Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Recombinase cre

Gene

cre

Organism
Escherichia phage P1 (Bacteriophage P1)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalyzes site-specific recombination between two 34-base-pair LOXP sites. Its role is to maintain the phage genome as a monomeric unit-copy plasmid in the lysogenic state.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei1731
Active sitei2891
Active sitei2921
Active sitei324O-(3'-phospho-DNA)-tyrosine intermediate1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDNA integration, DNA recombination

Names & Taxonomyi

Protein namesi
Recommended name:
Recombinase cre
Gene namesi
Name:cre
OrganismiEscherichia phage P1 (Bacteriophage P1)
Taxonomic identifieri10678 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeP1virus
Virus hostiEnterobacteriaceae [TaxID: 543]
Proteomesi
  • UP000008091 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001975291 – 343Recombinase creAdd BLAST343

Interactioni

Subunit structurei

Homotetramer when bound to DNA.

Structurei

Secondary structure

1343
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP06956
SMRiP06956
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP06956

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family.Curated

Family and domain databases

Gene3Di1.10.150.130, 1 hit
1.10.443.10, 1 hit
InterProiView protein in InterPro
IPR011010 DNA_brk_join_enz
IPR013762 Integrase-like_cat_sf
IPR002104 Integrase_catalytic
IPR010998 Integrase_recombinase_N
PfamiView protein in Pfam
PF00589 Phage_integrase, 1 hit
SUPFAMiSSF56349 SSF56349, 1 hit

Sequencei

Sequence statusi: Complete.

P06956-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNLLTVHQN LPALPVDATS DEVRKNLMDM FRDRQAFSEH TWKMLLSVCR
60 70 80 90 100
SWAAWCKLNN RKWFPAEPED VRDYLLYLQA RGLAVKTIQQ HLGQLNMLHR
110 120 130 140 150
RSGLPRPSDS NAVSLVMRRI RKENVDAGER AKQALAFERT DFDQVRSLME
160 170 180 190 200
NSDRCQDIRN LAFLGIAYNT LLRIAEIARI RVKDISRTDG GRMLIHIGRT
210 220 230 240 250
KTLVSTAGVE KALSLGVTKL VERWISVSGV ADDPNNYLFC RVRKNGVAAP
260 270 280 290 300
SATSQLSTRA LEGIFEATHR LIYGAKDDSG QRYLAWSGHS ARVGAARDMA
310 320 330 340
RAGVSIPEIM QAGGWTNVNI VMNYIRNLDS ETGAMVRLLE DGD
Length:343
Mass (Da):38,540
Last modified:January 1, 1988 - v1
Checksum:iA05AC4300003FF34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03453 Genomic DNA Translation: CAA27178.1
AF234172 Genomic DNA Translation: AAQ13978.1
PIRiB24836 RGBPP1
RefSeqiYP_006472.1, NC_005856.1

Genome annotation databases

GeneIDi2777477
KEGGivg:2777477

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X03453 Genomic DNA Translation: CAA27178.1
AF234172 Genomic DNA Translation: AAQ13978.1
PIRiB24836 RGBPP1
RefSeqiYP_006472.1, NC_005856.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1CRXX-ray2.40A/B20-341[»]
1DRGX-ray2.55A21-343[»]
1F44X-ray2.05A20-343[»]
1KBUX-ray2.20A/B1-343[»]
1MA7X-ray2.30A/B1-343[»]
1NZBX-ray3.10A/B/E/F1-343[»]
1OUQX-ray3.20A/B/E/F1-343[»]
1PVPX-ray2.35A/B2-343[»]
1PVQX-ray2.75A/B2-343[»]
1PVRX-ray2.65A/B2-343[»]
1Q3UX-ray2.90A/B/E/F1-343[»]
1Q3VX-ray2.91A/B/E/F1-343[»]
1XNSX-ray2.80A/B20-343[»]
1XO0X-ray2.00A/B20-343[»]
2CRXX-ray2.50A/B1-343[»]
2HOFX-ray2.40A/B1-343[»]
2HOIX-ray2.60A/B/G/H1-343[»]
3C28X-ray2.60A/B20-341[»]
3C29X-ray2.20A/B/G/H20-341[»]
3CRXX-ray2.50A/B1-343[»]
3MGVX-ray2.29A/B/C/D1-343[»]
4CRXX-ray2.20A/B20-341[»]
5CRXX-ray2.70A/B1-343[»]
ProteinModelPortaliP06956
SMRiP06956
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2777477
KEGGivg:2777477

Miscellaneous databases

EvolutionaryTraceiP06956

Family and domain databases

Gene3Di1.10.150.130, 1 hit
1.10.443.10, 1 hit
InterProiView protein in InterPro
IPR011010 DNA_brk_join_enz
IPR013762 Integrase-like_cat_sf
IPR002104 Integrase_catalytic
IPR010998 Integrase_recombinase_N
PfamiView protein in Pfam
PF00589 Phage_integrase, 1 hit
SUPFAMiSSF56349 SSF56349, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRECR_BPP1
AccessioniPrimary (citable) accession number: P06956
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: January 1, 1988
Last modified: February 28, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again