UniProtKB - P06993 (MALT_ECOLI)

BLAST

>sp|P06993|MALT_ECOLI HTH-type transcriptional regulator MalT OS=Escherichia coli (strain K12) OX=83333 GN=malT PE=1 SV=2
MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIG
WYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWH
SPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIG
SQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSA
RRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEE
IERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEA
IHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQ
SQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELP
PGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFA
QGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVL
SSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYW
QMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARS
LRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQ
LIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQRE
WQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYG
V

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History
Entry version 168 (10 Oct 2018)
Sequence version 2 (19 Jul 2003)
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Protein

HTH-type transcriptional regulator MalT

Gene

malT

Organism

Escherichia coli (strain K12)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides (PubMed:7040340, PubMed:3305511, PubMed:2538630, PubMed:2524384). Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box (5'-GGA[TG]GA-3') (PubMed:2538630, PubMed:2524384). Displays weak ATPase activity, but this activity is not required for promoter binding (PubMed:2524384).4 Publications

Miscellaneous

A study on malT mutants has shown that some of them became nearly completely resistant to Aes repression while still being sensitive to MalY. These mutations are located at positions 38, 220, 243, and 359, most likely defining the interaction patch with Aes on the three-dimensional structure of MalT.1 Publication

Activity regulationⁱ

Activated by ATP and maltotriose, which are both required for DNA binding (PubMed:3305511, PubMed:2524384). Negatively regulated by MalY, MalK and Aes, which bind to MalT and block maltotriose activation (PubMed:9822819, PubMed:10692154, PubMed:11867639).5 Publications

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	39 – 46	ATPUniRule annotation		8
DNA bindingⁱ	853 – 872	H-T-H motifUniRule annotationAdd BLAST		20

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-UniRule
DNA binding Source: UniProtKB-KW
DNA-binding transcription factor activity Source: UniProtKB-UniRule
identical protein binding
Source: IntAct
Inferred from physical interactionⁱ
- 20693326
- 24561554
trisaccharide binding
Source: EcoCyc
Inferred from mutant phenotypeⁱ
- 20545845

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbohydrate metabolic process Source: UniProtKB-KW
positive regulation of carbohydrate metabolic process Source: UniProtKB-UniRule
positive regulation of transcription, DNA-templated Source: UniProtKB-UniRule
transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Activator, DNA-binding
Biological process	Carbohydrate metabolism, Transcription, Transcription regulation
Ligand	ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCycⁱ	EcoCyc:PD00237 MetaCyc:PD00237

BioCycⁱ

EcoCyc:PD00237
MetaCyc:PD00237

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: HTH-type transcriptional regulator MalTUniRule annotationCurated Alternative name(s): ATP-dependent transcriptional activator MalT1 PublicationUniRule annotation
Gene namesⁱ	Name:malT1 PublicationUniRule annotation Synonyms:malA Ordered Locus Names:b3418, JW3381
Organismⁱ	Escherichia coli (strain K12)
Taxonomic identifierⁱ	83333 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › Escherichia coli
Proteomesⁱ	UP000000318 Componentⁱ: Chromosome UP000000625 Componentⁱ: Chromosome

Organism-specific databases

EcoGeneⁱ	EG10562 malT

EcoGeneⁱ

EG10562 malT

Pathology & Biotechⁱ

Chemistry databases

Drug and drug target database More...DrugBankⁱ	DB03793 Benzoic Acid

DrugBankⁱ

DB03793 Benzoic Acid

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000184163	1 – 901	HTH-type transcriptional regulator MalTAdd BLAST		901

Proteomic databases

PaxDbⁱ	P06993
PRIDEⁱ	P06993

Expressionⁱ

Inductionⁱ

Expression is induced by the cAMP-activated global transcriptional regulator CRP.1 Publication

Interactionⁱ

Subunit structureⁱ

Monomer in solution (PubMed:3305511, PubMed:10559195). Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose (PubMed:10559195). Interacts with MalY, MalK and Aes, all of which negatively regulate MalT activity by antagonizing maltotriose binding (PubMed:9822819, PubMed:10692154, PubMed:11867639).5 Publications

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
itself		2	EBI-542934,EBI-542934
dnaJ	P08622	5	EBI-542934,EBI-545285
fixB	P31574	3	EBI-542934,EBI-554030
fliJ	P52613	3	EBI-542934,EBI-554036
hslR	P0ACG8	2	EBI-542934,EBI-562824
rlmN	P36979	3	EBI-542934,EBI-559071

GO - Molecular functionⁱ

identical protein binding
Source: IntAct
Inferred from physical interactionⁱ
- 20693326
- 24561554

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	4261189, 24 interactors 852230, 1 interactor
Database of interacting proteins More...DIPⁱ	DIP-10149N
IntActⁱ	P06993, 30 interactors
STRINGⁱ	316385.ECDH10B_3593

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	442 – 461	Combined sources	20
Helixⁱ	465 – 477	Combined sources	13
Helixⁱ	484 – 501	Combined sources	18
Helixⁱ	504 – 520	Combined sources	17
Helixⁱ	524 – 540	Combined sources	17
Helixⁱ	544 – 560	Combined sources	17
Helixⁱ	568 – 582	Combined sources	15
Helixⁱ	586 – 599	Combined sources	14
Turnⁱ	600 – 602	Combined sources	3
Helixⁱ	605 – 608	Combined sources	4
Helixⁱ	609 – 622	Combined sources	14
Helixⁱ	625 – 639	Combined sources	15
Helixⁱ	646 – 662	Combined sources	17
Helixⁱ	666 – 675	Combined sources	10
Helixⁱ	685 – 687	Combined sources	3
Helixⁱ	688 – 700	Combined sources	13
Helixⁱ	704 – 720	Combined sources	17
Helixⁱ	724 – 741	Combined sources	18
Helixⁱ	744 – 761	Combined sources	18
Helixⁱ	765 – 768	Combined sources	4
Helixⁱ	771 – 783	Combined sources	13
Helixⁱ	789 – 802	Combined sources	14

Show more details

3D structure databases

ProteinModelPortalⁱ	P06993
SMRⁱ	P06993
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ

P06993

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	829 – 894	HTH luxR-typeUniRule annotationAdd BLAST		66

Region

Feature key	Position(s)	DescriptionActions	Length
Regionⁱ	1 – 241	DT11 PublicationAdd BLAST	241
Regionⁱ	242 – 436	DT21 PublicationAdd BLAST	195
Regionⁱ	437 – 806	DT32 PublicationsAdd BLAST	370
Regionⁱ	807 – 901	DT41 PublicationAdd BLAST	95

Domainⁱ

Consists of four structural domains: the ATP binding site resides in domain I (DT1); DT3 binds the positive effector maltotriose with a low affinity, and the binding affinity is increased in the presence of DT2; the C-terminal domain DT4 contains the helix-turn-helix DNA binding motif. DT1 also contains the region that interacts with MalY (but not with MalK), and the binding site for Aes is also likely to be contained in the N-terminal portion of MalT encompassing DT1 and DT2 (PubMed:12003949). Domain DT3 may mediate oligomerization (PubMed:11709169).2 Publications

Sequence similaritiesⁱ

Belongs to the MalT family.UniRule annotationCurated

Phylogenomic databases

eggNOGⁱ	ENOG41061ZR Bacteria COG2909 LUCA
HOGENOMⁱ	HOG000218261
InParanoidⁱ	P06993
KEGG Orthology (KO) More...KOⁱ	K03556
OMAⁱ	SDWVSNA
PhylomeDBⁱ	P06993

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd06170 LuxR_C_like, 1 hit
Gene3Dⁱ	1.10.10.10, 1 hit 1.25.40.10, 1 hit
HAMAPⁱ	MF_01247 HTH_type_MalT, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR016032 Sig_transdc_resp-reg_C-effctor IPR011990 TPR-like_helical_dom_sf IPR023768 Tscrpt_reg_HTH_MalT IPR000792 Tscrpt_reg_LuxR_C IPR036388 WH-like_DNA-bd_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00196 GerE, 1 hit
PRINTSⁱ	PR00038 HTHLUXR
SMARTⁱ	View protein in SMART SM00421 HTH_LUXR, 1 hit
SUPFAMⁱ	SSF46894 SSF46894, 1 hit SSF48452 SSF48452, 1 hit SSF52540 SSF52540, 1 hit
PROSITEⁱ	View protein in PROSITE PS00622 HTH_LUXR_1, 1 hit PS50043 HTH_LUXR_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P06993-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLIPSKLSRP VRLDHTVVRE RLLAKLSGAN NFRLALITSP AGYGKTTLIS 
        60         70         80         90        100
QWAAGKNDIG WYSLDEGDNQ QERFASYLIA AVQQATNGHC AICETMAQKR 
       110        120        130        140        150
QYASLTSLFA QLFIELAEWH SPLYLVIDDY HLITNPVIHE SMRFFIRHQP 
       160        170        180        190        200
ENLTLVVLSR NLPQLGIANL RVRDQLLEIG SQQLAFTHQE AKQFFDCRLS 
       210        220        230        240        250
SPIEAAESSR ICDDVSGWAT ALQLIALSAR QNTHSAHKSA RRLAGINASH 
       260        270        280        290        300
LSDYLVDEVL DNVDLATRHF LLKSAILRSM NDALITRVTG EENGQMRLEE 
       310        320        330        340        350
IERQGLFLQR MDDTGEWFCY HPLFGNFLRQ RCQWELAAEL PEIHRAAAES 
       360        370        380        390        400
WMAQGFPSEA IHHALAAGDA LMLRDILLNH AWSLFNHSEL SLLEESLKAL 
       410        420        430        440        450
PWDSLLENPQ LVLLQAWLMQ SQHRYGEVNT LLARAEHEIK DIREDTMHAE 
       460        470        480        490        500
FNALRAQVAI NDGNPDEAER LAKLALEELP PGWFYSRIVA TSVLGEVLHC 
       510        520        530        540        550
KGELTRSLAL MQQTEQMARQ HDVWHYALWS LIQQSEILFA QGFLQTAWET 
       560        570        580        590        600
QEKAFQLINE QHLEQLPMHE FLVRIRAQLL WAWARLDEAE ASARSGIEVL 
       610        620        630        640        650
SSYQPQQQLQ CLAMLIQCSL ARGDLDNARS QLNRLENLLG NGKYHSDWIS 
       660        670        680        690        700
NANKVRVIYW QMTGDKAAAA NWLRHTAKPE FANNHFLQGQ WRNIARAQIL 
       710        720        730        740        750
LGEFEPAEIV LEELNENARS LRLMSDLNRN LLLLNQLYWQ AGRKSDAQRV 
       760        770        780        790        800
LLDALKLANR TGFISHFVIE GEAMAQQLRQ LIQLNTLPEL EQHRAQRILR 
       810        820        830        840        850
EINQHHRHKF AHFDENFVER LLNHPEVPEL IRTSPLTQRE WQVLGLIYSG 
       860        870        880        890        900
YSNEQIAGEL EVAATTIKTH IRNLYQKLGV AHRQDAVQHA QQLLKMMGYG 

V

Length:901

Mass (Da):103,118

Last modified:July 19, 2003 - v2

Checksum:ⁱ9B27CE0F632AD417

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	192 – 193	KQ → NE in AAA83888 (PubMed:3015733).Curated		2
Sequence conflictⁱ	192 – 193	KQ → NE in AAA58216 (PubMed:3015733).Curated		2

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M13585 Genomic DNA Translation: AAA83888.1 U18997 Genomic DNA Translation: AAA58216.1 Sequence problems. U00096 Genomic DNA Translation: AAC76443.1 AP009048 Genomic DNA Translation: BAE77873.1 M24342 Genomic DNA Translation: AAA24107.2 V00304 Genomic DNA Translation: CAA23583.1 X02003 Genomic DNA Translation: CAA26034.1
PIRⁱ	E65137 RGECMT
NCBI Reference Sequences More...RefSeqⁱ	NP_417877.1, NC_000913.3 WP_000906961.1, NZ_CP014272.1

Genome annotation databases

EnsemblBacteriaⁱ	AAC76443; AAC76443; b3418 BAE77873; BAE77873; BAE77873
GeneIDⁱ	947921
KEGGⁱ	ecj:JW3381 eco:b3418
PATRICⁱ	fig\|1411691.4.peg.3310

Protein	Similar proteins		Species	Score	Length	Source
P06993	HTH-type transcriptional regulator MalT		ECOBW		901	UniRef100_C4ZVX0
HTH-type transcriptional regulator MalT		ECODH		901
HTH-type transcriptional regulator MalT		ECOHS		901
HTH-type transcriptional regulator MalT		ECOLX		901
HTH-type transcriptional regulator MalT		Escherichia coli HVH 50 (4-2593475)		901
+31

Protein	Similar proteins		Species	Score	Length	Source
P06993	HTH-type transcriptional regulator MalT		SALTY		901	UniRef90_Q8ZLI3
HTH-type transcriptional regulator MalT		SALDC		902
HTH-type transcriptional regulator MalT		SALG2		901
HTH-type transcriptional regulator MalT		CITK8		901
HTH-type transcriptional regulator MalT		ECO24		901
+1901

Protein	Similar proteins		Species	Score	Length	Source
P06993	HTH-type transcriptional regulator MalT		SALTY		901	UniRef50_Q8ZLI3
HTH-type transcriptional regulator MalT		SALDC		902
HTH-type transcriptional regulator MalT		SALAR		901
HTH-type transcriptional regulator MalT		ECOLC		901
HTH-type transcriptional regulator MalT		ECO7I		901
+2158

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M13585 Genomic DNA Translation: AAA83888.1 U18997 Genomic DNA Translation: AAA58216.1 Sequence problems. U00096 Genomic DNA Translation: AAC76443.1 AP009048 Genomic DNA Translation: BAE77873.1 M24342 Genomic DNA Translation: AAA24107.2 V00304 Genomic DNA Translation: CAA23583.1 X02003 Genomic DNA Translation: CAA26034.1
PIRⁱ	E65137 RGECMT
RefSeqⁱ	NP_417877.1, NC_000913.3 WP_000906961.1, NZ_CP014272.1

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1HZ4	X-ray	1.45	A	437-806	[»]
ProteinModelPortalⁱ	P06993
SMRⁱ	P06993
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	4261189, 24 interactors 852230, 1 interactor
DIPⁱ	DIP-10149N
IntActⁱ	P06993, 30 interactors
STRINGⁱ	316385.ECDH10B_3593

Chemistry databases

DrugBankⁱ	DB03793 Benzoic Acid

DrugBankⁱ

DB03793 Benzoic Acid

Proteomic databases

PaxDbⁱ	P06993
PRIDEⁱ	P06993

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAC76443; AAC76443; b3418 BAE77873; BAE77873; BAE77873
GeneIDⁱ	947921
KEGGⁱ	ecj:JW3381 eco:b3418
PATRICⁱ	fig\|1411691.4.peg.3310

Organism-specific databases

EchoBASEⁱ	EB0557
EcoGeneⁱ	EG10562 malT

Phylogenomic databases

eggNOGⁱ	ENOG41061ZR Bacteria COG2909 LUCA
HOGENOMⁱ	HOG000218261
InParanoidⁱ	P06993
KOⁱ	K03556
OMAⁱ	SDWVSNA
PhylomeDBⁱ	P06993

Enzyme and pathway databases

BioCycⁱ	EcoCyc:PD00237 MetaCyc:PD00237

BioCycⁱ

EcoCyc:PD00237
MetaCyc:PD00237

Miscellaneous databases

EvolutionaryTraceⁱ	P06993
Protein Ontology More...PROⁱ	PR:P06993

Family and domain databases

CDDⁱ	cd06170 LuxR_C_like, 1 hit
Gene3Dⁱ	1.10.10.10, 1 hit 1.25.40.10, 1 hit
HAMAPⁱ	MF_01247 HTH_type_MalT, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR016032 Sig_transdc_resp-reg_C-effctor IPR011990 TPR-like_helical_dom_sf IPR023768 Tscrpt_reg_HTH_MalT IPR000792 Tscrpt_reg_LuxR_C IPR036388 WH-like_DNA-bd_sf
Pfamⁱ	View protein in Pfam PF00196 GerE, 1 hit
PRINTSⁱ	PR00038 HTHLUXR
SMARTⁱ	View protein in SMART SM00421 HTH_LUXR, 1 hit
SUPFAMⁱ	SSF46894 SSF46894, 1 hit SSF48452 SSF48452, 1 hit SSF52540 SSF52540, 1 hit
PROSITEⁱ	View protein in PROSITE PS00622 HTH_LUXR_1, 1 hit PS50043 HTH_LUXR_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MALT_ECOLI
Accessionⁱ	P06993Primary (citable) accession number: P06993 Secondary accession number(s): Q2M783
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 1, 1988
	Last sequence update:	July 19, 2003
	Last modified:	October 10, 2018
	This is version 168 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene

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UniProtKB - P06993 (MALT_ECOLI)

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HTH-type transcriptional regulator MalT

malT

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ