UniProtKB - P06281 (RENI1_MOUSE)

BLAST

>sp|P06281|RENI1_MOUSE Renin-1 OS=Mus musculus OX=10090 GN=Ren1 PE=1 SV=1
MDRRRMPLWALLLLWSPCTFSLPTRTATFERIPLKKMPSVREILEERGVDMTRLSAEWGV
FTKRPSLTNLTSPVVLTNYLNTQYYGEIGIGTPPQTFKVIFDTGSANLWVPSTKCSRLYL
ACGIHSLYESSDSSSYMENGSDFTIHYGSGRVKGFLSQDSVTVGGITVTQTFGEVTELPL
IPFMLAKFDGVLGMGFPAQAVGGVTPVFDHILSQGVLKEEVFSVYYNRGSHLLGGEVVLG
GSDPQHYQGNFHYVSISKTDSWQITMKGVSVGSSTLLCEEGCAVVVDTGSSFISAPTSSL
KLIMQALGAKEKRIEEYVVNCSQVPTLPDISFDLGGRAYTLSSTDYVLQYPNRRDKLCTL
ALHAMDIPPPTGPVWVLGATFIRKFYTEFDRHNNRIGFALAR

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History
Entry version 175 (12 Sep 2018)
Sequence version 1 (01 Jan 1988)
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Protein

Renin-1

Gene

Ren1

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

Catalytic activityⁱ

Cleavage of Leu-|-Xaa bond in angiotensinogen to generate angiotensin I.

Activity regulationⁱ

Interaction with ATP6AP2 results in a 5-fold increased efficiency in angiotensinogen processing.By similarity

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	102	PROSITE-ProRule annotation		1
Active siteⁱ	287	PROSITE-ProRule annotation		1

GO - Molecular functionⁱ

aspartic-type endopeptidase activity Source: MGI
endopeptidase activity
Source: MGI
Inferred from direct assayⁱ
- 19293336
insulin-like growth factor receptor binding Source: MGI
peptidase activity Source: MGI
signaling receptor binding Source: MGI

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

amyloid-beta metabolic process Source: Ensembl
angiotensin maturation
Source: MGI
Inferred from mutant phenotypeⁱ
- 10617578
cell maturation
Source: MGI
Inferred from mutant phenotypeⁱ
- 10617578
cellular response to drug Source: Ensembl
drinking behavior
Source: MGI
Inferred from mutant phenotypeⁱ
- 10617578
hormone-mediated signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 14583438
kidney development Source: MGI
male gonad development
Source: UniProtKB
Inferred from expression patternⁱ
- 11145610
mesonephros development
Source: UniProtKB
Inferred from expression patternⁱ
- 11145610
proteolysis Source: MGI
regulation of blood pressure Source: MGI
regulation of blood volume by renin-angiotensin
Source: MGI
Inferred from mutant phenotypeⁱ
- 10617578
regulation of MAPK cascade Source: MGI
renin-angiotensin regulation of aldosterone production
Source: MGI
Inferred from direct assayⁱ
- 19293336
response to cAMP Source: MGI
response to cGMP Source: MGI
response to drug Source: MGI
response to immobilization stress Source: Ensembl
response to lipopolysaccharide Source: Ensembl
response to organic substance
Source: MGI
Inferred from direct assayⁱ
- 19293336

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Aspartyl protease, Hydrolase, Protease

Molecular function

Aspartyl protease, Hydrolase, Protease

Enzyme and pathway databases

Reactomeⁱ	R-MMU-2022377 Metabolism of Angiotensinogen to Angiotensins

Reactomeⁱ

R-MMU-2022377 Metabolism of Angiotensinogen to Angiotensins

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Renin-1 (EC:3.4.23.15) Alternative name(s): Angiotensinogenase Kidney renin
Gene namesⁱ	Name:Ren1 Synonyms:Ren, Ren-1
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 1

Organism-specific databases

MGIⁱ	MGI:97898 Ren1

Keywords - Cellular componentⁱ

Membrane, Secreted

Pathology & Biotechⁱ

Chemistry databases

ChEMBLⁱ	CHEMBL2615

ChEMBLⁱ

CHEMBL2615

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Length
Signal peptideⁱ	1 – 21	1 PublicationAdd BLAST	21
PropeptideⁱPRO_0000026089	22 – 71	Activation peptide1 PublicationAdd BLAST	50
ChainⁱPRO_0000026090	72 – 402	Renin-1Add BLAST	331

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	69	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	115 ↔ 122	By similarity
Glycosylationⁱ	139	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	278 ↔ 282	By similarity
Glycosylationⁱ	320	N-linked (GlcNAc...) asparagineSequence analysis	1

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P06281
PaxDbⁱ	P06281
PeptideAtlas More...PeptideAtlasⁱ	P06281
PRIDEⁱ	P06281

PTM databases

PhosphoSitePlusⁱ	P06281

PhosphoSitePlusⁱ

P06281

Expressionⁱ

Tissue specificityⁱ

Kidney.

Inductionⁱ

Renal renin is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration.

Gene expression databases

Bgeeⁱ	ENSMUSG00000070645 Expressed in 82 organ(s), highest expression level in submandibular gland
CleanExⁱ	MM_REN1
ExpressionAtlasⁱ	P06281 baseline and differential
Genevisibleⁱ	P06281 MM

Interactionⁱ

Subunit structureⁱ

Interacts with ATP6AP2.By similarity

GO - Molecular functionⁱ

insulin-like growth factor receptor binding Source: MGI
signaling receptor binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

IntActⁱ	P06281, 1 interactor
Molecular INTeraction database More...MINTⁱ	P06281
STRINGⁱ	10090.ENSMUSP00000092135

Chemistry databases

BindingDBⁱ

P06281

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	40 – 47	Combined sources	8
Beta strandⁱ	84 – 90	Combined sources	7
Turnⁱ	91 – 94	Combined sources	4
Beta strandⁱ	95 – 104	Combined sources	10
Beta strandⁱ	108 – 112	Combined sources	5
Helixⁱ	120 – 123	Combined sources	4
Helixⁱ	130 – 132	Combined sources	3
Beta strandⁱ	137 – 145	Combined sources	9
Beta strandⁱ	148 – 150	Combined sources	3
Beta strandⁱ	152 – 163	Combined sources	12
Beta strandⁱ	166 – 177	Combined sources	12
Helixⁱ	180 – 183	Combined sources	4
Beta strandⁱ	190 – 193	Combined sources	4
Helixⁱ	207 – 214	Combined sources	8
Beta strandⁱ	217 – 226	Combined sources	10
Beta strandⁱ	235 – 241	Combined sources	7
Helixⁱ	244 – 246	Combined sources	3
Beta strandⁱ	248 – 255	Combined sources	8
Beta strandⁱ	258 – 266	Combined sources	9
Beta strandⁱ	269 – 271	Combined sources	3
Beta strandⁱ	274 – 277	Combined sources	4
Beta strandⁱ	282 – 285	Combined sources	4
Beta strandⁱ	292 – 294	Combined sources	3
Helixⁱ	297 – 305	Combined sources	9
Beta strandⁱ	330 – 334	Combined sources	5
Beta strandⁱ	337 – 341	Combined sources	5
Beta strandⁱ	369 – 371	Combined sources	3
Beta strandⁱ	373 – 376	Combined sources	4
Helixⁱ	379 – 384	Combined sources	6
Beta strandⁱ	385 – 390	Combined sources	6
Turnⁱ	391 – 394	Combined sources	4
Beta strandⁱ	395 – 400	Combined sources	6

Show more details

3D structure databases

ProteinModelPortalⁱ	P06281
SMRⁱ	P06281
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	84 – 399	Peptidase A1PROSITE-ProRule annotationAdd BLAST		316

Sequence similaritiesⁱ

Belongs to the peptidase A1 family.Curated

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	KOG1339 Eukaryota ENOG410XNV7 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118929
HOGENOMⁱ	HOG000197681
HOVERGENⁱ	HBG000482
InParanoidⁱ	P06281
KEGG Orthology (KO) More...KOⁱ	K01380
OMAⁱ	LGKYYTE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0JP7
PhylomeDBⁱ	P06281
TreeFamⁱ	TF314990

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd05487 renin_like, 1 hit
Gene3Dⁱ	2.40.70.10, 2 hits
InterProⁱ	View protein in InterPro IPR001461 Aspartic_peptidase_A1 IPR001969 Aspartic_peptidase_AS IPR012848 Aspartic_peptidase_N IPR033121 PEPTIDASE_A1 IPR021109 Peptidase_aspartic_dom_sf IPR034135 Renin-like_dom
PANTHERⁱ	PTHR13683 PTHR13683, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07966 A1_Propeptide, 1 hit PF00026 Asp, 1 hit
PRINTSⁱ	PR00792 PEPSIN
SUPFAMⁱ	SSF50630 SSF50630, 1 hit
PROSITEⁱ	View protein in PROSITE PS00141 ASP_PROTEASE, 2 hits PS51767 PEPTIDASE_A1, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

P06281-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDRRRMPLWA LLLLWSPCTF SLPTRTATFE RIPLKKMPSV REILEERGVD 
        60         70         80         90        100
MTRLSAEWGV FTKRPSLTNL TSPVVLTNYL NTQYYGEIGI GTPPQTFKVI 
       110        120        130        140        150
FDTGSANLWV PSTKCSRLYL ACGIHSLYES SDSSSYMENG SDFTIHYGSG 
       160        170        180        190        200
RVKGFLSQDS VTVGGITVTQ TFGEVTELPL IPFMLAKFDG VLGMGFPAQA 
       210        220        230        240        250
VGGVTPVFDH ILSQGVLKEE VFSVYYNRGS HLLGGEVVLG GSDPQHYQGN 
       260        270        280        290        300
FHYVSISKTD SWQITMKGVS VGSSTLLCEE GCAVVVDTGS SFISAPTSSL 
       310        320        330        340        350
KLIMQALGAK EKRIEEYVVN CSQVPTLPDI SFDLGGRAYT LSSTDYVLQY 
       360        370        380        390        400
PNRRDKLCTL ALHAMDIPPP TGPVWVLGAT FIRKFYTEFD RHNNRIGFAL 

AR

Length:402

Mass (Da):44,343

Last modified:January 1, 1988 - v1

Checksum:ⁱD42920B555E97A38

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	Q9R259	Q9R259_MOUSE		Renin b Renin b (Renin-1)	Ren1	44	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	6 – 23	Missing (PubMed:6370686).CuratedAdd BLAST	18
Sequence conflictⁱ	24	T → I (PubMed:6370686).Curated	1
Sequence conflictⁱ	163	V → VSRV (PubMed:6370686).Curated	1

Polymorphismⁱ

In inbred mouse strains, there are at least two alleles which can occur at the Ren1 locus: Ren-1D and Ren-1C. The sequence shown is that of Ren-1C.

Present as a single-copy gene in strains such as BALB/c and C57BL/6 while some strains such as Swiss and Akr contain two copies.

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱ	58	W → R in allele Ren-1D. 1 Publication	1
Natural variantⁱ	68	T → I in allele Ren-1D. 1 Publication	1
Natural variantⁱ	160	S → V in allele Ren-1D; requires 2 nucleotide substitutions. 1 Publication	1
Natural variantⁱ	315	E → D in allele Ren-1D. 2 Publications	1
Natural variantⁱ	352	N → Y in allele Ren-1D. Combined sources1 Publication	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X00810 X00851 Genomic DNA Translation: CAA25391.1 X16642 mRNA Translation: CAA34636.1 K02596 Genomic DNA Translation: AAA40045.1 M32352 Genomic DNA Translation: AAA40043.1 AK052685 mRNA Translation: BAC35094.1 AK085309 mRNA Translation: BAC39418.1 BC061053 mRNA Translation: AAH61053.1 K02800 Genomic DNA Translation: AAA40044.1 M34190 Genomic DNA Translation: AAA40042.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS15295.1
PIRⁱ	A00989 REMSK
NCBI Reference Sequences More...RefSeqⁱ	NP_112469.1, NM_031192.3
UniGeneⁱ	Mm.220955

Genome annotation databases

Ensemblⁱ	ENSMUST00000094556; ENSMUSP00000092135; ENSMUSG00000070645
GeneIDⁱ	19701
KEGGⁱ	mmu:19701
UCSC genome browser More...UCSCⁱ	uc007cqf.1 mouse

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P06281	Renin b (Fragment)		MOUSE		44	UniRef100_P06281

Protein	Similar proteins		Species	Score	Length	Source
P06281	Renin-2	)	MOUSE		401	UniRef90_P06281
UPI000A318429		MUSCR		402
UPI000A30B916		MUSPA		402
Renin b (Fragment)		MOUSE		44
Ren2 protein		MOUSE		401
+2

Protein	Similar proteins		Species	Score	Length	Source
P06281	Renin	)	HUMAN		406	UniRef50_P00797
Renin		PANTR		406
Renin		MACMU		406
Renin		MACFA		406
Renin		CALJA		400
+227

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X00810 X00851 Genomic DNA Translation: CAA25391.1 X16642 mRNA Translation: CAA34636.1 K02596 Genomic DNA Translation: AAA40045.1 M32352 Genomic DNA Translation: AAA40043.1 AK052685 mRNA Translation: BAC35094.1 AK085309 mRNA Translation: BAC39418.1 BC061053 mRNA Translation: AAH61053.1 K02800 Genomic DNA Translation: AAA40044.1 M34190 Genomic DNA Translation: AAA40042.1
CCDSⁱ	CCDS15295.1
PIRⁱ	A00989 REMSK
RefSeqⁱ	NP_112469.1, NM_031192.3
UniGeneⁱ	Mm.220955

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	5MKT	X-ray	3.20	A	22-402	[»]
ProteinModelPortalⁱ	P06281
SMRⁱ	P06281
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	P06281, 1 interactor
MINTⁱ	P06281
STRINGⁱ	10090.ENSMUSP00000092135

Chemistry databases

BindingDBⁱ	P06281
ChEMBLⁱ	CHEMBL2615

PTM databases

PhosphoSitePlusⁱ	P06281

PhosphoSitePlusⁱ

P06281

Proteomic databases

MaxQBⁱ	P06281
PaxDbⁱ	P06281
PeptideAtlasⁱ	P06281
PRIDEⁱ	P06281

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000094556; ENSMUSP00000092135; ENSMUSG00000070645
GeneIDⁱ	19701
KEGGⁱ	mmu:19701
UCSCⁱ	uc007cqf.1 mouse

Organism-specific databases

CTDⁱ	19701
MGIⁱ	MGI:97898 Ren1

Phylogenomic databases

eggNOGⁱ	KOG1339 Eukaryota ENOG410XNV7 LUCA
GeneTreeⁱ	ENSGT00760000118929
HOGENOMⁱ	HOG000197681
HOVERGENⁱ	HBG000482
InParanoidⁱ	P06281
KOⁱ	K01380
OMAⁱ	LGKYYTE
OrthoDBⁱ	EOG091G0JP7
PhylomeDBⁱ	P06281
TreeFamⁱ	TF314990

Enzyme and pathway databases

Reactomeⁱ	R-MMU-2022377 Metabolism of Angiotensinogen to Angiotensins

Reactomeⁱ

R-MMU-2022377 Metabolism of Angiotensinogen to Angiotensins

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P06281
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000070645 Expressed in 82 organ(s), highest expression level in submandibular gland
CleanExⁱ	MM_REN1
ExpressionAtlasⁱ	P06281 baseline and differential
Genevisibleⁱ	P06281 MM

Family and domain databases

CDDⁱ	cd05487 renin_like, 1 hit
Gene3Dⁱ	2.40.70.10, 2 hits
InterProⁱ	View protein in InterPro IPR001461 Aspartic_peptidase_A1 IPR001969 Aspartic_peptidase_AS IPR012848 Aspartic_peptidase_N IPR033121 PEPTIDASE_A1 IPR021109 Peptidase_aspartic_dom_sf IPR034135 Renin-like_dom
PANTHERⁱ	PTHR13683 PTHR13683, 1 hit
Pfamⁱ	View protein in Pfam PF07966 A1_Propeptide, 1 hit PF00026 Asp, 1 hit
PRINTSⁱ	PR00792 PEPSIN
SUPFAMⁱ	SSF50630 SSF50630, 1 hit
PROSITEⁱ	View protein in PROSITE PS00141 ASP_PROTEASE, 2 hits PS51767 PEPTIDASE_A1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RENI1_MOUSE
Accessionⁱ	P06281Primary (citable) accession number: P06281 Secondary accession number(s): P97911 , Q543E5, Q62153, Q62154
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 1, 1988
	Last sequence update:	January 1, 1988
	Last modified:	September 12, 2018
	This is version 175 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Peptidase families
Classification of peptidase families and list of entries
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

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Supporting data

UniProtKB - P06281 (RENI1_MOUSE)

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Renin-1

Ren1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Other locations

Extracellular region or secreted

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ