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Entry version 184 (13 Nov 2019)
Sequence version 2 (01 Oct 1993)
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Protein

Vitamin B12 transporter BtuB

Gene

btuB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB. Is also a receptor for bacteriophages BF23 and C1, and for A and E colicins.3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Calcium increases vitamin B12 binding affinity by a factor of 50-100.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi199Calcium 11 Publication1
Metal bindingi211Calcium 11 Publication1
Metal bindingi213Calcium 11 Publication1
Metal bindingi213Calcium 21 Publication1
Metal bindingi215Calcium 11 Publication1
Metal bindingi215Calcium 21 Publication1
Metal bindingi249Calcium 2; via carbonyl oxygen1 Publication1
Metal bindingi250Calcium 11 Publication1
Metal bindingi250Calcium 21 Publication1
Metal bindingi261Calcium 21 Publication1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionPorin, Receptor
Biological processIon transport, Transport
LigandCalcium, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:EG10126-MONOMER
ECOL316407:JW3938-MONOMER
MetaCyc:EG10126-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.B.14.3.1 the outer membrane receptor (omr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Vitamin B12 transporter BtuBUniRule annotation
Alternative name(s):
Cobalamin receptorUniRule annotation
Outer membrane cobalamin translocatorUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:btuB
Synonyms:bfe, cer, dcrC
Ordered Locus Names:b3966, JW3938
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini21 – 157Periplasmic1 PublicationAdd BLAST137
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei158 – 165Beta stranded8
Topological domaini166 – 168Extracellular1 Publication3
Transmembranei169 – 178Beta stranded10
Topological domaini179 – 183Periplasmic1 Publication5
Transmembranei184 – 195Beta strandedAdd BLAST12
Topological domaini196 – 216Extracellular1 PublicationAdd BLAST21
Transmembranei217 – 227Beta strandedAdd BLAST11
Topological domaini228 – 231Periplasmic1 Publication4
Transmembranei232 – 248Beta strandedAdd BLAST17
Topological domaini249 – 262Extracellular1 PublicationAdd BLAST14
Transmembranei263 – 277Beta strandedAdd BLAST15
Topological domaini278Periplasmic1 Publication1
Transmembranei279 – 296Beta strandedAdd BLAST18
Topological domaini297 – 308Extracellular1 PublicationAdd BLAST12
Transmembranei309 – 325Beta strandedAdd BLAST17
Topological domaini326 – 327Periplasmic1 Publication2
Transmembranei328 – 337Beta stranded10
Topological domaini338 – 352Extracellular1 PublicationAdd BLAST15
Transmembranei353 – 369Beta strandedAdd BLAST17
Topological domaini370Periplasmic1 Publication1
Transmembranei371 – 381Beta strandedAdd BLAST11
Topological domaini382 – 384Extracellular1 Publication3
Transmembranei385 – 400Beta strandedAdd BLAST16
Topological domaini401 – 402Periplasmic1 Publication2
Transmembranei403 – 417Beta strandedAdd BLAST15
Topological domaini418 – 433Extracellular1 PublicationAdd BLAST16
Transmembranei434 – 443Beta stranded10
Topological domaini444 – 448Periplasmic1 Publication5
Transmembranei449 – 458Beta stranded10
Topological domaini459 – 472Extracellular1 PublicationAdd BLAST14
Transmembranei473 – 490Beta strandedAdd BLAST18
Topological domaini491 – 493Periplasmic1 Publication3
Transmembranei494 – 509Beta strandedAdd BLAST16
Topological domaini510 – 516Extracellular1 Publication7
Transmembranei517 – 529Beta strandedAdd BLAST13
Topological domaini530 – 534Periplasmic1 Publication5
Transmembranei535 – 550Beta strandedAdd BLAST16
Topological domaini551 – 557Extracellular1 Publication7
Transmembranei558 – 572Beta strandedAdd BLAST15
Topological domaini573 – 584Periplasmic1 PublicationAdd BLAST12
Transmembranei585 – 596Beta strandedAdd BLAST12
Topological domaini597 – 601Extracellular1 Publication5
Transmembranei602 – 614Beta strandedAdd BLAST13

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi28L → P: Inactivates uptake. 1 Publication1
Mutagenesisi30V → G or P: Inactivates uptake. 1 Publication1

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB04233 (Hydroxyethyloxy)Tri(Ethyloxy)Octane
DB04039 3-Oxo-Pentadecanoic Acid
DB04147 Lauryl Dimethylamine-N-Oxide

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 201 PublicationAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000347921 – 614Vitamin B12 transporter BtuBAdd BLAST594

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P06129

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P06129

PRoteomics IDEntifications database

More...
PRIDEi
P06129

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Constitutively expressed. Primary control of btuB expression by cobalamin occurs at the level of translation initiation.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TonB.

2 Publications

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4259524, 247 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1083 Vitamin B12 outer membrane transporter complex

Database of interacting proteins

More...
DIPi
DIP-9232N

Protein interaction database and analysis system

More...
IntActi
P06129, 1 interactor

STRING: functional protein association networks

More...
STRINGi
511145.b3966

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1614
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P06129

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P06129

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni108 – 112Cobalamin-binding1 Publication5
Regioni249 – 251Cobalamin-binding1 Publication3
Regioni515 – 518Cobalamin-binding1 Publication4

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi26 – 33TonB box8
Motifi597 – 614TonB C-terminal boxAdd BLAST18

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. [View classification]UniRule annotationCurated

Keywords - Domaini

Signal, TonB box, Transmembrane, Transmembrane beta strand

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105CHI Bacteria
COG4206 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000269547

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P06129

KEGG Orthology (KO)

More...
KOi
K16092

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P06129

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.170.130.10, 1 hit
2.40.170.20, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01531 BtuB, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010101 B12_transptr_BtuB
IPR039426 BtuB-like
IPR012910 Plug_dom
IPR037066 Plug_dom_sf
IPR000531 TonB-dep_rcpt_b-brl
IPR010916 TonB_box_CS
IPR036942 TonB_rcpt_b-brl_sf
IPR010917 TonB_rcpt_CS

The PANTHER Classification System

More...
PANTHERi
PTHR30069 PTHR30069, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07715 Plug, 1 hit
PF00593 TonB_dep_Rec, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01779 TonB-B12, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00430 TONB_DEPENDENT_REC_1, 1 hit
PS01156 TONB_DEPENDENT_REC_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P06129-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKKASLLTA CSVTAFSAWA QDTSPDTLVV TANRFEQPRS TVLAPTTVVT
60 70 80 90 100
RQDIDRWQST SVNDVLRRLP GVDITQNGGS GQLSSIFIRG TNASHVLVLI
110 120 130 140 150
DGVRLNLAGV SGSADLSQFP IALVQRVEYI RGPRSAVYGS DAIGGVVNII
160 170 180 190 200
TTRDEPGTEI SAGWGSNSYQ NYDVSTQQQL GDKTRVTLLG DYAHTHGYDV
210 220 230 240 250
VAYGNTGTQA QTDNDGFLSK TLYGALEHNF TDAWSGFVRG YGYDNRTNYD
260 270 280 290 300
AYYSPGSPLL DTRKLYSQSW DAGLRYNGEL IKSQLITSYS HSKDYNYDPH
310 320 330 340 350
YGRYDSSATL DEMKQYTVQW ANNVIVGHGS IGAGVDWQKQ TTTPGTGYVE
360 370 380 390 400
DGYDQRNTGI YLTGLQQVGD FTFEGAARSD DNSQFGRHGT WQTSAGWEFI
410 420 430 440 450
EGYRFIASYG TSYKAPNLGQ LYGFYGNPNL DPEKSKQWEG AFEGLTAGVN
460 470 480 490 500
WRISGYRNDV SDLIDYDDHT LKYYNEGKAR IKGVEATANF DTGPLTHTVS
510 520 530 540 550
YDYVDARNAI TDTPLLRRAK QQVKYQLDWQ LYDFDWGITY QYLGTRYDKD
560 570 580 590 600
YSSYPYQTVK MGGVSLWDLA VAYPVTSHLT VRGKIANLFD KDYETVYGYQ
610
TAGREYTLSG SYTF
Length:614
Mass (Da):68,407
Last modified:October 1, 1993 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAB43CC46A991FF95
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti162A → G in AAA23524 (PubMed:3882670).Curated1
Sequence conflicti377A → R in AAA23524 (PubMed:3882670).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M10112 Genomic DNA Translation: AAA23524.1
U00006 Genomic DNA Translation: AAC43072.1
U00096 Genomic DNA Translation: AAC76948.1
AP009048 Genomic DNA Translation: BAE77345.1
M57568 Genomic DNA No translation available.
L14556 Genomic DNA Translation: AAA23676.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A65204 QRECBT

NCBI Reference Sequences

More...
RefSeqi
NP_418401.1, NC_000913.3
WP_000591359.1, NZ_SSZK01000065.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC76948; AAC76948; b3966
BAE77345; BAE77345; BAE77345

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
948468

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW3938
eco:b3966

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.2738

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M10112 Genomic DNA Translation: AAA23524.1
U00006 Genomic DNA Translation: AAC43072.1
U00096 Genomic DNA Translation: AAC76948.1
AP009048 Genomic DNA Translation: BAE77345.1
M57568 Genomic DNA No translation available.
L14556 Genomic DNA Translation: AAA23676.1
PIRiA65204 QRECBT
RefSeqiNP_418401.1, NC_000913.3
WP_000591359.1, NZ_SSZK01000065.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1NQEX-ray2.00A21-614[»]
1NQFX-ray2.70A21-614[»]
1NQGX-ray3.31A21-614[»]
1NQHX-ray3.10A21-614[»]
1UJWX-ray2.75A21-614[»]
2GSKX-ray2.10A25-614[»]
2GUFX-ray1.95A21-614[»]
2YSUX-ray3.50A21-614[»]
3M8BX-ray2.44A21-614[»]
3M8DX-ray2.44A21-614[»]
3RGMX-ray2.60A21-614[»]
3RGNX-ray2.30A21-614[»]
SMRiP06129
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi4259524, 247 interactors
ComplexPortaliCPX-1083 Vitamin B12 outer membrane transporter complex
DIPiDIP-9232N
IntActiP06129, 1 interactor
STRINGi511145.b3966

Chemistry databases

DrugBankiDB04233 (Hydroxyethyloxy)Tri(Ethyloxy)Octane
DB04039 3-Oxo-Pentadecanoic Acid
DB04147 Lauryl Dimethylamine-N-Oxide

Protein family/group databases

TCDBi1.B.14.3.1 the outer membrane receptor (omr) family

Proteomic databases

jPOSTiP06129
PaxDbiP06129
PRIDEiP06129

Genome annotation databases

EnsemblBacteriaiAAC76948; AAC76948; b3966
BAE77345; BAE77345; BAE77345
GeneIDi948468
KEGGiecj:JW3938
eco:b3966
PATRICifig|1411691.4.peg.2738

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB0124

Phylogenomic databases

eggNOGiENOG4105CHI Bacteria
COG4206 LUCA
HOGENOMiHOG000269547
InParanoidiP06129
KOiK16092
PhylomeDBiP06129

Enzyme and pathway databases

BioCyciEcoCyc:EG10126-MONOMER
ECOL316407:JW3938-MONOMER
MetaCyc:EG10126-MONOMER

Miscellaneous databases

EvolutionaryTraceiP06129

Protein Ontology

More...
PROi
PR:P06129

Family and domain databases

Gene3Di2.170.130.10, 1 hit
2.40.170.20, 1 hit
HAMAPiMF_01531 BtuB, 1 hit
InterProiView protein in InterPro
IPR010101 B12_transptr_BtuB
IPR039426 BtuB-like
IPR012910 Plug_dom
IPR037066 Plug_dom_sf
IPR000531 TonB-dep_rcpt_b-brl
IPR010916 TonB_box_CS
IPR036942 TonB_rcpt_b-brl_sf
IPR010917 TonB_rcpt_CS
PANTHERiPTHR30069 PTHR30069, 1 hit
PfamiView protein in Pfam
PF07715 Plug, 1 hit
PF00593 TonB_dep_Rec, 1 hit
TIGRFAMsiTIGR01779 TonB-B12, 1 hit
PROSITEiView protein in PROSITE
PS00430 TONB_DEPENDENT_REC_1, 1 hit
PS01156 TONB_DEPENDENT_REC_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBTUB_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P06129
Secondary accession number(s): Q2M8R1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 1, 1988
Last sequence update: October 1, 1993
Last modified: November 13, 2019
This is version 184 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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