311

TreeFam database of animal gene trees

More...
TreeFami
TF300288

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020456 Acylphosphatase
IPR001792 Acylphosphatase-like_dom
IPR036046 Acylphosphatase-like_dom_sf
IPR017968 Acylphosphatase_CS

The PANTHER Classification System

More...
PANTHERi
PTHR10029 PTHR10029, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00708 Acylphosphatase, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00112 ACYLPHPHTASE

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54975 SSF54975, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00150 ACYLPHOSPHATASE_1, 1 hit
PS00151 ACYLPHOSPHATASE_2, 1 hit
PS51160 ACYLPHOSPHATASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: P07311-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEGNTLISV DYEIFGKVQG VFFRKHTQAE GKKLGLVGWV QNTDRGTVQG
60 70 80 90
QLQGPISKVR HMQEWLETRG SPKSHIDKAN FNNEKVILKL DYSDFQIVK
Length:99
Mass (Da):11,261
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF9F787E490BC8296
GO
Isoform 2 (identifier: P07311-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     29-99: AEGKKLGLVG...LDYSDFQIVK → EMTVENRIAETHSKSCVPVSFATSYAG

Note: No experimental confirmation available.
Show »
Length:55
Mass (Da):6,113
Checksum:i37822D3FA5EF8F81
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V2U7G3V2U7_HUMAN
Acylphosphatase
ACYP1
129Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V3F8G3V3F8_HUMAN
Acylphosphatase-1
ACYP1
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V597G3V597_HUMAN
Acylphosphatase-1
ACYP1
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_04568829 – 99AEGKK…FQIVK → EMTVENRIAETHSKSCVPVS FATSYAG in isoform 2. 1 PublicationAdd BLAST71

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X84194 mRNA Translation: CAA58987.1
AK312101 mRNA Translation: BAG35037.1
AC007055 Genomic DNA Translation: AAD31937.1
AL049780 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81216.1
BC035568 mRNA Translation: AAH35568.1
BG614847 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9838.1 [P07311-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
S66187 QPHUE

NCBI Reference Sequences

More...
RefSeqi
NP_001098.1, NM_001107.4 [P07311-1]
NP_001289545.1, NM_001302616.1 [P07311-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.18573

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000238618; ENSP00000238618; ENSG00000119640 [P07311-1]
ENST00000357971; ENSP00000350655; ENSG00000119640 [P07311-2]
ENST00000555694; ENSP00000451581; ENSG00000119640 [P07311-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
97

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:97

UCSC genome browser

More...
UCSCi
uc001xrf.4 human [P07311-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X84194 mRNA Translation: CAA58987.1
AK312101 mRNA Translation: BAG35037.1
AC007055 Genomic DNA Translation: AAD31937.1
AL049780 Genomic DNA No translation available.
CH471061 Genomic DNA Translation: EAW81216.1
BC035568 mRNA Translation: AAH35568.1
BG614847 mRNA No translation available.
CCDSiCCDS9838.1 [P07311-1]
PIRiS66187 QPHUE
RefSeqiNP_001098.1, NM_001107.4 [P07311-1]
NP_001289545.1, NM_001302616.1 [P07311-1]
UniGeneiHs.18573

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2K7JNMR-A2-99[»]
2K7KNMR-A2-99[»]
2VH7X-ray1.45A1-99[»]
2W4CX-ray1.52A1-99[»]
2W4PX-ray1.70A1-99[»]
3TOQX-ray2.00A1-99[»]
ProteinModelPortaliP07311
SMRiP07311
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi106612, 1 interactor
STRINGi9606.ENSP00000238618

PTM databases

iPTMnetiP07311
PhosphoSitePlusiP07311

Polymorphism and mutation databases

BioMutaiACYP1

Proteomic databases

EPDiP07311
jPOSTiP07311
MaxQBiP07311
PaxDbiP07311
PeptideAtlasiP07311
PRIDEiP07311
ProteomicsDBi51984
TopDownProteomicsiP07311-1 [P07311-1]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000238618; ENSP00000238618; ENSG00000119640 [P07311-1]
ENST00000357971; ENSP00000350655; ENSG00000119640 [P07311-2]
ENST00000555694; ENSP00000451581; ENSG00000119640 [P07311-1]
GeneIDi97
KEGGihsa:97
UCSCiuc001xrf.4 human [P07311-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
97
EuPathDBiHostDB:ENSG00000119640.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ACYP1
HGNCiHGNC:179 ACYP1
HPAiHPA034944
MIMi600875 gene
neXtProtiNX_P07311
OpenTargetsiENSG00000119640
PharmGKBiPA24499

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3360 Eukaryota
ENOG41126ER LUCA
GeneTreeiENSGT00390000011103
HOGENOMiHOG000292688
HOVERGENiHBG050454
InParanoidiP07311
KOiK01512
OrthoDBi1502266at2759
PhylomeDBiP07311
TreeFamiTF300288

Enzyme and pathway databases

SABIO-RKiP07311

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ACYP1 human
EvolutionaryTraceiP07311

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
ACYP1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
97

Protein Ontology

More...
PROi
PR:P07311

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000119640 Expressed in 218 organ(s), highest expression level in tendon
CleanExiHS_ACYP1
ExpressionAtlasiP07311 baseline and differential
GenevisibleiP07311 HS

Family and domain databases

InterProiView protein in InterPro
IPR020456 Acylphosphatase
IPR001792 Acylphosphatase-like_dom
IPR036046 Acylphosphatase-like_dom_sf
IPR017968 Acylphosphatase_CS
PANTHERiPTHR10029 PTHR10029, 1 hit
PfamiView protein in Pfam
PF00708 Acylphosphatase, 1 hit
PRINTSiPR00112 ACYLPHPHTASE
SUPFAMiSSF54975 SSF54975, 1 hit
PROSITEiView protein in PROSITE
PS00150 ACYLPHOSPHATASE_1, 1 hit
PS00151 ACYLPHOSPHATASE_2, 1 hit
PS51160 ACYLPHOSPHATASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiACYP1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P07311
Secondary accession number(s): A6NDV8, B2R590
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1988
Last sequence update: January 23, 2007
Last modified: January 16, 2019
This is version 173 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
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