RHO2

Protein namesⁱ	Recommended name: GTP-binding protein RHO2
Gene namesⁱ	Name:RHO2 Ordered Locus Names:YNL090W ORF Names:N2237
Organismⁱ	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifierⁱ	559292 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae
Proteomesⁱ	UP000002311 Componentⁱ: Chromosome XIV

Organism-specific databases

EuPathDBⁱ	FungiDB:YNL090W
Saccharomyces Genome Database More...SGDⁱ	S000005034 RHO2

Keywords - Cellular componentⁱ

Cell membrane, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000198946	1 – 189	GTP-binding protein RHO2Add BLAST		189
PropeptideⁱPRO_0000281276	190 – 192	Removed in mature formBy similarity		3

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Lipidationⁱ	188	S-palmitoyl cysteine1 Publication	1
Modified residueⁱ	189	Cysteine methyl esterBy similarity	1
Lipidationⁱ	189	S-geranylgeranyl cysteineBy similarity	1

Keywords - PTMⁱ

Lipoprotein, Methylation, Palmitate, Prenylation

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P06781
PaxDbⁱ	P06781
PRIDEⁱ	P06781

PTM databases

SwissPalmⁱ	P06781

SwissPalmⁱ

P06781

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	35734, 158 interactors
Database of interacting proteins More...DIPⁱ	DIP-5750N
IntActⁱ	P06781, 14 interactors
STRINGⁱ	4932.YNL090W

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P06781
SMRⁱ	P06781
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	36 – 44	Effector regionBy similarity		9

Sequence similaritiesⁱ

Belongs to the small GTPase superfamily. Rho family.Curated

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000149167
HOGENOMⁱ	HOG000233974
InParanoidⁱ	P06781
KEGG Orthology (KO) More...KOⁱ	K07975
OMAⁱ	DNVKHKW
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C4TDG

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR001806 Small_GTPase IPR003578 Small_GTPase_Rho
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00071 Ras, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS51420 RHO, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P06781-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSEKAVRRKL VIIGDGACGK TSLLYVFTLG KFPEQYHPTV FENYVTDCRV 
        60         70         80         90        100
DGIKVSLTLW DTAGQEEYER LRPFSYSKAD IILIGFAVDN FESLINARTK 
       110        120        130        140        150
WADEALRYCP DAPIVLVGLK KDLRQEAHFK ENATDEMVPI EDAKQVARAI 
       160        170        180        190 
GAKKYMECSA LTGEGVDDVF EVATRTSLLM KKEPGANCCI IL

Length:192

Mass (Da):21,479

Last modified:February 1, 1996 - v2

Checksum:ⁱ468AA876DF13F69C

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	48	C → S in AAA34978 (PubMed:3543936).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M15190 Genomic DNA Translation: AAA34978.1 AF458969 Genomic DNA Translation: AAM00517.1 AF458970 Genomic DNA Translation: AAM00523.1 AF458971 Genomic DNA Translation: AAM00529.1 AF458972 Genomic DNA Translation: AAM00535.1 AF458973 Genomic DNA Translation: AAM00541.1 AF458974 Genomic DNA Translation: AAM00547.1 AF458976 Genomic DNA Translation: AAM00559.1 AF458978 Genomic DNA Translation: AAM00571.1 AF458981 Genomic DNA Translation: AAM00589.1 DQ115393 Genomic DNA Translation: AAZ22518.1 X89016 Genomic DNA Translation: CAA61421.1 Z71366 Genomic DNA Translation: CAA95965.1 BK006947 Genomic DNA Translation: DAA10456.1
PIRⁱ	S57533 TVBYH2
NCBI Reference Sequences More...RefSeqⁱ	NP_014309.3, NM_001182928.3

Genome annotation databases

EnsemblFungiⁱ	YNL090W; YNL090W; YNL090W
GeneIDⁱ	855634
KEGGⁱ	sce:YNL090W

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P06781	Rho2p		YEASB		192	UniRef100_P06781
Protein RHO2		YEAS1		192
K7_Rho2p		YEASK		192
RHO2p small GTPase of the Rho/Rac family of Ras-like protein		Saccharomyces sp. 'boulardii'		192
Rho2p		YEASO		192
+2

Protein	Similar proteins		Species	Score	Length	Source
P06781	Rho2p		YEASB		192	UniRef90_P06781
Protein RHO2		YEAS1		192
K7_Rho2p		YEASK		192
RHO2p small GTPase of the Rho/Rac family of Ras-like protein		Saccharomyces sp. 'boulardii'		192
Rho2p		YEASO		192
+15

Protein	Similar proteins		Species	Score	Length	Source
P06781	Rho2p		YEASB		192	UniRef50_P06781
Protein RHO2		YEAS1		192
K7_Rho2p		YEASK		192
RHO2p small GTPase of the Rho/Rac family of Ras-like protein		Saccharomyces sp. 'boulardii'		192
Rho2p		YEASO		192
+31

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M15190 Genomic DNA Translation: AAA34978.1 AF458969 Genomic DNA Translation: AAM00517.1 AF458970 Genomic DNA Translation: AAM00523.1 AF458971 Genomic DNA Translation: AAM00529.1 AF458972 Genomic DNA Translation: AAM00535.1 AF458973 Genomic DNA Translation: AAM00541.1 AF458974 Genomic DNA Translation: AAM00547.1 AF458976 Genomic DNA Translation: AAM00559.1 AF458978 Genomic DNA Translation: AAM00571.1 AF458981 Genomic DNA Translation: AAM00589.1 DQ115393 Genomic DNA Translation: AAZ22518.1 X89016 Genomic DNA Translation: CAA61421.1 Z71366 Genomic DNA Translation: CAA95965.1 BK006947 Genomic DNA Translation: DAA10456.1
PIRⁱ	S57533 TVBYH2
RefSeqⁱ	NP_014309.3, NM_001182928.3

3D structure databases

ProteinModelPortalⁱ	P06781
SMRⁱ	P06781
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	35734, 158 interactors
DIPⁱ	DIP-5750N
IntActⁱ	P06781, 14 interactors
STRINGⁱ	4932.YNL090W

PTM databases

SwissPalmⁱ	P06781

SwissPalmⁱ

P06781

Proteomic databases

MaxQBⁱ	P06781
PaxDbⁱ	P06781
PRIDEⁱ	P06781

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	YNL090W; YNL090W; YNL090W
GeneIDⁱ	855634
KEGGⁱ	sce:YNL090W

Organism-specific databases

EuPathDBⁱ	FungiDB:YNL090W
SGDⁱ	S000005034 RHO2

Phylogenomic databases

GeneTreeⁱ	ENSGT00920000149167
HOGENOMⁱ	HOG000233974
InParanoidⁱ	P06781
KOⁱ	K07975
OMAⁱ	DNVKHKW
OrthoDBⁱ	EOG092C4TDG

Enzyme and pathway databases

BioCycⁱ	YEAST:G3O-33118-MONOMER
Reactomeⁱ	R-SCE-194840 Rho GTPase cycle

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P06781

PROⁱ

PR:P06781

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR005225 Small_GTP-bd_dom IPR001806 Small_GTPase IPR003578 Small_GTPase_Rho
Pfamⁱ	View protein in Pfam PF00071 Ras, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 1 hit
TIGRFAMsⁱ	TIGR00231 small_GTP, 1 hit
PROSITEⁱ	View protein in PROSITE PS51420 RHO, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RHO2_YEAST
Accessionⁱ	P06781Primary (citable) accession number: P06781 Secondary accession number(s): D6W190, Q45TZ2
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 1, 1988
	Last sequence update:	February 1, 1996
	Last modified:	September 12, 2018
	This is version 178 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P06781 (RHO2_YEAST)

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GTP-binding protein RHO2

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ