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Protein

Quinone-dependent D-lactate dehydrogenase

Gene

dld

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the oxidation of D-lactate to pyruvate. Electrons derived from D-lactate oxidation are transferred to the ubiquinone/cytochrome electron transfer chain, where they may be used to provide energy for the active transport of a variety of amino acids and sugars across the membrane.5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

FADUniRule annotation4 Publications

<p>This subsection of the ‘Function’ section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by 2-hydroxy-3-butynoic acid, but not by p-chloromercuribenzoate, n-ethylmaleimide, or 5,5'-dithiobis(2-nitrobenzoic acid).1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.16 mM for D-lactate1 Publication

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Function’ section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei143FAD; via amide nitrogenUniRule annotationCombined sources1 Publication1
    Binding sitei150FADUniRule annotationCombined sources1 Publication1
    Binding sitei160FAD; via amide nitrogenUniRule annotationCombined sources1 Publication1
    Binding sitei262FAD; via amide nitrogen and carbonyl oxygenUniRule annotationCombined sources1 Publication1

    Regions

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi76 – 80FADUniRule annotationCombined sources1 Publication5
    Nucleotide bindingi84 – 85FADUniRule annotationCombined sources1 Publication2

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    LigandFAD, Flavoprotein

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    EcoCyc:DLACTDEHYDROGFAD-MONOMER
    MetaCyc:DLACTDEHYDROGFAD-MONOMER

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    1.1.1.28 2026

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Quinone-dependent D-lactate dehydrogenaseUniRule annotationCurated (EC:1.1.5.12UniRule annotation2 Publications)
    Alternative name(s):
    (R)-lactate:quinone 2-oxidoreductaseCurated
    D-lactate dehydrogenase2 PublicationsUniRule annotation
    Short name:
    D-LDH1 PublicationUniRule annotation
    Respiratory D-lactate dehydrogenaseCurated
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:dld1 PublicationUniRule annotation
    Ordered Locus Names:b2133, JW2121
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
    • UP000000625 Componenti: Chromosome

    Organism-specific databases

    Escherichia coli strain K12 genome database

    More...
    EcoGenei
    EG10231 dld

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    • Cell inner membrane UniRule annotation3 Publications; Peripheral membrane protein UniRule annotation1 Publication; Cytoplasmic side UniRule annotation1 Publication
    • Note: May bind the membrane through electrostatic rather than hydrophobic forces.1 Publication

    GO - Cellular componenti

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Chemistry databases

    Drug and drug target database

    More...
    DrugBanki
    DB03147 Flavin adenine dinucleotide
    DB00756 Hexachlorophene

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000799282 – 571Quinone-dependent D-lactate dehydrogenaseAdd BLAST570

    Keywords - PTMi

    Quinone

    Proteomic databases

    Encyclopedia of Proteome Dynamics

    More...
    EPDi
    P06149

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    P06149

    PRoteomics IDEntifications database

    More...
    PRIDEi
    P06149

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    The Biological General Repository for Interaction Datasets (BioGrid)

    More...
    BioGridi
    4260452, 20 interactors

    Protein interaction database and analysis system

    More...
    IntActi
    P06149, 17 interactors

    STRING: functional protein association networks

    More...
    STRINGi
    316385.ECDH10B_2289

    Chemistry databases

    BindingDB database of measured binding affinities

    More...
    BindingDBi
    P06149

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    1571
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

    More...
    ProteinModelPortali
    P06149

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    P06149

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    Miscellaneous databases

    Relative evolutionary importance of amino acids within a protein sequence

    More...
    EvolutionaryTracei
    P06149

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 213FAD-binding PCMH-typeUniRule annotationAdd BLAST172

    <p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

    Contains 3 domains: the flavin adenine dinucleotide (FAD)-binding domain, the cap domain and the membrane-binding domain.1 Publication

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the quinone-dependent D-lactate dehydrogenase family.UniRule annotationCurated

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    ENOG4105CXG Bacteria
    COG0277 LUCA

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    HOG000122232

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    P06149

    KEGG Orthology (KO)

    More...
    KOi
    K03777

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    3.30.1370.20, 1 hit
    3.30.43.10, 1 hit
    3.30.465.10, 1 hit
    3.30.70.610, 2 hits

    HAMAP database of protein families

    More...
    HAMAPi
    MF_02092 DLDH_Dld, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR016172 D-lactate_DH_C-sub1
    IPR016173 D-lactate_DH_C-sub2
    IPR012256 D_lactate_DH
    IPR016166 FAD-bd_PCMH
    IPR036318 FAD-bd_PCMH-like_sf
    IPR016167 FAD-bd_PCMH_sub1
    IPR016169 FAD-bd_PCMH_sub2
    IPR016164 FAD-linked_Oxase-like_C
    IPR015409 Lactate_DH_C
    IPR006094 Oxid_FAD_bind_N

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF01565 FAD_binding_4, 1 hit
    PF09330 Lact-deh-memb, 1 hit

    PIRSF; a whole-protein classification database

    More...
    PIRSFi
    PIRSF000101 D-lactate_dh, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF55103 SSF55103, 1 hit
    SSF56176 SSF56176, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS51387 FAD_PCMH, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    P06149-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MSSMTTTDNK AFLNELARLV GSSHLLTDPA KTARYRKGFR SGQGDALAVV
    60 70 80 90 100
    FPGSLLELWR VLKACVTADK IILMQAANTG LTEGSTPNGN DYDRDVVIIS
    110 120 130 140 150
    TLRLDKLHVL GKGEQVLAYP GTTLYSLEKA LKPLGREPHS VIGSSCIGAS
    160 170 180 190 200
    VIGGICNNSG GSLVQRGPAY TEMSLFARIN EDGKLTLVNH LGIDLGETPE
    210 220 230 240 250
    QILSKLDDDR IKDDDVRHDG RHAHDYDYVH RVRDIEADTP ARYNADPDRL
    260 270 280 290 300
    FESSGCAGKL AVFAVRLDTF EAEKNQQVFY IGTNQPEVLT EIRRHILANF
    310 320 330 340 350
    ENLPVAGEYM HRDIYDIAEK YGKDTFLMID KLGTDKMPFF FNLKGRTDAM
    360 370 380 390 400
    LEKVKFFRPH FTDRAMQKFG HLFPSHLPPR MKNWRDKYEH HLLLKMAGDG
    410 420 430 440 450
    VGEAKSWLVD YFKQAEGDFF VCTPEEGSKA FLHRFAAAGA AIRYQAVHSD
    460 470 480 490 500
    EVEDILALDI ALRRNDTEWY EHLPPEIDSQ LVHKLYYGHF MCYVFHQDYI
    510 520 530 540 550
    VKKGVDVHAL KEQMLELLQQ RGAQYPAEHN VGHLYKAPET LQKFYRENDP
    560 570
    TNSMNPGIGK TSKRKNWQEV E
    Length:571
    Mass (Da):64,612
    Last modified:January 23, 2007 - v3
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i77FB2C467CB4389F
    GO

    <p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence AAA60530 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    M10038 Genomic DNA Translation: AAA23688.1
    X01067 Genomic DNA Translation: CAA25531.1
    U00007 Genomic DNA Translation: AAA60530.1 Different initiation.
    U00096 Genomic DNA Translation: AAC75194.1
    AP009048 Genomic DNA Translation: BAE76610.1

    Protein sequence database of the Protein Information Resource

    More...
    PIRi
    A21893 DEECDL

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_416637.1, NC_000913.3
    WP_000097403.1, NZ_LN832404.1

    Genome annotation databases

    Ensembl bacterial and archaeal genome annotation project

    More...
    EnsemblBacteriai
    AAC75194; AAC75194; b2133
    BAE76610; BAE76610; BAE76610

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    946653

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    ecj:JW2121
    eco:b2133

    Pathosystems Resource Integration Center (PATRIC)

    More...
    PATRICi
    fig|1411691.4.peg.110

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    M10038 Genomic DNA Translation: AAA23688.1
    X01067 Genomic DNA Translation: CAA25531.1
    U00007 Genomic DNA Translation: AAA60530.1 Different initiation.
    U00096 Genomic DNA Translation: AAC75194.1
    AP009048 Genomic DNA Translation: BAE76610.1
    PIRiA21893 DEECDL
    RefSeqiNP_416637.1, NC_000913.3
    WP_000097403.1, NZ_LN832404.1

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...
    PDBei

    Protein Data Bank RCSB

    More...
    RCSB PDBi

    Protein Data Bank Japan

    More...
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    1F0XX-ray1.90A/B1-571[»]
    ProteinModelPortaliP06149
    SMRiP06149
    ModBaseiSearch...
    MobiDBiSearch...

    Protein-protein interaction databases

    BioGridi4260452, 20 interactors
    IntActiP06149, 17 interactors
    STRINGi316385.ECDH10B_2289

    Chemistry databases

    BindingDBiP06149
    DrugBankiDB03147 Flavin adenine dinucleotide
    DB00756 Hexachlorophene

    Proteomic databases

    EPDiP06149
    PaxDbiP06149
    PRIDEiP06149

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Genome annotation databases

    EnsemblBacteriaiAAC75194; AAC75194; b2133
    BAE76610; BAE76610; BAE76610
    GeneIDi946653
    KEGGiecj:JW2121
    eco:b2133
    PATRICifig|1411691.4.peg.110

    Organism-specific databases

    EchoBASE - an integrated post-genomic database for E. coli

    More...
    EchoBASEi
    EB0227
    EcoGeneiEG10231 dld

    Phylogenomic databases

    eggNOGiENOG4105CXG Bacteria
    COG0277 LUCA
    HOGENOMiHOG000122232
    InParanoidiP06149
    KOiK03777

    Enzyme and pathway databases

    BioCyciEcoCyc:DLACTDEHYDROGFAD-MONOMER
    MetaCyc:DLACTDEHYDROGFAD-MONOMER
    BRENDAi1.1.1.28 2026

    Miscellaneous databases

    EvolutionaryTraceiP06149

    Protein Ontology

    More...
    PROi
    PR:P06149

    Family and domain databases

    Gene3Di3.30.1370.20, 1 hit
    3.30.43.10, 1 hit
    3.30.465.10, 1 hit
    3.30.70.610, 2 hits
    HAMAPiMF_02092 DLDH_Dld, 1 hit
    InterProiView protein in InterPro
    IPR016172 D-lactate_DH_C-sub1
    IPR016173 D-lactate_DH_C-sub2
    IPR012256 D_lactate_DH
    IPR016166 FAD-bd_PCMH
    IPR036318 FAD-bd_PCMH-like_sf
    IPR016167 FAD-bd_PCMH_sub1
    IPR016169 FAD-bd_PCMH_sub2
    IPR016164 FAD-linked_Oxase-like_C
    IPR015409 Lactate_DH_C
    IPR006094 Oxid_FAD_bind_N
    PfamiView protein in Pfam
    PF01565 FAD_binding_4, 1 hit
    PF09330 Lact-deh-memb, 1 hit
    PIRSFiPIRSF000101 D-lactate_dh, 1 hit
    SUPFAMiSSF55103 SSF55103, 1 hit
    SSF56176 SSF56176, 1 hit
    PROSITEiView protein in PROSITE
    PS51387 FAD_PCMH, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDLD_ECOLI
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P06149
    Secondary accession number(s): Q2MAU6
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
    Last sequence update: January 23, 2007
    Last modified: December 5, 2018
    This is version 163 of the entry and version 3 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families
    3. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
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