UniProtKB - P06535 (SP0B_BACSU)
Protein
Sporulation initiation phosphotransferase B
Gene
spo0B
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Key element in the phosphorelay regulating sporulation initiation. Acts on spo0A. Mediates reversible phosphoryl transfer from spo0F to spo0A.
GO - Molecular functioni
- phosphorelay sensor kinase activity Source: InterPro
GO - Biological processi
- sporulation resulting in formation of a cellular spore Source: UniProtKB-KW
Keywordsi
Molecular function | Kinase, Transferase |
Biological process | Sensory transduction, Sporulation |
Enzyme and pathway databases
BioCyci | BSUB:BSU27930-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Sporulation initiation phosphotransferase B (EC:2.7.-.-)Alternative name(s): Stage 0 sporulation protein B Stage 0 sporulation protein D |
Gene namesi | Name:spo0B Synonyms:spo0D Ordered Locus Names:BSU27930 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Subcellular locationi
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 30 | H → A: Loss of sporulation. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000072052 | 1 – 192 | Sporulation initiation phosphotransferase BAdd BLAST | 192 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 30 | Phosphohistidine1 Publication | 1 |
Post-translational modificationi
Phosphorylated by spo0F.1 Publication
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | P06535 |
PRIDEi | P06535 |
PTM databases
iPTMneti | P06535 |
Expressioni
Developmental stagei
Expressed during sporulation.
Interactioni
Subunit structurei
Homodimer. Dimerization is essential for activity as both monomers contribute to the formation of the active site.
Protein-protein interaction databases
STRINGi | 224308.BSU27930 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P06535 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P06535 |
Family & Domainsi
Phylogenomic databases
HOGENOMi | HOG000097276 |
KOi | K06375 |
OMAi | RHARHDW |
Family and domain databases
Gene3Di | 3.30.565.30, 1 hit |
InterProi | View protein in InterPro IPR016120 Sig_transdc_His_kin_SpoOB IPR037100 Spo0B_C_sf IPR039506 SPOB_a IPR016122 SpoOB_C |
Pfami | View protein in Pfam PF14689 SPOB_a, 1 hit PF14682 SPOB_ab, 1 hit |
SMARTi | View protein in SMART SM01317 SPOB_ab, 1 hit |
SUPFAMi | SSF55890 SSF55890, 1 hit |
i Sequence
Sequence statusi: Complete.
P06535-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKDVSKNQEE NISDTALTNE LIHLLGHSRH DWMNKLQLIK GNLSLQKYDR
60 70 80 90 100
VFEMIEEMVI DAKHESKLSN LKTPHLAFDF LTFNWKTHYM TLEYEVLGEI
110 120 130 140 150
KDLSAYDQKL AKLMRKLFHL FDQAVSRESE NHLTVSLQTD HPDRQLILYL
160 170 180 190
DFHGAFADPS AFDDIRQNGY EDVDIMRFEI TSHECLIEIG LD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X02655 Genomic DNA Translation: CAA26489.1 M24537 Genomic DNA Translation: AAA22504.1 K02664 Genomic DNA Translation: AAB05348.1 AL009126 Genomic DNA Translation: CAB14753.1 |
PIRi | A22974 SZBS0B |
RefSeqi | NP_390671.1, NC_000964.3 WP_004399131.1, NZ_JNCM01000036.1 |
Genome annotation databases
EnsemblBacteriai | CAB14753; CAB14753; BSU27930 |
GeneIDi | 935956 |
KEGGi | bsu:BSU27930 |
PATRICi | fig|224308.179.peg.3034 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X02655 Genomic DNA Translation: CAA26489.1 M24537 Genomic DNA Translation: AAA22504.1 K02664 Genomic DNA Translation: AAB05348.1 AL009126 Genomic DNA Translation: CAB14753.1 |
PIRi | A22974 SZBS0B |
RefSeqi | NP_390671.1, NC_000964.3 WP_004399131.1, NZ_JNCM01000036.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1F51 | X-ray | 3.00 | A/B/C/D | 11-192 | [»] | |
1IXM | X-ray | 2.60 | A/B | 1-192 | [»] | |
2FTK | X-ray | 3.05 | A/B/C/D | 1-192 | [»] | |
SMRi | P06535 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU27930 |
PTM databases
iPTMneti | P06535 |
Proteomic databases
PaxDbi | P06535 |
PRIDEi | P06535 |
Genome annotation databases
EnsemblBacteriai | CAB14753; CAB14753; BSU27930 |
GeneIDi | 935956 |
KEGGi | bsu:BSU27930 |
PATRICi | fig|224308.179.peg.3034 |
Phylogenomic databases
HOGENOMi | HOG000097276 |
KOi | K06375 |
OMAi | RHARHDW |
Enzyme and pathway databases
BioCyci | BSUB:BSU27930-MONOMER |
Miscellaneous databases
EvolutionaryTracei | P06535 |
Family and domain databases
Gene3Di | 3.30.565.30, 1 hit |
InterProi | View protein in InterPro IPR016120 Sig_transdc_His_kin_SpoOB IPR037100 Spo0B_C_sf IPR039506 SPOB_a IPR016122 SpoOB_C |
Pfami | View protein in Pfam PF14689 SPOB_a, 1 hit PF14682 SPOB_ab, 1 hit |
SMARTi | View protein in SMART SM01317 SPOB_ab, 1 hit |
SUPFAMi | SSF55890 SSF55890, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SP0B_BACSU | |
Accessioni | P06535Primary (citable) accession number: P06535 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 1, 1988 |
Last sequence update: | January 1, 1988 | |
Last modified: | September 18, 2019 | |
This is version 132 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Complete proteome, Reference proteomeDocuments
- Bacillus subtilis
Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList - PDB cross-references
Index of Protein Data Bank (PDB) cross-references