UniProtKB - P06127 (CD5_HUMAN)

BLAST

>sp|P06127|CD5_HUMAN T-cell surface glycoprotein CD5 OS=Homo sapiens OX=9606 GN=CD5 PE=1 SV=2
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVC
SQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHS
RNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGS
LGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQ
NSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL
CDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYC
KKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGP
TGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPD
NSSDSDYDLHGAQRL

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History
Entry version 182 (07 Nov 2018)
Sequence version 2 (30 Nov 2010)
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Protein

T-cell surface glycoprotein CD5

Gene

CD5

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

May act as a receptor in regulating T-cell proliferation.

GO - Molecular functionⁱ

scavenger receptor activity Source: InterPro
signaling receptor activity
Source: UniProtKB
Non-traceable author statementⁱ
- 1711157
transmembrane signaling receptor activity
Source: UniProtKB
Non-traceable author statementⁱ
- 3093892

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

apoptotic signaling pathway Source: Ensembl
cell proliferation
Source: UniProtKB
Non-traceable author statementⁱ
- 3093892
cell recognition
Source: UniProtKB
Non-traceable author statementⁱ
- 1711157
T cell costimulation
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Enzyme and pathway databases

SIGNORⁱ	P06127

SIGNORⁱ

P06127

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: T-cell surface glycoprotein CD5 Alternative name(s): Lymphocyte antigen T1/Leu-1 CD_antigen: CD5
Gene namesⁱ	Name:CD5 Synonyms:LEU1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 11

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000110448.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:1685 CD5
MIMⁱ	153340 gene
neXtProtⁱ	NX_P06127

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	25 – 372	ExtracellularSequence analysisAdd BLAST	348
Transmembraneⁱ	373 – 402	HelicalSequence analysisAdd BLAST	30
Topological domainⁱ	403 – 495	CytoplasmicSequence analysisAdd BLAST	93

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	921
Open Targets More...OpenTargetsⁱ	ENSG00000110448
PharmGKBⁱ	PA26224

Chemistry databases

ChEMBLⁱ	CHEMBL3712888

ChEMBLⁱ

CHEMBL3712888

Polymorphism and mutation databases

BioMutaⁱ	CD5
DMDMⁱ	313104090

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 24	Add BLAST		24
ChainⁱPRO_0000033222	25 – 495	T-cell surface glycoprotein CD5Add BLAST		471

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Disulfide bondⁱ	44 ↔ 86	PROSITE-ProRule annotation1 Publication
Disulfide bondⁱ	60 ↔ 125	PROSITE-ProRule annotation1 Publication
Disulfide bondⁱ	81 ↔ 132	PROSITE-ProRule annotation1 Publication
Disulfide bondⁱ	107 ↔ 117	PROSITE-ProRule annotation1 Publication
Glycosylationⁱ	116	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	201 ↔ 267	PROSITE-ProRule annotation
Glycosylationⁱ	241	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	244 ↔ 250	PROSITE-ProRule annotation
Disulfide bondⁱ	285 ↔ 321	PROSITE-ProRule annotation1 Publication
Disulfide bondⁱ	301 ↔ 360	PROSITE-ProRule annotation1 Publication
Disulfide bondⁱ	316 ↔ 367	PROSITE-ProRule annotation1 Publication
Disulfide bondⁱ	342 ↔ 350	PROSITE-ProRule annotation1 Publication
Modified residueⁱ	439	PhosphoserineCombined sources	1
Modified residueⁱ	453	PhosphotyrosineCombined sources	1
Modified residueⁱ	460	PhosphoserineCombined sources	1
Modified residueⁱ	483	PhosphoserineCombined sources	1
Modified residueⁱ	485	PhosphoserineCombined sources	1

Post-translational modificationⁱ

Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.By similarity

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P06127
PaxDbⁱ	P06127
PeptideAtlas More...PeptideAtlasⁱ	P06127
PRIDEⁱ	P06127
ProteomicsDBⁱ	51869

PTM databases

GlyConnectⁱ	589
iPTMnetⁱ	P06127
PhosphoSitePlusⁱ	P06127
SwissPalmⁱ	P06127
UniCarbKBⁱ	P06127

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000110448 Expressed in 101 organ(s), highest expression level in leukocyte
CleanExⁱ	HS_CD5
ExpressionAtlasⁱ	P06127 baseline and differential
Genevisibleⁱ	P06127 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB015392 CAB020308 HPA043416 HPA060839

HPAⁱ

CAB015392
CAB020308
HPA043416
HPA060839

Interactionⁱ

Subunit structureⁱ

Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1 (By similarity).By similarity

Protein-protein interaction databases

BioGridⁱ	107359, 14 interactors
Database of interacting proteins More...DIPⁱ	DIP-21N
IntActⁱ	P06127, 4 interactors
Molecular INTeraction database More...MINTⁱ	P06127
STRINGⁱ	9606.ENSP00000342681

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	35 – 37	Combined sources	3
Beta strandⁱ	39 – 42	Combined sources	4
Beta strandⁱ	45 – 52	Combined sources	8
Beta strandⁱ	55 – 58	Combined sources	4
Helixⁱ	75 – 77	Combined sources	3
Helixⁱ	78 – 83	Combined sources	6
Beta strandⁱ	86 – 88	Combined sources	3
Beta strandⁱ	90 – 94	Combined sources	5
Turnⁱ	101 – 103	Combined sources	3
Beta strandⁱ	104 – 110	Combined sources	7
Beta strandⁱ	117 – 119	Combined sources	3
Beta strandⁱ	122 – 124	Combined sources	3
Beta strandⁱ	126 – 132	Combined sources	7
Beta strandⁱ	275 – 280	Combined sources	6
Beta strandⁱ	286 – 295	Combined sources	10
Beta strandⁱ	298 – 301	Combined sources	4
Helixⁱ	310 – 318	Combined sources	9
Beta strandⁱ	323 – 331	Combined sources	9
Beta strandⁱ	339 – 341	Combined sources	3
Beta strandⁱ	344 – 346	Combined sources	3
Helixⁱ	347 – 349	Combined sources	3
Beta strandⁱ	354 – 356	Combined sources	3
Beta strandⁱ	362 – 367	Combined sources	6

Show more details

3D structure databases

ProteinModelPortalⁱ	P06127
SMRⁱ	P06127
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ

P06127

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	35 – 133	SRCR 1PROSITE-ProRule annotationAdd BLAST	99
Domainⁱ	159 – 268	SRCR 2PROSITE-ProRule annotationAdd BLAST	110
Domainⁱ	276 – 368	SRCR 3PROSITE-ProRule annotationAdd BLAST	93

Keywords - Domainⁱ

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	ENOG410IJ3D Eukaryota ENOG4111C54 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000017536
HOGENOMⁱ	HOG000111490
HOVERGENⁱ	HBG005286
InParanoidⁱ	P06127
KEGG Orthology (KO) More...KOⁱ	K06455
OMAⁱ	MSFHRNH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0G5S
PhylomeDBⁱ	P06127
TreeFamⁱ	TF329295

Family and domain databases

Gene3Dⁱ	3.10.250.10, 2 hits
InterProⁱ	View protein in InterPro IPR001190 SRCR IPR017448 SRCR-like_dom IPR036772 SRCR-like_dom_sf IPR003566 Tcell_CD5
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00530 SRCR, 1 hit
PRINTSⁱ	PR00258 SPERACTRCPTR PR01409 TCELLCD5
SMARTⁱ	View protein in SMART SM00202 SR, 2 hits
SUPFAMⁱ	SSF56487 SSF56487, 2 hits
PROSITEⁱ	View protein in PROSITE PS50287 SRCR_2, 3 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

P06127-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPMGSLQPLA TLYLLGMLVA SCLGRLSWYD PDFQARLTRS NSKCQGQLEV 
        60         70         80         90        100
YLKDGWHMVC SQSWGRSSKQ WEDPSQASKV CQRLNCGVPL SLGPFLVTYT 
       110        120        130        140        150
PQSSIICYGQ LGSFSNCSHS RNDMCHSLGL TCLEPQKTTP PTTRPPPTTT 
       160        170        180        190        200
PEPTAPPRLQ LVAQSGGQHC AGVVEFYSGS LGGTISYEAQ DKTQDLENFL 
       210        220        230        240        250
CNNLQCGSFL KHLPETEAGR AQDPGEPREH QPLPIQWKIQ NSSCTSLEHC 
       260        270        280        290        300
FRKIKPQKSG RVLALLCSGF QPKVQSRLVG GSSICEGTVE VRQGAQWAAL 
       310        320        330        340        350
CDSSSARSSL RWEEVCREQQ CGSVNSYRVL DAGDPTSRGL FCPHQKLSQC 
       360        370        380        390        400
HELWERNSYC KKVFVTCQDP NPAGLAAGTV ASIILALVLL VVLLVVCGPL 
       410        420        430        440        450
AYKKLVKKFR QKKQRQWIGP TGMNQNMSFH RNHTATVRSH AENPTASHVD 
       460        470        480        490 
NEYSQPPRNS HLSAYPALEG ALHRSSMQPD NSSDSDYDLH GAQRL

Length:495

Mass (Da):54,578

Last modified:November 30, 2010 - v2

Checksum:ⁱ9131AEC9683EE1D3

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	F5GYK3	F5GYK3_HUMAN		T-cell surface glycoprotein CD5 T-cell surface glycoprotein CD5	CD5	165	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	289	V → E in BAF85387 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_020411	224	P → L1 PublicationCorresponds to variant dbSNP:rs2241002Ensembl.	1
Natural variantⁱVAR_024649	461	H → RCombined sources5 PublicationsCorresponds to variant dbSNP:rs637186Ensembl.	1
Natural variantⁱVAR_058203	471	A → V4 PublicationsCorresponds to variant dbSNP:rs2229177Ensembl.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X04391 mRNA Translation: CAA27979.1 X89405 AJ237932 Genomic DNA Translation: CAA61584.2 EF064752 Genomic DNA Translation: ABK41935.1 AK292698 mRNA Translation: BAF85387.1 AP000437 Genomic DNA No translation available. BC027901 mRNA Translation: AAH27901.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS8000.1
PIRⁱ	A26396
NCBI Reference Sequences More...RefSeqⁱ	NP_001333385.1, NM_001346456.1 NP_055022.2, NM_014207.3
UniGeneⁱ	Hs.58685

Genome annotation databases

Ensemblⁱ	ENST00000347785; ENSP00000342681; ENSG00000110448
GeneIDⁱ	921
KEGGⁱ	hsa:921
UCSC genome browser More...UCSCⁱ	uc009ynk.4 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P06127	CD5 molecule (Fragment)		HUMAN		463	UniRef100_P06127
UPI0008749C5C		HUMAN		438

Protein	Similar proteins		Species	Score	Length	Source
P06127	CD5 molecule (Fragment)		HUMAN		463	UniRef90_P06127
Uncharacterized protein		NOMLE		592
CD5 isoform 1		PANTR		495
CD5 molecule		GORGO		495
CD5 isoform 1		PONAB		495
+6

Protein	Similar proteins		Species	Score	Length	Source
P06127	CD5 molecule (Fragment)		HUMAN		463	UniRef50_P06127
Uncharacterized protein		NOMLE		592
Uncharacterized protein		PANPA		495
CD5 isoform 1		PONAB		495
CD5 isoform 1		PANTR		495
+12

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X04391 mRNA Translation: CAA27979.1 X89405 AJ237932 Genomic DNA Translation: CAA61584.2 EF064752 Genomic DNA Translation: ABK41935.1 AK292698 mRNA Translation: BAF85387.1 AP000437 Genomic DNA No translation available. BC027901 mRNA Translation: AAH27901.1
CCDSⁱ	CCDS8000.1
PIRⁱ	A26396
RefSeqⁱ	NP_001333385.1, NM_001346456.1 NP_055022.2, NM_014207.3
UniGeneⁱ	Hs.58685

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2JA4	X-ray	2.21	A	270-369	[»]
	2JOP	NMR	-	A	25-134	[»]
	2JP0	NMR	-	A	25-134	[»]
	2OTT	X-ray	2.50	X/Y	276-368	[»]
ProteinModelPortalⁱ	P06127
SMRⁱ	P06127
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	107359, 14 interactors
DIPⁱ	DIP-21N
IntActⁱ	P06127, 4 interactors
MINTⁱ	P06127
STRINGⁱ	9606.ENSP00000342681

Chemistry databases

ChEMBLⁱ	CHEMBL3712888

ChEMBLⁱ

CHEMBL3712888

PTM databases

GlyConnectⁱ	589
iPTMnetⁱ	P06127
PhosphoSitePlusⁱ	P06127
SwissPalmⁱ	P06127
UniCarbKBⁱ	P06127

Polymorphism and mutation databases

BioMutaⁱ	CD5
DMDMⁱ	313104090

Proteomic databases

MaxQBⁱ	P06127
PaxDbⁱ	P06127
PeptideAtlasⁱ	P06127
PRIDEⁱ	P06127
ProteomicsDBⁱ	51869

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	921
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000347785; ENSP00000342681; ENSG00000110448
GeneIDⁱ	921
KEGGⁱ	hsa:921
UCSCⁱ	uc009ynk.4 human

Organism-specific databases

CTDⁱ	921
DisGeNETⁱ	921
EuPathDBⁱ	HostDB:ENSG00000110448.10
GeneCardsⁱ	CD5
H-InvDBⁱ	HIX0009680
HGNCⁱ	HGNC:1685 CD5
HPAⁱ	CAB015392 CAB020308 HPA043416 HPA060839
MIMⁱ	153340 gene
neXtProtⁱ	NX_P06127
OpenTargetsⁱ	ENSG00000110448
PharmGKBⁱ	PA26224
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IJ3D Eukaryota ENOG4111C54 LUCA
GeneTreeⁱ	ENSGT00390000017536
HOGENOMⁱ	HOG000111490
HOVERGENⁱ	HBG005286
InParanoidⁱ	P06127
KOⁱ	K06455
OMAⁱ	MSFHRNH
OrthoDBⁱ	EOG091G0G5S
PhylomeDBⁱ	P06127
TreeFamⁱ	TF329295

Enzyme and pathway databases

SIGNORⁱ	P06127

SIGNORⁱ

P06127

Miscellaneous databases

EvolutionaryTraceⁱ	P06127
GeneWikiⁱ	CD5_(protein)
GenomeRNAiⁱ	921
Protein Ontology More...PROⁱ	PR:P06127
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000110448 Expressed in 101 organ(s), highest expression level in leukocyte
CleanExⁱ	HS_CD5
ExpressionAtlasⁱ	P06127 baseline and differential
Genevisibleⁱ	P06127 HS

Family and domain databases

Gene3Dⁱ	3.10.250.10, 2 hits
InterProⁱ	View protein in InterPro IPR001190 SRCR IPR017448 SRCR-like_dom IPR036772 SRCR-like_dom_sf IPR003566 Tcell_CD5
Pfamⁱ	View protein in Pfam PF00530 SRCR, 1 hit
PRINTSⁱ	PR00258 SPERACTRCPTR PR01409 TCELLCD5
SMARTⁱ	View protein in SMART SM00202 SR, 2 hits
SUPFAMⁱ	SSF56487 SSF56487, 2 hits
PROSITEⁱ	View protein in PROSITE PS50287 SRCR_2, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CD5_HUMAN
Accessionⁱ	P06127Primary (citable) accession number: P06127 Secondary accession number(s): A0N0P4, A8K9I3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 1, 1988
	Last sequence update:	November 30, 2010
	Last modified:	November 7, 2018
	This is version 182 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 11
Human chromosome 11: entries, gene names and cross-references to MIM
Human cell differentiation molecules
CD nomenclature of surface proteins of human leucocytes and list of entries

UniProtKB

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Proteomes

Annotation systems

Supporting data

UniProtKB - P06127 (CD5_HUMAN)

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T-cell surface glycoprotein CD5

CD5

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Plasma Membrane

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ